National Cancer Institute Vol 3

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Clinical Trials in Oncology, Third Edition

Author : Stephanie Green
Publisher : CRC Press
ISBN 13 : 1439814481
Total Pages : 266 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Clinical Trials in Oncology, Third Edition by : Stephanie Green

Download or read book Clinical Trials in Oncology, Third Edition written by Stephanie Green and published by CRC Press. This book was released on 2012-05-09 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data. Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.

Implementation Science at a Glance

Author : National Cancer Institute (U.S.)
Publisher : Government Printing Office
ISBN 13 : 0160950694
Total Pages : 47 pages
Book Rating : 4.1/5 (69 download)

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Book Synopsis Implementation Science at a Glance by : National Cancer Institute (U.S.)

Download or read book Implementation Science at a Glance written by National Cancer Institute (U.S.) and published by Government Printing Office. This book was released on 2019-04-01 with total page 47 pages. Available in PDF, EPUB and Kindle. Book excerpt: While many effective interventions can reduce cancer risk, incidence, and death, as well as enhance quality of life, they are of no benefit if they cannot be delivered to those in need. In the face of increasingly dynamic and resource-constrained conditions, implementation science plays a critical role in delivering cancer control practices. This 30-page workbook was written by members of the NCI (National Cancer Institute) implementation Science team and reviewed by nearly 100 public health practitioners and implementation science researchers. Through summaries of key theories, methods, and models, the guide shows how greater use of implementation science can support the effective adoption of evidence-based interventions. Case studies illustrate how practitioners are successfully applying implementation science in their cancer control programs

Reducing Environmental Cancer Risk

Author : Suzanne H. Reuben
Publisher : DIANE Publishing
ISBN 13 : 1437934218
Total Pages : 240 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Reducing Environmental Cancer Risk by : Suzanne H. Reuben

Download or read book Reducing Environmental Cancer Risk written by Suzanne H. Reuben and published by DIANE Publishing. This book was released on 2010-10 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.

Fulfilling the Potential of Cancer Prevention and Early Detection

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309170133
Total Pages : 564 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Fulfilling the Potential of Cancer Prevention and Early Detection by : National Research Council

Download or read book Fulfilling the Potential of Cancer Prevention and Early Detection written by National Research Council and published by National Academies Press. This book was released on 2003-05-07 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer ranks second only to heart disease as a leading cause of death in the United States, making it a tremendous burden in years of life lost, patient suffering, and economic costs. Fulfilling the Potential for Cancer Prevention and Early Detection reviews the proof that we can dramatically reduce cancer rates. The National Cancer Policy Board, part of the Institute of Medicine, outlines a national strategy to realize the promise of cancer prevention and early detection, including specific and wide-ranging recommendations. Offering a wealth of information and directly addressing major controversies, the book includes: A detailed look at how significantly cancer could be reduced through lifestyle changes, evaluating approaches used to alter eating, smoking, and exercise habits. An analysis of the intuitive notion that screening for cancer leads to improved health outcomes, including a discussion of screening methods, potential risks, and current recommendations. An examination of cancer prevention and control opportunities in primary health care delivery settings, including a review of interventions aimed at improving provider performance. Reviews of professional education and training programs, research trends and opportunities, and federal programs that support cancer prevention and early detection. This in-depth volume will be of interest to policy analysts, cancer and public health specialists, health care administrators and providers, researchers, insurers, medical journalists, and patient advocates.

Cancer Control Opportunities in Low- and Middle-Income Countries

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030913398X
Total Pages : 340 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cancer Control Opportunities in Low- and Middle-Income Countries by : Institute of Medicine

Download or read book Cancer Control Opportunities in Low- and Middle-Income Countries written by Institute of Medicine and published by National Academies Press. This book was released on 2007-01-26 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is low or absent on the health agendas of low- and middle-income countries (LMCs) despite the fact that more people die from cancer in these countries than from AIDS and malaria combined. International health organizations, bilateral aid agencies, and major foundations—which are instrumental in setting health priorities—also have largely ignored cancer in these countries. This book identifies feasible, affordable steps for LMCs and their international partners to begin to reduce the cancer burden for current and future generations. Stemming the growth of cigarette smoking tops the list to prevent cancer and all the other major chronic diseases. Other priorities include infant vaccination against the hepatitis B virus to prevent liver cancers and vaccination to prevent cervical cancer. Developing and increasing capacity for cancer screening and treatment of highly curable cancers (including most childhood malignancies) can be accomplished using "resource-level appropriateness" as a guide. And there are ways to make inexpensive oral morphine available to ease the pain of the many who will still die from cancer.

Screening

Author : Angela E. Raffle
Publisher : Oxford University Press
ISBN 13 : 0192528661
Total Pages : 368 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Screening by : Angela E. Raffle

Download or read book Screening written by Angela E. Raffle and published by Oxford University Press. This book was released on 2019-06-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Screening programmes involve the systematic offer of testing for populations or groups of apparently healthy people to identify individuals who may be at future risk of a particular medical condition or disease, with the aim of offering intervention to reduce their risk. For many years, screening was practised without debate, and without evidence, but in the 1960s serious challenges were raised about many of the screening procedures then being practised. Benefits and harms of screening must be measured in high quality trials, and the benefits of screening must be weighed alongside the negative side-effects. Concerns were raised about potential and actual harm arising when people without a health problem received dangerous and unnecessary investigations and treatments as a result of routine screening tests. Controversy raged, and it took some 50 years to achieve widespread recognition that evidence-based and quality assured programme delivery was essential, coupled with provision of balanced informed to enable informed choice for potential participants. Commercially motivated provision of poor quality and non-evidence based screening tests is increasing and screening remains a highly contested topic that has relevance in all health systems including for the general public and media. This book serves as a practical and comprehensive guide to all aspects of screening. Following the international success of the first edition, this second edition brings extensive updates and new case study material. The first section deals with concepts, methods, and evidence, charts the story of screening back to 1861, and covers all aspects of a screening programme and how to research the full consequences. The second section is a practical guide to sound policy-making and to high quality delivery of best value screening. The controversies, paradoxes, uncertainties, and ethical dilemmas of screening are explained, and each chapter is packed with examples, real-life case histories, helpful summary points, and self-test questions. Reference is made to the NHS, a leader in screening, but the primary focus is on universal principles, making the book highly relevant across the globe.

Journal of the National Cancer Institute

Author :
Publisher :
ISBN 13 :
Total Pages : 950 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Journal of the National Cancer Institute by :

Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2006 with total page 950 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Reprints from Postdoctoral and Special Fellows of the National Cancer Institute, July 1967-December 1970

Author : National Cancer Institute (U.S.)
Publisher :
ISBN 13 :
Total Pages : 76 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Reprints from Postdoctoral and Special Fellows of the National Cancer Institute, July 1967-December 1970 by : National Cancer Institute (U.S.)

Download or read book Reprints from Postdoctoral and Special Fellows of the National Cancer Institute, July 1967-December 1970 written by National Cancer Institute (U.S.) and published by . This book was released on 1971 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Scientific Information Services of the National Cancer Institute

Author : National Institutes of Health (U.S.)
Publisher :
ISBN 13 :
Total Pages : 40 pages
Book Rating : 4.:/5 (2 download)

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Book Synopsis Scientific Information Services of the National Cancer Institute by : National Institutes of Health (U.S.)

Download or read book Scientific Information Services of the National Cancer Institute written by National Institutes of Health (U.S.) and published by . This book was released on 1987 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anticancer Drug Development Guide

Author : Beverly A. Teicher
Publisher : Springer Science & Business Media
ISBN 13 : 1592597394
Total Pages : 514 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Anticancer Drug Development Guide by : Beverly A. Teicher

Download or read book Anticancer Drug Development Guide written by Beverly A. Teicher and published by Springer Science & Business Media. This book was released on 2004-02-01 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique volume traces the critically important pathway by which a "molecule" becomes an "anticancer agent. " The recognition following World War I that the administration of toxic chemicals such as nitrogen mustards in a controlled manner could shrink malignant tumor masses for relatively substantial periods of time gave great impetus to the search for molecules that would be lethal to specific cancer cells. Weare still actively engaged in that search today. The question is how to discover these "anticancer" molecules. Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and Approval, Second Edition describes the evolution to the present of preclinical screening methods. The National Cancer Institute's high-throughput, in vitro disease-specific screen with 60 or more human tumor cell lines is used to search for molecules with novel mechanisms of action or activity against specific phenotypes. The Human Tumor Colony-Forming Assay (HTCA) uses fresh tumor biopsies as sources of cells that more nearly resemble the human disease. There is no doubt that the greatest successes of traditional chemotherapy have been in the leukemias and lymphomas. Since the earliest widely used in vivo drug screening models were the murine L 1210 and P388 leukemias, the community came to assume that these murine tumor models were appropriate to the discovery of "antileukemia" agents, but that other tumor models would be needed to discover drugs active against solid tumors.

Encyclopedia of Cancer

Author : Manfred Schwab
Publisher : Springer Science & Business Media
ISBN 13 : 3540368477
Total Pages : 3307 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Encyclopedia of Cancer by : Manfred Schwab

Download or read book Encyclopedia of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 3307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.

NIH Guide for Grants and Contracts

Author :
Publisher :
ISBN 13 :
Total Pages : 600 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis NIH Guide for Grants and Contracts by :

Download or read book NIH Guide for Grants and Contracts written by and published by . This book was released on 1976 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Children With Cancer

Author : Jeanne Munn Bracken
Publisher : Oxford University Press
ISBN 13 : 0199774226
Total Pages : 586 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Children With Cancer by : Jeanne Munn Bracken

Download or read book Children With Cancer written by Jeanne Munn Bracken and published by Oxford University Press. This book was released on 2010-07-06 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children can and do survive cancer; the last decade has seen many major advancements in treatment. Written honestly, yet in a reassuring tone, by a reference librarian whose child has survived cancer, Children with Cancer draws together a wealth of up-to-date information essential for anyone who wishes to help a child or family through this ordeal--including relatives, friends, teachers, and clergymen, as well as doctors, nurses, and other health care professionals. The information ranges from sophisticated, hard-to-find medical facts to practical tips on how to handle side effects, and much more. Describing in detail the whole range of childhood cancers, Bracken explores how they affect the child, the treatments available, how to cope with the changes this diagnosis will bring to the entire family, and where to go for both medical and emotional help. It also includes an appendix of common medical tests, a glossary of terms, and comprehensive lists of organizations, clinics, and cancer centers, complete with names and addresses. Reviews of the previous edition: "A remarkable job....The technical information is clearly stated, up to date and accurate.....But most of all, this is a human book."--Los Angeles Times "Comprehensive, well written, accurate, and compassionate.... Bracken's book can serve as a primary reference for parents and can be used as well by health care professionals and teachers." --Science Books and Films

Scientific Information Services of the National Cancer Institute

Author : National Cancer Institute (U.S.)
Publisher :
ISBN 13 :
Total Pages : 40 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Scientific Information Services of the National Cancer Institute by : National Cancer Institute (U.S.)

Download or read book Scientific Information Services of the National Cancer Institute written by National Cancer Institute (U.S.) and published by . This book was released on 1987 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Registration

Author : Ole Møller Jensen
Publisher : IARC
ISBN 13 : 9283211952
Total Pages : 295 pages
Book Rating : 4.2/5 (832 download)

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Book Synopsis Cancer Registration by : Ole Møller Jensen

Download or read book Cancer Registration written by Ole Møller Jensen and published by IARC. This book was released on 1991 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data obtained by population based cancer registries have a pivotal role in cancer control. Now also available in Spanish and French, this volume, which contains 15 authored chapters and four useful appendices, remains a standard reference for those planning to establish new cancer registries and those keen to adopt recognized methodologies. Information is given on the techniques required to collect, store, analyse and interpret data.

Anticancer Drug Development Guide

Author : Beverly A. Teicher
Publisher : Springer Science & Business Media
ISBN 13 : 1461581524
Total Pages : 315 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Anticancer Drug Development Guide by : Beverly A. Teicher

Download or read book Anticancer Drug Development Guide written by Beverly A. Teicher and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experienced cancer researchers from pharmaceutical companies, government laboratories, and academia comprehensively review and describe the arduous process of cancer drug discovery and approval. They focus on using preclinical in vivo and in vitro methods to identify molecules of interest, detailing the targets and criteria for success in each type of testing and defining the value of the information obtained from the various tests. They also define each stage of clinical testing, explain the criteria for success, and outline the requirements for FDA approval. A companion volume by the same editor (Cancer Therapeutics: Experimental and Clinical Agents) reviews existing anticancer drugs and potential anticancer therapies. These two volumes in the Cancer Drug Discovery and Development series reveal how and why molecules become anticancer drugs and thus offer a blueprint for the present and the future of the field.

Advancing the Science of Implementation Across the Cancer Continuum

Author : David A. Chambers (DPhil)
Publisher :
ISBN 13 : 0190647426
Total Pages : 441 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Advancing the Science of Implementation Across the Cancer Continuum by : David A. Chambers (DPhil)

Download or read book Advancing the Science of Implementation Across the Cancer Continuum written by David A. Chambers (DPhil) and published by . This book was released on 2018 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: While many effective interventions have been developed with the potential to significantly reduce morbidity and mortality from cancer, they are of no benefit to the health of populations if they cannot be delivered. In response to this challenge, Advancing the Science of Implementation across the Cancer Continuum provides an overview of research that can improve the delivery of evidence-based interventions in cancer prevention, early detection, treatment, and survivorship. Chapters explore the field of implementation science and its application to practice, a broad synthesis of relevant research and case studies illustrating each cancer-focused topic area, and emerging issues at the intersection of research and practice in cancer. Both comprehensive and accessible, this book is an ideal resource for researchers, clinical and public health practitioners, medical and public health students, and health policymakers.