Multidisciplinary Approaches to Common Surgical Problems

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Publisher : Springer
ISBN 13 : 3030128237
Total Pages : 471 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Multidisciplinary Approaches to Common Surgical Problems by : Robert Lim

Download or read book Multidisciplinary Approaches to Common Surgical Problems written by Robert Lim and published by Springer. This book was released on 2019-06-21 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emergent general surgical diseases are the most frequent causes of in-hospital deaths and are the most costly diseases to treat. The purpose of this book is to provide clinicians with an understanding of their roles and that of other disciplines for the treatment of acute and emergent surgical diseases. It is also designed to give a clear pathway for using multiple disciplines to manage these diseases. The text details over 20 problems routinely seen in clinical practice and approaches the disease from the perspective of experts within the different specialties. It provides a comprehensive, evidenced-based overview and the most up-to-date technology available in clinical practice. An emphasis on new, less invasive techniques that may have a broader range of indications in the future is also included. Ultimately the reader will have a better understanding of these acute problems, the other specialties they work with, and when to integrate these other specialties when they encounter these urgent clinical scenarios.

Multidisciplinary Approach to Surgical Oncology Patients

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Publisher : Springer Nature
ISBN 13 : 9811576998
Total Pages : 358 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Multidisciplinary Approach to Surgical Oncology Patients by : M. D. Ray

Download or read book Multidisciplinary Approach to Surgical Oncology Patients written by M. D. Ray and published by Springer Nature. This book was released on 2021-03-02 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book covers the basic concept of surgical and oncosurgical disciplines as a whole, as well as the management of surgical patients from pre-op preparation to discharge, i.e., all the basics needed for a successful outcome for oncosurgical patients. It covers surgical safety, the consumer protection act, medico-legal aspects, the importance of documentation, research and publications, and managing complications. The respective chapters cover pre-operative, intra-operative, and ICU management of cancer patients, based on a multi-disciplinary approach. Additionally, they highlight recent advances in surgical oncology and so-called incurable cancers. Edited and written by an interdisciplinary team of experts in oncology and palliative care, the book is intended as a clinically useful guide to the overlapping topics of pain management in cancer patients and the treatment of cancer in patients with multiple co-morbidities like cardiovascular, respiratory disease, hypertension and diabetes mellitus. Given its scope, it will benefit multi-disciplinary oncologists, pain, palliative and intensive care experts, as well as students of surgical disciplines, from MBBS, MS and DNB, to MRCS, MCh and FRCS.

Surgical Oncology

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Publisher :
ISBN 13 :
Total Pages : 788 pages
Book Rating : 4.:/5 (128 download)

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Book Synopsis Surgical Oncology by : Howard Silberman

Download or read book Surgical Oncology written by Howard Silberman and published by . This book was released on 2002 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles and Practice of Surgical Oncology

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451153236
Total Pages : 1127 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Principles and Practice of Surgical Oncology by : Howard Silberman

Download or read book Principles and Practice of Surgical Oncology written by Howard Silberman and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Practice of Surgical Oncology uniquely emphasizes a multidisciplinary, integrated approach to the treatment of solid tumors. It presents treatment strategies that combine surgery with preoperative or postoperative adjunctive chemotherapy, hormonal therapy, and/or radiation therapy to achieve optimal outcome. The book features contributions from surgeons, basic scientists, pathologists, radiologists, radiation therapists, and medical oncologists and offers a comprehensive presentation of genetics, molecular biology, pathogenesis, and multimodal therapeutic approaches. A unique feature of the book is a commentary following each chapter, which describes alternative approaches and discusses controversial areas of current therapy. A companion Website will offer the fully searchable text with images.

Peripheral Nerve Issues after Orthopedic Surgery

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Publisher : Springer Nature
ISBN 13 : 3030844285
Total Pages : 431 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Peripheral Nerve Issues after Orthopedic Surgery by : Christopher J. Dy

Download or read book Peripheral Nerve Issues after Orthopedic Surgery written by Christopher J. Dy and published by Springer Nature. This book was released on 2021-11-15 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peripheral nerve issues are potential sequalae of orthopedic surgery, even after cases in which technically excellent surgery was performed. These injuries can impede the expected recovery of function after the primary surgery. Given the manifold challenges associated with recovery of peripheral nerve injuries, this book is designed as a multidisciplinary guide to the diagnosis, prognostication and treatment of peripheral nerve issues after common orthopedic surgeries. Beginning with an overview of nerve compression, injury and regeneration, as well as a presentation of the current diagnostic and imaging modalities for peripheral nerve injuries, this unique text is organized by anatomic region and by type of procedure performed. Topics covered include shoulder and elbow arthroplasty and arthroscopy, fractures of the hand and wrist, hip preservation surgery, total knee replacement, open surgery of the foot and ankle, lumbosacral myeloradiculopathy, and more. Each chapter is authored by both a subspecialty surgeon who routinely performs the surgeries described and a subspecialized hand/peripheral nerve surgeon with experience in evaluating and treating nerve issues after that particular injury. Emphasis is placed on multidisciplinary team approaches, patient counseling, and technical aspects of surgical treatment. Generously illustrated and written by experts in the field, Peripheral Nerve Issues after Orthopedic Surgery is a truly interdisciplinary resource for orthopedic, plastic, hand and trauma surgeons, physiatrists, trainees, and all professionals evaluating and managing postoperative peripheral nerve issues.

Surgical Decision Making in Geriatrics

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Publisher : Springer Nature
ISBN 13 : 3030479633
Total Pages : 452 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Surgical Decision Making in Geriatrics by : Rifat Latifi

Download or read book Surgical Decision Making in Geriatrics written by Rifat Latifi and published by Springer Nature. This book was released on 2020-08-12 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to present a comprehensive and state-of the-art approach to all aspects of geriatric surgery within the broad confines of surgery in geriatrics including general surgery, neurosurgery, thoracic surgery, vascular surgery, cardiac surgery, surgical oncology, hepatobiliary and transplant surgery, plastic, colorectal, orthopedic, gynecologic, and urologic surgery. The text is split into four parts. The first part is organized under general considerations on the geriatric surgical patient and includes current trends in geriatric surgery, and a number of important general issues such as practical approaches to reversal of bleeding/anticoagulation, role of anesthetic concerns in advanced age, frailty index and measurements of physiological reserves, nutritional support in the elderly, quality of life in the elderly, drug use, and family involvement. Part two of the book focuses on surgery specific system-based problems in geriatric surgical patients. The third part addresses many other important aspects of geriatric surgery including palliative and end of life care for the elderly, religious issues and the elderly care surgery, elderly with mental health issues, and nursing care of elderly patients. The fourth and final part describes the need for geriatric surgical care education and the components that are essential for the curriculum of current and future generations of students. Written by experts in the field, Surgical Decision Making in Geriatrics addresses patient selection, pre-operative considerations, technical conduct of the most common operations, and avoiding complications.

Head and Neck Cancer

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781771368
Total Pages : 1004 pages
Book Rating : 4.7/5 (713 download)

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Book Synopsis Head and Neck Cancer by : Louis B. Harrison

Download or read book Head and Neck Cancer written by Louis B. Harrison and published by Lippincott Williams & Wilkins. This book was released on 2009 with total page 1004 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, multidisciplinary text addresses all aspects of head and neck cancer and represents a wide spectrum of specialists, including surgical, radiation, and medical oncologists, dentists, pathologists, radiologists, and nurses. The book focuses on a two-part approach to treatment that maximizes the chance for a cure while maintaining a strong emphasis on quality of life. This Third Edition's updated techniques section includes new radiation techniques such as IMRT and IGRT and new endoscopic and laser surgical techniques. Other highlights include a new chapter on reconstructive techniques; significant updates to all site-specific chapters; updates on chemoprevention and molecular targeting; and discussions of new imaging modalities such as fused PET/CT. A companion Website will offer the fully searchable text with all images.

Tüm Yönleri İle Proktoloji

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Author :
Publisher : Akademisyen Kitabevi
ISBN 13 : 6258125077
Total Pages : 123 pages
Book Rating : 4.2/5 (581 download)

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Book Synopsis Tüm Yönleri İle Proktoloji by : Tuba ERÜRKER ÖZTÜRK

Download or read book Tüm Yönleri İle Proktoloji written by Tuba ERÜRKER ÖZTÜRK and published by Akademisyen Kitabevi. This book was released on 2022-06-02 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gastrointestinal Diseases: A Multidisciplinary Approach, 1e (Clinics Collections)

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323428274
Total Pages : 642 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Gastrointestinal Diseases: A Multidisciplinary Approach, 1e (Clinics Collections) by : Joel J. Heidelbaugh

Download or read book Gastrointestinal Diseases: A Multidisciplinary Approach, 1e (Clinics Collections) written by Joel J. Heidelbaugh and published by Elsevier Health Sciences. This book was released on 2015-10-16 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinics Collections: Gastrointestinal Diseases draws from Elsevier’s robust Clinics Review Articles database to provide multidisciplinary teams, including general practitioners, gastroenterologists, otolaryngologists, oncologists, pathologists, and surgeons, with practical clinical advice and insights on this highly prevalent condition and its comorbidities. Clinics Collections: Gastrointestinal Diseases guides readers on how to apply current primary research findings on gastrointestinal diseases to everyday practice to help overcome challenges and complications, keep up with new and improved treatment methods, and improve patient outcomes. • Areas of focus include gastroesophageal reflux disease, Barrett’s esophagus, upper gastrointestinal bleeding, dyspepsia, eosinophilic esophagitis, gastroparesis, dysphagia, esophageal tumor, colon polyps/cancer, constipation, inflammatory bowel disease, gastroenteritis, lower gastrointestinal bleeding, and hemorrhoids. • Each article begins with keywords and key points for immediate access to the most critical information. • Articles are presented in an easy-to-digest and concisely worded format. Elsevier’s Clinics Collections provide concise reviews of today’s most prevalent conditions and significant medical developments. Other Clinics Collections titles available include Type II Diabetes Mellitus, Asthma, Obesity, Pain Management, Lipid Disorders, and Chronic Obstructive Pulmonary Disease.

"Venomous" Bites from "Non-Venomous" Snakes

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Author :
Publisher : Elsevier
ISBN 13 : 0128227877
Total Pages : 790 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis "Venomous" Bites from "Non-Venomous" Snakes by : Scott A Weinstein

Download or read book "Venomous" Bites from "Non-Venomous" Snakes written by Scott A Weinstein and published by Elsevier. This book was released on 2022-08-10 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Venomous" Bites from "Non-Venomous" Snakes, Second Edition thoroughly examines the potential hazards associated with bites by non-front-fanged snakes (popularly, but inaccurately, called "rear-fanged snakes"). This diverse group contains approximately 80% of living snake species (approximately 2,900 species). A large proportion of these snakes were previously assigned to the family Colubridae but, as a consequence of expanding systematics investigations, have been split into multiple families and subfamilies. Many of these snakes produce venoms or oral secretions that contain toxins and other biologically active substances. A large variety of non–front-fanged snakes figure in the pet industry, yet little documented information or formal study of their potential medical importance has been published. Therefore, although the possible medical importance of many of these species has been subjected to speculation since the mid-19th century, there is a limited amount of useful descriptive information regarding the real hazard (or lack thereof) of this wide variety of snakes. The first edition of this book provided "one-stop shopping" by offering information regarding their possible toxicity and clinical relevance as well as recommendations for medical management of their bites. The second edition expands and updates the content with detailed information about the effects and medical management of bites by a broad representation of non–front-fanged species. The hypothetical venomous nature of some lizards considered as non-venomous such as the Komodo monitor or dragon and their allies, as well as the medical effects of their bites, is also examined. The dynamic taxonomy of advanced snakes is updated, and the bases for some of these fluid changes are discussed. Likewise, terminology is also updated in order to reflect the ongoing debates regarding the definition of "venom" and the balanced reinforcement of nonmedical criteria used to define the biological basis of the term "venomous." - Fills a gap in toxicological, medical, and herpetological literature by providing a comprehensive review of this entire assemblage of non–front-fanged snakes, with particular attention given to their capacity to cause harm to humans - Offers a patient-centered, evidence-based approach which is applied to analyzing documented case reports of bites inflicted by a broad representation of species - Provides expanded and updated detailed information on the clinical management of medically significant bites from non–front-fanged snakes, which is also methodically reviewed, and specific recommendations are provided - Includes updates of the fluid taxonomy of advanced snakes and also of terminology with particular regard to the definition of "venom" and the nonmedical criteria used to define the biological basis of the "venomous condition" in snakes and lizards

Ehlers-Danlos Syndrome: A Multidisciplinary Approach

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Author :
Publisher : IOS Press
ISBN 13 : 1614998787
Total Pages : 370 pages
Book Rating : 4.6/5 (149 download)

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Book Synopsis Ehlers-Danlos Syndrome: A Multidisciplinary Approach by : J.W.G. Jacobs

Download or read book Ehlers-Danlos Syndrome: A Multidisciplinary Approach written by J.W.G. Jacobs and published by IOS Press. This book was released on 2018-08-14 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Generalized hypermobility has been known since ancient times, and a clinical description of Ehlers-Danlos syndrome (EDS) is said to have first been recorded by Hippocrates in 400 BC. Hypermobility syndromes occur frequently, but the wide spectrum of possible symptoms, coupled with a relative lack of awareness and recognition, are the reason that they are frequently not recognized, or remain undiagnosed. This book is an international, multidisciplinary guide to hypermobility syndromes, and EDS in particular. It aims to create better awareness of hypermobility syndromes among health professionals, including medical specialists, and to be a guide to the management of such syndromes for patients and practitioners. It is intended for use in daily clinical practice rather than as a reference book for research or the latest developments, and has been written to be understandable for any healthcare worker or educated patient without compromise to the scientific content. The book is organized as follows: chapters on classifications and genetics are followed by chapters on individual types, organ (system) manifestations and complications, and finally ethics and therapeutic strategies, with an appendix on surgery and the precautions which should attend it. A special effort has been made to take account of the perspective of the patient; two of the editors have EDS. The book will be of interest to patients with hypermobility syndromes and their families, as well as to all those healthcare practitioners who may encounter such syndromes in the course of their work.

Common Surgical Diseases

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Publisher : Springer
ISBN 13 : 1493915657
Total Pages : 330 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Common Surgical Diseases by : Theodore J. Saclarides

Download or read book Common Surgical Diseases written by Theodore J. Saclarides and published by Springer. This book was released on 2015-01-02 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leaders in the field, the third edition of Common Surgical Diseases: An Algorithmic Approach to Problem Solving, provides surgical residents and medical students with a current, concise and algorithmic approach to frequently encountered clinical challenges. Each chapter details every common surgical disease in the form of a succinct text coupled with step-by-step algorithm. It also walks the reader through the evaluation, diagnosis, treatment and follow-up of the most common surgical problems. Thoroughly updated and revised, the third edition focuses on problems most frequently encountered by general surgeons and their residents and students. More factual information is included in the form of charts and tables for quick and easy reference. The section on critical care is updated and expanded. The section on pre-operative considerations has new chapters on how to best manage patient's medications before surgery (anticoagulants, anti-platelet drugs) and prophylaxis of deep venous thrombosis. Other new chapters include access for hemodialysis, adrenal incidentaloma, esophageal cancer, pancreatic cancer, management of abdominal wall defects, hyperglycemia, necrotizing soft tissue infections and SIRS/sepsis. Especially pertinent in todays' medical environment is an understanding of the genetic component of certain cancers and chapters are devoted to screening and treating patients with genetic predispositions to colorectal and breast cancer.

Essential Foot and Ankle Surgical Techniques

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Publisher : Springer
ISBN 13 : 3030147789
Total Pages : 474 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Essential Foot and Ankle Surgical Techniques by : Christopher F. Hyer

Download or read book Essential Foot and Ankle Surgical Techniques written by Christopher F. Hyer and published by Springer. This book was released on 2019-07-23 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive textbook brings together a unique vision and multidisciplinary approach – embracing and combining MD, DO and DPM foot and ankle training disciplines – into a singular focus on improving and mastering surgical treatment of foot and ankle disorders. It opens with a chapter presenting the specific preoperative considerations and protocols commonly followed by foot and ankle surgeons of all specialties. Divided into three main thematic sections detailing the forefoot, midfoot and hindfoot, each subsequent chapter follows a consistent chapter format presenting case examples, key surgical set-up and equipment needs and step-by-step clinical pearls for surgical excellence. Post-operative care and rehabilitation recommendations are also included for a well-rounded presentation of care from start to finish. Both common and complex pathologies and injuries are discussed, from bunion and hammertoe management to the Charcot foot and ankle, total ankle replacement, arthroscopy and arthroplasty techniques, amputations and biologics. Generous figures and intraoperative photos illustrate the procedures in vivid detail. The subspecialty of foot and ankle surgery is a highly specialized one, which is constantly evolving and improving. This speaks to the complexity of the foot and ankle complex, the multiple levels and articulations of the foot and the variety of pathologies encountered. This textbook leans on the unique experience and training of the OFAC attending surgeons and past fellows to reveal the pearls and keys to the efficient surgical treatment of the full gamut of foot and ankle pathologies. Ideally suited for residents and students whether MD, DO or DPM, Essential Foot and Ankle Surgical Techniques - EFAST for short - is a dynamic, multidisciplinary resource that covers the full range of pathologies and injuries an orthopedic surgeon or podiatrist would encounter in daily practice.

Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, Eighth Edition

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Publisher : CRC Press
ISBN 13 : 0429812434
Total Pages : 4360 pages
Book Rating : 4.4/5 (298 download)

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Book Synopsis Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, Eighth Edition by : John Watkinson

Download or read book Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, Eighth Edition written by John Watkinson and published by CRC Press. This book was released on 2018-07-17 with total page 4360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scott-Brown's Otorhinolaryngology is used the world over as the definitive reference for trainee ENT surgeons, audiologists and trainee head and neck surgeons, as well as specialists who need detailed, reliable and authoritative information on all aspects of ear, nose and throat disease and treatment. Key points: accompanied by a fully searchable electronic edition, making it more accessible, containing the same content as the print edition, with operative videos and references linked to Medline highly illustrated in colour throughout to aid understanding updated by an international team of editors and contributors evidence-based guidelines will help you in your clinical practice features include key points, best clinical practice guidelines, details of the search strategies used to prepare the material and suggestions for future research new Endocrine section. Scott-Brown will provide trainee surgeons (ENT and Head and Neck), audiologists and ENT physicians with quick access to relevant information about clinical conditions, and provide them with a starting point for further research. The accompanying electronic edition, enhanced with operative videos, will enable both easy reference and accessibility on the move.

Pain Management: A Multidisciplinary Approach, 1e (Clinics Collections)

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323370748
Total Pages : 505 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Pain Management: A Multidisciplinary Approach, 1e (Clinics Collections) by : Joel J. Heidelbaugh

Download or read book Pain Management: A Multidisciplinary Approach, 1e (Clinics Collections) written by Joel J. Heidelbaugh and published by Elsevier Health Sciences. This book was released on 2015-10-15 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinics Collections: Pain Management draws from Elsevier’s robust Clinics Review Articles database to provide multidisciplinary teams, including general practitioners, orthopedists, obstetricians , neurologists, gastroenterologists, nurses, and other healthcare professionals, with practical clinical advice and insights on this highly prevalent disease and its comorbidities. Clinics Collections: Pain Management guides readers on how to apply current primary research findings on pain management to everyday practice to help overcome challenges and complications, keep up with new and improved treatment methods, and improve patient outcomes. Areas of focus include physiology and general management, musculoskeletal pain of the head,neck,upper body and lower body,as well as neurologic disorders, psychologic disorders, and special considerations. Each article begins with keywords and key points for immediate access to the most critical information. Articles are presented in an easy-to-digest and concisely worded format. Elsevier Clinics Collections provide concise reviews of today’s most prevalent conditions and significant medical developments. Other Clinics Collections titles available include Type II Diabetes Mellitus, Asthma, and Obesity.

Surgical Treatment of Pancreatic Diseases

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Publisher : Springer Science & Business Media
ISBN 13 : 8847008565
Total Pages : 526 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Surgical Treatment of Pancreatic Diseases by : Walter Siquini

Download or read book Surgical Treatment of Pancreatic Diseases written by Walter Siquini and published by Springer Science & Business Media. This book was released on 2010-05-30 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatic diseases are a crucial issue not only because of their epidemiological significance, and their anatomical and metabolic complexity, but also because of the different treatment options available and their implications for surgery. Due to the slow but steady increase in the incidence of pancreatitis and pancreatic cancer, these diseases are today a real challenge for the surgeon. This volume presents the state of the art of surgery in the treatment of inflammatory and neoplastic pancreatic diseases, describing in detail the different approaches and their most relevant technical aspects. Also described are conventional and interventional radiology, operative endoscopy and endoscopic ultrasonography (which has recently acquired a diagnostic role), and adjuvant and neoadjuvant therapy for treatment or palliation: for only a multidisciplinary approach can produce a global vision, a winning strategy for the optimization of results. Along with the texts, all written by experts, the volume includes color images and drawings. It will prove itself a very useful tool in clinical practice.

Global Gidelines for the Pevention of Surgical Site Infection

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Author :
Publisher :
ISBN 13 : 9789241549882
Total Pages : 184 pages
Book Rating : 4.5/5 (498 download)

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Book Synopsis Global Gidelines for the Pevention of Surgical Site Infection by : World Health Organization

Download or read book Global Gidelines for the Pevention of Surgical Site Infection written by World Health Organization and published by . This book was released on 2017-01-27 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surgical site infections are caused by bacteria that get in through incisions made during surgery. They threaten the lives of millions of patients each year and contribute to the spread of antibiotic resistance. In low- and middle-income countries, 11% of patients who undergo surgery are infected in the process. In Africa, up to 20% of women who have a caesarean section contract a wound infection, compromising their own health and their ability to care for their babies. But surgical site infections are not just a problem for poor countries. In the United States, they contribute to patients spending more than 400 000 extra days in hospital at a cost of an additional US $10 billion per year. No international evidence-based guidelines had previously been available before WHO launched its global guidelines on the prevention of surgical site infection on 3 November 2016, and there are inconsistencies in the interpretation of evidence and recommendations in existing national guidelines. These new WHO guidelines are valid for any country and suitable to local adaptations, and take account of the strength of available scientific evidence, the cost and resource implications, and patient values and preferences.