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Neuronal Degeneration And Regeneration From Basic Mechanisms To Prospects For Therapy
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Book Synopsis Neuronal Degeneration and Regeneration: From Basic Mechanisms to Prospects for Therapy by : F.W. Van Leeuwen
Download or read book Neuronal Degeneration and Regeneration: From Basic Mechanisms to Prospects for Therapy written by F.W. Van Leeuwen and published by Elsevier. This book was released on 1998-11-09 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the result of the 20th International Summer School in Brain Research, organized in August 1997 in Amsterdam, by the Netherlands Institute for Brain Research at the Royal Netherlands Academy of Sciences. It is the first book that provides a complete overview of the field of neurodegeneration and regeneration including spinal cord injury, neurodegenerative diseases and therapy. Divided into five sections, the first two sections give an overview of fundamental research on nerve cell death, neuronal survival, neurite outgrowth and guidance. Extensive attention is given to the role of neurotrophins, their receptor tyrosine kinases and cell-adhesion molecules in development and regeneration of the nervous system. The third section of the book is devoted to research involving human neurodegenerative diseases and emerging treatment strategies. Section four focusses on recent advances in the understanding of pathophysiological mechanisms underlying neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases along with prion diseases. Novel insights into the neuropathological hallmarks of these diseases, as well as into transgenic animal models, the involvement of environmental factors, and genomic and mRNA changes that can cause neurodegeneration. The final section of this volume reveals recent developments in the use of cell and gene therapy to treat neurodegenerative disease and lesion-related deficits. Implantation of genetically modified cells, direct gene transfer with viral vectors and the first clinical trials with encapsulated genetically modified cells in patients suffering from amyotrophic lateral scelerosis are examples of new therapeutic strategies treating neurodegenerative diseases. The book is of particular interest to departments of neuroscience, neurological clinics and departments, the pharmalogical industry and medical libraries.
Book Synopsis Neuronal degeneration and regeneration: from basic mechanisms to prospects for therapy by :
Download or read book Neuronal degeneration and regeneration: from basic mechanisms to prospects for therapy written by and published by . This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neuronal Degeneration and Regeneration by :
Download or read book Neuronal Degeneration and Regeneration written by and published by . This book was released on 1998 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Degeneration and Regeneration in the Nervous System by : Norman Saunders
Download or read book Degeneration and Regeneration in the Nervous System written by Norman Saunders and published by CRC Press. This book was released on 2003-09-02 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Degeneration and Regeneration in the Nervous System brings together an international team of contributors to produce a series of critical reviews appraising key papers in the field. The pace of research on brain and spinal cord injury quickened considerably in the last ten years and there is much that is new and important that is covered in this book. However, there is still a long way to go before our knowledge will explain fully why the central nervous system has such a limited capacity for regeneration, and before experimental solutions can be applied to the patient. With emphasis on actual and therapeutic importance of the work reviewed, Degeneration and Regeneration in the Nervous System is a useful overview for graduate students, their teachers and researchers working in this field.
Book Synopsis Advances in CNS Repair, Regeneration, and Neuroplasticity: From Basic Mechanisms to Therapeutic Strategies by : Shuxin Li
Download or read book Advances in CNS Repair, Regeneration, and Neuroplasticity: From Basic Mechanisms to Therapeutic Strategies written by Shuxin Li and published by Frontiers Media SA. This book was released on 2022-03-09 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Regeneration of Nerves and Spinal Cord by : Lars P. Klimaschewski
Download or read book The Regeneration of Nerves and Spinal Cord written by Lars P. Klimaschewski and published by Springer Nature. This book was released on with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neurodegenerative Disorders by : D. L. Price
Download or read book Neurodegenerative Disorders written by D. L. Price and published by . This book was released on 1991-12-20 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dahlem Workshop Reports Life Sciences Research Report 51 Neurodegenerative Disorders Mechanisms and Prospects for Therapy Edited by D.L. Price, H. Thoenen and A.J. Aguayo Neurological disorders, particularly the neurodegenerative diseases involving the central nervous system, are characterized by dysfunction and death of specific populations of nerve cells. Cellular and molecular neurobiological strategies have begun to clarify the mechanisms of neuronal degeneration and have led to the design of new approaches to prevent cell degeneration, promote cell survival, and restore the functions of diseased nerve cells. This book provides new information concerning these processes. Background papers review exciting new developments concerning: (a) the mechanisms of neuronal degeneration caused by genetic factors, excitotoxins, and calcium; (b) the molecular pathology leading to abnormalities in Alzheimer’s disease and the spongiform encephalopathies or prion diseases; (c) the biological substrates of cell differentiation, axon guidance, and target recognition during development, repair, and recovery; and (d) the potential therapeutic efficacies of growth factors and grafted cells in re-establishing circuits essential for the restoration of function. The group discussions and background papers in this Dahlem Workshop Report communicate both the excitement and enthusiasm of the participants facing the scientific challenges that are part of this important area of neurobiological research. This volume will be of special interest to professionals in the fields of molecular/cell biology, genetics, neuroanatomy, neurochemistry, developmental neurobiology, and neuropathology as well as clinicians working in neurology and psychiatry. Goal of this Dahlem Workshop: to understand the molecular and cellular mechanisms of neurological disease and to explore new approaches to treatment.
Book Synopsis Peripheral and Spinal Mechanisms in the Neural Control of Movement by : M.D. Binder
Download or read book Peripheral and Spinal Mechanisms in the Neural Control of Movement written by M.D. Binder and published by Elsevier. This book was released on 1999-12-17 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, we have witnessed a striking maturation of our understanding of how neurons in the spinal cord control muscular activity and movement. Paradoxically, a host of new findings have revealed an unexpected versatility in the behavior of these well-studied neural elements and circuits. In this volume, the world's leading experts review the current state of our knowledge of motor control, outline their latest results and developments, and delineate the seminal unresolved questions in this vibrant field of research. The volume begins with a commentary and overview of our current understanding of the peripheral and spinal basis of motor control. The remainder of the volume is divided into seven sections, each focused on a different problem. The first chapter in each section provides some historical review and presages the experimental findings and hypotheses that are discussed in subsequent chapters.Topics include the biomechanics of neuromuscular systems, the properties of motoneurons and the muscle units they control, spinal interneurons, pattern generating circuits, locomotion, descending control of spinal circuits, comparative physiology of motor systems, and motor systems neurophysiology studied in man. The book serves as a unique reference volume and should be essential reading for anyone interested in motor systems. Moreover, the volume's comprehensive coverage of a wide range of topics make it an effective textbook for graduate level courses in motor control neurobiology, kinesiology, physical therapy, and rehabilitation medicine.
Book Synopsis Brain Mechanisms for the Integration of Posture and Movement by :
Download or read book Brain Mechanisms for the Integration of Posture and Movement written by and published by Elsevier. This book was released on 2003-10-30 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Mechanisms for the Integration of Posture and Movement
Book Synopsis Vision: From Neurons to Cognition by : C. Casanova
Download or read book Vision: From Neurons to Cognition written by C. Casanova and published by Gulf Professional Publishing. This book was released on 2001-10-25 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Internationally renowned researchers discuss how the various parts of the brain process and integrate visual signals, providing up to date original findings, reviews, and theoretical proposals on visual processing. This book addresses the basic mechanisms of visual perception as well as issues such as neuronal plasticity, functional reorganization and recovery, residual vision, and sensory substitution. Knowledge of the basic mechanisms by which our brain can analyze, reconstruct, and interpret images in the external world is of fundamental importance for our capacity to understand the nature and causes of visual deficits, such as those resulting from ischemia, abnormal development, neuro-degenerative disorders, and normal aging. It is also essential to our goal of developing better therapeutic strategies, such as early diagnosis, visual training, behavioral rehabilitation of visual functions, and visual implants.
Book Synopsis Neural Control of Space Coding and Action Production by : C. Prablanc
Download or read book Neural Control of Space Coding and Action Production written by C. Prablanc and published by Gulf Professional Publishing. This book was released on 2003-02-28 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical neuropsychology has evolved by integrating in its field the knowledge derived from neuroanatomical, electrophysiological and psychophysical data, and has led to the development of rehabilitation tools. This volume tries to link the new concepts and discoveries in the field of sensorimotor coordination. It contains the main contributions of participants of an international symposium held in Lyon in 2001 entitled "Neural control of space coding and action production". The book emphasizes the reciprocal relationship between perception and action, and the essential role of active sensorimotor organization or reorganization in building up perceptual and motor representations of the self and of the external world.
Book Synopsis Vasopressin and Oxytocin: From Genes to Clinical Applications by : D. Poulain
Download or read book Vasopressin and Oxytocin: From Genes to Clinical Applications written by D. Poulain and published by Elsevier. This book was released on 2002-10-24 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: The articles comprising this volume were first presented at the World Congress on Neurohypophysial Hormones held in Bordeaux, France on September 8-12, 2001. This conference brought together more than 170 scientists from 18 countries who belong to the different fields of interest representing research in the hypothalamo-neurohypophysial system. Two neurohypophysial neurohormones, oxytocin and vasopressin, exert a variety of central and peripheral actions and thus involve different scientific domains, which too often, even today, do not always find the appropriate occasion to interact. This volume is composed of chapters dealing with topics varying from basic and clinical neurosciences and neuroendocrinology, to reproductive, renal, cardiovascular physiology and pathology. It encompasses all areas of current neurohypophysial research and should be of vital interest as an integrative reference volume to specialized investigators and as an excellent introductory text to students, scientists and clinicians not yet closely familiar with the field. To ensure novelty and to make sure that all topics of current importance were covered, plenary and symposium speakers as well as poster presentations concentrated on recent advances made in the last few years.
Book Synopsis Plasticity in the Adult Brain: From Genes to Neurotherapy by : M.A. Hofman
Download or read book Plasticity in the Adult Brain: From Genes to Neurotherapy written by M.A. Hofman and published by Elsevier. This book was released on 2002-10-23 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade neuronal plasticity has become a major theme of modern neurobiology, from cellular and molecular mechanisms of synapse formation in worms and insects to behavioural recovery from strokes in elderly humans. For this reason the focus of interest in the present volume of Progress in Brain Research is on the topic of neuroplasticity in mature organisms, including humans. Contributions range from neurogenesis and synaptic plasticity in the adult primate brain, to neural mechanisms of learning and memory, and the influence of environmental factors and aging on the functional potential of the central nervous system. Several contributions focus on recent developments in neural regeneration and brain repair, providing challenging evidence that the use of stem cell neurotherapy may be beneficial to humans suffering from various neurological and psychiatric diseases. This volume integrates new information on the cellular and molecular mechanisms of neuroplasticity and highlights challenging future questions in this exciting and topical area of neuroscience.
Book Synopsis Acetylcholine in the Cerebral Cortex by : L. Descarries
Download or read book Acetylcholine in the Cerebral Cortex written by L. Descarries and published by Elsevier. This book was released on 2004 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive exposé, by leading neuroscientists, of current knowledge on the neurotransmitter acetylcholine in the cerebral cortex. All aspects of the subject are covered, from its most elementary, at the molecular and cellular levels, to its systemic and holistic implications, including its role in cognition and involvement in human diseases and therapeutics. The twenty-two chapters are grouped under four main headings : I. Functional Morphology of the Acetylcholine Innervation in Cerebral Cortex (Including Hippocampus); II. Modes of Action of Acetylcholine in the Cerebral Cortex; III. Cortical Properties and Functions Modulated by Acetylcholine, and IV. Clinical, Pathological and Therapeutic Implications. This broad perspective updates the reader on recent advances and future trends in the study of a major neuromodulatory system in brain.
Book Synopsis The Roots of Visual Awareness by : C.A. Heywood
Download or read book The Roots of Visual Awareness written by C.A. Heywood and published by Elsevier. This book was released on 2003-10-31 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume was assembled in honor of Professor Alan Cowey FRS, and attempts to embrace his wide range of research interests in visual neuroscience. It is divided into four sections. The first contains a group of papers dealing with different fundamental aspects of the visual system, including the control and monitoring of eye movements. The second is concerned with the functional organization of cortical visual areas and their role in visual perception and visually guided action. The third addresses issues concerning color and motion perception, along with broader questions of visual attention; and the effects of selective brain damage on these different aspects of visual experience. The fourth and final section of the volume deals explicitly with questions relating to visual awareness, with particular emphasis on 'blindsight', a topic on which Alan Cowey has worked extensively in recent years, both in humans and in monkeys.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Gonadotropin-Releasing Hormone: Molecules and Receptors by : I.S. Parhar
Download or read book Gonadotropin-Releasing Hormone: Molecules and Receptors written by I.S. Parhar and published by Elsevier. This book was released on 2002-11-22 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes the evolution and physiology of GnRH molecules and receptors, and provides insight as to how social behavior influences cellular and molecular events in the brain from a comparative perspective. The chapters in this volume are divided into three major sections: Development and Cell Migration, GnRH Receptors, Physiology and Regulation. The review papers arose primarily from presentations made at the Second International Symposium on the Comparative Biology of GnRH, held in Penang, Malaysia, June 2-4, 2001; a satellite symposium in conjunction with the XIV International Congress of Comparative Endocrinology, Sorrento, Italy. In addition, leading neuroscientists doing cutting-edge research in the field of GnRH were invited as authors to make this volume a valuable reference.
