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Author :
Publisher : Springer
ISBN 13 : 9789400749375
Total Pages : 130 pages
Book Rating : 4.7/5 (493 download)
Download or read book Morphofunctional Aspects of Tumor Microcirculation written by and published by Springer. This book was released on 2012-09-30 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Domenico Ribatti
Publisher : Springer Science & Business Media
ISBN 13 : 9400749368
Total Pages : 122 pages
Book Rating : 4.4/5 (7 download)
Download or read book Morphofunctional Aspects of Tumor Microcirculation written by Domenico Ribatti and published by Springer Science & Business Media. This book was released on 2012-09-28 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood vessels of tumors display many structural and functional abnormalities. Their unusual leakiness, potential for rapid growth and remodeling, and expression of distinctive surface molecules mediate the dissemination of tumor cells in the bloodstream and maintain the tumor microenvironment. Like normal blood vessels, they consist of endothelial cells, mural cells and their enveloping basement membrane. Common features, irrespective of their origin, size and growth pattern, are absent hierarchy, formation of large-caliber sinusoidal vessels, markedly heterogeneous density, increased permeability, decreased and abnormal pericyte-endothelial cell adhesion, irregular basement membrane structure, and the incorporation of bone-marrow-derived endothelial progenitor cells in the microvasculature. A number of specific tumor endothelial markers have been identified, as well as chromosomal abnormalities. These markers may be used to deliver drugs specifically and selectively to the tumor microvasculature.
Author : Domenico Ribatti
Publisher : Springer Science & Business Media
ISBN 13 : 940074935X
Total Pages : 122 pages
Book Rating : 4.4/5 (7 download)
Download or read book Morphofunctional Aspects of Tumor Microcirculation written by Domenico Ribatti and published by Springer Science & Business Media. This book was released on 2012-09-29 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes abnormalities in the blood vessels of tumors, identifying a number of specific tumor endothelial markers, as well as chromosomal abnormalities. Shows how these markers may be used to deliver drugs selectively to the tumor microvasculature.
Author : Domenico Ribatti
Publisher : Academic Press
ISBN 13 : 0128113294
Total Pages : 184 pages
Book Rating : 4.1/5 (281 download)
Download or read book Milestones in Immunology written by Domenico Ribatti and published by Academic Press. This book was released on 2017-06-13 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Milestones in Immunology: Based on Collected Papers contains scientific milestones relating to the history of medicine over the past two centuries. The book highlights the contributions of pioneering scientists whose discoveries have paved the way for researchers working in the field of immunology. As the science of immunology grew from knowledge that survivors of common infectious diseases rarely contracted them again, the book uses this as a central thesis, helping readers understand how the adaptive immune system aids in defense against pathogens. In addition, the book covers special fields, such as immunohistochemistry, immunogenetics and immunopathology. For the past century, immunology has fascinated and inspired some of the greatest scientists of our time. Numerous Nobel Prizes have been awarded for fundamental discoveries in immunology, from Paul Ehrlich' work on antibodies (1908) to the studies of Zinkernagel and Doherty (1986) elucidating mechanisms of cell-mediated immunity. - Provides on update on developments since the publication of Nobel prize winning research for fundamental discoveries in immunology - Discusses the changing theories and technologies that guided the field - Lists all the important discoveries and books in the field - Explains, in detail, the many Nobel prize-winning contributions of immunologists - Provides recognition of the scientists who were pioneers of landmark discoveries in immunology
Author : Alecsandru Ioan Baba
Publisher :
ISBN 13 : 9789732714577
Total Pages : 787 pages
Book Rating : 4.7/5 (145 download)
Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert Vink
Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author :
Publisher :
ISBN 13 :
Total Pages : 1148 pages
Book Rating : 4.3/5 (243 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1985 with total page 1148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kwang-Sup Soh
Publisher : Springer Science & Business Media
ISBN 13 : 1461406013
Total Pages : 327 pages
Book Rating : 4.4/5 (614 download)
Download or read book The Primo Vascular System written by Kwang-Sup Soh and published by Springer Science & Business Media. This book was released on 2011-11-03 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings from the first International Symposium on Primo Vascular System 2010 (ISPS 2010) with special topics on cancer and regeneration was held in Jecheon, Korea during September 17-18, 2010. Includes coverage of new study results that have better revealed the functional aspects of PVS, including its roles in the areas of regenerative medicine and cancer.
Author : Enrico Agabiti-Rosei
Publisher : Springer Nature
ISBN 13 : 3030478017
Total Pages : 215 pages
Book Rating : 4.0/5 (34 download)
Download or read book Microcirculation in Cardiovascular Diseases written by Enrico Agabiti-Rosei and published by Springer Nature. This book was released on 2020-10-03 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervention. A number of innovative areas of research are considered, including the role of the immune system, inflammation and oxidative stress in the development of microvascular alterations. Lastly, it examines the availability of recent non-invasive methods for the evaluation of small resistance artery morphology in the retina, which in the near future may provide a useful tool for the stratification of cardiovascular risk and even for clinical decisions regarding drug treatment, thus providing physicians with a clinically relevant instrument for improving and optimizing the management of hypertensive and diabetic patients. The book provides valuable, clinically relevant information for specialists (cardiology, internal medicine, and endocrinology) and general practitioners, and also offers novel and stimulating data to basic and clinical researchers.
Author : Werner A. Kaiser
Publisher : Springer Science & Business Media
ISBN 13 : 3540732926
Total Pages : 399 pages
Book Rating : 4.5/5 (47 download)
Download or read book Signs in MR-Mammography written by Werner A. Kaiser and published by Springer Science & Business Media. This book was released on 2008-11-27 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer is the leading cause of cancer-related deaths in women, and its prevalence has been steadily rising in recent decades. This book describes morphologic and kinetic signs that are important in the analysis of breast MR images before and after contrast administration and in various pulse sequences. It will help broaden the clinical application of MRM so that as many physicians as possible can make more accurate diagnoses.
Author : Orlando Catalano
Publisher : Springer Science & Business Media
ISBN 13 : 8847013550
Total Pages : 387 pages
Book Rating : 4.8/5 (47 download)
Download or read book Fundamentals in Oncologic Ultrasound written by Orlando Catalano and published by Springer Science & Business Media. This book was released on 2009-12-19 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a remarkable observation that human creativity can be fostered by spectacular scenery, itself usually the result of tectonic activity which raises mountains of beauty but carries the sting of earthquakes and eruptions. Think of Silicon Valley in Ca- fornia or of the Tokyo-Kyoto corridor in Eastern Japan. Another is the glorious Amalfi coast around Naples, where the authors of this new textbook work in the shadow of Mount Vesuvius. Is it the beauty that inspires or the tension of knowing that one’s life may be shattered at any moment if a volcanic or tectonic disaster strikes? Whatever the explanation, these authors’ passion for their subject shines through and their work carries not only their enthusiasm but also a rare beauty in its construction/format, for it is a joy to hold and behold with its beautiful all-colour printing and abundant illustrations of excellent quality, mainly, of course, ultrasound images but also corresponding CT scans and numerous elegant diagrams. But, is there a need for a textbook on ultrasound in oncology? Doesn’t everyone accept that CT or PET/CT (and sometimes MR) have nailed the problem of oncologic imaging? Well, while CT is undoubtedly the core imaging technique for the det- tion, staging, treatment planning and follow-up of tumours, there remain many app- cations for modern ultrasound, as readers of this textbook will be persuaded.
Author :
Publisher :
ISBN 13 :
Total Pages : 2156 pages
Book Rating : 4.:/5 (319 download)
Download or read book Index Medicus written by and published by . This book was released on 2001-08 with total page 2156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author : Gennady T. Sukhikh
Publisher : Springer
ISBN 13 : 3319750348
Total Pages : 334 pages
Book Rating : 4.3/5 (197 download)
Download or read book Multiparametric Ultrasound Diagnosis of Breast Diseases written by Gennady T. Sukhikh and published by Springer. This book was released on 2018-06-08 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This richly illustrated book provides a comprehensive overview of the use of current ultrasound techniques, including contrast-enhanced ultrasound and ultrasonic elastography, in the diagnosis of breast disease. The advantages and pitfalls of the various imaging modalities are identified, and it is explained how combined use of the modalities – multiparametric ultrasound – aids diagnosis and in particular assists in the differentiation of benign and malignant disease. Readers will find detailed description and illustration of the imaging appearances of age-related features (including in children and adolescents), the most important benign diseases, different forms of breast cancer, mammary gland pathology in the contexts of pregnancy and female reproductive system disease, chest gland pathology in males, and recurrent and metastatic disease. In addition, ultrasound-guided breast interventions and imaging of breast implants are discussed. Specialists in ultrasound diagnostics, radiologists, oncologists, and surgeons will all find this topical book to be both interesting and helpful in daily clinical practice.
Author : Giuliano Mariani
Publisher : Springer Science & Business Media
ISBN 13 : 8847027667
Total Pages : 306 pages
Book Rating : 4.8/5 (47 download)
Download or read book Atlas of Lymphoscintigraphy and Sentinel Node Mapping written by Giuliano Mariani and published by Springer Science & Business Media. This book was released on 2012-12-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although lymphoscintigraphy was originally introduced into clinical routine for identification of the cause of peripheral edema, more recently it has been widely applied for radioguided biopsy of the sentinel lymph node in patients with solid cancers. The procedure is now considered crucial for adequate planning of oncologic surgery in a growing number of cancers. This atlas presents a collection of richly illustrated teaching cases that demonstrate the clinical relevance and impact of lymphoscintigraphy in different pathologic conditions. After introductory chapters on the anatomy, physiology, and pathophysiology of lymphatic circulation, the role of lymphoscintigraphy in differential diagnosis of peripheral edema and characterization of intracavitary lymph effusions is addressed. The principal focus of the book, however, is on the use of lymphoscintigraphic mapping for radioguided sentinel node biopsy in cutaneous melanoma and cancers at a range of anatomic sites. The most commonly observed lymphoscintigraphic patterns are depicted, and anatomic variants and technical pitfalls of the procedure receive careful attention. The role of tomographic multimodality imaging is also considered. The atlas will be an excellent learning tool for residents in nuclear medicine and other specialists with an interest in the field.
Author : Urs Albrecht
Publisher : Springer Science & Business Media
ISBN 13 : 1441912622
Total Pages : 306 pages
Book Rating : 4.4/5 (419 download)
Download or read book The Circadian Clock written by Urs Albrecht and published by Springer Science & Business Media. This book was released on 2010-01-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.
Author :
Publisher :
ISBN 13 :
Total Pages : 610 pages
Book Rating : 4.M/5 ( download)
Download or read book Cerebrovascular Bibliography written by and published by . This book was released on 1965 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mahmut Gazi Yasargil
Publisher : Thieme
ISBN 13 : 3131735414
Total Pages : 428 pages
Book Rating : 4.1/5 (317 download)
Download or read book Microneurosurgery, Volume IV A written by Mahmut Gazi Yasargil and published by Thieme. This book was released on 2013-01-09 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume IVA examines in detail the fields of functional and morphologic neuroanatomy, neuropathology, and neurophysiology, providing a comprehensive basis for the evaluation of findings from advanced neuroimaging techniques. The author and his collaborators on this volume show how innovative concepts in the areas mentioned above can be used to redefine the operability of CNS tumors.
