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Author : Thomas U. Mayer
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (827 download)
Download or read book Modulated Microtubule Dynamics Enable Hklp2/Kif15 to Assemble Bipolar Spindles written by Thomas U. Mayer and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Frank Kozielski, FSB
Publisher : Springer
ISBN 13 : 9401797323
Total Pages : 276 pages
Book Rating : 4.4/5 (17 download)
Download or read book Kinesins and Cancer written by Frank Kozielski, FSB and published by Springer. This book was released on 2015-03-02 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting the importance of kinesins, summarising current knowledge and how they are shown to be crucial for mitosis. Chapters go on to explore how this family of proteins are emerging as a novel target for chemotherapeutic intervention and drug development. Readers will learn how kinesins travel along microtubules to fulfill their many roles in intracellular transport or cell division. Several compounds that inhibit two mitotic kinesins (called Eg5 and CENP-E) have entered Phase I and II clinical trials and are explored in these chapters. Additional mitotic kinesins are currently being validated as drug targets, raising the possibility that the repertoire of kinesin-based drug targets may expand in the future. The book is suitable as a reference standard for the field of kinesins and cancer. It will interest those in academia and pharmaceutical companies, and anyone with an interest in the medical relevance of these proteins, which cutting edge methodologies are now enabling us to understand in astonishing detail.
Author :
Publisher : ScholarlyEditions
ISBN 13 : 146499482X
Total Pages : 512 pages
Book Rating : 4.4/5 (649 download)
Download or read book Advances in Cytoskeleton Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cytoskeleton Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cytoskeleton. The editors have built Advances in Cytoskeleton Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cytoskeleton in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Cytoskeleton Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Maria Kavallaris
Publisher : Springer Science & Business Media
ISBN 13 : 161779788X
Total Pages : 463 pages
Book Rating : 4.6/5 (177 download)
Download or read book Cytoskeleton and Human Disease written by Maria Kavallaris and published by Springer Science & Business Media. This book was released on 2012-04-23 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cytoskeleton is comprised of a variety of specialized proteins, and is a dynamic structure that is involved in the majority of key cellular events. There is increasing interest in the role of the cytoskeleton in human disease. This volume brings together human disease states where cytoskeletal disruptions are driving disease. Our emerging understanding of the molecular and cellular events that drive cytoskeletal mediated diseases including cancer, heart disease, myopathies and skin disorders, are also helping shape targeted therapeutic approaches to treating these diseases.
Author : J. Richard McIntosh
Publisher : MDPI
ISBN 13 : 3038424021
Total Pages : 341 pages
Book Rating : 4.0/5 (384 download)
Download or read book Mechanisms of Mitotic Chromosome Segregation written by J. Richard McIntosh and published by MDPI. This book was released on 2018-03-23 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Mechanisms of Mitotic Chromosome Segregation" that was published in Biology
Author :
Publisher : Academic Press
ISBN 13 : 0080859348
Total Pages : 757 pages
Book Rating : 4.0/5 (88 download)
Download or read book Xenopus laevis: Practical Uses in Cell and Molecular Biology written by and published by Academic Press. This book was released on 1992-02-03 with total page 757 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the first comprehensive treatment of the wide range of uses for Xenopus laevis oocytes and embryos in cell and molecular biology. Each chapter includes background information, experimental protocols, and suggested applications. An extensive array of techniques is featured. The authors are experienced researchers who have written chapters that will be useful to both experienced researchers and to those new to Xenopus as an experimental system. Full-color plates and diagrams enhance the educational value of this book, which provides a valuable permanent resource for all laboratories that use Xenopus. * Features approximately twenty full-color plates illustrating experimental techniques and results and depicting embryonic development * Provides complete coverage of Xenopus laevis as an experimental system including * Embryonic development, genetics, and laboratory care * Up-to-date protocols for experimental techniques using oocytes and embryos * General information listing recipes, suppliers, sequences, codons, and clones
Author : Sharyn A. Endow
Publisher :
ISBN 13 : 9781383049435
Total Pages : 0 pages
Book Rating : 4.0/5 (494 download)
Download or read book Dynamics of Cell Division written by Sharyn A. Endow and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focussing on the structural aspects of cell division, from nuclear envelope breakdown to cytokinesis, this volume examines spindle assembly and chromosome behaviour, and provides an up-to-date account of developments in this area of cell biology.
Author : Jeremy S. Hyams
Publisher :
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.:/5 (25 download)
Download or read book Mitosis written by Jeremy S. Hyams and published by . This book was released on 1989 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitosis is one of the most fundamental processes in living cells, being common to all eukaryotes, from the simplest plants to the most complex mammals. Its understanding is relevant to virtually every area of biology, ranging from the molecular sciences of cell biology, developmental biology, and genetics to taxonomy and evolutionary studies. Written and compiled by leading authorities, this book reviews the state of mitosis research, discussing cytological, ultrastructural, physical, genetic, and biochemical approaches, and focusing on areas of study that are currently under the most intensive investigation.
Author : John J. Correia
Publisher : Academic Press
ISBN 13 : 0124078885
Total Pages : 472 pages
Book Rating : 4.1/5 (24 download)
Download or read book Microtubules, in vitro written by John J. Correia and published by Academic Press. This book was released on 2013-08-20 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: There continues to be intense interest in the microtubule cytoskeleton; the assembly, structure and regulation of microtubules; and the numerous motors and accessory proteins that control cell cycle, dynamics, organization and transport. The field continues to grow and explore new aspects of these issues driven immensely by developments in optical imaging and tracking techniques. This Second Edition brings together current research and protocols in the field of microtubules in vitro and will serve as a valuable tool for cell biologists, biophysicists and pharmacologists who study the microtubule cytoskeleton, as well as for researchers in the biomedical and biotechnology communities with interest in developing drugs that target microtubules, MAPS and motors. Chapters reflect experimental procedures and new developments in the field of microtubule in vitro research Combines classical approaches and modern technologies Presents easy-to-use protocols and thorough background information, compiled by leaders in the field
