Molecular and Cellular Biology of Diabetes Mellitus: Insulin action

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Publisher :
ISBN 13 : 9780845142585
Total Pages : 228 pages
Book Rating : 4.1/5 (425 download)

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Book Synopsis Molecular and Cellular Biology of Diabetes Mellitus: Insulin action by : Boris Draznin

Download or read book Molecular and Cellular Biology of Diabetes Mellitus: Insulin action written by Boris Draznin and published by . This book was released on 1989 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular and Cellular Biology of Diabetes Mellitus

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Publisher :
ISBN 13 :
Total Pages : 260 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular and Cellular Biology of Diabetes Mellitus by : Boris Draznin

Download or read book Molecular and Cellular Biology of Diabetes Mellitus written by Boris Draznin and published by . This book was released on 1989 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular and Cell Biology of Type 2 Diabetes and Its Complications

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805566441
Total Pages : 270 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Molecular and Cell Biology of Type 2 Diabetes and Its Complications by : Francesco Belfiore

Download or read book Molecular and Cell Biology of Type 2 Diabetes and Its Complications written by Francesco Belfiore and published by Karger Medical and Scientific Publishers. This book was released on 1998-01-01 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume summarizes current research on type 2 diabetes, its etiology, pathogenesis and long-term vascular and neurological consequences, with special emphasis on molecular and biochemical mechanisms. Alterations in insulin secretion are comprehensively treated, focusing on the role of glucokinase as glucose sensor. Moreover, insulin action is analyzed with regard to both nonoxidative glucose utilization and glucose oxidation. Concerning the complications in chronic diabetes, topics covered include the effects of high glucose concentration on cellular and endothelial functions and on the glucose phosphorylation rate in non-insulin-sensitive tissues. Furthermore, the role of oxidative stress and advanced glycation end products as well as the significance of alterations in lipoprotein structure are considered. Finally, the pericyte loss in retinopathy and microalbuminuria as related to cardiovascular risk are discussed. Taken as a whole, the contributions included in this book represent a large body of information that will be of great interest to diabetologists, endocrinologists and internists interested in both the basic and clinical aspects of diabetes and its complications.

Molecular and Cellular Biology of Diabetes Mellitus: Insulin secretion

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Publisher :
ISBN 13 : 9780845142578
Total Pages : 198 pages
Book Rating : 4.1/5 (425 download)

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Book Synopsis Molecular and Cellular Biology of Diabetes Mellitus: Insulin secretion by : Boris Draznin

Download or read book Molecular and Cellular Biology of Diabetes Mellitus: Insulin secretion written by Boris Draznin and published by . This book was released on 1989 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Insulin Action

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Publisher : Springer Science & Business Media
ISBN 13 : 1461556473
Total Pages : 189 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Insulin Action by : Ashok K. Srivastava

Download or read book Insulin Action written by Ashok K. Srivastava and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.

Molecular Biology of Diabetes

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Publisher : Springer Science & Business Media
ISBN 13 : 1461202418
Total Pages : 411 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Molecular Biology of Diabetes by : Boris Draznin

Download or read book Molecular Biology of Diabetes written by Boris Draznin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a rapidly evolving and extremely important area of medical science, it is often difficult for the student, teacher, and researcher to keep abreast of all the important advances. The purpose of Molecular Biology ofDiabetes, Parts I and II is to bring to these individuals the latest knowledge of diabetes-related research in a comprehensive, yet concise manner. To this end, we have assembled chapters, written by most of the world's experts in the field, that we believe compre hensively survey and synthesize a coherent understanding of the subject. Studies of the etiology of type I and type II diabetes are extremely exciting and essential, since we hope to one day prevent the disease using gene therapy. These aspects are covered in Molecular Biology of Diabetes: I. Autoimmunity and Genetics; Insulin Synthesis and Secretion. In type II diabetes, an abnormality in pancreatic secretion exists concomitantly with peripheral insulin resistance. This abnor mality of insulin secretion is believed to be related to a defect(s) in glucose sensing. Uncoupling of glucose sensing from insulin secre tion may be the crucial step in the pathogenesis of noninsulin-depen dent diabetes. In this volume, we have invited authors to describe their studies on all known factors affecting ~-cell function, including autoimmunity and genetics of diabetes, as well as molecular mecha nisms of insulin synthesis and secretion. In the last few years, the most rapidly advancing area of research in diabetes has been, in fact, related to insulin action.

Mechanisms of Insulin Action

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Publisher : Springer Science & Business Media
ISBN 13 : 0387722041
Total Pages : 223 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Mechanisms of Insulin Action by : Alan R. Saltiel

Download or read book Mechanisms of Insulin Action written by Alan R. Saltiel and published by Springer Science & Business Media. This book was released on 2007-10-05 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.

Molecular and Cellular Biology of Diabetes Mellitus: Complications of diabetes mellitus

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Publisher :
ISBN 13 :
Total Pages : 192 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular and Cellular Biology of Diabetes Mellitus: Complications of diabetes mellitus by : Boris Draznin

Download or read book Molecular and Cellular Biology of Diabetes Mellitus: Complications of diabetes mellitus written by Boris Draznin and published by . This book was released on 1989 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of Diabetes, Part II

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Publisher : Humana
ISBN 13 : 9780896032873
Total Pages : 556 pages
Book Rating : 4.0/5 (328 download)

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Book Synopsis Molecular Biology of Diabetes, Part II by : Boris Draznin

Download or read book Molecular Biology of Diabetes, Part II written by Boris Draznin and published by Humana. This book was released on 1994-11-16 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: These comprehensive yet concise collections of articles by world experts survey the latest findings on the molecular biology of diabetes and insulin action and synthesize a coherent understanding of the subject. Topics include the etiology of type I and type II diabetes, molecular and cellular aspects of insulin action, and the mechanism of the insulin-stimulated glucose uptake.

Molecular Biology of Diabetes, Part II

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Publisher : Humana
ISBN 13 : 9780896032873
Total Pages : 584 pages
Book Rating : 4.0/5 (328 download)

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Book Synopsis Molecular Biology of Diabetes, Part II by : Boris Draznin

Download or read book Molecular Biology of Diabetes, Part II written by Boris Draznin and published by Humana. This book was released on 1994-11-16 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: These comprehensive yet concise collections of articles by world experts survey the latest findings on the molecular biology of diabetes and insulin action and synthesize a coherent understanding of the subject. Topics include the etiology of type I and type II diabetes, molecular and cellular aspects of insulin action, and the mechanism of the insulin-stimulated glucose uptake.

Diabetes and the Endocrine Pancreas

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Publisher : Springer Science & Business Media
ISBN 13 : 9401163790
Total Pages : 168 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Diabetes and the Endocrine Pancreas by : W. Montague

Download or read book Diabetes and the Endocrine Pancreas written by W. Montague and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book attempts to explore the contribution that biochemistry has made, thus far, to our understanding of the endocrine pancreas and its relationship to diabetes mellitus. It was written with the aim of using an important clinical problem to illustrate, to medical students, that there are many aspects of the biochemistry taught in the early years which have direct relevance to clinical medicine. Furthermore, it is hoped that such information might provide biochemistry students with a frame work on which to base further studies. To this end a selection of recent references has been placed at the end of each chapter. In spite of considerable advances in our understanding of diabetes mellitus, it is still a disease which many physicians do not seem to com prehend. This is in part related to their lack of understanding of the molecular biology of the disease. Advances in this area have been dramatic in recent years and we are now able to offer a molecular basis for a rational approach to therapy. It may be therefore that this book will provide some physicians with the information they require to help them gain a deeper understanding of the disease. I hope that everyone who reads this book is able to capture some of the fascination that the islets of Langerhans hold for myself and the many other workers actively engaged in trying to unravel their mys teries.

Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors

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Publisher : Springer Science & Business Media
ISBN 13 : 1468456857
Total Pages : 505 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors by : Derek Leroith

Download or read book Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors written by Derek Leroith and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential element in the development and functional integrity of all organisms is intercellular communication. This is achieved by the secretion of soluble messenger molecules which subsequently interact with receptor-effector pathways in the responsive cells. Hormones are traditionally defined as chemical messengers synthesized by endocrine glands. Unlike hormones produced by endocrine glands, growth factors are hormone-related substances produced by many tissues and play an important role in controlling growth and development. While the exact physiological roles of growth factors have yet to be elucidated, they play important roles in the regulation of cellular proliferation and/or differentiation during ontogenesis, growth and differentiation. During recent years there has been a substantial increase in research related to peptide growth factors, their receptors, and modes of action. With the discovery and characterization of numerous growth factors, it became clear that these growth factors had multiple features in common with classic hormones as well as with oncogenes. Furthermore, there are distinct families of growth factors based either on structural or functional similarities.

Diabetes Mellitus

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781740975
Total Pages : 1606 pages
Book Rating : 4.7/5 (49 download)

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Book Synopsis Diabetes Mellitus by : Derek LeRoith

Download or read book Diabetes Mellitus written by Derek LeRoith and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 1606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program.

Molecular and Cell Biology of Type 2 Diabetes and Its Complications

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Publisher :
ISBN 13 : 9783318002720
Total Pages : 0 pages
Book Rating : 4.0/5 (27 download)

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Book Synopsis Molecular and Cell Biology of Type 2 Diabetes and Its Complications by : G. M. Molinatti

Download or read book Molecular and Cell Biology of Type 2 Diabetes and Its Complications written by G. M. Molinatti and published by . This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume summarizes current research on type 2 diabetes, its etiology, pathogenesis and long-term vascular and neurological consequences, with special emphasis on molecular and biochemical mechanisms. Alterations in insulin secretion are comprehensively treated, focusing on the role of glucokinase as glucose sensor. Moreover, insulin action is analyzed with regard to both nonoxidative glucose utilization and glucose oxidation. Concerning the complications in chronic diabetes, topics covered include the effects of high glucose concentration on cellular and endothelial functions and on the glucose phosphorylation rate in non-insulin-sensitive tissues. Furthermore, the role of oxidative stress and advanced glycation end products as well as the significance of alterations in lipoprotein structure are considered. Finally, the pericyte loss in retinopathy and microalbuminuria as related to cardiovascular risk are discussed. Taken as a whole, the contributions included in this book represent a large body of information that will be of great interest to diabetologists, endocrinologists and internists interested in both the basic and clinical aspects of diabetes and its complications.

Insulin

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Publisher : IRL Press
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Insulin by : Frances M. Ashcroft

Download or read book Insulin written by Frances M. Ashcroft and published by IRL Press. This book was released on 1992 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes is caused by a partial or total lack of the hormone insulin, and is one of the world's major health problems. This book provides an accessible introduction to the current research into all aspects of the synthesis and action of insulin. In the last few years, there have been a number of crucial developments in the study of insulin at the molecular level. These are presented along with discussions of the pathology of diabetes, providing the first integrated account of insulin's physiological action and its significance in disease. Chapters have been assembled from a range of experts in the field, covering topics such as the insulin gene, insulin biosynthesis and secretion, the insulin receptor, and the genetic and immunological aspects of diabetes. Insulin: Molecular Biology to Pathology has been designed with the non-specialist in mind, and includes an extensive glossary of terms. It will enable both researchers and clinicians to gain new insights into unfamiliar areas and will be useful to anyone with an interest in this fascinating hormone.

Molecular Basis of Insulin Action

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Publisher : Springer Science & Business Media
ISBN 13 : 1468448749
Total Pages : 467 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Molecular Basis of Insulin Action by : Michael P. Czech

Download or read book Molecular Basis of Insulin Action written by Michael P. Czech and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: One day, in a moment of weakness, I fell prey to the temptation to organize and edit this volume on the mechanism of insulin action. The major reason for attempting to resist, of course, is the amazing speed at which advances are being made in this field. The usefulness of books such as this is often quickly compromised by new findings obtained during and just after publication. Happily for the contributors to this volume and myself, this unfortunate fate does not appear to be in store for us. New and important findings will undoubtedly continue to flow in this field during the next few years, but I believe this will increase rather than decrease the usefulness of this volume. As a matter of fact, as we go to press, I am delighted both that I was tempted and that I failed to resist. There are two basic reasons for my enthusiasm about this book, and they both relate to this issue of timeliness. First, each of the contributors has had an opportunity to update the scientific content of the various chapters only a few months before actual publication of this volume. The material presented in this volume is, at publication, contemporary with the current original literature. This volume thus provides an ex cellent framework for assessing new discoveries in this field for some time to come.

Diabetes Mellitus in Children

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Publisher :
ISBN 13 : 9781416027539
Total Pages : 0 pages
Book Rating : 4.0/5 (275 download)

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Book Synopsis Diabetes Mellitus in Children by : Mark A. Sperling

Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: