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Author : Jane Ann Gross
Publisher :
ISBN 13 :
Total Pages : 272 pages
Book Rating : 4.:/5 (33 download)
Download or read book Molecular Cloning and Characterization of the Murine T Cell Activation Antigen written by Jane Ann Gross and published by . This book was released on 1990 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jonathan Soboloff
Publisher : CRC Press
ISBN 13 : 149870509X
Total Pages : 258 pages
Book Rating : 4.4/5 (987 download)
Download or read book Signaling Mechanisms Regulating T Cell Diversity and Function written by Jonathan Soboloff and published by CRC Press. This book was released on 2017-03-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
Author :
Publisher :
ISBN 13 :
Total Pages : 1364 pages
Book Rating : 4.:/5 (319 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1994 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Russell F. Doolittle
Publisher : University Science Books
ISBN 13 : 9780935702545
Total Pages : 118 pages
Book Rating : 4.7/5 (25 download)
Download or read book Of Urfs And Orfs written by Russell F. Doolittle and published by University Science Books. This book was released on 1986 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: In these days of facile cloning and rapid DNA sequencing, it is not uncommon for investigators to find themselves with a DNA sequence that may or may not code for a known gene product. The sequence is 'open' when read in an appropriate frame, which is to say that there is a long run of amino acid codons before the appearance of a terminator codon. How can we find out if this 'unidentified reading frame' (URF) really codes for a genuine protein, and how can we identify it if it exists? There are two general strategies, both of which can also be applied to the characterization of any 'open reading frame' (ORF), whether or not it has been 'identified'. The first and simplest approach involves computer searching and analysis; the second employs antibodies raised against synthetic peptides patterned on the sequence of the expected gene product. Both methods have been used with great success by many investigators. Each has, nonetheless, its pitfalls and frustrations. This primer is meant to guide the researcher past those obstacles as much as possible. Graduate students and researchers interested in amino acid sequencing; molecular biologists, biochemists, chemists, and biotechnologists.
Author : Miyuki Azuma
Publisher : Springer Nature
ISBN 13 : 9813297174
Total Pages : 326 pages
Book Rating : 4.8/5 (132 download)
Download or read book Co-signal Molecules in T Cell Activation written by Miyuki Azuma and published by Springer Nature. This book was released on 2019-11-22 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of T cells. Following an initial overview, subsequent chapters examine each co-signal molecule in turn and discuss the mechanisms by which co-signal molecules regulate the different types of T cell. The second part covers various clinical applications, including in autoimmune disease, neurological disorders, transplantation, graft-versus-host disease, and cancer immunotherapy. To date, co-stimulation blockade and co-inhibition blockade have shown beneficial effects and many additional clinical trials targeting co-signal molecules are ongoing. The mechanisms underlying these successful treatments are explained and the future therapeutic potential in the aforementioned diseases is evaluated. Co-signal Molecules in T Cell Activation will be a valuable reference guide to co-stimulation for basic and clinical researchers in the fields of both immunology and pharmaceutical science.
Author :
Publisher :
ISBN 13 :
Total Pages : 1104 pages
Book Rating : 4.3/5 (91 download)
Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1991 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)
Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David B. Mount
Publisher : Elsevier Health Sciences
ISBN 13 : 1416002529
Total Pages : 604 pages
Book Rating : 4.4/5 (16 download)
Download or read book Molecular and Genetic Basis of Renal Disease written by David B. Mount and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: This companion to Brenner and Rector's The Kidney offers a state-of-the-art summary of the most recent advances in renal genetics. Molecular and Genetic Basis for Renal Disease provides the nephrologist with a comprehensive look at modern investigative tools in nephrology research today, and reviews the molecular pathophysiology of the nephron as well as the most common genetic and acquired renal diseases. A comprehensive clinical review of Medelian renal disease is also be included. Detailed review of the molecular anatomy and pathophysiology of the nephron that provides relevant basic science to consider when diagnosing and managing patients with these disorders.
Author : Ronald Hoffman
Publisher : Elsevier Health Sciences
ISBN 13 : 1437729282
Total Pages : 2789 pages
Book Rating : 4.4/5 (377 download)
Download or read book Hematology written by Ronald Hoffman and published by Elsevier Health Sciences. This book was released on 2013-01-01 with total page 2789 pages. Available in PDF, EPUB and Kindle. Book excerpt: This leading text reflects both the new direction and explosive growth of the field of hematology. Edited and written by practitioners who are the leaders in the field, the book covers basic scientific foundations of hematology while focusing on its clinical aspects. This edition has been thoroughly updated and includes ten new chapters on cellular biology, haploidentical transplantation, hematologic manifestations of parasitic diseases, and more. The table of contents itself has been thoroughly revised to reflect the rapidly changing nature of the molecular and cellular areas of the specialty. Over 1,000 vivid images, now all presented in full color for the first time, include a collection of detailed photomicrographs in every chapter, selected by a hematopathology image consultant. What's more, this Expert Consult Premium Edition includes access to the complete contents of the book online, fully searchable and updated quarterly by Dr. Hoffman himself. - Publisher.
Author : An Rykx
Publisher :
ISBN 13 : 9789058676061
Total Pages : 0 pages
Book Rating : 4.6/5 (76 download)
Download or read book Protein Kinase D Downstream Effectors written by An Rykx and published by . This book was released on 2007-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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ISBN 13 :
Total Pages : 288 pages
Book Rating : 4.0/5 ( download)
Download or read book Abridged Index Medicus written by and published by . This book was released on 1997 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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ISBN 13 :
Total Pages : 580 pages
Book Rating : 4.:/5 (319 download)
Download or read book Research Grants written by and published by . This book was released on 1987 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Leslie E. Silberstein
Publisher : Elsevier Health Sciences
ISBN 13 : 1455740411
Total Pages : 2789 pages
Book Rating : 4.4/5 (557 download)
Download or read book Hematology E-Book written by Leslie E. Silberstein and published by Elsevier Health Sciences. This book was released on 2012-11-05 with total page 2789 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hematology, 6th Edition encompasses all of the latest scientific knowledge and clinical solutions in the field, equipping you with the expert answers you need to offer your patients the best possible outcomes. Ronald Hoffman, MD, Edward J. Benz, Jr., MD, Leslie E. Silberstein, MD, Helen Heslop, MD, Jeffrey Weitz, MD, John Anastasi, MD, and a host of world-class contributors present the expert, evidence-based guidance you need to make optimal use of the newest diagnostic and therapeutic options. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Make confident, effective clinical decisions by consulting the world's most trusted hematology reference. Access the complete contents online at www.expertconsult.com, with a downloadable image collection, regular updates, case studies, patient information sheets, and more. Apply all the latest knowledge on regulation of gene expression, transcription splicing, and RNA metabolism; pediatric transfusion therapy; principles of cell-based gene therapy; allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndrome in adults; hematology in aging; and much more, thanks to 27 brand-new chapters plus sweeping updates throughout. Find the information you need quickly and easily thanks to a completely reworked organization that better reflects today’s clinical practice. Visualize clinical problems more clearly with new and updated images that reflect the pivotal role of hematopathology in modern practice. Benefit from the experience and fresh perspective of new editor Dr. Jeffrey Weitz, Professor of Medicine at McMaster University School of Medicine and Executive Director of the Thrombosis and Atherosclerosis Research Institute in Ontario.
Author : Tasuku Honjo
Publisher : Academic Press
ISBN 13 : 9780123979339
Total Pages : 0 pages
Book Rating : 4.9/5 (793 download)
Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Academic Press. This book was released on 2014-12-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.
Author : Bo Dupont
Publisher : Springer
ISBN 13 : 3662399466
Total Pages : 636 pages
Book Rating : 4.6/5 (623 download)
Download or read book Immunobiology of HLA written by Bo Dupont and published by Springer. This book was released on 2013-12-20 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: This set reports the results of the 10th International Histocompatibility Workshop, in which 362 laboratories collaborated over a three year period in research projects on the classification of HLA genes and their products. Volume 1 describes the experimental design of the workshop studies and their results. Volume 2 is a collection of papers on the latest developments in the molecular biology of HLA systems. Immunobiology of HLA is a valuable reference for tissue typing laboratories, blood banks, and general research programs on HLA and related diseases because it identifies common sources of HLA genes and gene products to be used as reference reagents, and because it is the only complete compilation of the latest research and results in the field.
Author : Pramod M. Lad
Publisher : CRC Press
ISBN 13 : 9780849366949
Total Pages : 400 pages
Book Rating : 4.3/5 (669 download)
Download or read book Signal Transduction in Leukocytes written by Pramod M. Lad and published by CRC Press. This book was released on 1995-11-27 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal Transduction in Leukocytes presents important principles and various aspects of cellular regulation in leukocytes. The book discusses receptor structure and signaling, emphasizing cytokine receptors and the T cell and B cell antigen receptors. It investigates the role of the heterotrimeric G proteins and small G proteins as transducers. Authorities in each field cover a wide range of topics. They explore propagation of signaling cascades through second messengers and serine/threonine kinases, the initiation of signaling from the B and T cell antigen receptors by tyrosine phosphorylation and protein recruitment, and the role of signaling in cell-cell interactions and the regulation of the cell cycle. The book outlines the relationship of receptor signaling to inflammatory reactions of neutrophils, eosinophils, and macrophages.
Author : Chi-Kuang Huang
Publisher : CRC Press
ISBN 13 : 9780849363535
Total Pages : 322 pages
Book Rating : 4.3/5 (635 download)
Download or read book Protein Kinases in Blood Cell Function written by Chi-Kuang Huang and published by CRC Press. This book was released on 1993-02-22 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Kinases in Blood Cell Function provides an up-to-date, comprehensive review of protein kinases in various types of blood cell function. Blood cells discussed include T lymphocytes, B lymphocytes, platelets, mast cells, neutrophils, and macrophages. The book will interest pathologists, physiologists, oncologists, hematologists, leukocyte biologists, and immunologists. It will also benefit anyone interested in signal transduction and blood cell functions such as host defense, hemostasis, and immune response.
