Molecular Cardiology

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Principles of Molecular Cardiology

Author : Marschall S. Runge
Publisher : Springer Science & Business Media
ISBN 13 : 1592598781
Total Pages : 604 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Principles of Molecular Cardiology by : Marschall S. Runge

Download or read book Principles of Molecular Cardiology written by Marschall S. Runge and published by Springer Science & Business Media. This book was released on 2007-11-14 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: An easy-to-read survey of all the latest developments in molecular cardiologic research and therapy. The authors explain in a readable style the complex process of the heart's development, the molecular basis of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system.

Molecular Cardiology for the Cardiologists

Author : Bernard Swynghedauw
Publisher : Springer Science & Business Media
ISBN 13 : 1461520193
Total Pages : 266 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Molecular Cardiology for the Cardiologists by : Bernard Swynghedauw

Download or read book Molecular Cardiology for the Cardiologists written by Bernard Swynghedauw and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Cardiology for the Cardiologist provides a short, easily readable summary of what the new biology brings to cardiology. With this in mind, special efforts have been made to present many comprehensive schemes and drawings, as well as teaching tables. The five parts of the book provide a general introduction to the new language of biology; the normal structure of the heart and blood vessels; the physiopathology and the new therapeutic avenues that have been opened up by the new biology. A concise summary of the keys that assist the cardiologist or student who seeks to learn and read more about this field. Provides practical examples to illustrate the clinical interest of the new approach.

Molecular Cardiology

Author : Zhongjie Sun
Publisher : Springer Science & Business Media
ISBN 13 : 159259879X
Total Pages : 410 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Molecular Cardiology by : Zhongjie Sun

Download or read book Molecular Cardiology written by Zhongjie Sun and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of Molecular Cardiology: Methods and Protocols is to document state-of-the-art molecular and genetic techniques in the area of cardiology. These modern approaches enable researchers to readily study heart diseases at the molecular level and will promote the development of new therapeutic str- egies. Methods for genetic dissection, signal transduction, and microarray analysis are excellent tools for the study of the molecular mechanisms of cardiovascular diseases. Protocols for transgenesis take advantage of recent advances in many areas of molecular and cell biology. Transgenic models of heart diseases (cardiac hypertrophy, cardiac dysfunction, and so on. ) are powerful tools for the study of heart disease pathogenesis. Methods for gene transfer to heart tissue using viral and nonviral vectors form the basis of gene therapy for heart diseases. Heart-specific promoters containing a hypox- inducible cardioprotective gene switch are key for protection of the heart from ischemia. Gene and stem cell therapies open novel and exciting avenues for the prevention and treatment of heart diseases. Molecular Cardiology: Methods and Protocols consists of 26 chapters de- ing with various aspects of molecular cardiology, including gene transfer and gene therapy for cardiovascular disease, stem cell therapy for cardiovascular disease, gene analysis in the injured and hypertrophied heart, and transgenesis in cardiovascular research. This book provides step-by-step methods for the successful completion of experimental procedures, and would be useful for both experienced and new investigators in the field of molecular cardiology.

Molecular Cardiology for the Cardiologist

Author : Bernard Swynghedauw
Publisher : Springer Science & Business Media
ISBN 13 : 1461549698
Total Pages : 191 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Molecular Cardiology for the Cardiologist by : Bernard Swynghedauw

Download or read book Molecular Cardiology for the Cardiologist written by Bernard Swynghedauw and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Cardiology for the Cardiologist, Second Edition provides a short, easily readable summary of what the new biology brings to cardiology. Special efforts have been made to include comprehensive diagrams and drawings, as well as teaching tables, and also to keep the size of the second edition within the modest limits of the first edition. The book remains divided into 5 parts. The first part is a general introduction to the new terminology. The second part is devoted to the normal structure of the heart and vessels. Parts 3 and 4 deal with physiopathology. One of the important contributions of molecular biology to cardiology is a better understanding of the general process of adaptation of the heart and vessels to a permanent mechanical overloading. Such a process is generally called remodeling, and results from coordinate changes in the expression of the genes. The last part of the book includes information on gene and cellular therapy.

Molecular Cardiology in Clinical Practice

Author : Michael R. Sanders
Publisher : Springer Science & Business Media
ISBN 13 : 0585381410
Total Pages : 234 pages
Book Rating : 4.5/5 (853 download)

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Book Synopsis Molecular Cardiology in Clinical Practice by : Michael R. Sanders

Download or read book Molecular Cardiology in Clinical Practice written by Michael R. Sanders and published by Springer Science & Business Media. This book was released on 2007-11-23 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiology is an area of great recent triumphs in pharmacological and surgical treatment, yet cardiovascular disease remains the leading cause of death and disability in the industrialized world. Coronary disease, heart failure, stroke and sudden arrhythmic cardiac death challenge both medical practitioners and scientists. With the dawning of the new `molecular' era, there is an awakened hope that a more fundamental understanding of biologic processes may eventually lead to new progress in the prevention and treatment of these persistent and seemingly intransigent problems. Molecular Cardiology in Clinical Practice brings together an outstanding panel of experts in cardiovascular disease who have been at the forefront of the application of molecular medicine to cardiology. Its intent is to help bridge the gap between modern medical practice and modern science, in the belief that an understanding of basic principles can lead to new insight into the problems of cardiac patients.

Cellular and Molecular Pathobiology of Cardiovascular Disease

Author : Monte Willis
Publisher : Academic Press
ISBN 13 : 0124055257
Total Pages : 339 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Cellular and Molecular Pathobiology of Cardiovascular Disease by : Monte Willis

Download or read book Cellular and Molecular Pathobiology of Cardiovascular Disease written by Monte Willis and published by Academic Press. This book was released on 2013-12-23 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology

Post-Genomic Cardiology

Author : José Marín-García
Publisher : Academic Press
ISBN 13 : 0124046428
Total Pages : 935 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Post-Genomic Cardiology by : José Marín-García

Download or read book Post-Genomic Cardiology written by José Marín-García and published by Academic Press. This book was released on 2014-05-09 with total page 935 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome, comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA. Offers updated discussion of cutting-edge molecular techniques including new genomic sequencing / NGS / Hap-Map / bioinformatics / systems biology approaches Analyzes mitochondria dynamics and their role in cardiac dysfunction, up-to-date analysis of cardio-protection, and cardio-metabolic syndrome Presents recent translational studies, gene therapy, transplantation of stem cells, and pharmacological treatments in CVDs

Molecular Cardiology in Clinical Practice

Author : Michael R. Sanders
Publisher : Springer Science & Business Media
ISBN 13 : 0585381410
Total Pages : 234 pages
Book Rating : 4.5/5 (853 download)

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Book Synopsis Molecular Cardiology in Clinical Practice by : Michael R. Sanders

Translational Cardiology

Author : Cam Patterson
Publisher : Springer Science & Business Media
ISBN 13 : 1617798916
Total Pages : 556 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Translational Cardiology by : Cam Patterson

Download or read book Translational Cardiology written by Cam Patterson and published by Springer Science & Business Media. This book was released on 2012-07-04 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.

Molecular and Subcellular Cardiology

Author : S. Sideman
Publisher : Springer Science & Business Media
ISBN 13 : 1461518938
Total Pages : 351 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Molecular and Subcellular Cardiology by : S. Sideman

Download or read book Molecular and Subcellular Cardiology written by S. Sideman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Henry Goldberg Workshops were set up to address the following goals: (1) To foster interdisciplinary interaction between scientists and cardiologists, identify missing links, and catalyze new ideas. (2) To relate basic microscale phenomena to the global, clinically manifested cardiac function. (3) To relate conceptual modeling and quantitative analysis to experimental and clinical data. (4) To encourage international cooperation so as to disperse medical and technological knowhow and lead to better understanding of the cardiac system. The first Henry Goldberg Workshop, held in Haifa in 1984, introduced the concept of interaction between cardiac mechanics, electrical activation, perfusion, and metabolism, emphasizing imaging in the clinical environment. The second Workshop, in 1985, discussed the same parameters with a slant towards the control aspects. The third Goldberg Workshop, held in the USA at Rutgers University in 1986, highlighted the transformation of the microscale activation phenomena to macroscale activity and performance, relating electrophysiology, energy metabolism, and cardiac mechanics. The fourth Goldberg Workshop, in 1987, continued the effort to elucidate the interactions among the various parameters affecting cardiac performance, with emphasis on the ischemic heart. The fifth Workshop, held in Cambridge, UK, in 1988, dwelt on the effects of inhomogeneity of the cardiac muscle on its performance in health and disease. The sixth Workshop highlighted the role of new modem imaging techniques, that allow us to gain more insight into local and global cardiac performance in cardiac research and clinical practice.

Molecular Defects in Cardiovascular Disease

Author : Naranjan S. Dhalla
Publisher : Springer Science & Business Media
ISBN 13 : 1441971300
Total Pages : 381 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Molecular Defects in Cardiovascular Disease by : Naranjan S. Dhalla

Download or read book Molecular Defects in Cardiovascular Disease written by Naranjan S. Dhalla and published by Springer Science & Business Media. This book was released on 2011-08-09 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Defects in Cardiovascular Disease provides an in-depth discussion of the molecular mechanisms underlying the genesis of cardiovascular defects and the implications this has on current and emerging targeted therapeutics. Divided into three sections, this book covers the scientific foundations of our present understanding as well as the array of clinical manifestations and their treatment. The first section covers Molecular Mechanisms of Heart Disease, with discussion of the development of cardiovascular dysfunction. The remaining two sections provide a more clinical focus. The second, Cardiac Hypertrophy and Heart Failure deals with metabolic derangements, Ca2+ handling, and subcellular remodeling. It illustrates the wide variety of molecular defects which may serve as targets associated with the transition from cardiac hypertrophy to advanced heart failure. The third section, Hypertension and Diabetes, provides molecular rationale for the pathogenesis of hypertension and diabetic cardiomyopathy, as well as highlighting the importance of hormones toward this end. A necessary resource for clinicians and researchers, this book elucidates the experimental basis of the practice of cardiology. It is the culmination of our advances in the understanding of cardiovascular molecular biology and a blueprint for the efficacious use of targeted therapies.

Congenital Heart Disease

Author : Mary Kearns-Jonker
Publisher : Springer Science & Business Media
ISBN 13 : 159745088X
Total Pages : 281 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Congenital Heart Disease by : Mary Kearns-Jonker

Download or read book Congenital Heart Disease written by Mary Kearns-Jonker and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prominent researchers and clinicians describe in detail all the latest laboratory techniques currently used to define the molecular genetic basis for congenital malformations of the heart, cardiomyopathies, cardiac tumors, and arrythmias in human patients. In particular, the methods can be used to identify in clinical samples those genetic mutations responsible for such congenital abnormalities as Marfan syndrome, Williams-Beuren Syndrome, Alagille syndrome, Noonan syndrome, and Friedreich ataxia. The authors also discuss the limitations of identifying patients with congenital heart disease using these techniques during both pre- and postnatal periods.

Molecular Basis of Cardiovascular Disease

Author : Kenneth R. Chien
Publisher :
ISBN 13 :
Total Pages : 680 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Basis of Cardiovascular Disease by : Kenneth R. Chien

Download or read book Molecular Basis of Cardiovascular Disease written by Kenneth R. Chien and published by . This book was released on 1999 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the molecular basis of heart disease, this text evaluates topics such as genetic mapping approaches in inherited cardiovascular disorders, and driving mechanisms in the transition from cardiac hypertrophy to heart failure.

Molecular Genetics & Gene Therapy of Cardiovascular Diseases

Author : S. C. Mockrin
Publisher : CRC Press
ISBN 13 : 1482273241
Total Pages : 616 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Molecular Genetics & Gene Therapy of Cardiovascular Diseases by : S. C. Mockrin

Download or read book Molecular Genetics & Gene Therapy of Cardiovascular Diseases written by S. C. Mockrin and published by CRC Press. This book was released on 1996-01-02 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides detailed discussions of the most recent developments in gene mapping and manipulation to improve the diagnosis, detection, prevention, and treatment of various cardiovascular diseases--including hypertension, arrhythmias, inherited cariomyopathies, hyperlipidemia, aortic aneurysms, Marfan syndrome, and myocardial infarction. Written by nea

Molecular Biology of Cardiac Development and Growth

Author : Paul J.R. Barton
Publisher : Springer Science & Business Media
ISBN 13 : 3662221926
Total Pages : 280 pages
Book Rating : 4.6/5 (622 download)

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Book Synopsis Molecular Biology of Cardiac Development and Growth by : Paul J.R. Barton

Download or read book Molecular Biology of Cardiac Development and Growth written by Paul J.R. Barton and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the only book to specifically combine basic information on molecular biology with current thinking in cardiac development. The authors clearly illustrate that molecular biology has already provided a wealth of new approaches to the investigation of cellular processes at the molecular level and is now making a significant contribution to the understanding of the role played by such mechanisms in cardiac development. Furthermore, it is shown that this rapidly-expanding field provides an insight into the molecular events underlying cardiac malformation and disease.

Cardiovascular Diseases

Author : Y. Robert Li
Publisher : John Wiley & Sons
ISBN 13 : 0470915374
Total Pages : 501 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Cardiovascular Diseases by : Y. Robert Li

Download or read book Cardiovascular Diseases written by Y. Robert Li and published by John Wiley & Sons. This book was released on 2015-04-06 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management of individual cardiovascular diseases. • Integrates fundamentals and recent advances regarding cardiovascular drugs, blending basic and clinical sciences needed to effectively understand and treat cardiovascular diseases • Facilitates understanding of drug action and mechanism by covering physiology / pathophysiology and pharmacology • Includes guidelines and algorithms for pharmacotherapeutic management of cardiovascular diseases • Uses case presentations and study questions to enhance understanding of the material • Serves as a resource for pharmaceutical and medical students and researchers interested in cardiovascular issues

From Molecule to Men

Author : M. Zehender
Publisher : Springer Science & Business Media
ISBN 13 : 3642577245
Total Pages : 264 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis From Molecule to Men by : M. Zehender

Download or read book From Molecule to Men written by M. Zehender and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: From molecule to man: Medical research has indeed taken this direction, and major improvements of our understanding of the pathophysiology and epidemiology of disease have been achieved. The molecular basis of the congenital cardiovascular disorders has been extended from relatively few congenital malformations into everyday illnesses such as diabetes mellitus, hyperlipoproteinaemea, and arterial hypertension. The monogenic and, more difficult, polygenic basis for a vast majority of cardiovascular disorders are being defined more precisely from year to year. This book gives an overview of what has been achieved so far and defines the current position.