Molecular and Cellular Mechanisms of Heart Failure: Pathophysiology, pathogenesis and therapeutics

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Publisher : Frontiers Media SA
ISBN 13 : 2832533183
Total Pages : 187 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Molecular and Cellular Mechanisms of Heart Failure: Pathophysiology, pathogenesis and therapeutics by : Kenneth Scott Campbell

Download or read book Molecular and Cellular Mechanisms of Heart Failure: Pathophysiology, pathogenesis and therapeutics written by Kenneth Scott Campbell and published by Frontiers Media SA. This book was released on 2023-09-06 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cellular and Molecular Pathobiology of Cardiovascular Disease

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Publisher : Academic Press
ISBN 13 : 0124055257
Total Pages : 339 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Cellular and Molecular Pathobiology of Cardiovascular Disease by : Monte Willis

Download or read book Cellular and Molecular Pathobiology of Cardiovascular Disease written by Monte Willis and published by Academic Press. This book was released on 2013-12-23 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology

Heart Failure

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Publisher : LWW
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Heart Failure by : Arnold M. Katz

Download or read book Heart Failure written by Arnold M. Katz and published by LWW. This book was released on 2009 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Second Edition of Dr. Katz's highly acclaimed text has been thoroughly revised to incorporate the latest advances in the study and treatment of heart failure. the book explains the pathophysiology, molecular mechanisms, clinical manifestations, and therapy of heart failure in a reader-friendly manner that is accessible to both clinicians and basic scientists. This edition includes new information on management of arrhythmias, new research on the roles of rest and exercise in cardiac function, and new guidelines for the organization of heart failure management clinics. the chapters on ther

Congestive Heart Failure

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Publisher :
ISBN 13 :
Total Pages : 888 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Congestive Heart Failure by : Jeffrey D. Hosenpud

Download or read book Congestive Heart Failure written by Jeffrey D. Hosenpud and published by . This book was released on 2000 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now thoroughly revise and updated -- and with many renowned new contributors -- the Second Edition of this highly acclaimed text is the most complete, current, and authoritative reference on congestive heart failure. The book is written by the leaders in the field and covers every aspect of congestive heart failure, from molecular and cellular biology to pathophysiology, diagnosis, and treatment. This edition reflects numerous major developments in the study of the pathogenesis of heart failure and in therapy. The timely coverage also includes cost-effectiveness issues in diagnosis and treatment, as well as a greater emphasis on clinical epidemiology. Nine entirely new chapters focus on key areas such as progression from left ventricular hypertrophy to heart failure; remodeling of the heart after myocardial infarction; cardia interstitium and its role in the pathogenesis of heart failure; cytokine activity; management of atrial arrhythmias; and surgical treatment of heart failure.

Heart Failure in the Child and Young Adult

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Publisher : Academic Press
ISBN 13 : 0128026138
Total Pages : 824 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Heart Failure in the Child and Young Adult by : John L Jefferies

Download or read book Heart Failure in the Child and Young Adult written by John L Jefferies and published by Academic Press. This book was released on 2017-12-05 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart Failure in the Child and Young Adult: From Bench to Bedside combines multiple etiologies for pediatric heart failure, including congenital heart disease, cardiomyopathies, infectious diseases and metabolic abnormalities. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure, then progresses through diagnosis, management, treatment and surgery, finally concluding with advanced special topics, including genetics, self-management and nanomedicine. Provides coverage of the basic science of heart failure, its epidemiology and economic aspects, outpatient and inpatient management, and advanced therapies, including mechanical circulatory support and heart transplantation Combines cutting-edge research with current guidelines from the field

Dilated Cardiomyopathy

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Publisher : Springer
ISBN 13 : 303013864X
Total Pages : 241 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Dilated Cardiomyopathy by : Gianfranco Sinagra

Download or read book Dilated Cardiomyopathy written by Gianfranco Sinagra and published by Springer. This book was released on 2019-05-17 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up. Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice. Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease.

Pathophysiology of Heart Failure

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Publisher : Springer Science & Business Media
ISBN 13 : 1461312353
Total Pages : 578 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Pathophysiology of Heart Failure by : Naranjan S. Dhalla

Download or read book Pathophysiology of Heart Failure written by Naranjan S. Dhalla and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathophysiology of Heart Failure brings together leading basic scientists and clinicians, presenting new approaches to this complex problem, involving cardiomyopathic processes and ischemia perfusion injury. The result is a synthesis of state-of-the-art information on molecular biology, cellular physiology and structure-function relationships in the cardiovascular system. The role which excess intracellular calcium plays in the genesis of cardiac dysfunction is described as a fundamental mechanism underlying heart failure; one which may lead to improved prevention and treatment. Audience: Clinical and experimental cardiologists will find the book a helpful source of ideas and inspiration.

Calcific Aortic Valve Disease

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Publisher : BoD – Books on Demand
ISBN 13 : 9535111507
Total Pages : 544 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Calcific Aortic Valve Disease by : Elena Aikawa

Download or read book Calcific Aortic Valve Disease written by Elena Aikawa and published by BoD – Books on Demand. This book was released on 2013-06-12 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

Heart Failure: A Companion to Braunwald's Heart Disease E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323609880
Total Pages : 784 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Heart Failure: A Companion to Braunwald's Heart Disease E-Book by : G. Michael Felker

Download or read book Heart Failure: A Companion to Braunwald's Heart Disease E-Book written by G. Michael Felker and published by Elsevier Health Sciences. This book was released on 2019-02-06 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date, authoritative and comprehensive, Heart Failure, 4th Edition, provides the clinically relevant information you need to effectively manage and treat patients with this complex cardiovascular problem. This fully revised companion to Braunwald’s Heart Disease helps you make the most of new drug therapies such as angiotensin receptor neprilysin inhibitors (ARNIs), recently improved implantable devices, and innovative patient management strategies. Led by internationally recognized heart failure experts Dr. G. Michael Felker and Dr. Douglas Mann, this outstanding reference gives health care providers the knowledge to improve clinical outcomes in heart failure patients. Focuses on a clinical approach to treating heart failure, resulting from a broad variety of cardiovascular problems. Covers the most recent guidelines and protocols, including significant new updates to ACC, AHA, and HFSA guidelines. Covers key topics such as biomarkers and precision medicine in heart failure and new data on angiotensin receptor neprilysin inhibitors (ARNIs). Contains four new chapters: Natriuretic Peptides in Heart Failure; Amyloidosis as a Cause of Heart Failure; HIV and Heart Failure; and Neuromodulation in Heart Failure. Covers the pathophysiological basis for the development and progression of heart failure. Serves as a definitive resource to prepare for the ABIM’s Heart Failure board exam. 2016 British Medical Association Award: First Prize, Cardiology (3rd Edition).

Molecular and Cellular Mechanisms of Preeclampsia

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Publisher :
ISBN 13 : 9783036525297
Total Pages : 402 pages
Book Rating : 4.5/5 (252 download)

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Book Synopsis Molecular and Cellular Mechanisms of Preeclampsia by : Berthold Huppertz

Download or read book Molecular and Cellular Mechanisms of Preeclampsia written by Berthold Huppertz and published by . This book was released on 2022 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue on the “Molecular and Cellular Mechanisms of Preeclampsia” belongs to the section “Molecular Pathology, Diagnostics, and Therapeutics” of the International Journal of Molecular Sciences. It was a very successful Special Issue as it contains 20 published papers, including one editorial, nine original research papers, and ten reviews on the topic. The original publications cover a wide spectrum of topics, including alterations and involvement of specific factors during preeclampsia, new non-invasive technologies to identify changes, new treatment options, animal models, gender aspects, and effects of the pregnancy pathology later in life. The review publications again cover a wide spectrum of topics, including factors and pathways involved in preeclampsia, effects on the maternal vascular and immune systems, effects on the placenta and the trophoblast, epigenetic changes, new preventive strategies, and new views on the current hypotheses on preeclampsia. Taken together, this Special Issue gives a fantastic overview on a broad spectrum of topics, all of which are important to identify the real etiology of preeclampsia and to finally develop real treatment options.

Molecular Pathology

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Publisher : Academic Press
ISBN 13 : 0128027878
Total Pages : 802 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular Pathology by : William B. Coleman

Download or read book Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2017-11-09 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases

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Publisher : National Academies Press
ISBN 13 : 0309211093
Total Pages : 560 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases by : Institute of Medicine

Download or read book Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.

Oxidative Stress and Redox Regulation

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Publisher : Springer Science & Business Media
ISBN 13 : 9400757875
Total Pages : 488 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Oxidative Stress and Redox Regulation by : Ursula Jakob

Download or read book Oxidative Stress and Redox Regulation written by Ursula Jakob and published by Springer Science & Business Media. This book was released on 2013-03-15 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.

Targeting Cellular Signalling Pathways in Lung Diseases

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Publisher : Springer Nature
ISBN 13 : 9813368276
Total Pages : 926 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Targeting Cellular Signalling Pathways in Lung Diseases by : Kamal Dua

Download or read book Targeting Cellular Signalling Pathways in Lung Diseases written by Kamal Dua and published by Springer Nature. This book was released on 2021-07-02 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by :

Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Pathophysiology and Pharmacotherapy of Cardiovascular Disease

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Publisher : Springer
ISBN 13 : 3319159615
Total Pages : 1342 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Pathophysiology and Pharmacotherapy of Cardiovascular Disease by : Gowraganahalli Jagadeesh

Download or read book Pathophysiology and Pharmacotherapy of Cardiovascular Disease written by Gowraganahalli Jagadeesh and published by Springer. This book was released on 2015-05-06 with total page 1342 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. It provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. In addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease.

Diabetes and Heart Failure: Pathogenesis and Novel Therapeutic Approaches

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889458512
Total Pages : 122 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Diabetes and Heart Failure: Pathogenesis and Novel Therapeutic Approaches by : Celestino Sardu

Download or read book Diabetes and Heart Failure: Pathogenesis and Novel Therapeutic Approaches written by Celestino Sardu and published by Frontiers Media SA. This book was released on 2019-05-15 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: