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Myocardial Ischemia And Lipid Metabolism
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Book Synopsis Myocardial Ischemia and Lipid Metabolism by : R. Ferrari
Download or read book Myocardial Ischemia and Lipid Metabolism written by R. Ferrari and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past years, the thrust of research in cardiology has been toward an understanding of the engineering of the heart as a pump that transports blood to the various organs of the body. More recently, the fields of biochemistry and biophysics have come to influence heart research. The modern cardiologist can no longer pretend to understand, for example, what is happening to the patient with myocardial infarction or ischemia without understanding the principles of molecular biology. The structure and function of the heart are therefore central themes of cardiological research and practice, which incorporate knowledge and discoveries from diverse disciplines. The importance of lipid metabolism in the myocardium has become clearly understood. In the well-oxygenated heart, fatty acids are the preferred substrates. The fact that the heart derives most of its energy from the oxidation of lipids, which represent the larg est energy store of the body, is logical for an organ that must work throughout our lifetime. There are, however, several lines of evidence that during ischemia, lipids may. be harmful to the heart. High levels of free fatty acids in the serum have been suggested to play a role in causing life-threatening arryhthmias and damage in the ischemic heart. The molecular basis for these effects remains poorly understood, and several possible mechanisms for these harm ful effects have been suggested.
Book Synopsis Lipid metabolism in the normoxic and ischaemic heart by : H. Stam
Download or read book Lipid metabolism in the normoxic and ischaemic heart written by H. Stam and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific progress with respect to the important role of various lipids in myocardial function and the dearrangements of lipid metabolism underlying ischaemic heart disease(s) has been con siderable in recent years. In 1986 alone, an overall number ofl 044 full papers covering the topics "Lipids-Heart-Heart Disease", have been published in a variety of biochemistry, physiology, pharmacology and cardiology journals (source: Index Medicus). They have broadened our in sight into the molecular basis of myocardial lipidology and the lipido-chemical basis of car diology in health and disease, and have narrowed the gap between promising pharmacological intervention in experimental animals and clinical treatment of patients suffering from an ischaemic heart. Furthermore, they illustrate the fundamental significance of the product of the union between basic and clinical science. The rapid development of knowledge in the "Lipids-Heart-Heart Disease" triad prompted us to organize the International Symposium on Lipid Metabolism in the Normoxic and lschaemic Heart, held in Rotterdam (The Netherlands) on September 22 and 23, 1986. This meeting was a coproject of the Department of Biochemistry I (Medical Faculty, Erasmus University Rotter dam) and the Department of Physiology (Medical Faculty, University of Limburg) and was held under the auspices of the GerritJan Mulder Foundation (named after a famous Rotterdam physi cian and chemist who lived from 1802-1880) whom we thank for their co-operation. The present volume is a compendium of invited papers and contributions selected from the posters presented during the symposium.
Book Synopsis Advances in Nutritional Research by : H. Draper
Download or read book Advances in Nutritional Research written by H. Draper and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third volume of Advances in Nutritional Research continues the precedent set in previous volumes of providing authoritative reviews on the current state of knowledge with respect to major topics of ongoing nutritional research. This series is designed to be of value to investigators engaged in fundamental research as well as to those involved in its application to problems in human and animal nutrition. This volume contains three chapters on recent developments in research on inorganic elements, including a review, by F. H. Nielsen, of the evidence for a requirement for additional trace elements; a conspectus, by C. E. Casey and K. M. Hambidge, on the occurrence of trace element deficiencies in man; and a description, by M. Janghorbani and V. R. Young, of new methods of assessing the bioavailability of minerals in the diet. There are also three chapters on current topics of lipid research. One (by F. D. Sauer) is devoted to the cardiopathic effects of certain dietary monoenoic fatty acids, another (by C. Galli) to the influence of diet on prostaglandin synthesis, and the third (by H. 0. Bang and J. Dyerberg) to an analysis of the role of the unusual polyunsaturated fatty acids found in marine oils in the prevention of ischemic heart disease.
Book Synopsis Lipid Metabolism in Normoxic and Ischemic Heart by : Ger J. van der Vusse
Download or read book Lipid Metabolism in Normoxic and Ischemic Heart written by Ger J. van der Vusse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: During recent decades, bewildering progress has occurred in the field of Molecular and Cellular Biochemistry. Progress has been extraordinarily rapid primarily because of the challenge for finding solutions to a wide variety of diseases and the availability of new techniques for monitoring biochemical processes. This has resulted in a voluminous and complex literature in the field of biochemical medicine so that there is a clear need for the synthesis and analysis of the continuing expansion of valuable data. It was thus considered appropriate to initiate a new series of monographs, each dedicated to a specialized area of investigation, encompassing molecular and cellular processes in health and disease. Most of the biochemical scientists have devoted their energies in understanding the fundamentals of biochemistry and indeed impressive advances have been made in the past. However, the full potential for explanation has been hampered by the concept of universality of biochemical reactions occurring in the cell. In view of the fact that each organ in the body performs a distinct function, it is now beginning to be realized that each cell type is unique in its need to survive and perform its specific function. Accordingly, the aspect of individualty is receiving increased attention for revealing new avenues in the study of pathophysiology of cellular abnormalities.
Book Synopsis Lipid Metabolism in the Healthy and Disease Heart by : Ger J. van der Vusse
Download or read book Lipid Metabolism in the Healthy and Disease Heart written by Ger J. van der Vusse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Third International Symposium on Lipid Metabolism in the Normoxic and Ischemic Heart, September 9 & 10, 1991, Rotterdam, The Netherlands
Book Synopsis Lipid Metabolism in the Normoxic and Ischaemic Heart by : H. Stam
Download or read book Lipid Metabolism in the Normoxic and Ischaemic Heart written by H. Stam and published by Springer Verlag. This book was released on 1987 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Diet, Lipid Metabolism, and Atherosclerosis by : National Heart Institute (U.S.)
Download or read book Diet, Lipid Metabolism, and Atherosclerosis written by National Heart Institute (U.S.) and published by . This book was released on 1965 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Diet, Lipid Metabolism, and Atherosclerosis, a Review of Research Grants Supported by the National Heart Institute, 1958-1964 by : National Institutes of Health (U.S.)
Download or read book Diet, Lipid Metabolism, and Atherosclerosis, a Review of Research Grants Supported by the National Heart Institute, 1958-1964 written by National Institutes of Health (U.S.) and published by . This book was released on 1965 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lipid Metabolism and Health by : Robert J. Moffatt
Download or read book Lipid Metabolism and Health written by Robert J. Moffatt and published by CRC Press. This book was released on 2005-12-15 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: That a relation exists between lipids/lipoproteins and coronary artery disease is no longer an arguable point. However, the complexities associated with this relationship, and the number of factors that can impact and alter circumstances and clinical status, are many and diverse. Consequently, this relationship continues to receive a great deal of
Book Synopsis Cardiac Lipid Storage and Metabolism Following Myocardial Ischemia by :
Download or read book Cardiac Lipid Storage and Metabolism Following Myocardial Ischemia written by and published by . This book was released on 2015 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Myocardial Metabolism by : V. N. Smirnov
Download or read book Myocardial Metabolism written by V. N. Smirnov and published by CRC Press. This book was released on 1987 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lipid Metabolism and Its Pathology by : M. Halpern
Download or read book Lipid Metabolism and Its Pathology written by M. Halpern and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Emerging Role of Lipids in Metabolism and Disease by : Marco Segatto
Download or read book Emerging Role of Lipids in Metabolism and Disease written by Marco Segatto and published by MDPI. This book was released on 2021-04-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even though initially considered as a passive means for storing energy, lipids are now regarded as multifaceted molecules with crucial structural and functional activities. For instance, some of them play essential roles as key components of cell membranes whereas others act as signaling molecules in the regulation of cell homeostasis. In recent years, lipid research has attracted increasing interest because of the involvement of this class of compounds in human health. Indeed, a plethora of pathological conditions are characterized by alterations in lipid metabolism, such as cardiovascular diseases and brain disorders. This Special Issue is a collection of papers from different experts in lipid research, with the aim of providing new insights into the physiopathological involvement of lipids and their impact on human health. This collection also demonstrates the usefulness of interdisciplinary approaches in the development of novel methods to study and manipulate lipid metabolism, which may represent an attractive target for designing effective therapeutic strategies to counteract numerous pathologies.
Book Synopsis Drugs Affecting Lipid Metabolism by : Antonio M. Gotto
Download or read book Drugs Affecting Lipid Metabolism written by Antonio M. Gotto and published by Springer. This book was released on 1996-08-31 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even a brief scan of the table of contents of the present volume is enough to disclose the diversity of research interests and opinions in the field of lipidology. It is precisely this diversity that is the strength of our field and that was showcased by the XII International Symposium of DRUGS AFFECTING LIPID METABOLISM (DALM). The papers published here from these proceedings may be divided into three categories: those that define-and refine---our understanding ofthe clinical benefit of aggressive lipid management, those that develop our knowledge of ris!. assessment, and those that discuss the genetic, bio~hemical, and biophysical mechanisms underlying the pathology of coronary heart disease. On the clinical front, further analysis of the results of the Scandinavian Simvastatin Survival Study (4S) has indicated the cost-effectiveness of therapy in patients with established coronary heart disease. The West of Scotland Coronary Prevention Study (WOSCOPS), whose methodology was described at the DALM XII symposium, has demonstrated in a mostly primary-prevention population what 4S demonstrated for secondary prevention the year before: aggressive lipid-regulating therapy reduces coronary heart disease morbidity and mortality rates without concurrently increasing mortality from noncardiovascular causes. In the future, important considerations will be to develop protocols that maximize benefit in groups underrepresented in traditional clinical research for example, women and the elderly-and to improve compliance to existing treatment regimens. Furthermore, antioxidant, omega-3 fatty acid, and gene therapies warrant further investigation.
Book Synopsis Myocardial Ischemia: Mechanisms, Reperfusion, Protection by : Morris Karmazyn
Download or read book Myocardial Ischemia: Mechanisms, Reperfusion, Protection written by Morris Karmazyn and published by Birkhäuser. This book was released on 2013-03-12 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial ischemia and subsequent reperfusion of the ischemic myocardium represent complex phenomena encompassing numerous physiological processes. This book aims at enhancing our understanding of these processes and stresses recent important developments in this very active area of research. The concise, state-of-the-art reviews cover recent advances in many fields important to the area of myocardial ischemia and reperfusion including physiology, pathology, pharmacology, biochemistry and molecular biology with reference to clinical relevance and applicability of these findings. Major areas which are highlighted include vascular mechanisms resulting in myocardial ischemia, cellular events in the ischemic, postinfarcted and reperfused myocardium as well as new exciting developments in cardiac protection that involve both novel pharmacological approaches as well as endogenous cardioprotective mechanisms such as preconditioning. Aimed at both the basic and clinical cardiovascular investigator, the book comprehensively reviews the rapid progress made in recent years in understanding the etiology of myocardial ischemia and reperfusion. It will further serve as an authoritative reference for all those interested in learning about the important developments in the treatment of myocardial ischemic and reperfusion disorders.
Book Synopsis Myocardial Energy Metabolism by : J.W. de Jong
Download or read book Myocardial Energy Metabolism written by J.W. de Jong and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lipid Metabolism and Atherosclerosis by : Dennis W. K. Cotton
Download or read book Lipid Metabolism and Atherosclerosis written by Dennis W. K. Cotton and published by . This book was released on 1973 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
