Molecular Mechanisms Of The Aging Process And Rejuvenation

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Molecular Mechanisms of the Aging Process and Rejuvenation

Author : Naofumi Shiomi
Publisher : BoD – Books on Demand
ISBN 13 : 9535125680
Total Pages : 128 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Molecular Mechanisms of the Aging Process and Rejuvenation by : Naofumi Shiomi

Download or read book Molecular Mechanisms of the Aging Process and Rejuvenation written by Naofumi Shiomi and published by BoD – Books on Demand. This book was released on 2016-08-31 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous studies had been performed to elucidate the mechanisms of aging and to achieve rejuvenation, with some success reported in recent years. However, at present, the findings from those studies are not sufficient to resolve the issue of aging. This book presents an overview of recent topics on cellular aging and rejuvenation. In the early chapters, the molecular mechanisms of aging via the activities of clock and ion channel proteins, in addition to overall aspects, are discussed. In the latter part, the aging of the skin, immune system, and brain is discussed. This book will prove useful for those studying or developing new drugs to counter the aging process and will encourage the development of novel ideas for rejuvenation.

Molecular Mechanisms of Aging

Author : Konrad Beyreuther
Publisher : Springer Science & Business Media
ISBN 13 : 3642842240
Total Pages : 327 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Molecular Mechanisms of Aging by : Konrad Beyreuther

Download or read book Molecular Mechanisms of Aging written by Konrad Beyreuther and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Skin Aging

Author : Barbara A. Gilchrest
Publisher : Springer Science & Business Media
ISBN 13 : 3540329536
Total Pages : 205 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Skin Aging by : Barbara A. Gilchrest

Download or read book Skin Aging written by Barbara A. Gilchrest and published by Springer Science & Business Media. This book was released on 2006-04-20 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The topic of skin aging is of growing importance to all working in the field of dermatology, aesthetic medicine and cosmetic medicine. Two internationally well-known and leading experts in the field present a comprehensive state-of-the-art review on all aspects of skin aging. With its clear, concise and reader-friendly format this book has all the potential to become the Bible of skin aging. Every specialist interested in dermatology, aesthetic medicine, cosmetic science, cutaneous biology and aging research will find indispensable information of great value for his or her daily work.

Ending Aging

Author : Aubrey de Grey
Publisher : Macmillan + ORM
ISBN 13 : 1429931833
Total Pages : 452 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Ending Aging by : Aubrey de Grey

Download or read book Ending Aging written by Aubrey de Grey and published by Macmillan + ORM. This book was released on 2007-09-04 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

Handbook on Immunosenescence

Author : Tamas Fulop
Publisher : Springer Science & Business Media
ISBN 13 : 1402090633
Total Pages : 1693 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook on Immunosenescence by : Tamas Fulop

Download or read book Handbook on Immunosenescence written by Tamas Fulop and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 1693 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.

Epigenetics of Aging

Author : Trygve O. Tollefsbol
Publisher : Springer Science & Business Media
ISBN 13 : 1441906398
Total Pages : 462 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Epigenetics of Aging by : Trygve O. Tollefsbol

Download or read book Epigenetics of Aging written by Trygve O. Tollefsbol and published by Springer Science & Business Media. This book was released on 2009-11-11 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Textbook of Aging Skin

Author : Miranda A. Farage
Publisher : Springer Science & Business Media
ISBN 13 : 3540896554
Total Pages : 1255 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Textbook of Aging Skin by : Miranda A. Farage

Download or read book Textbook of Aging Skin written by Miranda A. Farage and published by Springer Science & Business Media. This book was released on 2009-12-02 with total page 1255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive ‘Major Reference Book’ compiles all current and latest information on aging skin in a two-volume set. Highly structured with a reader-friendly format, it covers a wide range of areas such as basic sciences, the different diseases and conditions which occur with aging (from malignant to non-malignant), the latest techniques and methods being used such as bioengineering methods and biometrics as well as toxicological and safety considerations for the elderly population. It also illustrates the global consumers’ sociological and psychological implications, ethnicity and gender differences and includes marketing considerations for this elderly group. This unique and comprehensive guide will become the main reference textbook on this topic.

Aging and Age-Related Disorders

Author : Stephen Bondy
Publisher : Springer Science & Business Media
ISBN 13 : 1607616025
Total Pages : 468 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Aging and Age-Related Disorders by : Stephen Bondy

Download or read book Aging and Age-Related Disorders written by Stephen Bondy and published by Springer Science & Business Media. This book was released on 2010-09-02 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features that characterize the aging process include the gradual accumulation of cell damage after prolonged exposure to oxidative and inflammatory events over a lifetime. In addition to the accretion of lesions, the intrinsic levels of pro-oxidant and aberrant immune responses are elevated with age. These adverse events are often further enhanced by the chronic and slow progressing diseases that characterize the senescent brain and cardiovascular system. The incidence of some disorders such as Alzheimer's disease and vascular diseases are sufficiently prevalent in the extreme elderly that these disorders can arguably be considered "normal". Aging and Aging-Related Disorders examines the interface between normal and pathological aging, and illustrates how this border can sometimes be diffuse. It explores and illustrates the processes underlying the means by which aging becomes increasingly associated with inappropriate levels of free radical activity and how this can serve as a platform for the progression of age-related diseases. The book provides chapters that examine the interactive relationship between systems in the body that can enhance or sometimes even limit cellular longevity. In addition, specific redox mechanisms in cells are discussed. Another important aspect for aging discussed here is the close relationship between the systems of the body and exposure to environmental influences of oxidative stress that can affect both cellular senescence and a cell’s nuclear DNA. What may be even more interesting to note is that these external stressors are not simply confined to illnesses usually associated with aging, but can be evident in maturing and young individuals. A broad range of internationally recognized experts have contributed to this book. Their aim is to successfully highlight emerging knowledge and therapy for the understanding of the basis and development of aging–related disorders.

Mechanisms and Management of Senescence

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 183969050X
Total Pages : 132 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Mechanisms and Management of Senescence by :

Download or read book Mechanisms and Management of Senescence written by and published by BoD – Books on Demand. This book was released on 2022-09-14 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Senescence represents a complex universal phenomenon that can be impacted by several factors. It is emerging as a therapeutic target for several diseases. This book presents an overview of the current mechanisms and management of senescence in humans. It also provides comparative data on senescence in animals and plants.

The Evolution of Senescence in the Tree of Life

Author : Richard P. Shefferson
Publisher : Cambridge University Press
ISBN 13 : 1108138608
Total Pages : 445 pages
Book Rating : 4.1/5 (81 download)

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Book Synopsis The Evolution of Senescence in the Tree of Life by : Richard P. Shefferson

Download or read book The Evolution of Senescence in the Tree of Life written by Richard P. Shefferson and published by Cambridge University Press. This book was released on 2017-02-23 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The existing theories on the evolution of senescence assume that senescence is inevitable in all organisms. However, recent studies have shown that this is not necessarily true. A better understanding of senescence and its underlying mechanisms could have far-reaching consequences for conservation and eco-evolutionary research. This book is the first to offer interdisciplinary perspectives on the evolution of senescence in many species, setting the stage for further developments. It brings together new insights from a wide range of scientific fields and cutting-edge research done on a multitude of different animals (including humans), plants and microbes, giving the reader a complete overview of recent developments and of the controversies currently surrounding the topic. Written by specialists from a variety of disciplines, this book is a valuable source of information for students and researchers interested in ageing and life history traits and populations.

Cosmetic Dermatology

Author : Zoe Diana Draelos
Publisher : John Wiley & Sons
ISBN 13 : 111865546X
Total Pages : 34 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Cosmetic Dermatology by : Zoe Diana Draelos

Download or read book Cosmetic Dermatology written by Zoe Diana Draelos and published by John Wiley & Sons. This book was released on 2015-10-14 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: Back for a new edition, Zoe Draelos' outstanding resource to cosmetic dermatology again provides a highly-illustrated, clinical guide to the full range of cosmetic skin treatments. Bringing together experts from research, industry, surgery and practice, it is structured in four distinct parts for easy navigation by the busy clinician: Basic Concepts - giving an overview of the physiology pertinent to cosmetic dermatology and the delivery systems by which treatments can take effect; Hygiene Products - evaluating cleansing and moisturising products; Adornment - looking at aesthetic techniques such as cosmetics, nail protheses and hair treatment; Antiaging - ie, injectables, resurfacing and skin contouring techniques, and the rapidly growing area of Cosmeceuticals. With over 300 high-quality images and key summary boxes throughout, this new edition incorporates the newest procedural innovations in this rapidly developing field. Perfect for all dermatologists, especially those specialising in cosmetic dermatology and whether hospital-based or in private practice, it provides the complete cosmetic regimen for your patients and will be an indispensable tool to consult over and over again.

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

Author : Bharat B. Aggarwal
Publisher : Springer Science & Business Media
ISBN 13 : 0387464018
Total Pages : 502 pages
Book Rating : 4.3/5 (874 download)

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Book Synopsis The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease by : Bharat B. Aggarwal

Download or read book The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease written by Bharat B. Aggarwal and published by Springer Science & Business Media. This book was released on 2007-08-06 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.

Muscle Atrophy

Author : Junjie Xiao
Publisher : Springer
ISBN 13 : 9811314357
Total Pages : 618 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Muscle Atrophy by : Junjie Xiao

Download or read book Muscle Atrophy written by Junjie Xiao and published by Springer. This book was released on 2018-11-02 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book’s fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology.

Current Topics on Superfoods

Author : Naofumi Shiomi
Publisher : BoD – Books on Demand
ISBN 13 : 1789232082
Total Pages : 92 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Current Topics on Superfoods by : Naofumi Shiomi

Download or read book Current Topics on Superfoods written by Naofumi Shiomi and published by BoD – Books on Demand. This book was released on 2018-05-30 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Superfood is a food that contains active ingredients or important nutrients at extremely high levels. Protective effects of superfoods on diseases have been remarked. Recently, several foods such as camu camu, chia seeds and goji berries are well known, and their trade has been rapidly increasing in the past 10 years. The purpose of this book is the development of a novel concept of superfoods and diet-containing superfoods. In the chapters, researchers have introduced the active components of superfoods and diets using such foods. Superfoods derived from fish and by-products of beer brewing are also introduced. Moreover, the procedure of bio-accessibility is also considered. I expect that the readers understand this novel concept of superfoods.

Stem Cell Aging: Mechanisms, Consequences, Rejuvenation

Author : Hartmut Geiger
Publisher : Springer
ISBN 13 : 370911232X
Total Pages : 357 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Stem Cell Aging: Mechanisms, Consequences, Rejuvenation by : Hartmut Geiger

Download or read book Stem Cell Aging: Mechanisms, Consequences, Rejuvenation written by Hartmut Geiger and published by Springer. This book was released on 2015-07-06 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like the skin, blood and intestines. Understanding the molecular and cellular mechanisms involved is critical for developing approaches to attenuate stem cell aging and could pave the way for improved quality of life among the elderly. Written by highly prominent experts in the field, this book presents the current state of knowledge on these mechanisms. It offers insights into stem cell function, explains in detail the mechanisms of stem cell aging in model organisms as well as mammalian systems and describes related diseases and approaches to attenuating stem cell aging or achieving rejuvenation. The book is intended for all scientists and clinicians working with stem cells, aging mechanisms or age-related diseases.

Molecular Biology of Aging

Author : Leonard Guarente
Publisher : CSHL Press
ISBN 13 : 0879698241
Total Pages : 610 pages
Book Rating : 4.8/5 (796 download)

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Book Synopsis Molecular Biology of Aging by : Leonard Guarente

Download or read book Molecular Biology of Aging written by Leonard Guarente and published by CSHL Press. This book was released on 2008 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the major threads in the molecular genetics of aging, including genes that regulate aging, causes of aging, evolutionary theories of aging, and the relationship between diet and aging. Among specific topics covered are calorie restriction, mitochondria, sirtuins, telomeres, stem cells, and cancer.

Molecular Mechanisms of Skin Aging and Age-Related Diseases

Author : Taihao Quan
Publisher : CRC Press
ISBN 13 : 1498704654
Total Pages : 263 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Molecular Mechanisms of Skin Aging and Age-Related Diseases by : Taihao Quan

Download or read book Molecular Mechanisms of Skin Aging and Age-Related Diseases written by Taihao Quan and published by CRC Press. This book was released on 2016-04-21 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our skin changes as we age. It becomes thinner and loses fat, making it less plump and smooth. Clinically, aged skin is characterized by wrinkles, sagging, age spots and dryness. Emphasizing laboratory and clinical research, this book comprehensively describes the molecular mechanisms of human skin-aging and age-related skin diseases. This includes