Neuropeptides And Stress

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Neuropeptides and Stress

Author : Yvette Tache
Publisher : Springer Science & Business Media
ISBN 13 : 1461235146
Total Pages : 360 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Neuropeptides and Stress by : Yvette Tache

Download or read book Neuropeptides and Stress written by Yvette Tache and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropeptides and Stress presents a comprehensive survey by leading pioneers in the field of the knowledge and concepts implicating neuropeptides in the regulations of responses to stress. Topics covered include: recent advances on the regulation and modulation of the behavioral, endocrine, autonomic, gastrointestinal, immune and analgesic responses to stress by neuropeptides. Neuroanatomical and biological data are considered. Special emphasis is given to corticotropin-releasing factor (CRF) and opioid peptides.

Neuropeptides

Author : Fleur L. Strand
Publisher : MIT Press
ISBN 13 : 9780262194075
Total Pages : 678 pages
Book Rating : 4.1/5 (94 download)

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Book Synopsis Neuropeptides by : Fleur L. Strand

Download or read book Neuropeptides written by Fleur L. Strand and published by MIT Press. This book was released on 1999 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. In recent years there has been increasing interest and, subsequently, active research in neuropeptides. These neuroactive molecules coordinate, integrate, and regulate physiological processes in all organisms, throughout all phases of development. Acting as neurohormones, neurotransmitters, and/or neuromodulators, they maintain physiological homeostasis and influence important behavioral patterns. This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. The book is divided into two parts. In Part I the author defines the basic principles of neuropeptide action, including their biosynthesis, processing, transport, distribution, and interactions with receptors and second messenger systems. Strand also discusses the intimate interaction between the neuropeptides, stress, and the immune system. In Part II she discusses the regulatory functions of the families of neuropeptide in sufficient detail to provide both the advanced student and senior investigator with a thorough understanding of the most important neuropeptides. The text also contains a complete and up-to-date reference/reading list.

Stress, Neuropeptides, and systemic disease

Author : James McCubbin
Publisher : Academic Press
ISBN 13 : 032314800X
Total Pages : 502 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Stress, Neuropeptides, and systemic disease by : James McCubbin

Download or read book Stress, Neuropeptides, and systemic disease written by James McCubbin and published by Academic Press. This book was released on 2012-12-02 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress, Neuropeptides, and Systemic Disease traces the development of the neuropeptide hypothesis from its anatomical substrate to its functional correlates in animal and pre-clinical human models of stress-induced disease. The book contains articles that discuss the different aspects and findings on the study of neuropeptides such as the histochemical localization of peptide-containing cells and peptidergic receptors; the current concepts in hypothalamo-pituitary-adrenal axis regulation; neuropeptides involved in stress and their distribution in the mammalian central nervous system; and neuropeptide-mediated regulation of the neuroendocrine and autonomic responses to stress. The methods of measuring neuropeptides and their metabolism; stress responses and the pathogenesis of arthritis; brain peptides and gastrointestinal transit; and diminished opioid inhibition of blood pressure and pituitary function in hypertension development are presented as well. Physicians, neurobiologists, pharmacologists, and biological scientists will find the book very interesting.

Neuropeptides and Stress

Author : Yvette Taché
Publisher :
ISBN 13 : 9783540967484
Total Pages : 345 pages
Book Rating : 4.9/5 (674 download)

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Book Synopsis Neuropeptides and Stress by : Yvette Taché

Download or read book Neuropeptides and Stress written by Yvette Taché and published by . This book was released on 1989 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neuropeptides and Behaviour: From Motivation to Psychopathology

Author : Deborah Suchecki
Publisher : Frontiers Media SA
ISBN 13 : 2889453073
Total Pages : 148 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Neuropeptides and Behaviour: From Motivation to Psychopathology by : Deborah Suchecki

Download or read book Neuropeptides and Behaviour: From Motivation to Psychopathology written by Deborah Suchecki and published by Frontiers Media SA. This book was released on 2017-10-12 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of the involvement of neuropeptides with behaviours other than regulatory motivated ones took place in the midst of 1960’s with David de Wied’s first report on the influence of pituitary peptides on memory. This major scientific breakthrough opened a new frontier of studies in Endocrinology and its related fields, Neuroendocrinology and Psychoneuroendocrinology. Neuropeptides were initially thought to be involved in homeostatic regulation and secreted only from neurons located in the hypothalamus; they are now recognized neurotransmitters, produced in and secreted from distinct brain areas, associated with a myriad of, not only, motivated, but also psychopathological behaviours. Motivated behaviours are determinant for individual and species survival, but their expression in a large spectrum and deviations from average may give rise to a number of psychiatric conditions.

Magnesium in the Central Nervous System

Author : Robert Vink
Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

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Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Galanin

Author : Tomas Hökfelt
Publisher : Springer Science & Business Media
ISBN 13 : 3034602286
Total Pages : 285 pages
Book Rating : 4.0/5 (346 download)

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Book Synopsis Galanin by : Tomas Hökfelt

Download or read book Galanin written by Tomas Hökfelt and published by Springer Science & Business Media. This book was released on 2010-08-18 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Galanin is a neuropeptide found both in the central and peripheral nervous system. The 29-amino acid peptide (named after its N-terminal glycine and C-terminal alanine) was identified in 1983 by its C-terminal amidation. This 'reverse' approach, that is to discover a substance through a distinct chemical feature, and only subsequently to characterize its biological activity, was novel and has been successful in the identification of several other peptides. After the structure of galanin was determined in 1983, functional studies were performed with material purified from natural sources until the synthetic form of the peptide became available. Galanin can act as transmitter, modulator and trophic factor, and is involved in a number of physiological processes such as hormone secretion, cardiovascular mechanisms, feeding and cognition. This peptide may also be of significance for a number of pathological processes/disorders including pain, depression, Alzheimer's disease, epilepsy, addiction and cancer. This wide diversity of actions is mediated by three galanin receptor subtypes. The studies reviewed in this volume give a fairly complete overview of the spectrum of the biological actions and functions of galanin and its receptors and on possible therapeutic applications in a number of pathological conditions.

Stress

Author : S. Clare Stanford
Publisher :
ISBN 13 :
Total Pages : 476 pages
Book Rating : 4.X/5 (2 download)

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Book Synopsis Stress by : S. Clare Stanford

Download or read book Stress written by S. Clare Stanford and published by . This book was released on 1993 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress: From Synapse to Syndrome attempts to break down the barriers which researchers and students encounter when trying to consolidate the findings from the areas of psychology, physiology, and clinical science. It fills a gap in the literature by presenting basic physiological and psychological research on stress in a manner comprehensible to all research disciplines. It also covers the clinical material about the effects of stress in a coherent manner. The scope of the book ranges from discussions of common experimental procedures, and the rationale behind them, to up-to-date information by those already familiar with the field. In this way it links clinical work with that done on animals, on the one hand, and on the other, neurochemical changes with physiological findings. The focus of each section is to explain the variation between individuals in the impact of stress, through an understanding of mechanisms which affect resistance to it. The book makes significant progress in defining barriers and will ultimately inspire further research, particularly in the relatively new area of post-traumatic stress disorder. Key Features * Integrates research on stress from several disciplines, including pharmacology, physiology, and psychology * Covers physiological basis of stress-linked clinical disorders, use of animal models, role of major neurotransmitters, and future prospects for stress research

Neuropeptide Y and Related Peptides

Author : Martin C. Michel
Publisher : Springer Science & Business Media
ISBN 13 : 3642187641
Total Pages : 556 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Neuropeptide Y and Related Peptides by : Martin C. Michel

Download or read book Neuropeptide Y and Related Peptides written by Martin C. Michel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: After a little more than 20 years since the original discovery of neuropeptide Y (NPY) by Tatemoto and colleagues, the field of NPY research has made remarkable progress and is coming of age.The present volume addresses all major topics in connection with NPY and related peptides by established leaders in their respective areas. Experienced NPY-aficionados will certainly find new and useful additional information in this volume and newcomers to the field will hopefully discover how much exciting research this still has to offer.

A New Era of Catecholamines in the Laboratory and Clinic

Author : Lee E. Eiden
Publisher : Academic Press
ISBN 13 : 012411539X
Total Pages : 500 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis A New Era of Catecholamines in the Laboratory and Clinic by : Lee E. Eiden

Download or read book A New Era of Catecholamines in the Laboratory and Clinic written by Lee E. Eiden and published by Academic Press. This book was released on 2013-09-17 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Advances in Pharmacology presents catecholamine symposium proceedings. Chapters cover such topics as cellular dynamics of catecholamine release and re-uptake, catecholamines in mood regulation and imaging catecholamine transporters. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. Presents catecholamine symposium proceedings Chapters cover a variety of topics such as cellular dynamics of catecholamine release and re-uptake, catecholamines in mood regulation and imaging catecholamine transporters With the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike

Neuropeptide Receptors in the Amygdala

Author : Katherine L. Eaton
Publisher :
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.:/5 (317 download)

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Book Synopsis Neuropeptide Receptors in the Amygdala by : Katherine L. Eaton

Download or read book Neuropeptide Receptors in the Amygdala written by Katherine L. Eaton and published by . This book was released on 2007 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress is a known factor in psychiatric illness. Understanding the mechanisms by which stress precipitates these illnesses are of paramount concern. Since anxiety disorder are highly comorbid with mood disorders, understanding the common symptoms of these illnesses could indicate functional changes that elicit these symptoms. Also, alterations in the hypothalamo-pituitary-adrenal (HPA) axis, the system involved in maintaining homeostasis, are observed in many mood and anxiety disorders. The amygdala has been shown to modulate anxiety behavior and HPA axis function. The amygdala receives inputs from many sensory cortices and has projections reaching the hypothalamus and mid- and hindbrain regions. These connections allow integration of sensory signal and can produce the necessary signaling to induce responses to maintain homeostasis following stress. This signaling occurs through various neurotransmitters. The longest lasting and farthest reaching of these are neuropeptides. Two neuropeptides, corticotropin-releasing hormone (CRH) and neuropeptide Y (NPY), have been shown to alter anxiety behavior and HPA axis function. These changes are mediated through multiple receptors. This dissertation endeavors to understand how certain CRH and NPY receptors are regulated by glucocorticoid and chronic stress. The receptors to be investigated in this thesis include the CRH type 2 receptor (CRH-R2), NPY type 1 receptor (NPY-Y1) and the glucocorticoid induced receptor (GIR). In vitro analysis was used to investigate changes in the expression of CRH-R2, NPY-Y1 and GIR following glucocorticoid exposure. CRH-R2 and GIR could be down regulated by glucocorticoids and NPY-Y1 was up regulated. Possible mechanisms for these dexamethasone-mediated changes are discussed. In vivo studies determined the regulation of CRH-R2, NPY-Y1 and GIR expression by chronic stress in the central and medial amygdala, both known to mediate anxiety behavior and HPA axis function. The Chronic Variable Stress (CVS) paradigm used is known to elicit changes similar to those observed in depression, such as altered HPA axis function, increased anxiety and anhedonia. Alteration in neuropeptide receptor expression could contribute to these changes. In the central amygdala, CRH-R2 is down regulated following 14 days of CVS, while NPY-Y1 and GIR had no effect. In the medial amygdala, GIR is up regulated while CRH-R2 and NPY-Y1 are unchanged.

Handbook of Neurochemistry and Molecular Neurobiology

Author : Ramon Lim
Publisher : Springer Science & Business Media
ISBN 13 : 0387303480
Total Pages : 691 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Handbook of Neurochemistry and Molecular Neurobiology by : Ramon Lim

Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Ramon Lim and published by Springer Science & Business Media. This book was released on 2006-09-18 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition."--Publisher's website.

Neuropeptides in Stress Reactivity

Author : Irene Melo de Carvalho
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (17 download)

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Book Synopsis Neuropeptides in Stress Reactivity by : Irene Melo de Carvalho

Download or read book Neuropeptides in Stress Reactivity written by Irene Melo de Carvalho and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stress and Skin Disorders

Author : Katlein França
Publisher : Springer
ISBN 13 : 3319463527
Total Pages : 257 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Stress and Skin Disorders by : Katlein França

Download or read book Stress and Skin Disorders written by Katlein França and published by Springer. This book was released on 2016-12-16 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermatological conditions are intimately related to stress. Stress can affect, reveal or even exacerbate a number of skin disorders, including alopecia, seborrheic dermatitis, psoriasis, atopic dermatitis, pruritus, herpes, lichen planus, rosacea and urticarial. On the other hand, the skin disease itself could induce a secondary stress for the patient, influencing his or her quality of life. There is increasing evidence that stress influences disease processes and contributes to inflammation through the modulating hypothalamicpituitary- adrenal axis – releasing neuropeptides, neurotrophins, lymphokines and other chemical mediators from nerve endings to dermal cells. This is one of the first books published on this topic, focusing more on the basic science aspects of stress in dermatopathology (oxidants, antioxidants, and oxidative injury in dermatopathology, dermatopharmacology, and dermatotoxicology.) Most Psychodermatology texts adopt a practical approach to identify all types of Psychodermatology disorders, focusing on clinical treatment. This concise title offers a comprehensive and didactic approach to skin diseases caused or exacerbated by stress, as well as covers the immunology, role and effect of stress on skin disease, and quality of life in dermatology. In the current programs of medical residency in dermatology, little is taught about the relationship between stress and skin diseases and this book is an important tool for young dermatologists and psychodermatologists in training.

Psychoneuroimmunology, Stress, and Infection

Author : Herman Friedman
Publisher : CRC Press
ISBN 13 : 1000722554
Total Pages : 312 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Psychoneuroimmunology, Stress, and Infection by : Herman Friedman

Download or read book Psychoneuroimmunology, Stress, and Infection written by Herman Friedman and published by CRC Press. This book was released on 2020-02-03 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychoneuroimmunology is the emerging science devoted to studying the two-way relationship between the nervous and immune systems. Psychoneuroimmunology, Stress, and Infection highlights the latest information concerning microbial infections in both man and animals as related to stress and especially stress hormones. The volume focuses on psychoneuroimmunology as it impacts the immune system in general and also the relationship between neurological events which influence susceptibility and/or resistance to infectious agents such as bacteria, fungi and viruses, as well as parasites. Prominent researchers describe the involvement of the hypothalamus-pituitary-adrenal (HPA) axis on immunity as a function of the nervous system. The text discusses hormones such as prolactin and growth hormone and steroid induced susceptibility to infection and neuropeptides, including vasoactive intestinal peptide, and substance P. The effects of catacholamines on immunity and susceptibility to infection are also covered. This reference also details the involvement of immune cells in the synthesis of neuropeptides, including hormones and endorphins, their effect on the brain as well as the effects of interleukins and tumor necrosis factor on the central nervous system. The book concludes with an interesting look at the relationship between aging, psychoneuroimmunology, and infection. Although there is much new knowledge concerning the nature and mechanism of immune responses, including the mediators involved, Psychoneuroimmunology, Stress, and Infection also presents important discussions and reviews that are long overdue and provide a major contribution to the area of biomedical knowledge in general and psychoneuroimmunology in particular.

Neuropeptides in Neuroprotection and Neuroregeneration

Author : Fred Nyberg
Publisher : CRC Press
ISBN 13 : 1439830622
Total Pages : 321 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Neuropeptides in Neuroprotection and Neuroregeneration by : Fred Nyberg

Download or read book Neuropeptides in Neuroprotection and Neuroregeneration written by Fred Nyberg and published by CRC Press. This book was released on 2012-06-19 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the genomic era is no longer in its infancy, the life sciences are still facing questions about the role of endogenous proteins and peptides in homeostasis and pathologies. Delving into one of the most current fields of interest in biology and medicine, Neuropeptides in Neuroprotection and Neuroregeneration describes the impact of neuropeptides on neuroprotection and neuroregeneration. The book begins with chapters describing important features of the endogenous neuropeptide systems related to their formation, receptor signaling, and inactivation. It includes chapters focused on the design and development of peptide-like drugs (peptidomimetics). In addition, the book covers: General aspects regarding the biosynthesis, structures, and distribution of neuroactive peptides and their receptors Basic mechanisms for neuropeptide action, metabolism, as well as techniques for their detection and aspects essential for the cellular mechanisms underlying brain pathology Neuropeptides known for their impact in neurodegenerative and neuroprotective processes Fundamental aspects as well as recent progress in the development of peptidomimetics of neuroprotective and cognition-enhancing peptides

Enkephalins and Endorphins

Author : R.E. Faith
Publisher : Springer Science & Business Media
ISBN 13 : 148990557X
Total Pages : 440 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Enkephalins and Endorphins by : R.E. Faith

Download or read book Enkephalins and Endorphins written by R.E. Faith and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Is this a time for a sleeping giant to rise? We have known since study of the lymphocyte and plasma cells really began in earnest in the early 1940's that the pituitary adrenal axis under intimate control of the hypothalamus could influence immunological functions profoundly. We have also known for at least 20 years in my recollection that female sex hor mones can maximize certain immunity functions while male sex hormones tend to suppress many immunological reactions. The thyroid hormones accelerate antibody production while at the same time sp~eding up de gradation of antibodies and immunoglobulins and thyroidectomy decreases the rate of antibody production. Further, much evidence has accumulated indicating that the brain, yes even the mind, can influence in significant ways susceptibility to infections, cancers and to development of a variety of autoimmune diseases. More than 20 years ago, my colleagues and I convinced ourselves, if no one else, that hypnosis can exert major in fluences on the effector limb of the classical atopic allergic reactions. We showed with Aaron Papermaster that the Prausnitz-Kustner reaction may be greatly inhibited, indeed largely controlled, by post-hypnotic suggestion. And it was not even necessary for us to publish our discovery because scientists in John Humphrey's laboratory at Mill Hill Research Center in London had beaten us to the punch. They described hypnotic control of both the PK reaction and delayed allergic reactions to tuberculin by hypnosis.