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Author : G. a. Qureshi
Publisher : VSP
ISBN 13 : 9789067642774
Total Pages : 880 pages
Book Rating : 4.6/5 (427 download)
Download or read book Neurochemical Markers of Degenerative Nervous Diseases and Drug Addiction written by G. a. Qureshi and published by VSP. This book was released on 1998-03 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Bertha Madras
Publisher : Elsevier
ISBN 13 : 0124186858
Total Pages : 625 pages
Book Rating : 4.1/5 (241 download)
Download or read book The Effects of Drug Abuse on the Human Nervous System written by Bertha Madras and published by Elsevier. This book was released on 2013-11-15 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. A comprehensive reference on the effects of drug addiction on the human nervous system Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs Includes foundational science chapters on the biology of addiction Details challenges in diagnosis and treatment options
Author : Jonas H. Ellenberg
Publisher : CRC Press
ISBN 13 : 9780824788230
Total Pages : 600 pages
Book Rating : 4.7/5 (882 download)
Download or read book Etiology of Parkinson's Disease written by Jonas H. Ellenberg and published by CRC Press. This book was released on 1995-03-01 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.
Author : R.J. Castellani
Publisher : IOS Press
ISBN 13 : 164368065X
Total Pages : 506 pages
Book Rating : 4.6/5 (436 download)
Download or read book Handbook of Traumatic Brain Injury and Neurodegeneration written by R.J. Castellani and published by IOS Press. This book was released on 2020-04-24 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holbourne’s theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood ‘punch drunk’ syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field.
Author : Kenneth Hensley
Publisher : Springer Science & Business Media
ISBN 13 : 1592594247
Total Pages : 212 pages
Book Rating : 4.5/5 (925 download)
Download or read book Methods in Biological Oxidative Stress written by Kenneth Hensley and published by Springer Science & Business Media. This book was released on 2008-02-06 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative damage appears to play a central role in the development of a wide range of tissue pathology, including neurodegenerative disease, drug side-effects, xenobiotic toxicity, carcinogenesis, and the aging process, to name just a few. Because of the centrality of oxidative processes to normal and abnormal tissue function, it has become imperative to develop appropriate analytical techniques to facilitate the quantitation of significant reactants. Without advances in methodology, corresponding advances in our knowledge of underlying biochemical events will be necessarily limited. Drs. Hensley and Floyd have done an outstanding job of assembling the work of world-class experts into Methods in Biological Oxidative Stress. The contributors have presented concise, yet thorough, descriptions of the state-of-the-art methods that any investigator working in the field needs to access. Mannfred A. Hollinger v Preface Free radicals and reactive oxidizing agents were once ignored as biochemical entities not worth close scrutiny, but are now recognized as causes or contributing factors in dozens, if not hundreds, of disease states. In addition, free radical metabolisms of xenobiotics have become increasingly important to pharmacologists. Accordingly, the need has arisen to accurately quantify reactive oxygen species and their byproducts. Methods in Biological Oxidative Stress is practical in scope, providing the details of up-to-date techniques for measuring oxidative stress and detecting oxidizing agents both in vitro and in vivo. The contributors are recognized experts in the field of oxidative stress who have developed novel strategies for studying biological oxidations.
Author : Richard G. Cutler
Publisher : World Scientific
ISBN 13 : 9812775730
Total Pages : 872 pages
Book Rating : 4.8/5 (127 download)
Download or read book Critical Reviews of Oxidative Stress and Aging written by Richard G. Cutler and published by World Scientific. This book was released on 2003 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.
Author : Roger Bertolotti
Publisher : VSP
ISBN 13 : 9789067643283
Total Pages : 576 pages
Book Rating : 4.6/5 (432 download)
Download or read book Progress in Gene Therapy written by Roger Bertolotti and published by VSP. This book was released on 2000-09-28 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene Therapy is expected to revolutionize the practice of medicine at the turn of the third Millennium. Therapeutic/prophylactic benefits should arise from both gene transfer and gene repair/inactivation protocols devised for patient's somatic cells. Gene expression cassettes, designed for the production of therapeutic proteins and non-coding RNA, are thus experimented together with emerging gene repair/inactivation techniques on a variety of inherited, acquired and infectious/parasitic diseases, including complex neuro-degenerative processes. This book presents a collection of chapters on the main aspects of Gene Therapy, some of which have already been treated in the past, and updates and further develops the current survey. It is aimed at understanding why Human Gene Therapy is likely to be a medical breakthrough, although definitive clinical success still needs time to accomplish. The contributions focus on both technical/biomedical concepts and on experimental/clinical data that appear to confer potential universality to Gene Therapy. This book does not claim to provide an exhaustive review of the pathologies, which are currently approached with Gene Therapy. The presentation of current and emerging approaches, together with problems and tentative issues aims to serve as a booster for the development of new applications in every field of medicine and will, therefore, be of value and interest to researchers in this exciting field.
Author : P. M. Frossard
Publisher : VSP
ISBN 13 : 9789067643115
Total Pages : 284 pages
Book Rating : 4.6/5 (431 download)
Download or read book Genetic, Immune and Molecular Predisposition to Hypertension written by P. M. Frossard and published by VSP. This book was released on 1999-01-01 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Catherine Collin
Publisher : CRC Press
ISBN 13 : 9067644129
Total Pages : 876 pages
Book Rating : 4.0/5 (676 download)
Download or read book Advances in Neuroregulation and Neuroprotection written by Catherine Collin and published by CRC Press. This book was released on 2005-04-15 with total page 876 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroregulation is a challenging and rapidly developing field that holds the key to many currently intractable medical conditions from nervous and mental diseases to stress-related disorders. Advances in Neuroregulation mirrors the broad scope of research in this area with topics ranging from new concepts on the immune system and on the action of antidepressants to the evolution and development of the autonomic nervous system. In addition, the latest research findings are presented for behavioural disorders and medical conditions such as Parkinson’s disease, Alzheimer’s disease, epilepsy and attention-deficit/hyperactivity disorder. Another area of emphasis is the body's responses to stress and the effect of neuroactive agents in the treatment of stress-related conditions. Many chapters are devoted to the progress being made at the cellular and molecular level, including areas such as: - the conditions for culture of different types of neural cells - conformational diseases and the protein folding problem - vasoactive intestinal polypeptide release from pancreatic islets - the effect of melatonin and corticosterone on macrophages Here, in a book that expands the frontiers of neuroscience, researchers into neuroregulation at the molecular and cellular levels as well as those working at the clinical and systemic levels will find important results relating to their field.
Author : G. Ali Qureshi
Publisher : Elsevier
ISBN 13 : 0080489494
Total Pages : 795 pages
Book Rating : 4.0/5 (84 download)
Download or read book Oxidative Stress and Neurodegenerative Disorders written by G. Ali Qureshi and published by Elsevier. This book was released on 2007-03-22 with total page 795 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders. * Contains the latest information on the subject of neurodegenerative disorders* Reflects on various factors involved in degeneration and gives suggestions for how to tackle these problems
Author : Gerald Huether
Publisher : Springer Science & Business Media
ISBN 13 : 1461547091
Total Pages : 824 pages
Book Rating : 4.4/5 (615 download)
Download or read book Tryptophan, Serotonin, and Melatonin written by Gerald Huether and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the Ninth Meeting of the "International Study Group for Tryptophan Research" (lSTRY), held at the University of Hamburg, Germany, from October 10 to 14, 1998. At this meeting the recent developments in the field of tryptophan research were presented by leading researchers from all over the world in 81 oral and 48 poster contri butions. Research on tryptophan and its derivatives provides an inexhaustible subject. At the conference we tried to compose a multifacetted picture of the recent investiga tions through contributions from the major disciplines involved. Thus, we tried to strike a balance between basic research topics and clinical, nutritional or industrial applica tions. We offered workshops on tryptophan (in sleep and mood), melatonjn, IDO-acti vation and the eosinophilia-myalgia syndrome (EMS) as a platform for intensive discussion for the participants. In these proceedings many contributions are multidisciplinary and have practical or theoretical implications for different research fields. Hence, we have organized this volume in nine main chapters according to basic disciplines and subjects. We are aware that this classification is artificial, but we hope that it is the best compromise for contributors and readers.
Author : B. Sperner
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 380557262X
Total Pages : 149 pages
Book Rating : 4.8/5 (55 download)
Download or read book Psychoneuroimmunology written by B. Sperner and published by Karger Medical and Scientific Publishers. This book was released on 2001-01-01 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication offers cutting-edge information about basic neurochemical and neuroimmunological research as well as clinical studies of immunological disarrangements and immunological dysfunctions in psychiatric disorders. Psychiatrists and immunologists in the clinic, and researchers in basic sciences will also find this book essential reading. Likewise, it will be relevant to graduate and undergraduate students with a special interest in the neurobiology of psychiatric disorders.'
Author : Barbara H. Herman
Publisher : Springer Science & Business Media
ISBN 13 : 1592593062
Total Pages : 437 pages
Book Rating : 4.5/5 (925 download)
Download or read book Glutamate and Addiction written by Barbara H. Herman and published by Springer Science & Business Media. This book was released on 2002-08-22 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Glutamate and Addiction, world-renowned scientific experts critically review all of the evidence for the role of glutamatergic systems in opiate, stimulant, and alcohol addiction. Using a variety of pharmacological, biochemical, genetic, and brain imaging techniques, these investigators show precisely how glutamate affects such addictions and how modifying certain elements of the glutamatergic system appear to alleviate particular components of addiction. Their survey takes in both clinical approaches using medications that influence glutamate and cutting-edge preclinical approaches that manipulate specific subtypes of glutamate receptors or specific substrates of the "glutamate cascade" to determine their roles in various addictive states.
Author : Edgar Garcia-Rill
Publisher : Academic Press
ISBN 13 : 0128179937
Total Pages : 276 pages
Book Rating : 4.1/5 (281 download)
Download or read book Arousal in Neurological and Psychiatric Diseases written by Edgar Garcia-Rill and published by Academic Press. This book was released on 2019-06-18 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arousal in Neurological and Psychiatric Diseases focuses on the dysregulation of arousal found in many neurological and psychiatric disorders. Chapters describe the physiology of each process, how it presents in each disorder, and the most appropriate treatment(s). The book also imparts the understanding of the RAS as a system that not only modulates waking, but also survival mechanisms, such as fight vs. flight responses and other reflexes. This book helps neuroscientists, sleep researchers, neurologists and psychiatrists understand the basic mechanisms that modulate arousal in health and disease. In addition, it promotes therapies that can alter the severity and manifestation of multiple disorders. Provides a comprehensive overview of the basic mechanisms behind dysregulation of arousal in neurological and psychiatric disorders Describes, in detail, the function of the Reticular Activating System with respect to higher functions, motor control and the intertwining of arousal and motor disorders Covers multiple neurological disorders, including epilepsy, Alzheimer’s disease, Parkinson’s disease and autism
Author : David G. Lichter
Publisher : Guilford Press
ISBN 13 : 9781572306233
Total Pages : 474 pages
Book Rating : 4.3/5 (62 download)
Download or read book Frontal-subcortical Circuits in Psychiatric and Neurological Disorders written by David G. Lichter and published by Guilford Press. This book was released on 2001-01-01 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors review knowledge on the anatomy of the frontal-subcortical circuits, their connections to other brain regions, and their influences on motor, cognitive, affective, and behavioral functioning. Specific clinical problems are addressed, including Parkinson's disease, obsessive/compulsive disorder, ADHD, and more. of full-color illustrations.
Author : Andreas Büttner
Publisher : Springer Nature
ISBN 13 : 3030605310
Total Pages : 116 pages
Book Rating : 4.0/5 (36 download)
Download or read book Neuropathology of Drug Abuse written by Andreas Büttner and published by Springer Nature. This book was released on 2020-10-27 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the current state of knowledge concerning neuropathologies resulting from drug abuse. The first chapters offer readers detailed information on the neurobiological basics of drug abuse and the results of neuroimaging studies in drug abusers. The focus of the book is on neuropathological findings in drug abusers for the predominant substances, which include cannabis, opiates, cocaine, amphetamine, methamphetamine and a broad spectrum of designer drugs. These findings are supported by histological illustrations and discussed in connection with recent scientific publications. A chapter specifically addressing clinicians is also included, and highlights the implications for further therapy. The book is essential reading for neuropathologists, neurologists, neuroradiologists and psychiatrists, as well as other health professionals and scientists interested and engaged in the problem of drug abuse. Although a great deal of data has been derived from animal models and from human neuroimaging studies, little is known about the morphological effects of drug abuse on the human brain. In recent years, fundamental drug-induced effects on the cellular elements of the brain have been detected. These alterations might not only be the substrate of the neuroimaging data but might also have implications for clinical research and therapy. In addition, drug abuse may induce premature neurodegeneration.
Author : Office of the Surgeon General
Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781974580620
Total Pages : 420 pages
Book Rating : 4.5/5 (86 download)
Download or read book Facing Addiction in America written by Office of the Surgeon General and published by Createspace Independent Publishing Platform. This book was released on 2017-08-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences.
