Neuron Glia Interactions Underlying Activity Dependent Plasticity In The Developing Visual System

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Neuron-glia Interactions Underlying Activity-dependent Plasticity in the Developing Visual System

Author : Zahraa Chorghay
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (129 download)

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Book Synopsis Neuron-glia Interactions Underlying Activity-dependent Plasticity in the Developing Visual System by : Zahraa Chorghay

Download or read book Neuron-glia Interactions Underlying Activity-dependent Plasticity in the Developing Visual System written by Zahraa Chorghay and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "A fundamental aspect of biological organisation is intercellular communication, which is necessary for the coordination and function of multicellular assemblies, and ultimately, for the survival of organisms in an everchanging environment. Within the developing nervous system, the different cell types - neuronal and glial - must work together for the formation, maintenance, and refinement of brain circuits. To further our understanding of activity-dependent circuit plasticity, two distinct phenomena of neuron-glia interactions in the developing visual system were investigated. First, the developmental progression of early myelin ensheathment in the Xenopus laevis was characterised. Based on this work, an appropriate developmental window was identified to investigate myelin plasticity, specifically, by examining the effects of early patterned sensory visual experience on myelin ensheathment in the Xenopus retinotectal circuit. We observed that patterned sensory experience evoking robust neuronal activity also increased early myelin ensheathment, whereas dampened neuronal activity reduced it. These findings thus lend support to the possibility of shared mechanisms for the control of timing-dependent plasticity and myelination during circuit development. In parallel, we explored the role of D-serine, which is a co-agonist of the N-methyl-D-aspartate glutamate receptor (NMDAR) and its availability is regulated by neuron-glia interactions. D-serine administration appears to prematurely stabilise the dendritic arbours and synapses of recently differentiating tectal neurons, though chronic exposure may also lead to functional compensation in overall synaptic density and visually evoked calcium responses in the optic tectum. Thus, the neuron-glia-dependent availability of D-serine at glutamatergic synapses may contribute to activity-dependent NMDAR-mediated refinement of the developing tectal circuit. By examining some of the neuron-glia interactions underlying activity-dependent plasticity, this dissertation aims to contribute to our understanding of the complex and dynamic processes necessary for biological systems to function optimally in their environment"--

Neural Plasticity and Memory

Author : Federico Bermudez-Rattoni
Publisher : CRC Press
ISBN 13 : 1420008412
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Neural Plasticity and Memory by : Federico Bermudez-Rattoni

Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq

From Neurons to Neighborhoods

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309069882
Total Pages : 610 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis From Neurons to Neighborhoods by : National Research Council

Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Homeostatic Synaptic Plasticity: From Synaptic Circuit Assembly to Neurological Disorders

Author : Lorenzo A. Cingolani
Publisher : Frontiers Media SA
ISBN 13 : 2889669882
Total Pages : 174 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Homeostatic Synaptic Plasticity: From Synaptic Circuit Assembly to Neurological Disorders by : Lorenzo A. Cingolani

Download or read book Homeostatic Synaptic Plasticity: From Synaptic Circuit Assembly to Neurological Disorders written by Lorenzo A. Cingolani and published by Frontiers Media SA. This book was released on 2021-07-08 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Mouse Nervous System

Author : Charles Watson
Publisher : Academic Press
ISBN 13 : 0123694973
Total Pages : 815 pages
Book Rating : 4.1/5 (236 download)

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Book Synopsis The Mouse Nervous System by : Charles Watson

Download or read book The Mouse Nervous System written by Charles Watson and published by Academic Press. This book was released on 2011-11-28 with total page 815 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience. Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases Examples of the use of mouse models in the study of neurological illness

Cognitive Enhancement in Schizophrenia and Related Disorders

Author : Matcheri Keshavan
Publisher : Cambridge University Press
ISBN 13 : 1107194784
Total Pages : 199 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Cognitive Enhancement in Schizophrenia and Related Disorders by : Matcheri Keshavan

Download or read book Cognitive Enhancement in Schizophrenia and Related Disorders written by Matcheri Keshavan and published by Cambridge University Press. This book was released on 2019-03-21 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide on how to assess and treat schizophrenia and related disorders using cognitive rehabilitation.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Associative Memory Cells: Basic Units of Memory Trace

Author : Jin-Hui Wang
Publisher : Springer Nature
ISBN 13 : 9811395012
Total Pages : 275 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Associative Memory Cells: Basic Units of Memory Trace by : Jin-Hui Wang

Download or read book Associative Memory Cells: Basic Units of Memory Trace written by Jin-Hui Wang and published by Springer Nature. This book was released on 2019-09-10 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on associative memory cells and their working principles, which can be applied to associative memories and memory-relevant cognitions. Providing comprehensive diagrams, it presents the author's personal perspectives on pathology and therapeutic strategies for memory deficits in patients suffering from neurological diseases and psychiatric disorders. Associative learning is a common approach to acquire multiple associated signals, including knowledge, experiences and skills from natural environments or social interaction. The identification of the cellular and molecular mechanisms underlying associative memory is important in furthering our understanding of the principles of memory formation and memory-relevant behaviors as well as in developing therapeutic strategies that enhance memory capacity in healthy individuals and improve memory deficit in patients suffering from neurological disease and psychiatric disorders. Although a series of hypotheses about neural substrates for associative memory has been proposed, numerous questions still need to be addressed, especially the basic units and their working principle in engrams and circuits specific for various memory patterns. This book summarizes the developments concerning associative memory cells reported in current and past literature, providing a valuable overview of the field for neuroscientists, psychologists and students.

Neurogenesis and Neural Plasticity

Author : Catherine Belzung
Publisher : Springer Science & Business Media
ISBN 13 : 364236232X
Total Pages : 447 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Neurogenesis and Neural Plasticity by : Catherine Belzung

Download or read book Neurogenesis and Neural Plasticity written by Catherine Belzung and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.

Structural and Functional Organization of the Synapse

Author : Johannes W. Hell
Publisher : Springer Science & Business Media
ISBN 13 : 0387772324
Total Pages : 801 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Structural and Functional Organization of the Synapse by : Johannes W. Hell

Download or read book Structural and Functional Organization of the Synapse written by Johannes W. Hell and published by Springer Science & Business Media. This book was released on 2008-06-25 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new Springer volume, which comes complete with a free DVD, is a comprehensive and detailed overview of the synapse with emphasis on the glutamatergic synapse. Most chapters relate the synapse’s functional aspects to its molecular mechanisms. This approach shows which mechanisms are characterized on both the functional and structural level and can thus be considered firmly established. It’s an important text for neuroscientists and disease-oriented clinicians in neurology.

The Hippocampus

Author : Ales Stuchlik
Publisher : BoD – Books on Demand
ISBN 13 : 1789233569
Total Pages : 180 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis The Hippocampus by : Ales Stuchlik

Download or read book The Hippocampus written by Ales Stuchlik and published by BoD – Books on Demand. This book was released on 2018-07-11 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is an important brain region, a true central hub for memory of various kinds and other processes. Neuropsychiatric disorders such as Alzheimer's disease, drug addiction, and schizophrenia are characterized by hippocampal alterations. The dentate gyrus of the hippocampus is a site exhibiting adult neurogenesis. This book covers the topic of the hippocampus from various perspectives. It discusses adult neurogenesis, effect of enriched environments on hippocampal plasticity, and long-term potentiation-associated gene expression. The book also addresses multiscale representations of complex environments and strategies in the hippocampus-dependent spatial tasks. Finally, insight into the hippocampus as a link between negative affect and relapse to psychostimulants is provided. The book collects evidence of various hippocampal functions in healthy and disordered brain.

Development of the Visual System

Author : Retina Research Foundation (U.S.). Symposium
Publisher : MIT Press
ISBN 13 : 9780262121545
Total Pages : 330 pages
Book Rating : 4.1/5 (215 download)

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Book Synopsis Development of the Visual System by : Retina Research Foundation (U.S.). Symposium

Download or read book Development of the Visual System written by Retina Research Foundation (U.S.). Symposium and published by MIT Press. This book was released on 1991 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of the Visual System presents a selection of current studies that clearly illustrate principles of visual system development. These range from retinal development in fish and frogs to the effects of abnormal visual experience on the primary visual cortex of the cat. The book is unique in addressing four specific and fundamental aspects of development: cell lineage and cell fate, specificity and targeting of axons, specification of visual cortex, and correlates of the critical period. Encompassing technical advances in cellular and molecular biology and in video imaging and microscopy, contributions in each of these areas provide new information at the cellular and molecular levels to complement the now classic descriptions of visual development previously available at the level of neural systems.ContributorsKaren L. Allendoerfer, David M. Altshuler, Antonella Antonini, Seymour Benzer, Edward M. Callaway, Constance L. Cepko, Hollis T. Cline, Max S. Cynader, N. W. Daw, Scott E. Fraser, K. Fox, Eckhard Friauf, Anirvan Ghosh, R. W. Guillery, William A. Harris, Christine E. Holt, Lawrence C. Katz, Susan McConnell, Pamela A. Raymond, Thomas A. Reh, Carla J. Shatz, Michael P. Stryker, Claudia A. 0. Stuermer, Mriganka Sur, David L. Turner, T. N. Wiesel

Brain Energy Metabolism

Author : Johannes Hirrlinger
Publisher : Humana Press
ISBN 13 : 9781493910588
Total Pages : 0 pages
Book Rating : 4.9/5 (15 download)

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Book Synopsis Brain Energy Metabolism by : Johannes Hirrlinger

Download or read book Brain Energy Metabolism written by Johannes Hirrlinger and published by Humana Press. This book was released on 2014-09-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Energy Metabolism addresses its challenging subject by presenting diverse technologies allowing for the investigation of brain energy metabolism on different levels of complexity. Model systems are discussed, starting from the reductionist approach like primary cell cultures which allow assessing of the properties and functions of a single brain cell type with many different types of analysis, however, at the expense of neglecting the interaction between cell types in the brain. On the other end, analysis in animals and humans in vivo is discussed, maintaining the full complexity of the tissue and the organism but making high demands on the methods of analysis. Written for the popular Neuromethods series, chapters include the kind of detailed description and key implementation advice that aims to support reproducible results in the lab. Meticulous and authoritative, Brain Energy Metabolism provides an ideal guide for researchers interested in brain energy metabolism with the hope of stimulating more research in this exciting and very important field.

Astrocytes in (Patho)Physiology of the Nervous System

Author : Vladimir Parpura
Publisher : Springer Science & Business Media
ISBN 13 : 0387794921
Total Pages : 701 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Astrocytes in (Patho)Physiology of the Nervous System by : Vladimir Parpura

Download or read book Astrocytes in (Patho)Physiology of the Nervous System written by Vladimir Parpura and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes were the original neuroglia that Ramón y Cajal visualized in 1913 using a gold sublimate stain. This stain targeted intermediate filaments that we now know consist mainly of glial fibrillary acidic protein, a protein used today as an astrocytic marker. Cajal described the morphological diversity of these cells with some ast- cytes surrounding neurons, while the others are intimately associated with vasculature. We start the book by discussing the heterogeneity of astrocytes using contemporary tools and by calling into question the assumption by classical neuroscience that neurons and glia are derived from distinct pools of progenitor cells. Astrocytes have long been neglected as active participants in intercellular communication and information processing in the central nervous system, in part due to their lack of electrical excitability. The follow up chapters review the “nuts and bolts” of ast- cytic physiology; astrocytes possess a diverse assortment of ion channels, neu- transmitter receptors, and transport mechanisms that enable the astrocytes to respond to many of the same signals that act on neurons. Since astrocytes can detect chemical transmitters that are released from neurons and can release their own extracellular signals there is an increasing awareness that they play physiological roles in regulating neuronal activity and synaptic transmission. In addition to these physiological roles, it is becoming increasingly recognized that astrocytes play critical roles during pathophysiological states of the nervous system; these states include gliomas, Alexander disease, and epilepsy to mention a few.

Jasper's Basic Mechanisms of the Epilepsies

Author : Jeffrey Noebels
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Webvision

Author : Helga Kolb
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (53 download)

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Book Synopsis Webvision by : Helga Kolb

Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Functional Brain Mapping: Methods and Aims

Author : Vassiliy Tsytsarev
Publisher : Springer Nature
ISBN 13 : 9811568839
Total Pages : 203 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Functional Brain Mapping: Methods and Aims by : Vassiliy Tsytsarev

Download or read book Functional Brain Mapping: Methods and Aims written by Vassiliy Tsytsarev and published by Springer Nature. This book was released on 2020-09-07 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an essential overview of the broad range of functional brain imaging techniques, as well as neuroscientific methods suitable for various scientific tasks in fundamental and clinical neuroscience. It also shares information on novel methods in computational neuroscience, mathematical algorithms, image processing, and applications to neuroscience. The mammalian brain is a huge and complex network that consists of billions of neural and glial cells. Decoding how information is represented and processed by this neural network requires the ability to monitor the dynamics of large numbers of neurons at high temporal and spatial resolution over a large part of the brain. Functional brain optical imaging has seen more than thirty years of intensive development. Current light-using methods provide good sensitivity to functional changes through intrinsic contrast and are rapidly exploiting the growing availability of exogenous fluorescence probes. In addition, various types of functional brain optical imaging are now being used to reveal the brain’s microanatomy and physiology.