Modeling Biological Responses Using Gene Expression Profiling And Linear Dynamical Statistical Models

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Computational Methods in Systems Biology

Author : Corrado Priami
Publisher : Springer Science & Business Media
ISBN 13 : 3540006052
Total Pages : 224 pages
Book Rating : 4.5/5 (4 download)

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Book Synopsis Computational Methods in Systems Biology by : Corrado Priami

Download or read book Computational Methods in Systems Biology written by Corrado Priami and published by Springer Science & Business Media. This book was released on 2003-02-07 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rovereto,December2002 CorradoPriami ProgrammeCommitteeofCMSB 2003 CorradoPriami(Chair),UniversityofTrento(Italy), CharlesAu?ray,CNRS,Villejuif(France), CosimaBaldari,Universit`adiSiena(Italy), AlexanderBockmayr,Universit ́eHenriPoincar ́e(France), LucaCardelli,MicrosoftResearchCambridge(UK), VincentDanos,Universit ́eParisVII(France), PierpaoloDegano,Universitad ` iPisa(Italy), Francois ̧ Fages,INRIA,Rocquencourt(France), DrabløsFinn,NorwegianUniversityofScienceandTechnology,Trondheim(N- way), MonikaHeiner,BrandenburgUniversityofTechnologyatCottbus(Germany), InaKoch,UniversityofAppliedSciencesBerlin,(Germany), JohnE.

Dissertation Abstracts International

Author :
Publisher :
ISBN 13 :
Total Pages : 946 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2008 with total page 946 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Systems Biology and In-Depth Applications for Unlocking Diseases

Author : Babak Sokouti
Publisher : Elsevier
ISBN 13 : 0443223270
Total Pages : 356 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Systems Biology and In-Depth Applications for Unlocking Diseases by : Babak Sokouti

Download or read book Systems Biology and In-Depth Applications for Unlocking Diseases written by Babak Sokouti and published by Elsevier. This book was released on 2024-11-05 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biology and In-Depth Applications for Unlocking Diseases: Principles, tools and Application to Disease provides the essence of systems biology approaches in a practical manner, illustrating the basic principles essential to develop and model in real life science applications. Methodologies covered show how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment. Sections provide an introduction and history of systems biology, discuss the tools and resources needed for structure and function of biological systems, and present evidence of systems biology in action. Examples include big data techniques, scale networks, mathematical model development, and much more. This is the perfect reference to provide the fundamental base of knowledge needed for systems biologists, professionals in systems medicine, computational biologists, and bioinformaticians. - Provides detailed and comprehensive coverage of the field of systems biology - Delivers instruction on how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment - Makes effective steps towards personalized medicine in the treatment of disease - Explains effective disease treatment strategies at early diagnosis stages

Computational Methods in Systems Biology

Author :
Publisher :
ISBN 13 :
Total Pages : 236 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Computational Methods in Systems Biology by :

Download or read book Computational Methods in Systems Biology written by and published by . This book was released on 2003 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Probabilistic Boolean Networks

Author : Ilya Shmulevich
Publisher : SIAM
ISBN 13 : 0898716926
Total Pages : 276 pages
Book Rating : 4.8/5 (987 download)

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Book Synopsis Probabilistic Boolean Networks by : Ilya Shmulevich

Download or read book Probabilistic Boolean Networks written by Ilya Shmulevich and published by SIAM. This book was released on 2010-01-21 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive treatment of probabilistic Boolean networks, unifying different strands of current research and addressing emerging issues.

Fitting Models to Biological Data Using Linear and Nonlinear Regression

Author : Harvey Motulsky
Publisher : Oxford University Press
ISBN 13 : 9780198038344
Total Pages : 352 pages
Book Rating : 4.0/5 (383 download)

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Book Synopsis Fitting Models to Biological Data Using Linear and Nonlinear Regression by : Harvey Motulsky

Download or read book Fitting Models to Biological Data Using Linear and Nonlinear Regression written by Harvey Motulsky and published by Oxford University Press. This book was released on 2004-05-27 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most biologists use nonlinear regression more than any other statistical technique, but there are very few places to learn about curve-fitting. This book, by the author of the very successful Intuitive Biostatistics, addresses this relatively focused need of an extraordinarily broad range of scientists.

Computational Methods in Systems Biology

Author : Monika Heiner
Publisher : Springer
ISBN 13 : 3540885625
Total Pages : 413 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Computational Methods in Systems Biology by : Monika Heiner

Download or read book Computational Methods in Systems Biology written by Monika Heiner and published by Springer. This book was released on 2008-10-05 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 6th International Conference on Computational Methods in Systems Biology, CMSB 2008, held in Rostock, Germany, in September 2008. The 21 revised full papers presented together with the summaries of 5 invited papers were carefully reviewed and selected from more than 60 submissions. The papers cover theoretical or applied contributions that are motivated by a biological question focusing on modeling approaches, including process algebra, simulation approaches, analysis methods, in particular model checking and flux analysis, and case studies.

Statistical Diagnostics for Cancer

Author : Matthias Dehmer
Publisher : John Wiley & Sons
ISBN 13 : 3527665455
Total Pages : 301 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Statistical Diagnostics for Cancer by : Matthias Dehmer

Download or read book Statistical Diagnostics for Cancer written by Matthias Dehmer and published by John Wiley & Sons. This book was released on 2012-11-28 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This ready reference discusses different methods for statistically analyzing and validating data created with high-throughput methods. As opposed to other titles, this book focusses on systems approaches, meaning that no single gene or protein forms the basis of the analysis but rather a more or less complex biological network. From a methodological point of view, the well balanced contributions describe a variety of modern supervised and unsupervised statistical methods applied to various large-scale datasets from genomics and genetics experiments. Furthermore, since the availability of sufficient computer power in recent years has shifted attention from parametric to nonparametric methods, the methods presented here make use of such computer-intensive approaches as Bootstrap, Markov Chain Monte Carlo or general resampling methods. Finally, due to the large amount of information available in public databases, a chapter on Bayesian methods is included, which also provides a systematic means to integrate this information. A welcome guide for mathematicians and the medical and basic research communities.

Advances in Neural Information Processing Systems 17

Author : Lawrence K. Saul
Publisher : MIT Press
ISBN 13 : 9780262195348
Total Pages : 1710 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Advances in Neural Information Processing Systems 17 by : Lawrence K. Saul

Download or read book Advances in Neural Information Processing Systems 17 written by Lawrence K. Saul and published by MIT Press. This book was released on 2005 with total page 1710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Papers presented at NIPS, the flagship meeting on neural computation, held in December 2004 in Vancouver.The annual Neural Information Processing Systems (NIPS) conference is the flagship meeting on neural computation. It draws a diverse group of attendees--physicists, neuroscientists, mathematicians, statisticians, and computer scientists. The presentations are interdisciplinary, with contributions in algorithms, learning theory, cognitive science, neuroscience, brain imaging, vision, speech and signal processing, reinforcement learning and control, emerging technologies, and applications. Only twenty-five percent of the papers submitted are accepted for presentation at NIPS, so the quality is exceptionally high. This volume contains the papers presented at the December, 2004 conference, held in Vancouver.

Bayesian Analysis of Gene Expression Data

Author : Bani K. Mallick
Publisher : John Wiley & Sons
ISBN 13 : 9780470742815
Total Pages : 252 pages
Book Rating : 4.7/5 (428 download)

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Book Synopsis Bayesian Analysis of Gene Expression Data by : Bani K. Mallick

Download or read book Bayesian Analysis of Gene Expression Data written by Bani K. Mallick and published by John Wiley & Sons. This book was released on 2009-07-20 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of high-throughput genetic experimentation is evolving rapidly, with the advent of new technologies and new venues for data mining. Bayesian methods play a role central to the future of data and knowledge integration in the field of Bioinformatics. This book is devoted exclusively to Bayesian methods of analysis for applications to high-throughput gene expression data, exploring the relevant methods that are changing Bioinformatics. Case studies, illustrating Bayesian analyses of public gene expression data, provide the backdrop for students to develop analytical skills, while the more experienced readers will find the review of advanced methods challenging and attainable. This book: Introduces the fundamentals in Bayesian methods of analysis for applications to high-throughput gene expression data. Provides an extensive review of Bayesian analysis and advanced topics for Bioinformatics, including examples that extensively detail the necessary applications. Accompanied by website featuring datasets, exercises and solutions. Bayesian Analysis of Gene Expression Data offers a unique introduction to both Bayesian analysis and gene expression, aimed at graduate students in Statistics, Biomedical Engineers, Computer Scientists, Biostatisticians, Statistical Geneticists, Computational Biologists, applied Mathematicians and Medical consultants working in genomics. Bioinformatics researchers from many fields will find much value in this book.

Bioinformatics Using Computational Intelligence Paradigms

Author : Udo Seiffert
Publisher : Springer Science & Business Media
ISBN 13 : 9783540229018
Total Pages : 226 pages
Book Rating : 4.2/5 (29 download)

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Book Synopsis Bioinformatics Using Computational Intelligence Paradigms by : Udo Seiffert

Download or read book Bioinformatics Using Computational Intelligence Paradigms written by Udo Seiffert and published by Springer Science & Business Media. This book was released on 2005-01-17 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics and computational intelligence are undoubtedly remarkably fast growing fields of research and real-world applications with enormous potential for current and future developments. Bioinformatics Using Computational Intelligence Paradigms contains recent theoretical approaches and guiding applications of biologically inspired information processing systems (computational intelligence) against the background of bioinformatics. This carefully edited monograph combines the latest results of bioinformatics and computational intelligence, and offers promising cross-fertilization and interdisciplinary work between these growing fields.

Biocomputing 2006 - Proceedings Of The Pacific Symposium

Author : A Keith Dunker
Publisher : World Scientific
ISBN 13 : 9814479543
Total Pages : 627 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Biocomputing 2006 - Proceedings Of The Pacific Symposium by : A Keith Dunker

Download or read book Biocomputing 2006 - Proceedings Of The Pacific Symposium written by A Keith Dunker and published by World Scientific. This book was released on 2005-12-08 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2006 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2006 will be held January 3-7, 2006 at the Grand Wailea, Maui. Tutorials will be offered prior to the start of the conference.PSB 2006 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Genome Informatics 2007: Genome Informatics Series Vol. 18 - Proceedings Of The 7th Annual International Workshop On Bioinformatics And Systems Biology (Ibsb 2007)

Download Genome Informatics 2007: Genome Informatics Series Vol. 18 - Proceedings Of The 7th Annual International Workshop On Bioinformatics And Systems Biology (Ibsb 2007) PDF Online Free

Author : Satoru Miyano
Publisher : Imperial College Press
ISBN 13 : 190897897X
Total Pages : 348 pages
Book Rating : 4.9/5 (89 download)

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Book Synopsis Genome Informatics 2007: Genome Informatics Series Vol. 18 - Proceedings Of The 7th Annual International Workshop On Bioinformatics And Systems Biology (Ibsb 2007) by : Satoru Miyano

Download or read book Genome Informatics 2007: Genome Informatics Series Vol. 18 - Proceedings Of The 7th Annual International Workshop On Bioinformatics And Systems Biology (Ibsb 2007) written by Satoru Miyano and published by Imperial College Press. This book was released on 2007-12-28 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains 31 peer-reviewed papers based on the presentations at the 7th International Annual Workshop on Bioinformatics and Systems Biology (IBSB 2007) held at the Human Genome Center, Institute of Medical Science, University of Tokyo from July 31 to August 2, 2007. This workshop started in 2001 as an event for doctoral students and young researchers to present and discuss their research results and approaches in bioinformatics and systems biology. It is part of a collaborative educational program involving leading institutions and leaders committed to the following programs and partner institutions:• Boston (Charles DeLisi) — Graduate Program in Bioinformatics, Boston University• Berlin (Herman-Georg Holzhütter) — The International Research Training Group (IRTG) “Genomics and Systems Biology of Molecular Networks”• Kyoto/Tokyo (Minoru Kanehisa/Satoru Miyano) — Joint Bioinformatics Education Program of Kyoto University and University of Tokyo.This volume is dedicated to the memory of Prof. Dr. Dr. h.c. Reinhart Heinrich, a former Professor at Humboldt University Berlin and a co-founder of this workshop./a

Biomolecular Feedback Systems

Author : Domitilla Del Vecchio
Publisher : Princeton University Press
ISBN 13 : 1400850509
Total Pages : 287 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis Biomolecular Feedback Systems by : Domitilla Del Vecchio

Download or read book Biomolecular Feedback Systems written by Domitilla Del Vecchio and published by Princeton University Press. This book was released on 2014-10-26 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an accessible introduction to the principles and tools for modeling, analyzing, and synthesizing biomolecular systems. It begins with modeling tools such as reaction-rate equations, reduced-order models, stochastic models, and specific models of important core processes. It then describes in detail the control and dynamical systems tools used to analyze these models. These include tools for analyzing stability of equilibria, limit cycles, robustness, and parameter uncertainty. Modeling and analysis techniques are then applied to design examples from both natural systems and synthetic biomolecular circuits. In addition, this comprehensive book addresses the problem of modular composition of synthetic circuits, the tools for analyzing the extent of modularity, and the design techniques for ensuring modular behavior. It also looks at design trade-offs, focusing on perturbations due to noise and competition for shared cellular resources. Featuring numerous exercises and illustrations throughout, Biomolecular Feedback Systems is the ideal textbook for advanced undergraduates and graduate students. For researchers, it can also serve as a self-contained reference on the feedback control techniques that can be applied to biomolecular systems. Provides a user-friendly introduction to essential concepts, tools, and applications Covers the most commonly used modeling methods Addresses the modular design problem for biomolecular systems Uses design examples from both natural systems and synthetic circuits Solutions manual (available only to professors at press.princeton.edu) An online illustration package is available to professors at press.princeton.edu

Nutritional Genomics

Author : Wayne R. Bidlack
Publisher : CRC Press
ISBN 13 : 1439844526
Total Pages : 451 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Nutritional Genomics by : Wayne R. Bidlack

Download or read book Nutritional Genomics written by Wayne R. Bidlack and published by CRC Press. This book was released on 2011-12-05 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The notion of matching diet with an individual’s genetic makeup is transforming the way the public views nutrition as a means of managing health and preventing disease. To fulfill the promise of nutritional genomics, researchers are beginning to reconcile the diverse properties of dietary factors with our current knowledge of genome structure and gene function. What is emerging is a complex system of interactions that make the human genome exquisitely sensitive to our nutritional environment. Nutritional Genomics: The Impact of Dietary Regulation of Gene Function on Human Disease provides an integrated view of how genomic and epigenetic processes modulate the impact of dietary factors on health. Written as a resource for researchers, nutrition educators, and policy makers, this book contains the latest scientific findings on the mechanisms of action underlying diet-genome interactions. It presents a unique perspective on the fundamentals of nutritional genomics from genomics, transcriptomics, proteomics, and metabolomics. Contributing authors introduce the important areas of cell signaling and transduction, the intricate regulation of gene expression, and alteration of gene-linked chronic diseases, such as obesity-induced inflammation, insulin resistance, metabolic syndrome, cardiovascular disease, and cancer. The authors detail significant areas of interest within nutritional genomics—including plant-based foods as epigenetic modifiers of gene function and the effects of bioactive phytochemicals on inherited genotype and expressed phenotypes. They also discuss the role of vitamin D in various cancer risks and the gastrointestinal tract as a defense system. Given the key role played by agriculture and the food industry to produce foods to meet personalized health needs, the book also addresses agricultural breeding efforts to enhance nutritional value and the use of technology to increase bioactive ingredients in the food supply. The final chapters discuss manufacturing practices and novel processing techniques for retention of nutrients and bioactive components, as well as the need for regulatory oversight and proper labeling to establish assurance of safety and benefit. An excellent resource for this exciting field, the book identifies future directions for research and opportunities for improving global health and wellness by preventing, delaying, or mitigating chronic diseases with diet.

Hybrid Systems Biology

Author : Alessandro Abate
Publisher : Springer
ISBN 13 : 331926916X
Total Pages : 256 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Hybrid Systems Biology by : Alessandro Abate

Download or read book Hybrid Systems Biology written by Alessandro Abate and published by Springer. This book was released on 2016-01-09 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly referred post-workshop proceedings of the 4th International Workshop on Hybrid Systems biology, HSB 2015, held as part of the Madrid Meet 2015 event, in Madrid, Spain in September 2015. The volume presents 13 full papers together with 2 abstracts of invited sessions from 18 submissions. The scope of the HSB workshop is the general area of dynamical models in Biology with an emphasis on hybrid approaches — by no means restricted to a narrow class of mathematical models — and taking advantage of techniques developed separately in different areas.

Systems Biology

Author : Edda Klipp
Publisher : John Wiley & Sons
ISBN 13 : 3527644997
Total Pages : 593 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Systems Biology by : Edda Klipp

Download or read book Systems Biology written by Edda Klipp and published by John Wiley & Sons. This book was released on 2013-06-20 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: This advanced textbook is tailored to the needs of introductory course in Systems Biology. It has a compagnion website (www.wiley-vch.de/home/systemsbiology)with solutions to questions in the book and several additional extensive working models. The book is related to the very successful previous title 'Systems Biology in Practice' and has incorporated the feedback and suggestions from many lecturers worldwide. The book addresses biologists as well as engineers and computer scientists. The interdisciplinary team of acclaimed authors worked closely together to ensure a comprehensive coverage with no overlaps in a homogenous and compelling style.