Motor Neuron Disease Research Progress

Download Motor Neuron Disease Research Progress full books in PDF, epub, and Kindle. Read online Motor Neuron Disease Research Progress ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Motor Neuron Disease Research Progress

Author : Raffaele L. Mancini
Publisher : Nova Publishers
ISBN 13 : 9781604561555
Total Pages : 330 pages
Book Rating : 4.5/5 (615 download)

DOWNLOAD NOW!

Book Synopsis Motor Neuron Disease Research Progress by : Raffaele L. Mancini

Download or read book Motor Neuron Disease Research Progress written by Raffaele L. Mancini and published by Nova Publishers. This book was released on 2008 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: The motor neuron diseases (or motor neuron diseases) (MND) are a group of progressive neurological disorders that destroy motor neurons, the cells that control voluntary muscle activity such as speaking, walking, breathing, and swallowing. Neurological examination presents specific signs associated with upper and lower motor neuron degeneration. Signs of upper motor neuron damage include spasticity, brisk reflexes and the Babinski sign. Signs of lower motor neuron damage include weakness and muscle atrophy. Every muscle group in the body requires both upper and lower motor neurons to function. It is a common misconception that "upper" motor neurons control the arms, while "lower" motor neurons control the legs. The signs described above can occur in any muscle group, including the arms, legs, torso, and bulbar region. Symptoms usually present between the ages of 50-70, and include progressive weakness, muscle wasting, and muscle fasciculations; spasticity or stiffness in the arms and legs; and overactive tendon reflexes. Patients may present with symptoms as diverse as a dragging foot, unilateral muscle wasting in the hands, or slurred speech. This new book presents the latest research from around the globe.

Molecular and Cellular Therapies for Motor Neuron Diseases

Author : Nicholas M Boulis
Publisher : Academic Press
ISBN 13 : 0128025247
Total Pages : 337 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Molecular and Cellular Therapies for Motor Neuron Diseases by : Nicholas M Boulis

Download or read book Molecular and Cellular Therapies for Motor Neuron Diseases written by Nicholas M Boulis and published by Academic Press. This book was released on 2017-01-18 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials. Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy

Research Progress in Motor Neurone Disease

Author : Frank Clifford Rose
Publisher :
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Research Progress in Motor Neurone Disease by : Frank Clifford Rose

Download or read book Research Progress in Motor Neurone Disease written by Frank Clifford Rose and published by . This book was released on 1984 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Novel Aspects on Motor Neuron Disease

Author : Humberto Foyaca Sibat
Publisher : BoD – Books on Demand
ISBN 13 : 183880773X
Total Pages : 120 pages
Book Rating : 4.8/5 (388 download)

DOWNLOAD NOW!

Book Synopsis Novel Aspects on Motor Neuron Disease by : Humberto Foyaca Sibat

Download or read book Novel Aspects on Motor Neuron Disease written by Humberto Foyaca Sibat and published by BoD – Books on Demand. This book was released on 2020-05-20 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dedicated to our readers, we include novel information (not reported in IntechOpen’s books before) about new contributions of aberrant astrocytes to MND damage and death in the SOD1G93A rat experimental model of ALS; novel genetic studies on ALS; an update of the structural and functional consequences of the spinal muscular atrophy-linked mutations of the survival motor neuron protein; stem cell therapy for MND; and the novel treatment for SMA and ALS in the introductory chapter. This book contains selected peer-reviewed chapters written by international researchers. In this publication, the readers will find a compilation of state-of-the-art reviews about etiology, therapies, investigations, the molecular basis of disease progression and clinical manifestations, and the genetic familial ALS, as well as novel therapeutic modalities. We look forward with confidence and pride to the remarkable role that this book will play for a new vision and mission.

Progress in Neurological Research, with Particular Reference to Motor Neurone Disease

Author : Peter O. Behan
Publisher :
ISBN 13 : 9780272795132
Total Pages : 232 pages
Book Rating : 4.7/5 (951 download)

DOWNLOAD NOW!

Book Synopsis Progress in Neurological Research, with Particular Reference to Motor Neurone Disease by : Peter O. Behan

Download or read book Progress in Neurological Research, with Particular Reference to Motor Neurone Disease written by Peter O. Behan and published by . This book was released on 1979-01-01 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Motor Neuron Disease

Author : P.N. Leigh
Publisher : Springer Science & Business Media
ISBN 13 : 1447118715
Total Pages : 477 pages
Book Rating : 4.4/5 (471 download)

DOWNLOAD NOW!

Book Synopsis Motor Neuron Disease by : P.N. Leigh

Download or read book Motor Neuron Disease written by P.N. Leigh and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND.

Palliative Care in Amyotrophic Lateral Sclerosis

Author : David Oliver
Publisher : OUP Oxford
ISBN 13 : 0191509507
Total Pages : 353 pages
Book Rating : 4.1/5 (915 download)

DOWNLOAD NOW!

Book Synopsis Palliative Care in Amyotrophic Lateral Sclerosis by : David Oliver

Download or read book Palliative Care in Amyotrophic Lateral Sclerosis written by David Oliver and published by OUP Oxford. This book was released on 2014-03-20 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amytrophic Lateral Sclerosis (ALS or motor neurone disease) is a progressive neurodegenerative disease that can cause profound suffering for both the patient and their family. Whilst new treatments for ALS are being developed, these are not curative and offer only the potential to slow its progression. Palliative care must therefore be integral to the clinical approach to the disease. Palliative Care in Amyotrophic Lateral Sclerosis: From diagnosis to bereavement reflects the wide scope of this care; it must cover not just the terminal phase, but support the patient and their family from the onset of the disease. Both the multidisciplinary palliative care team and the neurology team are essential in providing a high standard of care and allowing quality of life (both patient and carer) to be maintained. Clear guidelines are provided to address care throughout the disease process. Control of symptoms is covered alongside the psychosocial care of patients and their families. Case studies are used to emphasise the complexity of the care needs and involvement of the patient and family, culminating in discussion of bereavement. Different models of care are explored, and this new edition utilizes the increase in both the evidence-base and available literature on the subject. New topics discussed include complementary therapies, personal and family experiences of ALS, new genetics research, and updated guidelines for patient care, to ensure this new edition remains the essential guide to palliative care in ALS.

Motor Neuron Disease in Adults

Author : Mark B. Bromberg
Publisher : Contemporary Neurology
ISBN 13 : 019978311X
Total Pages : 369 pages
Book Rating : 4.1/5 (997 download)

DOWNLOAD NOW!

Book Synopsis Motor Neuron Disease in Adults by : Mark B. Bromberg

Download or read book Motor Neuron Disease in Adults written by Mark B. Bromberg and published by Contemporary Neurology. This book was released on 2014-10-28 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Motor Neuron Disease in Adults' reviews new information from 1998 as it applies to all aspects of motor neuron disease. Articles included use evidence-based methods to ensure that the new information is solid and advances the topic. The book can be used by anyone who provides any type of care to ALS patients.

The Management of Motor Neurone Disease

Author : George M. Cochrane
Publisher :
ISBN 13 :
Total Pages : 124 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis The Management of Motor Neurone Disease by : George M. Cochrane

Download or read book The Management of Motor Neurone Disease written by George M. Cochrane and published by . This book was released on 1987 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Motor Neuron Disease: New Insights for the Healthcare Professional: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464904448
Total Pages : 61 pages
Book Rating : 4.4/5 (649 download)

DOWNLOAD NOW!

Book Synopsis Motor Neuron Disease: New Insights for the Healthcare Professional: 2011 Edition by :

Download or read book Motor Neuron Disease: New Insights for the Healthcare Professional: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motor Neuron Disease: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Motor Neuron Disease in a concise format. The editors have built Motor Neuron Disease: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Motor Neuron Disease in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Motor Neuron Disease: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Amyotrophic Lateral Sclerosis

Author : Imaharu Nakano
Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 428 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Amyotrophic Lateral Sclerosis by : Imaharu Nakano

Download or read book Amyotrophic Lateral Sclerosis written by Imaharu Nakano and published by Elsevier Science & Technology. This book was released on 1996 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. Rapid progress has been made in both the research and clinical aspects of amyotrophic lateral sclerosis (ALS). There are striking achievements in many areas of ALS research.The contents of this volume will allow the reader to easily understand this progress, finding exciting advances in every section that could not have been imagined several years ago. This volume will bring great benefits to all researchers and clinicians involved with amyotrophic lateral sclerosis.

Amyotrophic Lateral Sclerosis

Author : V. Cosi
Publisher : Springer Science & Business Media
ISBN 13 : 1468453025
Total Pages : 341 pages
Book Rating : 4.4/5 (684 download)

DOWNLOAD NOW!

Book Synopsis Amyotrophic Lateral Sclerosis by : V. Cosi

Download or read book Amyotrophic Lateral Sclerosis written by V. Cosi and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: An International Conference on "Therapeutic. Psychological and Research Aspects of Amyotrophic Lateral Sclerosis" was held in Varese. Italy from the 27th to the 31st March 1985. Health care professionals. scientists. patients and their families from twenty countries around the world participated in this meeting. The objectives of the Varese conference were the following: a. To provide a forum for the proponents of the various paths of research into ALS. b. To correlate the useful therapies employed regionally. for the purpose of developing a common guide for patients, families, and supporting professionals. c. To encourage self-examination by the health care professionals into the psychological barriers imposed by a diagnosis of terminal illness for which there is no known cause or cure. Not surprisingly, there were no announcements of "breakthroughs" or "miracle cures", which are nonetheless hoped for in the confrontation of a disease such as ALS. It is fair to say, however, that Varese provided the context for a thorough review of what is known about ALS and we hope that the papers will renew some of the enthusiasm which has characterized this conference. The book contains six sections: Basic Research Aspects, Diagnostic Tools, Clinical Management, Therapeutic Trials, Psychological Aspects and the Epidemiology of ALS. Certain aspects, such as pathological studies and animal models, have not been covered; these subjects were partially treated during the informal sessions. Nevertheless, the large number of papers bears evidence to the growing interest in ALS and to the success of the Varese meeting.

Clinical and Molecular Aspects of Motor Neuron Disease

Author : Johnathan Cooper-Knock
Publisher : Morgan & Claypool
ISBN 13 : 9781615044283
Total Pages : 62 pages
Book Rating : 4.0/5 (442 download)

DOWNLOAD NOW!

Book Synopsis Clinical and Molecular Aspects of Motor Neuron Disease by : Johnathan Cooper-Knock

Download or read book Clinical and Molecular Aspects of Motor Neuron Disease written by Johnathan Cooper-Knock and published by Morgan & Claypool. This book was released on 2013-09-01 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this e-book, motor neuron disease (MND) shall refer to amyotrophic lateral sclerosis (ALS), the most common neurodegenerative disorder affecting both the upper and lower motor neurons. With the discovery of C9ORF72 expansions in approximately 10% of all MND cases, in certain populations, we stand at the brink of a new era of MND research and hopefully treatment facilitated by the ability to associate a relatively large group of patients with a similar disease mechanism. This review will summarise both current clinical management of MND and our present understanding of the molecular pathogenesis of MND. Study of C9ORF72-MND has the potential to rapidly advance both of these aspects in the coming years. In the first section, we will discuss the clinical features of MND and describe how patients with this devastating condition present, are investigated, and managed in the 21st century. Although, currently, management is limited by an incomplete understanding of disease pathophysiology, there is much which can be done to assist and support patients with MND. In the following sections, we will discuss molecular mechanisms implicated in MND, highlighting observations which unify different theories. Particular attention will be given to placing proposed mechanisms within the clinical course of MND. Furthermore, novel therapeutic targets will be discussed. Table of Contents: Clinical Aspects of MND / Molecular Aspects of MND / References / Author Biographies / Titles of Related Interest / Series of Related Interest

The Mnd Diet

Author : Lynne D. M. Noble
Publisher : Independently Published
ISBN 13 : 9781729472897
Total Pages : 118 pages
Book Rating : 4.4/5 (728 download)

DOWNLOAD NOW!

Book Synopsis The Mnd Diet by : Lynne D. M. Noble

Download or read book The Mnd Diet written by Lynne D. M. Noble and published by Independently Published. This book was released on 2018-10-31 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies have shown that the upregulation of T cells helps slow down the rate of progression of motor neuron disease so what should we eat to increase this type of immune cell? What nutrients are particularly beneficial for brain health?. Coffee has been shown to slow down the rate of progression but why? People who tend to engage in heavy exercise are at a higher risk of being diagnosed with MND. What are some of the underlying processes at work here? Can axons regenerate once damaged or is the damage irreversible? Which common medications can produce ALS type symptoms. The answers to these and many more questions are answered using the latest research and draw on a number of disciplines. While the book particularly focuses on motor neuron disease, it provides lots of useful information which can be applied to most neurodegenerative conditions including multiple sclerosis, Parkinson's disease and the dementias.

Motor Neurone Disease

Author :
Publisher : Elsevier
ISBN 13 : 0443141169
Total Pages : 548 pages
Book Rating : 4.4/5 (431 download)

DOWNLOAD NOW!

Book Synopsis Motor Neurone Disease by :

Download or read book Motor Neurone Disease written by and published by Elsevier. This book was released on 2024-05-31 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motor Neurone Disease, Volume 176 in the International Review in Neurobiology serial highlights new advances, with this new volume presenting interesting chapters written by an international board of authors. Updates include chapters on Clinical features, differential diagnosis and pathology, Recent advances in genetics of familial and sporadic ALS, Non-coding genome contribution to ALS, Contribution of neurophysiology to the diagnosis and monitoring ALS, Advances in symptom management and monitoring disease progression, Use of biomarkers in clinical trials and future developments that will help identify new biomarkers, Application of systems biology to identify therapeutic targets, and much more. Additional sections cover Evidence of mitochondrial dysfunction (in ALS) and how to measure it in model systems, Current neuroprotective therapies and future prospects, The role of glial cells in ALS, Dysregulation of RNA biology in ALS, New developments in pre-clinical models of ALS to guide translation.

Spectrums of Amyotrophic Lateral Sclerosis

Author : Christopher A. Shaw
Publisher : John Wiley & Sons
ISBN 13 : 1119745500
Total Pages : 240 pages
Book Rating : 4.1/5 (197 download)

DOWNLOAD NOW!

Book Synopsis Spectrums of Amyotrophic Lateral Sclerosis by : Christopher A. Shaw

Download or read book Spectrums of Amyotrophic Lateral Sclerosis written by Christopher A. Shaw and published by John Wiley & Sons. This book was released on 2021-04-20 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: SPECTRUMS OF AMYOTROPHIC LATERAL SCLEROSIS Discover state-of-the-art research findings on ALS from leading authors and editors in the field In Spectrums of Amyotrophic Lateral Sclerosis: Heterogeneity, Pathogenesis & Therapeutic Directions, distinguished researchers and editors Dr. Christopher A. Shaw and Jessica R. Morrice deliver a practical and powerful perspective on Amyotrophic Lateral Sclerosis (ALS) as a heterogeneous spectrum of disorders. This increasingly accepted point-of-view allows researchers and medical professionals to develop better targeted interventions and more precise therapies. In the book, readers will find chapters on a wide variety of critical issues facing ALS researchers and healthcare practitioners treating ALS sufferers, including animal models of ALS, neuronal support cells known to have a pivotal role in ALS, and current challenges in ALS clinical trials, among others. The authors describe pathologic features common to all cases of ALS and why animal models, though crucial, should be interpreted with caution. Finally, multiple genetic and environmental etiologies of the disease are discussed. Readers will also benefit from the inclusion of: A thorough introduction to ALS as a spectrum disease and the implications for models, therapeutic development and clinical trial design Explorations of the genetic basis of ALS, prospective sALS etiologies, and the involvement of microbiome in ALS Discussions of ALS-PDC and environmental risk factors, protein aggregation in ALS, defects in RNA metabolism in ALS, and the non-cell autonomous nature of ALS and the involvement of glial cells Examinations of animal models of ALS and perspectives on previously failed ALS therapeutics and current therapeutic strategies Perfect for clinical neurologists, healthcare providers and caretakers, clinicians, and researchers studying motor neuron disease, Spectrums of Amyotrophic Lateral Sclerosis: Heterogeneity, Pathogenesis & Therapeutic Directions is also an indispensable resource for the neurodegenerative research community, neurology residents, and graduate-level neuroscience students.

Practical Guide to Neurogenetics E-Book

Author : Thomas T. Warner
Publisher : Elsevier Health Sciences
ISBN 13 : 0702038458
Total Pages : 343 pages
Book Rating : 4.7/5 (2 download)

DOWNLOAD NOW!

Book Synopsis Practical Guide to Neurogenetics E-Book by : Thomas T. Warner

Download or read book Practical Guide to Neurogenetics E-Book written by Thomas T. Warner and published by Elsevier Health Sciences. This book was released on 2008-11-04 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: This simple guide to neurogenetics demystifies the overwhelming amount of information on the subject so you can identify key clinical features and understand your management options. Reach relevant differential diagnoses and provide appropriate counseling to your patients using the symptom-based approach. By integrating genetic and neurological approaches to diagnoses, this book ensures that the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis are clear and explicit. Concise and portable, this book is ideal for easy reference in clinical use. Details the underlying basic science and clinical features of genetic disorders by taking a symptom-based approach to provide you with a comprehensive understanding of the field. Focuses on the clinical application of neurogenetics to be of practical use to you in the clinic. Clarifies the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis by integrating genetic and neurological approaches to diagnoses. Discusses and evaluates necessary investigations so you know when to use them and when to refer. Highlights diagnostic and therapeutic tips so you can learn new concepts or refine your skills in practice. Refers to online sources, such as Online Mendelian Inheritance in Man (OMIM) and others, to help you supplement your knowledge.