Molecular Targets and Strategies in Cancer Prevention

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Author :
Publisher : Springer
ISBN 13 : 3319312545
Total Pages : 182 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Molecular Targets and Strategies in Cancer Prevention by : Malay Chatterjee

Download or read book Molecular Targets and Strategies in Cancer Prevention written by Malay Chatterjee and published by Springer. This book was released on 2016-06-16 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on the understanding of molecular pathways by which normal cell progress to the definable stage of cancer. The chapters explore microbiota and chronic inflammation, multiple myeloma chemoprevention, microRNAs, cancer regulation, liquid biopsies, and angiogenesis. Recent advances of molecular risk assessment, tumor microenvironment, microneoplasia, malignant gene expressions are highlighted to provide a means and design of future cancer prevention strategies and challenges thereupon. The volume also explores various receptor drugs that are in development process with the emphasis of inhibitors used to prevent malignant gene expression. The book bridges the gap between basic science and clinical application of current knowledge of cancer and emphasizes that tumor progression and cancer metastasis are not random - treatments and cure are logical and eventual. Expertly authored and drawing from a wealth of international perspectives, Molecular Targets and Strategies in Cancer Prevention is invaluable reading for clinicians and researchers in the fields of oncology and molecular biology.

Molecular Targets in Cancer Prevention

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Author :
Publisher :
ISBN 13 :
Total Pages : 197 pages
Book Rating : 4.:/5 (123 download)

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Book Synopsis Molecular Targets in Cancer Prevention by :

Download or read book Molecular Targets in Cancer Prevention written by and published by . This book was released on 2016 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Prevention

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Author :
Publisher : Humana
ISBN 13 : 9781493954469
Total Pages : 0 pages
Book Rating : 4.9/5 (544 download)

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Book Synopsis Cancer Prevention by : Ann M. Bode

Download or read book Cancer Prevention written by Ann M. Bode and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focused on the discovery of precise molecular targets for the development of the cancer preventive agents, Cancer Prevention: Dietary Factors and Pharmacology provides researchers and non-researchers with practical methodologies for developing and validating small molecule and phytochemical-derived drug discovery and mechanisms by which these compounds can modulate distinct target proteins involved in oncogenic signaling. While this volume is primarily focused toward cancer prevention research, the range of techniques demonstrated in the book also provides an introduction of cancer prevention research methods to researchers outside the field. Chapters deal with a critical discussion of both laboratory and clinical topics, with each chapter containing both a discursive section along with a detailed methods section. As part of the Methods in Pharmacology and Toxicology series, this meticulous volume includes the kind of key implementation advice that seeks to ensure successful results in the lab. Practical and authoritative, Cancer Prevention: Dietary Factors and Pharmacology aims to guide research toward identifying molecular targets and conducting human studies with phytochemicals which would, ideally, provide an enhanced approach to the goal of personalized cancer prevention.

Phytochemicals and Cancer - Possible Molecular Targets of Phytochemicals in Cancer Prevention and Therapy

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (115 download)

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Book Synopsis Phytochemicals and Cancer - Possible Molecular Targets of Phytochemicals in Cancer Prevention and Therapy by : Victor P. Bagla

Download or read book Phytochemicals and Cancer - Possible Molecular Targets of Phytochemicals in Cancer Prevention and Therapy written by Victor P. Bagla and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals and Cancer - Possible Molecular Targets of Phytochemicals in Cancer Prevention and Therapy.

Molecular Targets and Cancer Therapeutics (Part 1)

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9815080385
Total Pages : 390 pages
Book Rating : 4.8/5 (15 download)

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Book Synopsis Molecular Targets and Cancer Therapeutics (Part 1) by : Faris Q.B. Alenzi

Download or read book Molecular Targets and Cancer Therapeutics (Part 1) written by Faris Q.B. Alenzi and published by Bentham Science Publishers. This book was released on 2023-04-20 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every year around the world. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early-stage diagnosis. Molecular Targets and Cancer presents information about cancer diagnosis and therapy in a simple way. It covers several aspects of the topic with updated information on par with medical board levels. The book features contributions from experts and includes an overview of cancer from basic biology and pathology, classifications, surveillance, prevention, diagnosis, types of cancer, treatment and prognosis. The first part of this book introduces the reader to cancer epidemiology, genetic alterations in cancer, exogenous and endogenous factors in carcinogenesis, roles for growth factors in cancer progression, cell signaling in cancer, transcription factors in cancer, and cancer genetics and epigenetics. This comprehensive guide is a valuable resource for oncologists, researchers, and all medical professionals who work in cancer care and research.

Molecular Biology of The Cell

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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Prevention with Molecular Target Therapies

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Author :
Publisher : Mdpi AG
ISBN 13 : 9783036579276
Total Pages : 0 pages
Book Rating : 4.5/5 (792 download)

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Book Synopsis Cancer Prevention with Molecular Target Therapies by : Laura Paleari

Download or read book Cancer Prevention with Molecular Target Therapies written by Laura Paleari and published by Mdpi AG. This book was released on 2023-06-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized medicine plays an important role in cancer prevention. To date, it is clear that many cancers are molecularly distinct subtypes, and different therapeutic approaches would be required for each. Indeed, the identification of cancer susceptibility genes permits identifying patients "at risk" of developing neoplasia and supports modifying individual risk behaviors or the choice of preventive therapy. Additionally, the efficacy of various targeted therapies in different cancer subtypes suggests that treatment choices in the near future will be more and more centered on molecular signatures. Data from preclinical, clinical, and observational studies have revealed the ability to prevent cancer development for compounds with different indications than cancer. The concept of drug repurposing permits combinations that can target several critical pathways of a specific disease, decreasing the risk of resistance observed when using single-agent targeted therapy. This open-access Special Issue brings together original research and review articles on molecular oncology with attention to the early detection and prevention of cancer. It highlights new findings, methods, and technical advances in molecular cancer research. The main feature of this Special Issue is to provide an open-source sharing of significant works in the field of molecular oncology that can increase our understanding of cancer development, which may lead to the discovery of new molecular diagnostic technologies and targeted therapeutics.

Molecular Targets and Cancer Therapeutics (Part 2)

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9815124609
Total Pages : 363 pages
Book Rating : 4.8/5 (151 download)

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Book Synopsis Molecular Targets and Cancer Therapeutics (Part 2) by : Faris Q.B. Alenzi

Download or read book Molecular Targets and Cancer Therapeutics (Part 2) written by Faris Q.B. Alenzi and published by Bentham Science Publishers. This book was released on 2023-04-20 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every year around the world. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early-stage diagnosis. Molecular Targets and Cancer presents information about cancer diagnosis and therapy in a simple way. It covers several aspects of the topic with updated information on par with medical board levels. The book features contributions from experts and includes an overview of cancer from basic biology and pathology, classifications, surveillance, prevention, diagnosis, types of cancer, treatment and prognosis. The second part of this book discusses specialized topics in clinical oncology which include the pathophysiology of various types of cancer, cancer screening, different types of cancer surgery, cancer stem cell-targeted immunotherapy, nanotechnology for precision medicine applications in cancer and cancer surveillance. This comprehensive guide is a valuable resource for oncologists, researchers, and all medical professionals who work in cancer care and research.

Cancer Prevention with Molecular Target Therapies 3.0

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Author :
Publisher : Mdpi AG
ISBN 13 : 9783036579092
Total Pages : 0 pages
Book Rating : 4.5/5 (79 download)

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Book Synopsis Cancer Prevention with Molecular Target Therapies 3.0 by : Laura Paleari

Download or read book Cancer Prevention with Molecular Target Therapies 3.0 written by Laura Paleari and published by Mdpi AG. This book was released on 2023-06-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized medicine is playing an important role in cancer prevention. To date, it is clear that many cancers are molecularly distinct subtypes, and different therapeutic approaches would be required for each. This Special Issue brings together original research and review articles on molecular oncology with attention to the early detection and prevention of cancer. It highlights new findings, methods, and technical advances in molecular cancer research. The main feature of this reprint was to provide an open-source sharing of significant works in the field of molecular oncology that can increase our understanding of cancer development. Topics include: Molecular methods to personalize cancer screening and detection; Molecular target therapies to prevent cancer development and metastases; Identification and new aspects of cellular signaling molecules and pathways for target discovery, drug design and personalized and gender medicine; Drug repurposing for cancer prevention; Molecular modeling studies.

Cox-2

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 380557536X
Total Pages : 300 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Cox-2 by : Joseph R. Bertino

Download or read book Cox-2 written by Joseph R. Bertino and published by Karger Medical and Scientific Publishers. This book was released on 2003-01-01 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous investigators have found increased levels of cyclooxygenase-2 (COX-2) in both premalignant and malignant tissues. Moreover, animals engineered to be COX-2 deficient or treated with a selective COX-2 inhibitor showed reduced tumor formation and growth. The present book reviews these findings suggesting that COX-2 is a valid molecular target for the prevention and treatment of cancer. The first chapters are devoted to the epidemiology of nonsteroidal anti-inflammatory drugs (NSAIDs) and cancer, the pharmacology of COX-2 inhibitors and the regulation of COX-2 expression in human cancers. Besides, the book contains a series of chapters examining the link between COX-2 and cancer in specific organs (e.g. skin, breast, cervix, digestive tract, lung, etc.). Furthermore, several clinical trials assessing the potential of COX-2 inhibitors for preventing and treating cancer are described. The final chapter provides an up-to-date consideration of COX-independent targets of NSAIDs and related compounds in cancer prevention and treatment. This state-of-the-art publication is recommended reading not only for medical and radiation oncologists, but also for pharmacologists, gastroenterologists and other subspecialists.

Cellular and Molecular Targets for Chemoprevention

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Publisher : CRC Press
ISBN 13 : 9780849345302
Total Pages : 400 pages
Book Rating : 4.3/5 (453 download)

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Book Synopsis Cellular and Molecular Targets for Chemoprevention by : Vernon E. Steele

Download or read book Cellular and Molecular Targets for Chemoprevention written by Vernon E. Steele and published by CRC Press. This book was released on 1992-04-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Targets for Chemoprevention provides comprehensive coverage of target mechanisms that have proved valuable in chemoprevention research, in addition to mechanisms that may prove valuable in the near future. The book discusses such topics as growth factor receptor modulation, cell-to-cell communication, differentiation modulation, antisense olgonucleotides, tumor suppressor genes, free radical scavengers, and polyamine synthesis inhibition. Cellular and Molecular Targets for Chemoprevention will be welcomed by scientists in all areas of cancer/chemoprevention research, pharmaceutical researchers, and advanced students.

Perspectives in Cancer Prevention-Translational Cancer Research

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Publisher : Springer Science & Business Media
ISBN 13 : 8132215338
Total Pages : 173 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Perspectives in Cancer Prevention-Translational Cancer Research by : Perumana R. Sudhakaran

Download or read book Perspectives in Cancer Prevention-Translational Cancer Research written by Perumana R. Sudhakaran and published by Springer Science & Business Media. This book was released on 2013-10-25 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory or population studies into clinical application to reduce incidence of cancer , morbidity and mortality. It is becoming increasingly evident that cancer is a preventable disease. The IVth International Symposium on Translational Cancer Research held in Udaipur, India in December 2011, discussed various aspects of the biological processes in cancer cells and approaches to cancer prevention. A few contributions from this meeting are presented in this book, providing an in depth analysis of data on cancer prevention and therapeutics. These contributions are either critical reviews or research reports. The topics discussed include evidence-based nutritional recommendations for cancer patients and survivors, risk factors such as stress, enrichment of tumour stem cells by anticancer drug treatment contributing to tumour recurrence and the mechanism of anticancer effects of various natural products. Chemosensitizing effect of curcumin, anti-cancer effect of products from neem, action of sulforaphane and cytotoxic effect of a number of novel synthetic coordination complexes of trace metals have been discussed. Novel molecular targets of angiogenesis and molecular basis of the gender bias to thyroid cancer have also been discussed . This book provides useful information on translational cancer research to clinicians and biomedical scientists.

Natural Products for Cancer Chemoprevention

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Publisher : Springer Nature
ISBN 13 : 3030398552
Total Pages : 639 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Natural Products for Cancer Chemoprevention by : John M. Pezzuto

Download or read book Natural Products for Cancer Chemoprevention written by John M. Pezzuto and published by Springer Nature. This book was released on 2020-04-03 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the efficacy of various naturally occurring chemopreventive agents in preventing or delaying cancer. It focuses on the holistic chemopreventive concept, demonstrating the relevant response is the combined effect of a series of compounds that alone have been shown to have some effect in different experimental models. Written by leading experts in the field, the contributions provide details of research on various chemopreventive agents. Offering insights into the unique molecular targets and mechanisms, safety issues, molecular efficacy, and occurrence in nature of these compounds, the book is a valuable resource for all scientists working in biomedicine, and specifically in cancer research.

Prevention of Cancer

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Publisher : Nova Publishers
ISBN 13 : 9781604562293
Total Pages : 234 pages
Book Rating : 4.5/5 (622 download)

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Book Synopsis Prevention of Cancer by : Joel W. Rosenthal

Download or read book Prevention of Cancer written by Joel W. Rosenthal and published by Nova Publishers. This book was released on 2008 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest research on advances in genetics, molecular medicine, biotechnologies, and behavioural sciences that have an impact on primary, secondary and tertiary cancer prevention including: (a) Basic mechanisms of neoplastic diseases leading to the identification of molecular pathways that can be employed as targets for cancer prevention; (b) Descriptive, analytical, and molecular epidemiology with emphasis on developing biomarkers of cancer risk assessment and response to cancer prevention; (c) Laboratory and clinical procedures for prognostic evaluation of malignant tumour transformation, progression and response to treatment with cancer preventive agents; (d) Discoveries of natural substances and synthetic agents that have promising cancer preventive potential and elucidating their mechanistic action; (e) Development and assessment of cancer preventive approaches that have potential for being translated into the clinic; (f) Cancer prevention pre-clinical studies and clinical trials; (g) Patient management and education, management of curable lesions, education and lifestyle modification and the role of behavioural factors in cancer etiology and prevention.

Nutraceuticals and Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 9400726309
Total Pages : 383 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Nutraceuticals and Cancer by : Fazlul H. Sarkar

Download or read book Nutraceuticals and Cancer written by Fazlul H. Sarkar and published by Springer Science & Business Media. This book was released on 2011-11-22 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about Nutraceuticals in cancer therapy, specifically targeted and Adjuvant therapy. It shows several approaches for possibly reducing systemic toxicity. This book illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in the prevention and/or treatment of human malignancies known to be mediated through alterations in multiple molecular targets. This book contains sixteen chapters which begin with historical perspective on the value of natural agents in the prevention of human malignancies followed by a series of current topics on multiple nutraceuticals targeting multiple cancers. This collection would likely be useful for bringing newer generations with broader perspectives in launching cutting-edge innovative molecular research, which would certainly help in designing targeted clinical trials in order to realize the dream of customize strategies for the prevention and/or treatment of human malignancies without causing any systemic toxicity. Moreover, the knowledge gained would allow novel utilization of nutraceuticals as adjunct to both conventional chemotherapy and radiation therapy in order to improve the overall quality of life and survival of patients diagnosed with cancers.

Phytochemicals

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535121707
Total Pages : 351 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Phytochemicals by : Venketeshwer Rao

Download or read book Phytochemicals written by Venketeshwer Rao and published by BoD – Books on Demand. This book was released on 2015-09-30 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global dietary recommendations emphasize the consumption of plant-based foods for the prevention and management of chronic diseases. Plants contain many biologically active compounds referred to as phytochemicals or functional ingredients. These compounds play an important role in human health. Prior to establishing the safety and health benefits of these compounds, they must first be isolated, purified, and their physico-chemical properties established. Once identified, their mechanisms of actions are studied. The chapters are arranged in the order from isolation, purification and identification to in vivo and clinical studies, there by covering not only the analytical procedures used but also their nutraceutical and therapeutic properties.

Molecular Targets for Cancer Therapy and Prevention

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Author :
Publisher :
ISBN 13 :
Total Pages : 170 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Molecular Targets for Cancer Therapy and Prevention by : Gary E. Gallick

Download or read book Molecular Targets for Cancer Therapy and Prevention written by Gary E. Gallick and published by . This book was released on 1998* with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: