Mutations

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Mobilizing Mutations

Author : Daniel Navon
Publisher : University of Chicago Press
ISBN 13 : 022663809X
Total Pages : 409 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis Mobilizing Mutations by : Daniel Navon

Download or read book Mobilizing Mutations written by Daniel Navon and published by University of Chicago Press. This book was released on 2019-09-20 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: With every passing year, more and more people learn that they or their young or unborn child carries a genetic mutation. But what does this mean for the way we understand a person? Today, genetic mutations are being used to diagnose novel conditions like the XYY, Fragile X, NGLY1 mutation, and 22q11.2 Deletion syndromes, carving out rich new categories of human disease and difference. Daniel Navon calls this form of categorization “genomic designation,” and in Mobilizing Mutations he shows how mutations, and the social factors that surround them, are reshaping human classification. Drawing on a wealth of fieldwork and historical material, Navon presents a sociological account of the ways genetic mutations have been mobilized and transformed in the sixty years since it became possible to see abnormal human genomes, providing a new vista onto the myriad ways contemporary genetic testing can transform people’s lives. Taking us inside these shifting worlds of research and advocacy over the last half century, Navon reveals the ways in which knowledge about genetic mutations can redefine what it means to be ill, different, and ultimately, human.

Mutation

Author : Robin Cook
Publisher : Penguin
ISBN 13 : 9780425119655
Total Pages : 356 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Mutation by : Robin Cook

Download or read book Mutation written by Robin Cook and published by Penguin. This book was released on 1990-02-01 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this masterpiece of techno-medical suspense from the “master of the medical thriller” (The New York Times), Robin Cook tells the explosive tale of a brilliant doctor who sought to create the son of his dreams—and invented a living nightmare... When OB/GYN and biomolecular researcher Dr. Victor Frank learns of his wife’s infertility, he initiates a bold—and dangerous—experiment. Unbeknownst to everyone, including her, Dr. Frank has adapted the methods of animal husbandry and molecular genetics to human reproduction. Fusing his wife’s eggs and his own sperm, he sets in motion the production of a superior being, his child. The result of this experiment, a son, VJ, is born to a surrogate mother and legally adopted by the Franks. To their delight, their son is physically perfect, and by the age of three, displays the complex problem-solving abilities of a prodigy. Then, without warning, VJ’s intelligence level plunges to a point appropriate to his age, but stabilizes. For the moment, Dr. Frank can breathe a sigh of relief: even if VJ is no longer the genius he was, at least he will be normal. But that relief is tragically short-lived, for all too soon VJ begins to change again. And this time, there is no cause for comfort—only terror.

Mutations

Author : Sam McPheeters
Publisher : Barnacle Book
ISBN 13 : 9781947856981
Total Pages : 312 pages
Book Rating : 4.8/5 (569 download)

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Book Synopsis Mutations by : Sam McPheeters

Download or read book Mutations written by Sam McPheeters and published by Barnacle Book. This book was released on 2020-02-11 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: How can so many people pledge allegiance to punk, something with no fixed identity? Depending on who and where you are, punk can be an outlet, excuse, lifestyle, escapism, conversation, community, ideology, sales category, social movement, punishable offense, badge of authenticity, reason to drink beer forever, or an aesthetic of belligerent incompetence. And if someone has a strong belief about what punk is, odds are they have even stronger feelings about what punk is not. Sam McPheeters championed many different versions. Over the course of two decades, he fronted Born Against, released dozens of records and fanzines, and toured seventeen times across the northern hemisphere. In this collection of essays, profiles, criticism, and personal history, he examines the diverse realms he intersected--New York hardcore, Riot Grrrl, Gilman street, the hidden enclaves of Olympia, and New England, and downtown Los Angeles--and the forces of mental illness and creative inspiration that drove him, and others, in the first place.

Mutation-Driven Evolution

Author : Masatoshi Nei
Publisher : OUP Oxford
ISBN 13 : 0199661731
Total Pages : 261 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Mutation-Driven Evolution by : Masatoshi Nei

Download or read book Mutation-Driven Evolution written by Masatoshi Nei and published by OUP Oxford. This book was released on 2013-05-02 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to present a new theory of mutation-driven evolution, which is based on recent advances in genomics and evolutionary developmental biology. This theory asserts that the driving force of evolution is mutation and natural selection is of secondary importance.

The Mutations

Author : Jorge Comensal
Publisher : Picador
ISBN 13 : 9781250758125
Total Pages : 192 pages
Book Rating : 4.7/5 (581 download)

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Book Synopsis The Mutations by : Jorge Comensal

Download or read book The Mutations written by Jorge Comensal and published by Picador. This book was released on 2020-11-17 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Jorge Comensal's The Mutations oscillates masterfully between comedy and tragedy, gathering up in its pages a stupendous panoply of characters before whom the reader is never sure whether to smile in sympathy or pity."—Fernando Aramburu, author of Homeland Ramón Martinez is a militant atheist, successful lawyer, and conventional family man. But all of that changes when cancer of the tongue deprives him of the source of his power and livelihood: speech. The Mutations, by Jorge Comensal, is a comedy tracing the metastasis of Ramón’s cancer through his body and in the lives of his family members, colleagues, and doctors, dissecting the experience of illness and mapping the relationships both strengthened and frayed by its wake. Mateo and Paulina, his teenage children, struggle with the temptations of masturbation and binge eating, respectively. Ramón’s melancholic oncologist is haunted by the memory of a young patient whom he was unable to save. His selfish pathologist believes Ramón’s tumor holds the key to a major scientific breakthrough. And then there’s Elodia, Ramón’s pious maid, who brings him a foulmouthed parrot as a birthday gift. This lewd bird becomes Ramón’s companion, confidant, and unlikely double. Paying homage to the works of forebears such as Sontag, Didion, Flaubert, and Tolstoy, and filled with a rough-hewn poetry of regret, rage, and finally resignation, The Mutations offers a profound but funny cross section of modern Mexican life, as well as a bold treatment of an unspeakable yet universal reality

Health Effects of Exposure to Low Levels of Ionizing Radiation

Author : National Research Council
Publisher : National Academies
ISBN 13 : 0309039959
Total Pages : 436 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Health Effects of Exposure to Low Levels of Ionizing Radiation by : National Research Council

Download or read book Health Effects of Exposure to Low Levels of Ionizing Radiation written by National Research Council and published by National Academies. This book was released on 1990-02-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.

Crumbling Genome

Author : Alexey S. Kondrashov
Publisher : John Wiley & Sons
ISBN 13 : 1118952111
Total Pages : 309 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Crumbling Genome by : Alexey S. Kondrashov

Download or read book Crumbling Genome written by Alexey S. Kondrashov and published by John Wiley & Sons. This book was released on 2017-07-12 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that are caused, exclusively or primarily, by pre ]existing and new mutations in their genomes, including both a wide variety of genetically simple Mendelian diseases and diverse complex diseases such as birth anomalies, diabetes, and schizophrenia. Milder, but still substantial, negative effects of mutations are even more pervasive. As of now, we possess no means of reducing the rate at which mutations appear spontaneously. However, the recent flood of genomic data made possible by next-generation methods of DNA sequencing, enabled scientists to explore the impacts of deleterious mutations on humans with previously unattainable precision and begin to develop approaches to managing them. Written by a leading researcher in the field of evolutionary genetics, Crumbling Genome reviews the current state of knowledge about deleterious mutations and their effects on humans for those in the biological sciences and medicine, as well as for readers with only a general scientific literacy and an interest in human genetics. Provides an extensive introduction to the fundamentals of evolutionary genetics with an emphasis on mutation and selection Discusses the effects of pre-existing and new mutations on human genotypes and phenotypes Provides a comprehensive review of the current state of knowledge in the field and considers crucial unsolved problems Explores key ethical, scientific, and social issues likely to become relevant in the near future as the modification of human germline genotypes becomes technically feasible Crumbling Genome is must-reading for students and professionals in human genetics, genomics, bioinformatics, evolutionary biology, and biological anthropology. It is certain to have great appeal among all those with an interest in the links between genetics and evolution and how they are likely to influence the future of human health, medicine, and society.

Movie Mutations: The Changing Face of World Cinephilia

Author : Jonathan Rosenbaum
Publisher : British Film Institute
ISBN 13 : 9780851709840
Total Pages : 196 pages
Book Rating : 4.7/5 (98 download)

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Book Synopsis Movie Mutations: The Changing Face of World Cinephilia by : Jonathan Rosenbaum

Download or read book Movie Mutations: The Changing Face of World Cinephilia written by Jonathan Rosenbaum and published by British Film Institute. This book was released on 2003-12-02 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: In contrast to any talk of "the death of the cinema", this title pronounces the art form alive and well, and still developing in new and unforeseen directions. Using transnational discussions and debates, it shows why the idea of cinephilia is just as relevant today as it ever was.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mutation

Author : Elof Axel Carlson
Publisher :
ISBN 13 : 9781936113309
Total Pages : 0 pages
Book Rating : 4.1/5 (133 download)

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Book Synopsis Mutation by : Elof Axel Carlson

Download or read book Mutation written by Elof Axel Carlson and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea of mutation has changed considerably from the pre-Mendelian concepts of Darwin's generation to today's up-to-the-minute genomic context of mutation. The historical approach taken by History of Mutation reveals the way science works, incrementally by small steps rather than by dramatic, and rare, paradigm shifts.

Biotechnologies for Plant Mutation Breeding

Author : Joanna Jankowicz-Cieslak
Publisher : Springer
ISBN 13 : 3319450212
Total Pages : 343 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Biotechnologies for Plant Mutation Breeding by : Joanna Jankowicz-Cieslak

Download or read book Biotechnologies for Plant Mutation Breeding written by Joanna Jankowicz-Cieslak and published by Springer. This book was released on 2016-12-08 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY-NC 2.5 license. This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by sequencing, doubled haploidy, targeted genome editing, and low-cost methods for the molecular characterization of mutant plants that are suitable for laboratories in developing countries. The collection of protocols equips users with the techniques they need in order to start a program on mutation breeding or functional genomics using both forward and reverse-genetic approaches. Methods are provided for seed and vegetatively propagated crops (e.g. banana, barley, cassava, jatropha, rice) and can be adapted for use in other species.

Mutated

Author : Joe McKinney
Publisher : Pinnacle Books
ISBN 13 : 0786030534
Total Pages : 416 pages
Book Rating : 4.7/5 (86 download)

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Book Synopsis Mutated by : Joe McKinney

Download or read book Mutated written by Joe McKinney and published by Pinnacle Books . This book was released on 2011-10-24 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: They Outnumber The Living. . . 25 to 1. Those are the odds of being struck down--and resurrected--by the savage plague that's sweeping the country, forcing survivors to band together against the dead. They're Growing Stronger. . . Even among the living, there is dissention. A new leader known as the Red Man has risen up and taken charge--and he's nearly as dangerous as the hungry dead. Some, like Bob Richardson and his friends, strike out on their own. Because if the men with guns don't get them, the zombies will. They're Getting Smarter. . . Fleeing the cities, Richardson and his crew find sanctuary in an abandoned farm. But their stronghold may not be strong enough. Something strange and terrifying is happening to the undead. They're banding together. Working as a group. Hungering for a common goal: human flesh. And lots of it. Praise for Joe McKinney and His Novels "A merciless, fast-paced and genuinely scary read that will leave you absolutely breathless." --Bram Stoker Award-winning author Brian Keene on Dead City "A fantastic tale of survival horror that starts with a bang and never lets up." --Zombiehub.com "A rising star on the horror scene."--Fearnet.com

Sound Mutations

Author : Degif Petros Banksira
Publisher : John Benjamins Publishing
ISBN 13 : 9027298475
Total Pages : 366 pages
Book Rating : 4.0/5 (272 download)

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Book Synopsis Sound Mutations by : Degif Petros Banksira

Download or read book Sound Mutations written by Degif Petros Banksira and published by John Benjamins Publishing. This book was released on 2000-10-20 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph, which evolved from the first linguistic dissertation to be written on Chaha (an Ethiopian Semitic language), is also the first book to deal exclusively with the phonology and morphology of the language. It is an exhaustive description and analysis, by a native speaker, of the sound patterns of this often misdescribed language and deserves to be the standard reference on the phonology of Chaha. The book presents a vast amount of new data and it unearths some fascinating new generalizations about double linking, geminate devoicing, nasalization of liquid consonants, phonotactic constraints within morphemes, and palatalization and labialization triggered by decomposition of a single back high round vowel. The book also challenges the categorization of Semitic subject affixes into prefix and suffix sets, instead proposing a novel classification in which all prefixes and some suffixes form a set that excludes the remaining suffixes. The generalizations and analyses are significant not only for the study of Chaha and Semitic languages, but also for phonological theory in general.

Somaclonal Variation and Induced Mutations in Crop Improvement

Author : S.M. Jain
Publisher : Springer Science & Business Media
ISBN 13 : 9401591253
Total Pages : 615 pages
Book Rating : 4.4/5 (15 download)

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Book Synopsis Somaclonal Variation and Induced Mutations in Crop Improvement by : S.M. Jain

Download or read book Somaclonal Variation and Induced Mutations in Crop Improvement written by S.M. Jain and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic variability is an important parameter for plant breeders in any con ventional crop improvement programme. Very often the desired variation is un available in the right combination, or simply does not exist at all. However, plant breeders have successfully recombined the desired genes from cultivated crop gerrnplasm and related wild species by sexual hybridization, and have been able to develop new cultivars with desirable agronomie traits, such as high yield, disease, pest, and drought resistance. So far, conventional breeding methods have managed to feed the world's ever-growing population. Continued population growth, no further scope of expanding arable land, soil degradation, environ mental pollution and global warrning are causes of concern to plant biologists and planners. Plant breeders are under continuous pressure to improve and develop new cultivars for sustainable food production. However, it takes several years to develop a new cultivar. Therefore, they have to look for new technologies, which could be combined with conventional methods to create more genetic variability, and reduce the time in developing new cultivars, with early-maturity, and improved yield. The first report on induced mutation of a gene by HJ. Muller in 1927 was a major mi1estone in enhancing variation, and also indicated the potential applica tions of mutagenesis in plant improvement. Radiation sources, such as X-rays, gamma rays and fast neutrons, and chemical mutagens (e. g. , ethyl methane sulphonate) have been widely used to induce mutations.

Mutation Breeding

Author : A. M. van Harten
Publisher : Cambridge University Press
ISBN 13 : 9780521470742
Total Pages : 372 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis Mutation Breeding by : A. M. van Harten

Download or read book Mutation Breeding written by A. M. van Harten and published by Cambridge University Press. This book was released on 1998-06-25 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential and comprehensive summary for all plant breeders.

Lateness

Author : Peter Eisenman
Publisher : Princeton University Press
ISBN 13 : 0691203911
Total Pages : 120 pages
Book Rating : 4.6/5 (912 download)

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Book Synopsis Lateness by : Peter Eisenman

Download or read book Lateness written by Peter Eisenman and published by Princeton University Press. This book was released on 2020-07-07 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: A provocative case for historical ambiguity in architecture by one of the field's leading theorists Conceptions of modernity in architecture are often expressed in the idea of the zeitgeist, or "spirit of the age," an attitude toward architectural form that is embedded in a belief in progressive time. Lateness explores how architecture can work against these linear currents in startling and compelling ways. In this incisive book, internationally renowned architect Peter Eisenman, with Elisa Iturbe, proposes a different perspective on form and time in architecture, one that circumvents the temporal constraints on style that require it to be "of the times"—lateness. He focuses on three twentieth-century architects who exhibited the qualities of lateness in their designs: Adolf Loos, Aldo Rossi, and John Hejduk. Drawing on the critical theory of Theodor Adorno and his study of Beethoven's final works, Eisenman shows how the architecture of these canonical figures was temporally out of sync with conventions and expectations, and how lateness can serve as a form of release from the restraints of the moment. Bringing together architecture, music, and philosophy, and drawing on illuminating examples from the Renaissance and Baroque periods, Lateness demonstrates how today's architecture can use the concept of lateness to break free of stylistic limitations, expand architecture's critical capacity, and provide a new mode of analysis.

Project Japan

Author : Rem Koolhaas
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Project Japan by : Rem Koolhaas

Download or read book Project Japan written by Rem Koolhaas and published by . This book was released on 2011 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism was a movement launched in Japan that took inspiration for buildings and cities from biological systems. With interviews and commentary and hundreds of images, Project Japan unearths a history that casts new light on the key issues that both enervate and motivate architecture today.