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Author : Zoltán Sándor
Publisher :
ISBN 13 :
Total Pages : 142 pages
Book Rating : 4.3/5 (91 download)
Download or read book Mutagenic Properties of Psoralen-modified Triple Helix Forming Oligonucleotides written by Zoltán Sándor and published by . This book was released on 1998 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Edward Joseph Gunther
Publisher :
ISBN 13 :
Total Pages : 148 pages
Book Rating : 4.:/5 (72 download)
Download or read book Mutagenesis Induced by Free Psoralen and Psoralen Linked to a Sequence-specific Triple Helix-forming Oligonucleotide written by Edward Joseph Gunther and published by . This book was released on 1993 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Claude Malvy
Publisher : Springer Science & Business Media
ISBN 13 : 1461551773
Total Pages : 296 pages
Book Rating : 4.4/5 (615 download)
Download or read book Triple Helix Forming Oligonucleotides written by Claude Malvy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence-specific DNA binding ligands, amongst which triple helix forming oligonucleotides are the most efficient as yet, represent promising tools in a number of fields. One of their most promising applications is as antiviral tools: they can specifically target a viral gene, even if it is integrated into the host genome, and be used to specifically inactivate the viral gene or even destroy the cells harboring this gene. However, from science fiction to science there remains a gap; and we are at the moment on the threshold of this fascinating field. Triple Helix Forming Oligonucleotides considers the different aspects of the design and improvement, current or future, of these molecules and their structural analysis, as well as their applications, with special emphasis on the attempts to obtain biological effects of these potentially important tools. What emerges is that the current state of the research is encouraging, and that these molecules are already useful in some biotechnology applications.
Author :
Publisher :
ISBN 13 :
Total Pages : 1840 pages
Book Rating : 4.3/5 (243 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1840 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stanley T. Crooke
Publisher : Springer Science & Business Media
ISBN 13 : 3642587852
Total Pages : 646 pages
Book Rating : 4.6/5 (425 download)
Download or read book Antisense Research and Application written by Stanley T. Crooke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antisense technology may result in dramatic changes in the therapy of many diseases and may provide tools to dissect pharmacological processes and to confirm the roles of various genes. In this volume, progress in the understanding of antisense technology and its use in creating new drugs is discussed. Potential caveats, pitfalls and limitations of the technology are also presented. In the next few years the pace at which new molecular targets will be identified will increase exponentially as the sequencing of the human genome and of other genomes proceeds.
Author : Ramon Eritja
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 311063953X
Total Pages : 380 pages
Book Rating : 4.1/5 (16 download)
Download or read book Nucleic Acids Chemistry written by Ramon Eritja and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-01-18 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles recent research on the modification of nucleic acids. It covers backbone modifications and conjugation of lipids, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed as well.
Author : Karl G. Blume
Publisher : John Wiley & Sons
ISBN 13 : 1405140119
Total Pages : 1618 pages
Book Rating : 4.4/5 (51 download)
Download or read book Thomas' Hematopoietic Cell Transplantation written by Karl G. Blume and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 1618 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW - the leading book in its field now fully updated andrevised! Click here to access two FREE sample chapters! An Essential resource for all hematologists, oncologists,pathologists, pediatricians, immunologists and all othersinterested in this dynamic area of medicine! Why you should buy this book.... Extensive coverage of subject area - from the scientific basisto the view of the future Includes all experimental research and clinicalapplication Combined the knowledge and expertise of over 170 internationalspecialists Clear structure and layout Over 500 illustrations, including a colour plate section Why buy the NEW edition...... New and fully revised to reflect the latest developments inthis fast moving field 10 new chapters, covering some of the latest developments - seebelow for the complete tables of content
Author :
Publisher :
ISBN 13 :
Total Pages : 918 pages
Book Rating : 4.X/5 (6 download)
Download or read book Nucleic Acids Abstracts written by and published by . This book was released on 1997 with total page 918 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Richard R. Sinden
Publisher : Elsevier
ISBN 13 : 0080571735
Total Pages : 423 pages
Book Rating : 4.0/5 (85 download)
Download or read book DNA Structure and Function written by Richard R. Sinden and published by Elsevier. This book was released on 2012-12-02 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Structure and Function, a timely and comprehensive resource, is intended for any student or scientist interested in DNA structure and its biological implications. The book provides a simple yet comprehensive introduction to nearly all aspects of DNA structure. It also explains current ideas on the biological significance of classic and alternative DNA conformations. Suitable for graduate courses on DNA structure and nucleic acids, the text is also excellent supplemental reading for courses in general biochemistry, molecular biology, and genetics. - Explains basic DNA Structure and function clearly and simply - Contains up-to-date coverage of cruciforms, Z-DNA, triplex DNA, and other DNA conformations - Discusses DNA-protein interactions, chromosomal organization, and biological implications of structure - Highlights key experiments and ideas within boxed sections - Illustrated with 150 diagrams and figures that convey structural and experimental concepts
Author :
Publisher :
ISBN 13 :
Total Pages : 550 pages
Book Rating : 4.3/5 (91 download)
Download or read book Genetics Abstracts written by and published by . This book was released on 1994 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alfred Pingoud
Publisher : Springer Science & Business Media
ISBN 13 : 3642188516
Total Pages : 462 pages
Book Rating : 4.6/5 (421 download)
Download or read book Restriction Endonucleases written by Alfred Pingoud and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Restriction enzymes are highly specific nucleases which occur ubiquitously among prokaryotic organisms, where they serve to protect bacterial cells against foreign DNA. Many different types of restriction enzymes are known, among them multi-subunit enzymes which depend on ATP or GTP hydrolysis for target site location. The best known representatives, the orthodox type II restriction endonucleases, are homodimers which recognize palindromic sequences, 4 to 8 base pairs in length, and cleave the DNA within or immediately adjacent to the recognition site. In addition to their important biological role (up to 10 % of the genomes of prokaryotic organisms code for restriction/modification systems!), they are among the most important enzymes used for the analysis and recombination of DNA. In addition, they are model systems for the study of protein-nucleic acids interactions and, because of their ubiquitous occurence, also for the understanding of the mechanisms of evolution.
Author :
Publisher :
ISBN 13 :
Total Pages : 682 pages
Book Rating : 4.:/5 ( download)
Download or read book Antisense & Nucleic Acid Drug Development written by and published by . This book was released on 1997 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stanley T. Crooke
Publisher : CRC Press
ISBN 13 : 9780824705664
Total Pages : 2004 pages
Book Rating : 4.7/5 (56 download)
Download or read book Antisense Drug Technology written by Stanley T. Crooke and published by CRC Press. This book was released on 2001-09-14 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of-the-art reference provides comprehensive coverage of the development of antisense oligonucleotides to inhibit cancer cells as well as those involved in infectious, inflammatory, and immune-mediated diseases-highlighting new tools and technologies in medicinal chemistry, RNA biochemistry, and molecular and cellular biology to produce new therapeutic compounds. Presents previously unpublished data on the use of antisense technology to dissect pharmacological processes and confirm the roles of various genes! Showcasing the benefits of antisense drug use, including reduced toxicity and earlier disease detection, Antisense Drug Technology discusses novel formulations of antisense drugs practical methods to design effective isotype selective inhibitors molecular mechanisms of antisense drugs mRNA as a current biological template modern postreceptor binding mechanisms and more! With contributions by over 60 seasoned experts in the field and containing more than 3000 helpful references, tables, drawings, and photographs, Antisense Drug Technology is an illuminating source for organic, medicinal, and pharmaceutical chemists; biochemists; geneticists; hematologists; oncologists; molecular and cell biologists; virologists; immunologists; and medical school and graduate students in these disciplines.
Author : Daniel Scherman
Publisher : World Scientific
ISBN 13 : 1783263148
Total Pages : 557 pages
Book Rating : 4.7/5 (832 download)
Download or read book Advanced Textbook On Gene Transfer, Gene Therapy And Genetic Pharmacology: Principles, Delivery And Pharmacological And Biomedical Applications Of Nucleotide-based Therapies written by Daniel Scherman and published by World Scientific. This book was released on 2013-12-10 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique advanced textbook provides a clear and comprehensive description of the field of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations.The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of revolutionary gene therapy strategies. In this advanced textbook, more than 25 leading scientists, world-renowned in their respective fields, come together to provide a clear and comprehensive description of gene delivery, gene therapy and genetic pharmacology.This educational introduction to the main gene transfer vectors and selected therapeutic applications provides the background material needed to further explore the subject as well as relevant research literature. It will thus be invaluable to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide, or develop a gene therapy strategy. Furthermore, the textbook's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Author : National Academy of Sciences (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1460 pages
Book Rating : 4.:/5 (319 download)
Download or read book Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.) and published by . This book was released on 1991 with total page 1460 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Proceedings of the National Academy of Sciences (PNAS) publishes research reports, commentaries, reviews, colloquium papers, and actions of the Academy. PNAS is a multidisciplinary journal that covers the biological, physical, and social sciences.
Author : Cy A. Stein
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 556 pages
Book Rating : 4.3/5 (91 download)
Download or read book Applied Antisense Oligonucleotide Technology written by Cy A. Stein and published by Wiley-Liss. This book was released on 1998-03-19 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied Antisense Oligonucleotide Technology provides the basic concepts as well as the practical concerns associated with the use of antisense oligonucleotides to modify gene expression. Chapters include oligonucleotide chemistry, DNA triplex formation, delivery mechanisms, pharmocokinetics, toxicity, oligonucleotides.
Author : Wentao Xu
Publisher : Springer
ISBN 13 : 9811016186
Total Pages : 484 pages
Book Rating : 4.8/5 (11 download)
Download or read book Functional Nucleic Acids Detection in Food Safety written by Wentao Xu and published by Springer. This book was released on 2016-09-08 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the development and applications of functional nucleic acid-based detection methods in the context of food safety. Offering a comprehensive overview of nucleic acids detection method in food safety for professionals and members of the public interested in this area, the book is divided into two parts. Part I addresses the basic principle of nucleic acid detection, while Part II presents novel applications of detection methods in genetically modified organisms, the identification of dead-alive microorganisms, microbial diversity, heavy metal detection, gene toxicity and non-coding RNA identification. As such, it provides readers a wealth of knowledge on the use of nucleic acids as targets and media in food safety. It offers a valuable resource for clinicians and basic scientists in the areas of food science and microbiology, and for all those who are interested in the concrete applications of molecular biological techniques. p>
