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Modulated Microtubule Dynamics Enable Hklp2 Kif15 To Assemble Bipolar Spindles
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Book Synopsis Advances in Cytoskeleton Research and Application: 2012 Edition by :
Download or read book Advances in Cytoskeleton Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cytoskeleton Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cytoskeleton. The editors have built Advances in Cytoskeleton Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cytoskeleton in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Cytoskeleton Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Kinesins and Cancer by : Frank Kozielski, FSB
Download or read book Kinesins and Cancer written by Frank Kozielski, FSB and published by Springer. This book was released on 2015-03-02 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting the importance of kinesins, summarising current knowledge and how they are shown to be crucial for mitosis. Chapters go on to explore how this family of proteins are emerging as a novel target for chemotherapeutic intervention and drug development. Readers will learn how kinesins travel along microtubules to fulfill their many roles in intracellular transport or cell division. Several compounds that inhibit two mitotic kinesins (called Eg5 and CENP-E) have entered Phase I and II clinical trials and are explored in these chapters. Additional mitotic kinesins are currently being validated as drug targets, raising the possibility that the repertoire of kinesin-based drug targets may expand in the future. The book is suitable as a reference standard for the field of kinesins and cancer. It will interest those in academia and pharmaceutical companies, and anyone with an interest in the medical relevance of these proteins, which cutting edge methodologies are now enabling us to understand in astonishing detail.
Book Synopsis Cytoskeleton and Human Disease by : Maria Kavallaris
Download or read book Cytoskeleton and Human Disease written by Maria Kavallaris and published by Springer Science & Business Media. This book was released on 2012-04-23 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cytoskeleton is comprised of a variety of specialized proteins, and is a dynamic structure that is involved in the majority of key cellular events. There is increasing interest in the role of the cytoskeleton in human disease. This volume brings together human disease states where cytoskeletal disruptions are driving disease. Our emerging understanding of the molecular and cellular events that drive cytoskeletal mediated diseases including cancer, heart disease, myopathies and skin disorders, are also helping shape targeted therapeutic approaches to treating these diseases.
Book Synopsis Xenopus laevis: Practical Uses in Cell and Molecular Biology by :
Download or read book Xenopus laevis: Practical Uses in Cell and Molecular Biology written by and published by Academic Press. This book was released on 1992-02-03 with total page 757 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the first comprehensive treatment of the wide range of uses for Xenopus laevis oocytes and embryos in cell and molecular biology. Each chapter includes background information, experimental protocols, and suggested applications. An extensive array of techniques is featured. The authors are experienced researchers who have written chapters that will be useful to both experienced researchers and to those new to Xenopus as an experimental system. Full-color plates and diagrams enhance the educational value of this book, which provides a valuable permanent resource for all laboratories that use Xenopus.* Features approximately twenty full-color plates illustrating experimental techniques and results and depicting embryonic development* Provides complete coverage of Xenopus laevis as an experimental system including* Embryonic development, genetics, and laboratory care* Up-to-date protocols for experimental techniques using oocytes and embryos* General information listing recipes, suppliers, sequences, codons, and clones
Download or read book Mitosis written by Jeremy S. Hyams and published by . This book was released on 1989 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitosis is one of the most fundamental processes in living cells, being common to all eukaryotes, from the simplest plants to the most complex mammals. Its understanding is relevant to virtually every area of biology, ranging from the molecular sciences of cell biology, developmental biology, and genetics to taxonomy and evolutionary studies. Written and compiled by leading authorities, this book reviews the state of mitosis research, discussing cytological, ultrastructural, physical, genetic, and biochemical approaches, and focusing on areas of study that are currently under the most intensive investigation.
