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Microwaves In Drug Discovery And Development
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Book Synopsis Microwaves in Drug Discovery and Development by : John Spencer
Download or read book Microwaves in Drug Discovery and Development written by John Spencer and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: There can be little doubt that the introduction of proprietary instrumentation for microwave-assisted synthesis has made a dramatic impact on drug discovery. The uptake of this technology in the field has been rapid and universal, although there remains a number of key challenges, such as difficulties with reaction monitoring, facility for scale-up, and integration with other emerging technologies, as well as key ongoing debates, including the presence (or indeed absence) of specific microwave effects. This book brings together a series of excellent reviews from world-leading groups in the field of microwave-mediated chemistry. Overall, this collection of articles from leading authors from both academia and industry highlights the vital contribution of microwaves in medicinal chemistry and underpins the progress that this technology has made over the past few decades
Book Synopsis Microwaves in Drug Discovery and Development by : John Spencer
Download or read book Microwaves in Drug Discovery and Development written by John Spencer and published by . This book was released on 2014 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Microwaves in Drug Discovery and Development by : John Spencer
Download or read book Microwaves in Drug Discovery and Development written by John Spencer and published by . This book was released on 2014 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: There can be little doubt that the introduction of proprietary instrumentation for microwave-assisted synthesis has made a dramatic impact on drug discovery. The uptake of this technology in the field has been rapid and universal, although there remains a number of key challenges, such as difficulties with reaction monitoring, facility for scale-up, and integration with other emerging technologies, as well as key ongoing debates, including the presence (or indeed absence) of specific microwave effects. This book brings together a series of excellent reviews from world-leading groups in the field of microwave-mediated chemistry. Overall, this collection of articles from leading authors from both academia and industry highlights the vital contribution of microwaves in medicinal chemistry and underpins the progress that this technology has made over the past few decades
Book Synopsis Microwave Assisted Organic Synthesis by : Jason Tierney
Download or read book Microwave Assisted Organic Synthesis written by Jason Tierney and published by John Wiley & Sons. This book was released on 2009-02-12 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first reports on the application of microwaves in organicsynthesis date back to 1986, but it was not until the recentintroduction of specifically designed and constructed equipment,which countered the safety and reproducibility concerns, thatsynthetic application of microwaves has become established as alaboratory technique. Microwave assisted synthesis is now beingadopted in many industrial and academic laboratories to takeadvantage of the novel chemistry that can be carried out using avariety of organic reaction types. This book demonstrates the underlying principles of microwavedielectric heating and, by reference to a range of organic reactiontypes, it's effective use in synthetic organic chemistry. Toillustrate the impact microwave assisted organic synthesis can haveon chemical research, case studies drawn mainly from thepharmaceutical industry are presented.
Book Synopsis Microwaves in Organic and Medicinal Chemistry by : C. Oliver Kappe
Download or read book Microwaves in Organic and Medicinal Chemistry written by C. Oliver Kappe and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors of this guide are experts on the use of microwaves for drug synthesis as well as having much experience in teaching courses held under the auspices of the American Chemical Society and the IUPAC. In this handy source of information for any practicing synthetic chemist they focus on common reaction types in medicinal chemistry, including solid-phase and combinatorial methods. They consider the underlying theory, latest developments in microwave applications and include a variety of examples from recent literature, as well as less common applications that are equally relevant for organic and medicinal chemists. An indispensable reference for researchers with an affinity to modern methods.
Book Synopsis Development of Packaging and Products for Use in Microwave Ovens by : Peter Pesheck
Download or read book Development of Packaging and Products for Use in Microwave Ovens written by Peter Pesheck and published by Elsevier. This book was released on 2009-07-30 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The efficient design of microwave food products and associated packaging materials for optimum food quality and safety requires knowledge of product dielectric properties and associated heating mechanisms, careful consideration of product geometry, knowledge of modern packaging and ingredient technologies, and application of computer simulation, statistics and experimental design. Integrated knowledge and efficient application of these tools is essential for those developing food products in this demanding field. Development of packaging and products for use in microwave ovens provides a focused and comprehensive review for developers. Part one discusses the principles of microwave heating and ovens, with an emphasis on the effect of food dielectric properties and geometry on heating uniformity and optimising the flavours and colours of microwave foods. Microwave packaging materials and design are discussed in Part two; chapters cover rigid packaging, susceptors and shielding. Product development, food, packaging and oven safety is the topic of Part three. Computer modelling of microwave products and active packaging is discussed in Part four. Written by a distinguished team of international contributors, Development of packaging and products for use in microwave ovens is a valuable resource for those in the food and packaging industries. Comprehensively reviews the principles of microwave heating and ovens assessing the effect of food dielectric properties on heating uniformity Thoroughly reviews microwave packaging materials and design including testing and regulatory issues Features a seven page section of colour diagrams to show heat distributions
Book Synopsis Microwaves in Organic and Medicinal Chemistry by : C. Oliver Kappe
Download or read book Microwaves in Organic and Medicinal Chemistry written by C. Oliver Kappe and published by John Wiley & Sons. This book was released on 2013-03-19 with total page 683 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tailored to the needs of medicinal and natural products chemists, the second edition of this unique handbook brings the contents up to speed, almost doubling the amount of chemical information with an additional volume. As in the predecessor, a short introductory section covers the theoretical background and evaluates currently available instrumentation and equipment. The main part of the book then goes on to systematically survey the complete range of published microwave-assisted synthesis methods from their beginnings in the 1990s to mid-2011, drawing on data from more than 5,000 reports and publications. Throughout, the focus is on those reactions, reagents and reaction conditions that work, and that are the most relevant for medicinal and natural products chemistry. A much expanded section is devoted to combinatorial, highthroughput and flow chemistry methods.
Book Synopsis Microwave Chemistry by : Giancarlo Cravotto
Download or read book Microwave Chemistry written by Giancarlo Cravotto and published by Walter de Gruyter GmbH & Co KG. This book was released on 2017-09-25 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microwave Chemistry has changed the way to work in chemical laboratories and is an established state-of-the-art technology to accelarate and enhance chemical processes. This book not only gives an overview of the technology, its historical development and theoretical background, but also presents its exceptionally broad spectrum of applications. Microwave Chemistry enables graduate students and scientist to learn and apply its methods successfully.
Book Synopsis Microwaves in Chemistry Applications by : Aparna Das
Download or read book Microwaves in Chemistry Applications written by Aparna Das and published by Elsevier. This book was released on 2021-05-09 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microwaves in Chemistry Applications: Fundamentals, Methods and Future Trends offers a number of benefits over conventional heating technologies, including acceleration of reaction rates, milder reaction conditions, higher chemical yields, lower energy usage and different reaction selectivity, all of which can improve the sustainability of processes. The book provides valuable insights into the underlying chemistry at play in microwave-assisted processes, introducing fundamental concepts, discussing the modeling of reactions in such processes, and also highlighting a range of key methods and applications of microwaves in chemistry for improved sustainability. Beginning with an introduction to microwave chemistry, Part One discusses foundational principles, equipment and approaches for modeling reactions and assessing the outputs of those models. Methods in microwave chemistry are then the focus of Part Two, with microwave-assisted synthesis, catalysis, reduction and reactions all explored in detail. Part Three reflects on the practical usage of these methods to address specific issues, covering a number of interesting applications. Provides guidance on the modeling and interpretation of microwave effects Discusses microwave chemistry in the context of green chemistry principles Outlines a range of important microwave methods, including microwave-assisted synthesis, catalysis, reactions and reductions
Book Synopsis New Applications of NMR in Drug Discovery and Development by : Leoncio Garrido
Download or read book New Applications of NMR in Drug Discovery and Development written by Leoncio Garrido and published by Royal Society of Chemistry. This book was released on 2013 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a review of recent developments in NMR applications in pharmaceutical research. Consideration is given to consolidated and emerging techniques and methods, many of which are not yet widely applied but are likely to provide new opportunities for drug design. The first part of the book is dedicated to the description of NMR as a tool for the analysis of chemicals and their interactions with targets. The next seven chapters describe NMR approaches to investigate in vivo models of interest in drug discovery and development, with the attention focused on anatomy, function, metabolism and molecular-cellular aspects. Finally, consideration is given to the application of in vivo NMR to the identification and characterization of biomarkers with the aim of monitoring the outcome of therapeutic intervention in selected human diseases, including the study of drug metabolism and toxicity. Aimed at NMR spectroscopists, pharmacologists, imaging researchers and pharmaceutical scientists, this title is invaluable at putting NMR in context within its role in drug discovery and development. This resource is essential reading for those both new and already active in these areas.
Book Synopsis Drug Discovery and Development by : Izet Kapetanović
Download or read book Drug Discovery and Development written by Izet Kapetanović and published by BoD – Books on Demand. This book was released on 2011-12-16 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug discovery and development process aims to make available medications that are safe and effective in improving the length and quality of life and relieving pain and suffering. However, the process is very complex, time consuming, resource intensive, requiring multi-disciplinary expertise and innovative approaches. There is a growing urgency to identify and develop more effective, efficient, and expedient ways to bring safe and effective products to the market. The drug discovery and development process relies on the utilization of relevant and robust tools, methods, models, and validated biomarkers that are predictive of clinical effects in terms of diagnosis, prevention, therapy, and prognosis. There is a growing emphasis on translational research, a bidirectional bench to the bedside approach, in an effort to improve the process efficiency and the need for further innovations. The authors in the book discuss the current and evolving state of drug discovery and development.
Book Synopsis Current Trends in Drug Discovery, Development and Delivery (CTD4-2022) by : Manikanta Murahari
Download or read book Current Trends in Drug Discovery, Development and Delivery (CTD4-2022) written by Manikanta Murahari and published by Royal Society of Chemistry. This book was released on 2023-12-15 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is based on peer-reviewed manuscripts from the 2022 Conference on Current Trends in Drug Discovery, Development and Delivery (CTD4-2022) held at KL University, India. Providing a wide range of up to date topics on the latest advancements in drug design and discovery technologies, this book ensures the reader receives a good understanding of the scope of the field. Aimed at scientists, students, regulators, academics and consultants throughout the world, this book is an ideal resource for anyone interested in the state of the art in drug design and discovery.
Book Synopsis Microwave Synthesis by : Brittany L. Hayes
Download or read book Microwave Synthesis written by Brittany L. Hayes and published by . This book was released on 2002 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Introduction to microwave chemistry 11; 2. Solvents 29; 3. Chemical reactions in the presence and absence of solvent 77; 4. Synthetic applications 95; 5. Getting started with microwave synthesis 157; 6. Microwave safety considerations 175; 7. Microwave hardware 181.
Book Synopsis Microwave Assisted Chemistry Experiments by : B. R. Prashantha Kumar
Download or read book Microwave Assisted Chemistry Experiments written by B. R. Prashantha Kumar and published by . This book was released on 2021-09 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Practical Microwave Synthesis for Organic Chemists by : C. Oliver Kappe
Download or read book Practical Microwave Synthesis for Organic Chemists written by C. Oliver Kappe and published by John Wiley & Sons. This book was released on 2008-11-21 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the novice user in mind, this beginner's guide explains thebasics behind microwave technology, evaluates available instrumentsand reaction modes, and provides practical hints for everyeventuality. Includes 27 detailed protocols for often-usedreactions. From the contents: 1 Microwave Synthesis - An Introduction 2 Microwave Theory 3 Equipment Review 4 Microwave Processing Techniques 5 Starting With Microwave Chemistry 6 Experimental Protocols 6.1 General Small-Scale Sealed-Vessel Microwave Processing 6.2 Reaction Optimization 6.3 Library Generation 6.4 Reaction Scale-Up 6.5 Special Processing Techniques
Book Synopsis Microwave Methods in Organic Synthesis by : Mats Larhed
Download or read book Microwave Methods in Organic Synthesis written by Mats Larhed and published by Springer Science & Business Media. This book was released on 2006-10-09 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are delighted to present this volume with contributions from some of the most renowned and experienced microwavechemists today. The delivery and introduction of energy has been closely connected with the discovery and investigation of new chemistry. It is with pleasure that we have seen an increased use of microwave irradiation over the years and we hope that this volume will re?ect the current interest in expanding the scopeofmicrowaveapplicationsinbothorganicandmedicinalchemistry. One important explanation behind the growth of microwave-enhanced chemistry has been the introductionof dedicated microwavereactors. As a result of this development we are proud to present a diverse set of - views. Apart fromchapters spanning the scope that is usually associated with microwavemethods, such as heterocyclic chemistry - an intriguing, but fr- tratingly diverse?eld that is excellently presented in one of the reviews - and transition metal-catalyzed reactions, we also present a review on microwa- assisted natural product chemistry, a topic that is of high interest and neither often nor widely covered. A contribution on microwave-accelerated synt- sis of protease inhibitors underlines the usefulness of microwave heating in medicinal chemistryandareview of?uorousmicrowavechemistryhighlights the importance of the combination of high-speed reactions and quick sepa- tions. Two separate chaptersonscaled-up microwavereactionsandgreen and sustainablechemistrygiveanoverviewofaspectsofmicrowavechemistrythat mightbeofgreatuseinbothindustrialandsmall-scaleapplications. We would like to take this opportunity to express our sincere gratitude to the contributors of this volume for their valuable time and efforts. We believe that the presented workwill further promotethe use of controlledmicrowave heating in both academia and industry.
Book Synopsis Microwave Heating as a Tool for Sustainable Chemistry by : Nicholas E. Leadbeater
Download or read book Microwave Heating as a Tool for Sustainable Chemistry written by Nicholas E. Leadbeater and published by CRC Press. This book was released on 2010-09-02 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shorter reaction times, higher product yields, and enhanced selectivity are some of the advantages microwave heating has over conventional methods, causing its use to transition from a curiosity to mainstream, both in industrial and academic settings. Microwave Heating as a Tool for Sustainable Chemistry showcases the application of microwave heati
