New Animal Models To Evaluate Therapeutic Targets For Pain Cognitive And Eating Disorders

Download New Animal Models To Evaluate Therapeutic Targets For Pain Cognitive And Eating Disorders full books in PDF, epub, and Kindle. Read online New Animal Models To Evaluate Therapeutic Targets For Pain Cognitive And Eating Disorders ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Animal Models of Pain

Author : Chao Ma
Publisher : Humana Press
ISBN 13 : 9781607618799
Total Pages : 0 pages
Book Rating : 4.6/5 (187 download)

DOWNLOAD NOW!

Book Synopsis Animal Models of Pain by : Chao Ma

Download or read book Animal Models of Pain written by Chao Ma and published by Humana Press. This book was released on 2010-10-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the loss of work days, the price of health care and payments for compensation, litigation, and malpractice, and the overwhelming cost of human suffering, chronic pain syndromes affect humanity enormously on both an economic and personal level. In Animal Models of Pain, expert investigators in the field provide a consolidated review of the current state of pain research by capturing the diversity of animal models that are used to investigate pain mechanisms, which range from surgical incision to mechanical compression and from spinal cord injury to cutaneous/local inflammation and beyond. As a volume in the respected Neuromethods series, this book delivers its vital content through detailed descriptions of a wide variety of step-by-step laboratory methods. Authoritative and cutting-edge, Animal Models of Pain seeks to lead scientists closer to the ultimate goal of improving the quality of life and relieving the unbearable burden of chronic pain for millions of people throughout the world.

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030916785X
Total Pages : 223 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research by : National Research Council

Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Pain Management and the Opioid Epidemic

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!

Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Molecular Mechanisms of Neuropathic Pain and Novel Therapeutic Targets

Author : Wuping Sun
Publisher : Frontiers Media SA
ISBN 13 : 2889744663
Total Pages : 141 pages
Book Rating : 4.8/5 (897 download)

DOWNLOAD NOW!

Book Synopsis Molecular Mechanisms of Neuropathic Pain and Novel Therapeutic Targets by : Wuping Sun

Download or read book Molecular Mechanisms of Neuropathic Pain and Novel Therapeutic Targets written by Wuping Sun and published by Frontiers Media SA. This book was released on 2022-02-22 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Scientific Frontiers in Developmental Toxicology and Risk Assessment

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309070864
Total Pages : 348 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Scientific Frontiers in Developmental Toxicology and Risk Assessment by : National Research Council

Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Molecular Mechanism of Neuroimmune Modulation and Synaptic Plasticity in Acute and Chronic Pain

Author : Linlin Zhang
Publisher : Frontiers Media SA
ISBN 13 : 2832527973
Total Pages : 223 pages
Book Rating : 4.8/5 (325 download)

DOWNLOAD NOW!

Book Synopsis Molecular Mechanism of Neuroimmune Modulation and Synaptic Plasticity in Acute and Chronic Pain by : Linlin Zhang

Download or read book Molecular Mechanism of Neuroimmune Modulation and Synaptic Plasticity in Acute and Chronic Pain written by Linlin Zhang and published by Frontiers Media SA. This book was released on 2023-06-30 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cognitive-Behavioral Therapy for Avoidant/Restrictive Food Intake Disorder

Author : Jennifer J. Thomas
Publisher : Cambridge University Press
ISBN 13 : 1108401155
Total Pages : 195 pages
Book Rating : 4.1/5 (84 download)

DOWNLOAD NOW!

Book Synopsis Cognitive-Behavioral Therapy for Avoidant/Restrictive Food Intake Disorder by : Jennifer J. Thomas

Download or read book Cognitive-Behavioral Therapy for Avoidant/Restrictive Food Intake Disorder written by Jennifer J. Thomas and published by Cambridge University Press. This book was released on 2018-11-15 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines a new cognitive-behavioral treatment for patients of all age groups with avoidant/restrictive food intake disorder.

Pain Models

Author : Hermann O. Handwerker
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496331931
Total Pages : 663 pages
Book Rating : 4.4/5 (963 download)

DOWNLOAD NOW!

Book Synopsis Pain Models by : Hermann O. Handwerker

Download or read book Pain Models written by Hermann O. Handwerker and published by Lippincott Williams & Wilkins. This book was released on 2015-06-01 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: The neurobiology and mechanisms discovered in animals often do not translate to patients with a chronic pain condition. To help researchers and clinicians develop and use models that can help translate data from animals into humans, this book presents experimental animal models, with a focus on how they may translate into humans human experimental pain models, including details about pain induction and assessment human surrogate pain models clinical applications of pain models models that may link mechanisms of pain and pruritus Pain Models contains 29 chapters by internationally recognized experts. It is a comprehensive survey of pain models at different levels, and commentaries by clinicians directly address clinical perspectives. This unique book is unprecedented in its content. It's a quick reminder of the hard work needed to investigate the complex issue of pain perception. With the advent of increasingly sensitive noninvasive investigational tools, the authors want readers to know that basic research is still needed to help develop new drugs. This book will enrich anyone who wishes to know all that goes into conducting pain research with a lab-based pain model.

Recognition and Alleviation of Pain and Distress in Laboratory Animals

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309042755
Total Pages : 161 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Recognition and Alleviation of Pain and Distress in Laboratory Animals by : National Research Council

Download or read book Recognition and Alleviation of Pain and Distress in Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 1992-01-01 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clear guidelines on the proper care and use of laboratory animals are being sought by researchers and members of the many committees formed to oversee animal care at universities as well as the general public. This book provides a comprehensive overview of what we know about behavior, pain, and distress in laboratory animals. The volume explores: Stressors in the laboratory and the animal behaviors they cause, including in-depth discussions of the physiology of pain and distress and the animal's ecological relationship to the laboratory as an environment. A review of euthanasia of lab animals-exploring the decision, the methods, and the emotional effects on technicians. Also included is a highly practical, extensive listing, by species, of dosages and side effects of anesthetics, analgesics, and tranquilizers.

Applications of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders

Author : David H. Barlow
Publisher : Oxford University Press
ISBN 13 : 0190255544
Total Pages : 377 pages
Book Rating : 4.1/5 (92 download)

DOWNLOAD NOW!

Book Synopsis Applications of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders by : David H. Barlow

Download or read book Applications of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders written by David H. Barlow and published by Oxford University Press. This book was released on 2017 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders provides clinicians with a "how to" guide for using the UP to treat a broad range of commonly encountered psychological disorders in adults.

Temporomandibular Disorders

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309670489
Total Pages : 427 pages
Book Rating : 4.3/5 (96 download)

DOWNLOAD NOW!

Book Synopsis Temporomandibular Disorders by : National Academies of Sciences, Engineering, and Medicine

Download or read book Temporomandibular Disorders written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-07-01 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Temporomandibular disorders (TMDs), are a set of more than 30 health disorders associated with both the temporomandibular joints and the muscles and tissues of the jaw. TMDs have a range of causes and often co-occur with a number of overlapping medical conditions, including headaches, fibromyalgia, back pain and irritable bowel syndrome. TMDs can be transient or long-lasting and may be associated with problems that range from an occasional click of the jaw to severe chronic pain involving the entire orofacial region. Everyday activities, including eating and talking, are often difficult for people with TMDs, and many of them suffer with severe chronic pain due to this condition. Common social activities that most people take for granted, such as smiling, laughing, and kissing, can become unbearable. This dysfunction and pain, and its associated suffering, take a terrible toll on affected individuals, their families, and their friends. Individuals with TMDs often feel stigmatized and invalidated in their experiences by their family, friends, and, often, the health care community. Misjudgments and a failure to understand the nature and depths of TMDs can have severe consequences - more pain and more suffering - for individuals, their families and our society. Temporomandibular Disorders: Priorities for Research and Care calls on a number of stakeholders - across medicine, dentistry, and other fields - to improve the health and well-being of individuals with a TMD. This report addresses the current state of knowledge regarding TMD research, education and training, safety and efficacy of clinical treatments of TMDs, and burden and costs associated with TMDs. The recommendations of Temporomandibular Disorders focus on the actions that many organizations and agencies should take to improve TMD research and care and improve the overall health and well-being of individuals with a TMD.

Improving and Accelerating Therapeutic Development for Nervous System Disorders

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309292492
Total Pages : 107 pages
Book Rating : 4.3/5 (92 download)

DOWNLOAD NOW!

Book Synopsis Improving and Accelerating Therapeutic Development for Nervous System Disorders by : Institute of Medicine

Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2014-02-06 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.

Animal Models for the Study of Human Disease

Author : P. Michael Conn
Publisher : Academic Press
ISBN 13 : 0124159125
Total Pages : 1109 pages
Book Rating : 4.1/5 (241 download)

DOWNLOAD NOW!

Book Synopsis Animal Models for the Study of Human Disease by : P. Michael Conn

Download or read book Animal Models for the Study of Human Disease written by P. Michael Conn and published by Academic Press. This book was released on 2013-05-29 with total page 1109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. - Organized by disease orientation for ease of searchability - Provides information on locating resources, animal alternatives and animal ethics - Covers a broad range of animal models used in research for human disease

Oxford Guide to Behavioural Experiments in Cognitive Therapy

Author : Khadj Rouf
Publisher : OUP Oxford
ISBN 13 : 019100491X
Total Pages : 496 pages
Book Rating : 4.1/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Oxford Guide to Behavioural Experiments in Cognitive Therapy by : Khadj Rouf

Download or read book Oxford Guide to Behavioural Experiments in Cognitive Therapy written by Khadj Rouf and published by OUP Oxford. This book was released on 2004-05-06 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioural experiments are one of the central and most powerful methods of intervention in cognitive therapy. Yet until now, there has been no volume specifically dedicated to guiding physicians who wish to design and implement behavioural experiments across a wide range of clinical problems. The Oxford Guide to Behavioural Experiments in Cognitive Therapy fills this gap. It is written by clinicians for clinicians. It is a practical, easy to read handbook, which is relevant for practising clinicians at every level, from trainees to cognitive therapy supervisors. Following a foreword by David Clark, the first two chapters provide a theoretical and practical background for the understanding and development of behavioural experiments. Thereafter, the remaining chapters of the book focus on particular problem areas. These include problems which have been the traditional focus of cognitive therapy (e.g. depression, anxiety disorders), as well as those which have only more recently become a subject of study (bipolar disorder, psychotic symptoms), and some which are still in their relative infancy (physical health problems, brain injury). The book also includes several chapters on transdiagnostic problems, such as avoidance of affect, low self-esteem, interpersonal issues, and self-injurious behaviour. A final chapter by Christine Padesky provides some signposts for future development. Containing examples of over 200 behavioural experiments, this book will be of enormous practical value for all those involved in cognitive behavioural therapy, as well as stimulating exploration and creativity in both its readers and their patients.

Oxford Textbook of Neurorehabilitation

Author : Volker Dietz
Publisher : Oxford University Press
ISBN 13 : 0192558455
Total Pages : pages
Book Rating : 4.1/5 (925 download)

DOWNLOAD NOW!

Book Synopsis Oxford Textbook of Neurorehabilitation by : Volker Dietz

Download or read book Oxford Textbook of Neurorehabilitation written by Volker Dietz and published by Oxford University Press. This book was released on 2020-05-28 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurorehabilitation is an expanding field with an increasing clinical impact due to an ageing population. During the last 20 years, neurorehabilitation has developed from a discipline with little scientific background, separated from other medical centers, to a medical entity largely based on the principles of 'evidenced based medicine' with strong ties to basic research and clinical neurology. Today neurorehabilitation is still a work in progress and treatment standards are not yet established for all aspects of the field. There are very few books that address contemporary neurorehabilitation from this perspective. This new edition of the Oxford Textbook of Neurorehabilitation provides an understanding of the theoretical underpinnings of the subject as well as a clear perspective on how (and why) to approach treatment decisions on an individualized basis. The book has been thoroughly updated to reflect novel important developments in the field and includes new chapters on vocational rehabilitation, self-management strategies in neurorehabilitation, and music supported therapy in neurorehabilitation. This indispensable book will be of great interest to rehabilitation physicians, neurologists, and allied health care professionals who look after patients requiring neurorehabilitation.

Translational Pain Research

Author : Lawrence Kruger
Publisher : CRC Press
ISBN 13 : 1439812101
Total Pages : 458 pages
Book Rating : 4.4/5 (398 download)

DOWNLOAD NOW!

Book Synopsis Translational Pain Research by : Lawrence Kruger

Download or read book Translational Pain Research written by Lawrence Kruger and published by CRC Press. This book was released on 2009-11-24 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical

Sigma Receptors

Author : Stephen T. Safrany
Publisher : Frontiers Media SA
ISBN 13 : 2889661024
Total Pages : 215 pages
Book Rating : 4.8/5 (896 download)

DOWNLOAD NOW!

Book Synopsis Sigma Receptors by : Stephen T. Safrany

Download or read book Sigma Receptors written by Stephen T. Safrany and published by Frontiers Media SA. This book was released on 2020-10-27 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.