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Author : Roochi Trikha
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (111 download)
Download or read book Molecular Analysis of the Human Immunodeficiency Virus Type 1 Rev Pathway written by Roochi Trikha and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David McDonald
Publisher :
ISBN 13 :
Total Pages : 290 pages
Book Rating : 4.:/5 (58 download)
Download or read book Molecular Analysis of HIV-1 Rev written by David McDonald and published by . This book was released on 1993 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alok Mohan Mulky
Publisher :
ISBN 13 :
Total Pages : 338 pages
Book Rating : 4.:/5 (717 download)
Download or read book Molecular Analysis of the Human Immunodeficiency Virus Type-1 Reverse Transcriptase in Infectious Virus written by Alok Mohan Mulky and published by . This book was released on 2005 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sarah Ashelford
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (42 download)
Download or read book Molecular and Functional Analysis of Human Immunodeficiency Virus Type 1 ENV Genes written by Sarah Ashelford and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John William Dubay
Publisher :
ISBN 13 :
Total Pages : 410 pages
Book Rating : 4.:/5 (289 download)
Download or read book Molecular Analysis of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein written by John William Dubay and published by . This book was released on 1993 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : William A. Haseltine
Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 568 pages
Book Rating : 4.3/5 (91 download)
Download or read book Genetic Structure and Regulation of HIV written by William A. Haseltine and published by Raven Press (ID). This book was released on 1991 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on a conference sponsored by the Harvard AIDS Institute, this volume examines the control of gene expression of the human immunodeficiency virus type 1 (HIV-1), the human T cell leukemia virus types 1 and 2 (HTLV-1 and 2) and related retroviruses.
Author : Kallesh Danappa Jayappa
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (135 download)
Download or read book Molecular Analysis of the Contributions of Human Immunodeficiency Virus Type-1 Integrase in Post Entry Steps of Early Stage Virus Replication written by Kallesh Danappa Jayappa and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Elsevier
ISBN 13 : 0080548326
Total Pages : 488 pages
Book Rating : 4.0/5 (85 download)
Download or read book HIV-1: Molecular Biology and Pathogenesis: Viral Mechanisms written by and published by Elsevier. This book was released on 2007-06-13 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the latest advances in the mechanisms of pathogenesis of the HIV-1 virus on target cells. Its companion volume, Advances in Pharmacology 56, shows how new developments in understanding the virus translate to the clinical setting.
Author :
Publisher : Academic Press
ISBN 13 : 0080549861
Total Pages : 561 pages
Book Rating : 4.0/5 (85 download)
Download or read book HIV I: Molecular Biology and Pathogenesis: Clinical Applications written by and published by Academic Press. This book was released on 2000-09-26 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia. - Detailed insights into viral packaging, expression, and assembly - Mechanistic understanding of how HIV interacts with receptors and infects cells - Delineation of virally encoded regulatory processes unique to HIV - Clinical Applications: - An updated review of current chemotherapeutics for HIV - New concepts in the discovery and design of novel anti-HIV drugs - The latest developments in HIV-vaccine research
Author : Richard W. Lu
Publisher :
ISBN 13 :
Total Pages : 450 pages
Book Rating : 4.:/5 (157 download)
Download or read book Genetic Analysis of Human Immunodeficiency Virus Type 1 Integrase Mutants written by Richard W. Lu and published by . This book was released on 2005 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Guido Silvestri
Publisher : Springer
ISBN 13 : 303002816X
Total Pages : 253 pages
Book Rating : 4.0/5 (3 download)
Download or read book HIV-1 Latency written by Guido Silvestri and published by Springer. This book was released on 2018-10-11 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
Author : Mark J. Sercovich
Publisher :
ISBN 13 :
Total Pages : 90 pages
Book Rating : 4.:/5 (227 download)
Download or read book Human Immunodeficiency Virus Type 1 (HIV-1) Viral Protein R (Vpr)-mediated Cell Cycle Arrest written by Mark J. Sercovich and published by . This book was released on 2006 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human immunodeficiency virus type I (HIV-1) infection causes acquired immunodeficiency syndrome (AIDS), the most globally devastating viral disease of the past 25 years. Development of effective HIV-1 preventative and therapeutic regimens have proven exceedingly difficult, as the virus has evolved sophisticated mechanisms for thwarting control efforts. A detailed understanding of HIV-1 molecular biology is therefore necessary in order to generate the effective and inexpensive prevention and treatment strategies required for AIDS pandemic curtailment. HIV-1 optimizes its transmissibility and propagation through continual change and coordination of its components' functions and life cycle processes with one another and with those of cellular components and processes. Comprehending the molecular bases for HIV-1's abilities to manipulate host cell components and processes is key to the identification of the virus's vulnerabilities. This thesis focuses on one identified effect, G2/M cell cycle arrest induction (1-5), of one highly conserved HIV-1 component, viral protein R (Vpr) (6, 7). A mechanistic understanding of this function is important because arrest at this cell cycle stage provides a selective advantage for the virus: transcription from the viral promoter more active during G2, allowing for increased viral replication (8- 14). Other reasons for the selective advantage of G2/M arrest, e.g. prevention or delay of cell death by mitotic catastrophe or apoptosis, are also possible (3, 15-23). Covering scientific publications through November 2005, this thesis explores the state of knowledge of the mechanism(s) underlying Vpr's ability to induce G2/M cell cycle arrest. The author's goal is to provide a disinterested analysis of the available mechanistic models and their supporting data with the hope of being helpful to the reader in some manner.
Author : Steven G.E. Marsh
Publisher : Elsevier
ISBN 13 : 0080542506
Total Pages : 413 pages
Book Rating : 4.0/5 (85 download)
Download or read book The HLA FactsBook written by Steven G.E. Marsh and published by Elsevier. This book was released on 1999-12-13 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclature and methods used for HLA typing. This book will be an invaluable reference for researchers studying the human immune response, for clinicians and laboratory personnel involved in clinical and forensic HLA typing, and for human geneticists, population biologists, and evolutionary biologists interested in HLA genes as markers of human diversity. Introductory chapters provide good general overview of HLA field for novice immunologists and geneticists Up-to-date, complete listing of HLA alleles Invaluable reference resource for immunologists, geneticists, and cell biologists Combines both structural and functional information, which has never been compiled in a single reference book previously Serological specificity of allotypes Identity of material sequenced including ethnic origin Database accession numbers Population distribution Peptide binding specificities T cell epitopes Amino acid sequences of allotypes Key references
Author : Bryan Cullen
Publisher : Oxford University Press
ISBN 13 : 9780199633821
Total Pages : 220 pages
Book Rating : 4.6/5 (338 download)
Download or read book Human Retroviruses written by Bryan Cullen and published by Oxford University Press. This book was released on 1993 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
Author : Ann Arvin
Publisher : Cambridge University Press
ISBN 13 : 1139461648
Total Pages : 1325 pages
Book Rating : 4.1/5 (394 download)
Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Author : Nouri Neamati
Publisher : John Wiley & Sons
ISBN 13 : 1118015363
Total Pages : 710 pages
Book Rating : 4.1/5 (18 download)
Download or read book HIV-1 Integrase written by Nouri Neamati and published by John Wiley & Sons. This book was released on 2011-08-10 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.
Author : Anthony S. Fauci
Publisher : Springer Science & Business Media
ISBN 13 : 3642608671
Total Pages : 159 pages
Book Rating : 4.6/5 (426 download)
Download or read book Immunopathogenesis of HIV Infection written by Anthony S. Fauci and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last 5 years, major advances have been made in our understanding of the pathogenesis of human immunodeficiency virus (HIV) disease and in the development of new potent antiviral agents. With regard to HIV pathogenesis, several recent observations have not only changed our perspectives of HIV disease, but have been critical for the design of therapeutic strategies.
