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Molecular Biology Of Collagen Matrix In The Heart
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Book Synopsis Molecular Biology of Collagen Matrix in the Heart by : Mahboubeh Eghbali-Webb
Download or read book Molecular Biology of Collagen Matrix in the Heart written by Mahboubeh Eghbali-Webb and published by Springer. This book was released on 1995-01-20 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the molecular and cellular biology of the collagen matrix of the heart. It is now recognized that the remodeling of the fibrillar collagen matrix that occurs under various pathophysiological conditions may adversely alter myocardial stiffness and ultimately lead to heart failure. This book begins with a comprehensive introductory chapter on the collagen matrix in general, including information on collagen types and their tissue specificity. The book then focuses on different aspects of the molecular and cellular biology of the collagen matrix in the heart, the impact of growth factors on the expression of the myocardial collagen matrix, and myocardial collagen gene regulation under pathophysiological conditions.
Book Synopsis Molecular Biology of Collagen Matrix in the Heart by : Mahboubeh Eghbali-Webb
Download or read book Molecular Biology of Collagen Matrix in the Heart written by Mahboubeh Eghbali-Webb and published by R G Landes Company. This book was released on 1995 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work explores the molecular and cellular biology of the collagen matrix of the heart. Collagen is the major protein of the extracellular matrix. The extracellular matrix of the heart is an intricate network, with its importance becoming apparent to the developmental and functional integrity of the mycardium.
Book Synopsis Hypertension and the Heart by : Alberto Zanchetti
Download or read book Hypertension and the Heart written by Alberto Zanchetti and published by Springer. This book was released on 2012-10-21 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the International Conference held as Part of the Menarinei Series on Cardiovascular Diseases in Berlin, Germany, February 27-28, 1998
Book Synopsis Extracellular Matrix Genes by : Charles Boyd
Download or read book Extracellular Matrix Genes written by Charles Boyd and published by Elsevier. This book was released on 2012-12-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular Matrix Genes provides some of the interesting complexities of the structure of the entire family of extracellular matrix genes. This book illustrates the permanent role that molecular biology and molecular genetics play in the detailed understanding of the normal biology of extracellular matrix. Organized into 10 chapters, this book begins with an overview of the structural and sequence aspects of the entire family of genomic sequences with a view to establishing common functional domains among collagens and their genes. This text then examines the status of the literature concerning human types. III and V. Other chapters consider the FACIT collagen gene family. This book discusses as well the development in understanding the structure of small proteoglycan core proteins and their role in proteoglycan biosynthesis and function as a result of their molecular cloning and expression. The final chapter deals with mutations in collagen genes. This book is a valuable resource for biochemists.
Book Synopsis Connective Tissue Disease by : Jouni Uitto
Download or read book Connective Tissue Disease written by Jouni Uitto and published by CRC Press. This book was released on 1986-10-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of works that canvass many of the recent developments in various areas of connective tissue research. It focuses on the structure of the components, molecular organization and pathology of the extracellular matrix.
Book Synopsis Connective Tissue Matrix by : David W. L. Hukins
Download or read book Connective Tissue Matrix written by David W. L. Hukins and published by . This book was released on 1984 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Structure and Function of Collagen Types by : Richard Mayne
Download or read book Structure and Function of Collagen Types written by Richard Mayne and published by . This book was released on 1987 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Extracellular Matrix Assembly and Structure by : Peter D. Yurchenco
Download or read book Extracellular Matrix Assembly and Structure written by Peter D. Yurchenco and published by Academic Press. This book was released on 1994-03-30 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complex and critical process of extracellular matrix (ECM) assembly is described in this book. Assembly may involve molecules interacting with molecules of the same matrix class, such as in collagen, or interactions between different ECM molecules, such as in basement membranes. The text shows how this is driven by structural information within the matrix monomer. This information will be of interest to cell, developmental, and molecular biologists, biochemists, biophysicists, and biomedical researchers involved in macromolecular assembly, biological macromolecules, and extracellular matrix. Key Features * Addresses assembly of most of the known classes of extracellular matrix macromolecules * Discusses higher order structures produced by ECM * Gives important concepts in: * ECM and cell-matrix interactions * Protein structure and protein-protein interactions * Development and tissue remodeling
Book Synopsis Cardiac Extracellular Matrix by : Eric G. Schmuck
Download or read book Cardiac Extracellular Matrix written by Eric G. Schmuck and published by Springer. This book was released on 2019-10-18 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM's role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.
Book Synopsis Molecular Biology of Collagen Matrix in the Heart by : Mahboubeh Eghbali-Webb
Download or read book Molecular Biology of Collagen Matrix in the Heart written by Mahboubeh Eghbali-Webb and published by Springer. This book was released on 1995-01-20 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the molecular and cellular biology of the collagen matrix of the heart. It is now recognized that the remodeling of the fibrillar collagen matrix that occurs under various pathophysiological conditions may adversely alter myocardial stiffness and ultimately lead to heart failure. This book begins with a comprehensive introductory chapter on the collagen matrix in general, including information on collagen types and their tissue specificity. The book then focuses on different aspects of the molecular and cellular biology of the collagen matrix in the heart, the impact of growth factors on the expression of the myocardial collagen matrix, and myocardial collagen gene regulation under pathophysiological conditions.
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Principles of Tissue Engineering by : Robert Lanza
Download or read book Principles of Tissue Engineering written by Robert Lanza and published by Elsevier. This book was released on 2000-05-16 with total page 1039 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features* Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves* Essential to anyone working in the field* Educates and directs both the novice and advanced researcher* Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves* Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell* Considered the definitive reference in the field* List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others
Book Synopsis Biochemistry of Collagens, Laminins and Elastin by : Morten Karsdal
Download or read book Biochemistry of Collagens, Laminins and Elastin written by Morten Karsdal and published by Academic Press. This book was released on 2016-07-29 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease. Provides a comprehensive introduction to collagen and structural proteins Provides insight into emerging analytical technologies that can detect biomarkers of extracellular matrix degradation Includes a chapter dedicated to the biomarkers of structural proteins Contains insights into the biochemical interactions and changes to structural composition of proteins in disease states
Book Synopsis The Role of Matrix Metalloproteinase in Human Body Pathologies by : Francesco Travascio
Download or read book The Role of Matrix Metalloproteinase in Human Body Pathologies written by Francesco Travascio and published by BoD – Books on Demand. This book was released on 2017-12-20 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Matrix metalloproteinases (MMPs) are a family of proteolytic zinc-containing enzymes involved in physiological as well as in pathological processes in the human organism. MMPs play a key role in the remodeling of the extracellular matrix. Such a process may occur because of tissue homeostasis, morphogenesis, and tissue repair. However, remodeling could also be a part of many pathological states such as arthritis, cardiovascular diseases, neurodegenerative diseases, or impaired development in congenital anomalies. This book overviews the role of MMPs in different pathologies affecting the human body.
Book Synopsis Renin Angiotensin System and the Heart by : Walmor C. De Mello
Download or read book Renin Angiotensin System and the Heart written by Walmor C. De Mello and published by John Wiley & Sons. This book was released on 2005-10-31 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have shown that the heart possesses an intrinsic renin angiotensin system that is controlled by tissue-specific parameters that are activated by biomechanical stress. This book reviews the latest information on the way in which both the plasma and cardiac renin angiotensin systems affect heart function. It covers the cell and molecular biology of these systems, with contributions on renin synthesis, uptake and the intracellular signalling pathways. Particular insight comes from transgenic mouse models in which either mouse or human genes for various components of the renin angiotensin system are expressed. Other topics covered include wound healing as well as the trophic effects of aldosterone. Contains the most recent findings on the renin angiotensin system and the heart Written by an international team of distinguished scientists Covers both the cellular and molecular basis of the renin angiotensin system and the clinical relevance of this research
Book Synopsis Cardiac Remodeling by : Bodh I. Jugdutt
Download or read book Cardiac Remodeling written by Bodh I. Jugdutt and published by Springer Science & Business Media. This book was released on 2013-02-15 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last 2 to 3 decades under one cover and touch on future directions. It provides a high profile and valuable publication resource on molecular mechanisms of cardiac remodeling for both the present and future generations of researchers, teachers, students and trainees. This book should stimulate future translational research targeted towards discovery and development for preventing, limiting and reversing bad remodeling over the next few decades, with the ultimate goal of preventing progression to systolic and/or diastolic heart failure. The chapters suggest potential novel strategies that should receive attention for translating basic research knowledge to application in patients at the bedside.
Book Synopsis Calcific Aortic Valve Disease by : Elena Aikawa
Download or read book Calcific Aortic Valve Disease written by Elena Aikawa and published by BoD – Books on Demand. This book was released on 2013-06-12 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.
