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Multi-Layered Transcription

Author : Müller, Nicole
Publisher : Plural Publishing
ISBN 13 : 1597568708
Total Pages : 190 pages
Book Rating : 4.5/5 (975 download)

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Book Synopsis Multi-Layered Transcription by : Müller, Nicole

Download or read book Multi-Layered Transcription written by Müller, Nicole and published by Plural Publishing. This book was released on 2005-11-01 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as a course in the phonetic transcription of normal and disordered speech. What differentiates this book from existing approaches to phonetic transcription and conversational analysis is that it concentrates on linking together layers of detail to result in a complete record for the entire range of transcribable behaviors. Müller's book represents the first attempt to amalgamate differing methods to give phoneticians and clinicians a transcriptional tool kit, thus allowing them to generate a rich description of their data. This approach results in a variety of layers of transcription, all or some of which are available to the clinician or researcher faced with the task of transcribing speech. The layers include a base, orthographic layer; segmental and suprasegmental phonetic layers; a gaze and gesture layer; a layer for marking aspects of discourse (e.g., overlap); and finally, a layer for highlighting behaviors of specific clinical interest (e.g., stuttering behavior). This book clearly lays out the various layers of transcription in this approach, illustrating them with normal and clinical data as well as exercises for the reader. Each chapter in the book addresses a different layer of transcription, with a final chapter illustrating how to bring the layers together. Worked examples accompany each chapter, and appendices provide a quick reference to symbols and transcription conventions. Clinicians who need to transcribe speech samples for diagnosing disorders, planning treatment, and measuring treatment efficacy milestones will value that added precision available from use of the upgraded transcription techniques elucidated in this book.

Computational Genomics with R

Author : Altuna Akalin
Publisher : CRC Press
ISBN 13 : 1498781861
Total Pages : 463 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Computational Genomics with R by : Altuna Akalin

Download or read book Computational Genomics with R written by Altuna Akalin and published by CRC Press. This book was released on 2020-12-16 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.

Systems Biology of Transcription Regulation

Author : Ekaterina Shelest
Publisher : Frontiers Media SA
ISBN 13 : 2889199673
Total Pages : 191 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Systems Biology of Transcription Regulation by : Ekaterina Shelest

Download or read book Systems Biology of Transcription Regulation written by Ekaterina Shelest and published by Frontiers Media SA. This book was released on 2016-09-09 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcription regulation is a complex process that can be considered and investigated from different perspectives. Traditionally and due to technical reasons (including the evolution of our understanding of the underlying processes) the main focus of the research was made on the regulation of expression through transcription factors (TFs), the proteins directly binding to DNA. On the other hand, intensive research is going on in the field of chromatin structure, remodeling and its involvement in the regulation. Whatever direction we select, we can speak about several levels of regulation. For instance, concentrating on TFs, we should consider multiple regulatory layers, starting with signaling pathways and ending up with the TF binding sites in the promoters and other regulatory regions. However, it is obvious that the TF regulation, also including the upstream processes, represents a modest portion of all processes leading to gene expression. For more comprehensive description of the gene regulation, we need a systematic and holistic view, which brings us to the importance of systems biology approaches. Advances in methodology, especially in high-throughput methods, result in an ever-growing mass of data, which in many cases is still waiting for appropriate consideration. Moreover, the accumulation of data is going faster than the development of algorithms for their systematic evaluation. Data and methods integration is indispensable for the acquiring a systematic as well as a systemic view. In addition to the huge amount of molecular or genetic components of a biological system, the even larger number of their interactions constitutes the enormous complexity of processes occurring in a living cell (organ, organism). In systems biology, these interactions are represented by networks. Transcriptional or, more generally, gene regulatory networks are being generated from experimental ChIPseq data, by reverse engineering from transcriptomics data, or from computational predictions of transcription factor (TF) – target gene relations. While transcriptional networks are now available for many biological systems, mathematical models to simulate their dynamic behavior have been successfully developed for metabolic and, to some extent, for signaling networks, but relatively rarely for gene regulatory networks. Systems biology approaches provide new perspectives that raise new questions. Some of them address methodological problems, others arise from the newly obtained understanding of the data. These open questions and problems are also a subject of this Research Topic.

A Practical Handbook of Corpus Linguistics

Author : Magali Paquot
Publisher : Springer Nature
ISBN 13 : 3030462161
Total Pages : 686 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis A Practical Handbook of Corpus Linguistics by : Magali Paquot

Download or read book A Practical Handbook of Corpus Linguistics written by Magali Paquot and published by Springer Nature. This book was released on 2021-05-04 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is a comprehensive practical resource on corpus linguistics. It features a range of basic and advanced approaches, methods and techniques in corpus linguistics, from corpus compilation principles to quantitative data analyses. The Handbook is organized in six Parts. Parts I to III feature chapters that discuss key issues and the know-how related to various topics around corpus design, methods and corpus types. Parts IV-V aim to offer a user-friendly introduction to the quantitative analysis of corpus data: for each statistical technique discussed, chapters provide a practical guide with R and come with supplementary online material. Part VI focuses on how to write a corpus linguistic paper and how to meta-analyze corpus linguistic research. The volume can serve as a course book as well as for individual study. It will be an essential reading for students of corpus linguistics as well as experienced researchers who want to expand their knowledge of the field.

Epigenetic Mechanisms of Gene Regulation

Author : Vincenzo E. A. Russo
Publisher :
ISBN 13 :
Total Pages : 716 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Epigenetic Mechanisms of Gene Regulation by : Vincenzo E. A. Russo

Download or read book Epigenetic Mechanisms of Gene Regulation written by Vincenzo E. A. Russo and published by . This book was released on 1996 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.

Phonetic Transcription in Theory and Practice

Author : Barry Heselwood
Publisher : Edinburgh University Press
ISBN 13 : 0748691014
Total Pages : 224 pages
Book Rating : 4.7/5 (486 download)

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Book Synopsis Phonetic Transcription in Theory and Practice by : Barry Heselwood

Download or read book Phonetic Transcription in Theory and Practice written by Barry Heselwood and published by Edinburgh University Press. This book was released on 2013-10-24 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phonetic transcription is a key element in many kinds of written works, not least linguistics books, dictionaries, language-teaching texts and bilingual reference works. This book is the first book-length scholarly monograph to address all of the important aspects of phonetic transcription.The aim of phonetic transcription is to represent the sounds of speech on paper. This book reviews contemporary uses of phonetic transcription in dictionaries, language teaching texts, phonetic and phonological studies, dialectology and sociolinguistics, speech pathology and therapy, and forensic phonetics. Heselwood surveys the history of attempts to represent speech, considering the relationship of transcription to written language. The book also includes a thorough analysis of the many different kinds of phonetic transcription - broad, narrow, auditory, systematic, segmental, suprasegmental, parametric and others - addressing what exactly is represented in different kinds and levels of transcription.Different ways in which transcription can be used alongside modern instrumental records of speech are illustrated with the claim that transcription embodies a kind of knowledge about speech unavailable to instruments - knowledge gained from the experience of listening to it in a phonetically informed manner. The author grounds this claim in the philosophy of phenomenalism, countering arguments against auditory transcription that have been advanced by experimental phoneticians for reasons of empirical inadequacy, and by linguistic rationalists who say it is irrelevant for understanding the supposedly innate categories that are said to underlie speech. A glossary of terms is included, along with a series of examples to demonstrate the comparison, classification and interpretation of phonetic transcriptions for different purposes.

Manual of Clinical Phonetics

Author : Martin J. Ball
Publisher : Routledge
ISBN 13 : 1000334406
Total Pages : 570 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Manual of Clinical Phonetics by : Martin J. Ball

Download or read book Manual of Clinical Phonetics written by Martin J. Ball and published by Routledge. This book was released on 2021-04-11 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive collection equips readers with a state-of-the-art description of clinical phonetics and a practical guide on how to employ phonetic techniques in disordered speech analysis. Divided into four sections, the manual covers the foundations of phonetics, sociophonetic variation and its clinical application, clinical phonetic transcription, and instrumental approaches to the description of disordered speech. The book offers in-depth analysis of the instrumentation used in articulatory, auditory, perceptual, and acoustic phonetics and provides clear instruction on how to use the equipment for each technique as well as a critical discussion of how these techniques have been used in studies of speech disorders. With fascinating topics such as multilingual sources of phonetic variation, principles of phonetic transcription, speech recognition and synthesis, and statistical analysis of phonetic data, this is the essential companion for students and professionals of phonetics, phonology, language acquisition, clinical linguistics, and communication sciences and disorders.

Systems Biology of Transcription Regulation

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Systems Biology of Transcription Regulation by :

Download or read book Systems Biology of Transcription Regulation written by and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcription regulation is a complex process that can be considered and investigated from different perspectives. Traditionally and due to technical reasons (including the evolution of our understanding of the underlying processes) the main focus of the research was made on the regulation of expression through transcription factors (TFs), the proteins directly binding to DNA. On the other hand, intensive research is going on in the field of chromatin structure, remodeling and its involvement in the regulation. Whatever direction we select, we can speak about several levels of regulation. For instance, concentrating on TFs, we should consider multiple regulatory layers, starting with signaling pathways and ending up with the TF binding sites in the promoters and other regulatory regions. However, it is obvious that the TF regulation, also including the upstream processes, represents a modest portion of all processes leading to gene expression. For more comprehensive description of the gene regulation, we need a systematic and holistic view, which brings us to the importance of systems biology approaches. Advances in methodology, especially in high-throughput methods, result in an ever-growing mass of data, which in many cases is still waiting for appropriate consideration. Moreover, the accumulation of data is going faster than the development of algorithms for their systematic evaluation. Data and methods integration is indispensable for the acquiring a systematic as well as a systemic view. In addition to the huge amount of molecular or genetic components of a biological system, the even larger number of their interactions constitutes the enormous complexity of processes occurring in a living cell (organ, organism). In systems biology, these interactions are represented by networks. Transcriptional or, more generally, gene regulatory networks are being generated from experimental ChIPseq data, by reverse engineering from transcriptomics data, or from computational predictions of transcription factor (TF) - target gene relations. While transcriptional networks are now available for many biological systems, mathematical models to simulate their dynamic behavior have been successfully developed for metabolic and, to some extent, for signaling networks, but relatively rarely for gene regulatory networks. Systems biology approaches provide new perspectives that raise new questions. Some of them address methodological problems, others arise from the newly obtained understanding of the data. These open questions and problems are also a subject of this Research Topic.

Surgical Research

Author : Wiley W. Souba
Publisher : Academic Press
ISBN 13 : 9780126553307
Total Pages : 1526 pages
Book Rating : 4.5/5 (533 download)

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Book Synopsis Surgical Research by : Wiley W. Souba

Download or read book Surgical Research written by Wiley W. Souba and published by Academic Press. This book was released on 2001-01-25 with total page 1526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributors. -- Foreword. -- Preface. -- Getting Started. -- Assessing Available Information. -- Organizing and Preliminary Planning for Surgical Research -- Writing a Protocol: Animals, Humans, and Use of Biologic, Chemical, and Radiologic Agents. -- Grantsmanship. -- Informed Consent and the Protection of Human Research Subjects: Historical Perspectives and Guide to Current United States Regulations. -- Animal Care and Maintenance. -- Funding Strategies and Agencies: Academic-Industrial Relationships; Intellectual Property. -- Statistical Considerations. -- Use of Nonexperimental Studies to Evaluate Surgical Procedures and Other Interventions: The Challenge of Risk Adjustment. -- Measuring Surgical Outcomes. -- Design of Clinical Trials. -- Using Administrative Data for Clinical Research. -- Research in the Intensive Care Unit: Ethical and Methodological Issues. -- Research in the Operating Room. -- Effects of Age and Gender. -- Strategies, Principles, and Techniques Using Transgeni ...

Complex Networks and Their Applications XI

Author : Hocine Cherifi
Publisher : Springer Nature
ISBN 13 : 3031211278
Total Pages : 667 pages
Book Rating : 4.0/5 (312 download)

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Book Synopsis Complex Networks and Their Applications XI by : Hocine Cherifi

Download or read book Complex Networks and Their Applications XI written by Hocine Cherifi and published by Springer Nature. This book was released on 2023-01-03 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights cutting-edge research in the field of network science, offering scientists, researchers, students, and practitioners a unique update on the latest advances in theory and a multitude of applications. It presents the peer-reviewed proceedings of the XI International Conference on Complex Networks and their Applications (COMPLEX NETWORKS 2022). The carefully selected papers cover a wide range of theoretical topics such as network models and measures; community structure, network dynamics; diffusion, epidemics, and spreading processes; resilience and control as well as all the main network applications, including social and political networks; networks in finance and economics; biological and neuroscience networks and technological networks.

The Routledge Handbook of Applied Linguistics

Author : James Simpson
Publisher : Routledge
ISBN 13 : 1136857974
Total Pages : 951 pages
Book Rating : 4.1/5 (368 download)

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Book Synopsis The Routledge Handbook of Applied Linguistics by : James Simpson

Download or read book The Routledge Handbook of Applied Linguistics written by James Simpson and published by Routledge. This book was released on 2011-03-15 with total page 951 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Routledge Handbook of Applied Linguistics serves as an introduction and reference point to key areas in the field of applied linguistics. The five sections of the volume encompass a wide range of topics from a variety of perspectives: applied linguistics in action language learning, language education language, culture and identity perspectives on language in use descriptions of language for applied linguistics. The forty-seven chapters connect knowledge about language to decision-making in the real world. The volume as a whole highlights the role of applied linguistics, which is to make insights drawn from language study relevant to such decision-making. The chapters are written by specialists from around the world. Each one provides an overview of the history of the topic, the main current issues and possible future trajectory. Where appropriate, authors discuss the impact and use of new technology in the area. Suggestions for further reading are provided with every chapter. The Routledge Handbook of Applied Linguistics is an essential purchase for postgraduate students of applied linguistics. Editorial board: Ronald Carter, Guy Cook, Diane Larsen-Freeman and Amy Tsui.

Research Methods in Clinical Linguistics and Phonetics

Author : Nicole Müller
Publisher : John Wiley & Sons
ISBN 13 : 1118349679
Total Pages : 338 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Research Methods in Clinical Linguistics and Phonetics by : Nicole Müller

Download or read book Research Methods in Clinical Linguistics and Phonetics written by Nicole Müller and published by John Wiley & Sons. This book was released on 2013-10-24 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Methods in Clinical Linguistics and Phonetics GUIDES TO RESEARCH METHODS IN LANGUAGE AND LINGUISTICS “Up to date and covering a refreshingly wide range of approaches, this is a first-rate guide and resource for both practitioners and consumers of research in clinical linguistics and phonetics.” Mick Perkins, University of Sheffield “This truly outstanding collection of readings, treating a number of critical issues with great clarity, is certain to be quickly recognized as a valuable resource by the community of researchers.” Martin R. Gitterman, The City University of New York Research Methods in Clinical Linguistics and Phonetics introduces a wide range of research philosophies, methods, and tools used across linguistics, phonetics, and speech science, as applied to disordered speech and language. Comprised of sixteen chapters, each authored by specialists representing a variety of approaches, the volume addresses core topics for students `undertaking their own research, including: experimental and quasi-experimental methods qualitative methods, including ethnography and conversation analysis sociolinguistics corpus construction and analysis data recording, transcription, and digital analysis of speech In addition to exploring these and other topics, the volume considers the research ethics associated with working with those who have speech or other communication difficulties. There is a detailed discussion of the dissemination of research results in the form of theses, dissertations, and journal articles, and of the peer review process. Chapters include summary boxes to highlight salient information, and resources for researchers such as relevant web archives and tools. It offers students and researchers from a variety of entry points – such as linguistics, education, psychology, and speech pathology – an introduction to the scope of research in clinical linguistics and phonetics, and a practical guide to this interdisciplinary field.

Mechanisms in Transcriptional Regulation

Author : Albert J. Courey
Publisher : John Wiley & Sons
ISBN 13 : 1444300458
Total Pages : 248 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Mechanisms in Transcriptional Regulation by : Albert J. Courey

Download or read book Mechanisms in Transcriptional Regulation written by Albert J. Courey and published by John Wiley & Sons. This book was released on 2009-01-22 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms in Transcriptional Regulation provides a concisediscussion of the fundamental concepts in transcription and itsregulation. Covers RNA polymerases, transcriptional machinery, mechanismsof transcriptional activation, the histone code hypothesis, theepigenetic control of transcription, and combinatorial control insignaling and development Features over 80 figures available to download online Chapters include comprehensive reading lists, boxeshighlighting theoretical concepts and experimental methods andproblems designed to build and test understanding

Foundations of Pragmatics

Author : Wolfram Bublitz
Publisher : Walter de Gruyter
ISBN 13 : 3110214253
Total Pages : 725 pages
Book Rating : 4.1/5 (12 download)

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Book Synopsis Foundations of Pragmatics by : Wolfram Bublitz

Download or read book Foundations of Pragmatics written by Wolfram Bublitz and published by Walter de Gruyter. This book was released on 2011 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: Opening the 9-volume-series Handbooks of Pragmatics, this handbook provides a comprehensive overview of the foundations of pragmatics. It covers the central theories as well as concepts and topics characteristic of mainstream pragmatics, i.e. the most widespread approach to the ways and means of using language in authentic social contexts. The articles provide both state of the art reviews and critical evaluations of research in pragmatics. Topics are thus not only considered within their scholarly context but are also critically evaluated from current perspectives.

Predicting Transcription Factor Complexes

Author : Thorsten Will
Publisher : Springer
ISBN 13 : 3658082690
Total Pages : 155 pages
Book Rating : 4.6/5 (58 download)

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Book Synopsis Predicting Transcription Factor Complexes by : Thorsten Will

Download or read book Predicting Transcription Factor Complexes written by Thorsten Will and published by Springer. This book was released on 2014-12-05 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: In his master thesis Thorsten Will proposes the substantial information content of protein complexes involving transcription factors in the context of gene regulatory networks, designs the first computational approaches to predict such complexes as well as their regulatory function and verifies the practicability using data of the well-studied yeast S.cereviseae. The novel insights offer extensive capabilities towards a better understanding of the combinatorial control driving transcriptional regulation.

A Qualitative Approach to the Validation of Oral Language Tests

Author : Anne Lazaraton
Publisher : Cambridge University Press
ISBN 13 : 0521002672
Total Pages : 241 pages
Book Rating : 4.5/5 (21 download)

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Book Synopsis A Qualitative Approach to the Validation of Oral Language Tests by : Anne Lazaraton

Download or read book A Qualitative Approach to the Validation of Oral Language Tests written by Anne Lazaraton and published by Cambridge University Press. This book was released on 2002-07-18 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide language testers with a background in the conversation analytic framework.

Transcription

Author : William M. Brown
Publisher : CRC Press
ISBN 13 : 9780415271998
Total Pages : 172 pages
Book Rating : 4.2/5 (719 download)

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Book Synopsis Transcription by : William M. Brown

Download or read book Transcription written by William M. Brown and published by CRC Press. This book was released on 2001-09-20 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of transcription has moved forward at a furious pace over recent years, and an understanding of the processes involved in gene regulation and expression has become an essential element in biochemistry, genome biology, molecular biology and molecular genetics. In this timely book, the authors present an accessible, yet comprehensive, coverage suitable for students at a senior undergraduate level, and for postgraduates needing an overview of the current state of play. It covers a number of pertinent examples of transcription systems for eukaryotes and prokaryotes, indicates methods for studying transcription, and surveys the whole topic of transcription from many perspectives.