Microfluidic Techniques

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Microfluidic Techniques

Author : Shelley D. Minteer
Publisher : Springer Science & Business Media
ISBN 13 : 1592599974
Total Pages : 245 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Microfluidic Techniques by : Shelley D. Minteer

Download or read book Microfluidic Techniques written by Shelley D. Minteer and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hands-on researchers review the principles behind successful miniaturization and describe the key techniques for miniaturizing large-scale biochemical and bioanalytical methods for microchip analysis. The authors cover not only the most popular methods for the fabrication of microchips (photolithography, laser ablation, and soft lithography), but also microfluidic techniques for such bioanalytical assays and bioprocesses as DNA analysis, PCR, immunoassays, and cell reactors. Highlights include PCR on a microchip, microscale cell culturing, and the study of cellular processes on a microchip. The protocols offer step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Laboratory Methods in Microfluidics

Author : Basant Giri
Publisher : Elsevier
ISBN 13 : 0128132361
Total Pages : 178 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Laboratory Methods in Microfluidics by : Basant Giri

Download or read book Laboratory Methods in Microfluidics written by Basant Giri and published by Elsevier. This book was released on 2017-05-15 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Methods in Microfluidics features a range of lab methods and techniques necessary to fully understand microfluidic technology applications. Microfluidics deals with the manipulation of small volumes of fluids at sub-millimeter scale domain channels. This exciting new field is becoming an increasingly popular subject both for research and education in various disciplines of science, including chemistry, chemical engineering and environmental science. The unique properties of microfluidic technologies, such as rapid sample processing and precise control of fluids in assay have made them attractive candidates to replace traditional experimental approaches. Practical for students, instructors, and researchers, this book provides a much-needed, comprehensive new laboratory reference in this rapidly growing and exciting new field of research. Provides a number of detailed methods and instructions for experiments in microfluidics Features an appendix that highlights several standard laboratory techniques, including reagent preparation plus a list of materials vendors for quick reference Authored by a microfluidics expert with nearly a decade of research on the subject

Microfluidics

Author : Yu Song
Publisher : John Wiley & Sons
ISBN 13 : 3527341064
Total Pages : 576 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Microfluidics by : Yu Song

Download or read book Microfluidics written by Yu Song and published by John Wiley & Sons. This book was released on 2018-05-07 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book offering a global overview of fundamental microfluidics and the wide range of possible applications, for example, in chemistry, biology, and biomedical science. As such, it summarizes recent progress in microfluidics, including its origin and development, the theoretical fundamentals, and fabrication techniques for microfluidic devices. The book also comprehensively covers the fluid mechanics, physics and chemistry as well as applications in such different fields as detection and synthesis of inorganic and organic materials. A useful reference for non-specialists and a basic guideline for research scientists and technicians already active in this field or intending to work in microfluidics.

Microfluidic Technologies for Miniaturized Analysis Systems

Author : Steffen Hardt
Publisher : Springer Science & Business Media
ISBN 13 : 0387684247
Total Pages : 630 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Microfluidic Technologies for Miniaturized Analysis Systems by : Steffen Hardt

Download or read book Microfluidic Technologies for Miniaturized Analysis Systems written by Steffen Hardt and published by Springer Science & Business Media. This book was released on 2007-09-29 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses Lab-on-a-Chip devices. It focuses on microfluidic technologies that have emerged in the past decade. Coverage presents a comprehensive listing of the most promising microfluidic technologies in the Lab-on-a-Chip field. It also details technologies that can be viewed as toolboxes needed to set up complex Lab-on-a-Chip systems.

Microfluidic Methods for Molecular Biology

Author : Chang Lu
Publisher : Springer
ISBN 13 : 3319300199
Total Pages : 376 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Microfluidic Methods for Molecular Biology by : Chang Lu

Download or read book Microfluidic Methods for Molecular Biology written by Chang Lu and published by Springer. This book was released on 2016-05-14 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the state-of-the-art research on molecular biology assays and molecular techniques enabled or enhanced by microfluidic platforms. Topics covered include microfluidic methods for cellular separations and single cell studies, droplet-based approaches to study protein expression and forensics, and microfluidic in situ hybridization for RNA analysis. Key molecular biology studies using model organisms are reviewed in detail. This is an ideal book for students and researchers in the microfluidics and molecular biology fields as well as engineers working in the biotechnology industry. This book also: Reviews exhaustively the latest techniques for single-cell genetic, epigenetic, metabolomic, and proteomic analysis Illustrates microfluidic approaches for inverse metabolic engineering, as well as analysis of circulating exosomes Broadens readers’ understanding of microfluidics convection-based PCR technology, microfluidic RNA-seq, and microfluidics for robust mobile diagnostics

Microfluidics for Single-Cell Analysis

Author : Jin-Ming Lin
Publisher : Springer Nature
ISBN 13 : 9813297298
Total Pages : 261 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Microfluidics for Single-Cell Analysis by : Jin-Ming Lin

Download or read book Microfluidics for Single-Cell Analysis written by Jin-Ming Lin and published by Springer Nature. This book was released on 2019-08-28 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the various microfluidic-based approaches for single-cell capture, isolation, manipulation, culture and observation, lysis, and analysis. Single-cell analysis reveals the heterogeneities in morphology, functions, composition, and genetic performance of seemingly identical cells, and advances in single-cell analysis can overcome the difficulties arising due to cell heterogeneity in the diagnostics for a targeted model of disease. This book provides a detailed review of the state-of-the-art techniques presenting the pros and cons of each of these methods. It also offers lessons learned and tips from front-line investigators to help researchers overcome bottlenecks in their own studies. Highlighting a number of techniques, such as microfluidic droplet techniques, combined microfluidics-mass-spectrometry systems, and nanochannel sampling, it describes in detail a new microfluidic chip-based live single-cell extractor (LSCE) developed in the editor’s laboratory, which opens up new avenues to use open microfluidics in single-cell extraction, single-cell mass spectrometric analysis, single-cell adhesion analysis and subcellular operations. Serving as both an elementary introduction and advanced guidebook, this book interests and inspires scholars and students who are currently studying or wish to study microfluidics-based cell analysis methods.

Fundamentals of Microfluidics and Lab on a Chip for Biological Analysis and Discovery

Author : Paul C.H. Li
Publisher : CRC Press
ISBN 13 : 1439882177
Total Pages : 420 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Fundamentals of Microfluidics and Lab on a Chip for Biological Analysis and Discovery by : Paul C.H. Li

Download or read book Fundamentals of Microfluidics and Lab on a Chip for Biological Analysis and Discovery written by Paul C.H. Li and published by CRC Press. This book was released on 2010-02-24 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lab-on-a-chip technology permits us to make many important discoveries that can only be observed at the microscale or the nanoscale. Using this technology, biological and biochemical analyses translate into greater sensitivity, more accurate results, and more valuable findings. Authored by one of the field's pioneering researchers, Fundamentals of

Microfluidics for Biological Applications

Author : Wei-Cheng Tian
Publisher : Springer Science & Business Media
ISBN 13 : 0387094806
Total Pages : 429 pages
Book Rating : 4.3/5 (87 download)

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Book Synopsis Microfluidics for Biological Applications by : Wei-Cheng Tian

Download or read book Microfluidics for Biological Applications written by Wei-Cheng Tian and published by Springer Science & Business Media. This book was released on 2009-03-02 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics for Biological Applications provides researchers and scientists in the biotechnology, pharmaceutical, and life science industries with an introduction to the basics of microfluidics and also discusses how to link these technologies to various biological applications at the industrial and academic level. Readers will gain insight into a wide variety of biological applications for microfluidics. The material presented here is divided into four parts, Part I gives perspective on the history and development of microfluidic technologies, Part II presents overviews on how microfluidic systems have been used to study and manipulate specific classes of components, Part III focuses on specific biological applications of microfluidics: biodefense, diagnostics, high throughput screening, and tissue engineering and finally Part IV concludes with a discussion of emerging trends in the microfluidics field and the current challenges to the growth and continuing success of the field.

Microfluidics

Author : Bastian E. Rapp
Publisher : Elsevier
ISBN 13 : 0128240237
Total Pages : 850 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Microfluidics by : Bastian E. Rapp

Download or read book Microfluidics written by Bastian E. Rapp and published by Elsevier. This book was released on 2022-10-07 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics: Modeling, Mechanics and Mathematics, Second Edition provides a practical, lab-based approach to nano- and microfluidics, including a wealth of practical techniques, protocols and experiments ready to be put into practice in both research and industrial settings. This practical approach is ideally suited to researchers and R&D staff in industry. Additionally, the interdisciplinary approach to the science of nano- and microfluidics enables readers from a range of different academic disciplines to broaden their understanding. Alongside traditional fluid/transport topics, the book contains a wealth of coverage of materials and manufacturing techniques, chemical modification/surface functionalization, biochemical analysis, and the biosensors involved. This fully updated new edition also includes new sections on viscous flows and centrifugal microfluidics, expanding the types of platforms covered to include centrifugal, capillary and electro kinetic platforms. Provides a practical guide to the successful design and implementation of nano- and microfluidic processes (e.g., biosensing) and equipment (e.g., biosensors, such as diabetes blood glucose sensors) Provides techniques, experiments and protocols that are ready to be put to use in the lab, or in an academic or industry setting Presents a collection of 3D-CAD and image files on a companion website

Microfluidics and Lab-on-a-Chip

Author : Andreas Manz
Publisher : Royal Society of Chemistry
ISBN 13 : 1782628339
Total Pages : 307 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Microfluidics and Lab-on-a-Chip by : Andreas Manz

Download or read book Microfluidics and Lab-on-a-Chip written by Andreas Manz and published by Royal Society of Chemistry. This book was released on 2020-09-24 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Responding to the need for an affordable, easy-to-read textbook that introduces microfluidics to undergraduate and postgraduate students, this concise book will provide a broad overview of the important theoretical and practical aspects of microfluidics and lab-on-a-chip, as well as its applications.

Particles Separation in Microfluidic Devices

Author : Takasi Nisisako
Publisher : MDPI
ISBN 13 : 3039366947
Total Pages : 230 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis Particles Separation in Microfluidic Devices by : Takasi Nisisako

Download or read book Particles Separation in Microfluidic Devices written by Takasi Nisisako and published by MDPI. This book was released on 2020-12-10 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic platforms are increasingly being used for separating a wide variety of particles based on their physical and chemical properties. In the past two decades, many practical applications have been found in chemical and biological sciences, including single cell analysis, clinical diagnostics, regenerative medicine, nanomaterials synthesis, environmental monitoring, etc. In this Special Issue, we invited contributions to report state-of-the art developments in the fields of micro- and nanofluidic separation, fractionation, sorting, and purification of all classes of particles, including, but not limited to, active devices using electric, magnetic, optical, and acoustic forces; passive devices using geometries and hydrodynamic effects at the micro/nanoscale; confined and open platforms; label-based and label-free technology; and separation of bioparticles (including blood cells), circulating tumor cells, live/dead cells, exosomes, DNA, and non-bioparticles, including polymeric or inorganic micro- and nanoparticles, droplets, bubbles, etc. Practical devices that demonstrate capabilities to solve real-world problems were of particular interest.

Digital Microfluidic Biochips

Author : Krishnendu Chakrabarty
Publisher : CRC Press
ISBN 13 : 1420008307
Total Pages : 228 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Digital Microfluidic Biochips by : Krishnendu Chakrabarty

Download or read book Digital Microfluidic Biochips written by Krishnendu Chakrabarty and published by CRC Press. This book was released on 2018-10-03 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.

Methods in Bioengineering

Author : Jeffrey D. Zahn
Publisher : Artech House
ISBN 13 : 1596934018
Total Pages : 367 pages
Book Rating : 4.5/5 (969 download)

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Book Synopsis Methods in Bioengineering by : Jeffrey D. Zahn

Download or read book Methods in Bioengineering written by Jeffrey D. Zahn and published by Artech House. This book was released on 2009-10 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and edited by recognized experts in the field, the new Artech House Methods in Bioengineering series offers detailed guidance on authoritative methods for addressing specific bioengineering challenges. Offering a highly practical presentation of each topic, each book provides research engineers, scientists, and students with step-by-step procedures, clear examples, and effective ways to overcome problems that may be encountered. This unique volume presents leading-edge microfluidics methods used to handle, manipulate, and analyze cells, particles biological components (e.g., proteins and DNA) for microdiagnostics.

Biomedical Applications of Microfluidic Devices

Author : Michael R. Hamblin
Publisher : Academic Press
ISBN 13 : 0128187921
Total Pages : 352 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Biomedical Applications of Microfluidic Devices by : Michael R. Hamblin

Download or read book Biomedical Applications of Microfluidic Devices written by Michael R. Hamblin and published by Academic Press. This book was released on 2020-11-12 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a key role in these areas, which are big drivers in biomedical engineering research. This book addresses the fundamental concepts and fabrication methods of microfluidic systems for those who want to start working in the area or who want to learn about the latest advances being made. The subjects covered are also an asset to companies working in this field that need to understand the current state-of-the-art. The book is ideal for courses on microfluidics, biosensors, drug targeting, and BioMEMs, and as a reference for PhD students. The book covers the emerging and most promising areas of biomedical applications of microfluidic devices in a single place and offers a vision of the future. Covers basic principles and design of microfluidics devices Explores biomedical applications to areas such as tissue engineering, organ-on-a-chip, pathogen identification, and drug and gene delivery Includes chemical applications in organic and inorganic chemistry Serves as an ideal text for courses on microfluidics, biosensors, drug targeting, and BioMEMs, as well as a reference for PhD students

Sensing Techniques for Food Safety and Quality Control

Author : Xiaonan Lu
Publisher : Royal Society of Chemistry
ISBN 13 : 1782626646
Total Pages : 383 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Sensing Techniques for Food Safety and Quality Control by : Xiaonan Lu

Download or read book Sensing Techniques for Food Safety and Quality Control written by Xiaonan Lu and published by Royal Society of Chemistry. This book was released on 2017-07-14 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an updated summary of the application of different types of sensors for the analysis of food safety and quality, this book discusses the core principles, current research status, challenges and successful examples for each technology. In addition, the prospective and future trends for each topic are covered in each chapter. The editor and contributors are all experts in designing and constructing different types of sensors in food analysis, mainly focusing on the determination of food safety and quality. Sensors, as a new generation of detection technique, have many advantages and the application of sensors in food analysis will continue to grow in the next decades. However, until now, there has been no book providing the detailed characterization and summary of sensors in food safety and quality analysis that this book provides. It is vital reading for academic researchers and practising professionals in Food Science, Agricultural Engineering, Biological Systems Engineering, Food Safety, Food Quality and Food Analysis who are using sensors in their work.

Microfluidic Cell Culture Systems

Author : Christopher Bettinger
Publisher : William Andrew
ISBN 13 : 143773460X
Total Pages : 452 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Microfluidic Cell Culture Systems by : Christopher Bettinger

Download or read book Microfluidic Cell Culture Systems written by Christopher Bettinger and published by William Andrew. This book was released on 2012-12-31 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fields of microfluidics and BioMEMS are significantly impacting cell biology research and applications through the application of engineering solutions to human disease and health problems. The dimensions of microfluidic channels are well suited to the physical scale of biological cells, and the many advantages of microfluidics make it an attractive platform for new techniques in biology. This new professional reference applies the techniques of microsystems to cell culture applications. The authors provide a thoroughly practical guide to the principles of microfluidic device design and operation and their application to cell culture techniques. The resulting book is crammed with strategies and techniques that can be immediately deployed in the lab. Equally, the insights into cell culture applications will provide those involved in traditional microfluidics and BioMEMS with an understanding of the specific demands and opportunities presented by biological applications. The goal is to guide new and interested researchers and technology developers to the important areas and state-of-the-practice strategies that will enhance the efficiency and value of their technologies, devices and biomedical products. Provides insights into the design and development of microfluidic systems with a specific focus on cell culture applications Focuses on strategies and techniques for the design and fabrication of microfluidic systems and devices for cell culture Provides balanced coverage of microsystems engineering and bioengineering

Medical and Industrial Applications of Microfluidic-based Cell/Tissue Culture and Organs-on-a-Chip: Advances in Organs-on-a-Chip and Organoids Technologies

Download Medical and Industrial Applications of Microfluidic-based Cell/Tissue Culture and Organs-on-a-Chip: Advances in Organs-on-a-Chip and Organoids Technologies PDF Online Free

Author : Qasem Ramadan
Publisher : Frontiers Media SA
ISBN 13 : 2889631141
Total Pages : 138 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Medical and Industrial Applications of Microfluidic-based Cell/Tissue Culture and Organs-on-a-Chip: Advances in Organs-on-a-Chip and Organoids Technologies by : Qasem Ramadan

Download or read book Medical and Industrial Applications of Microfluidic-based Cell/Tissue Culture and Organs-on-a-Chip: Advances in Organs-on-a-Chip and Organoids Technologies written by Qasem Ramadan and published by Frontiers Media SA. This book was released on 2019-10-16 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in microfluidics have demonstrated enormous potential of microscale cell culture for biology studies and recognized as instrumental in performing rapid and efficient experiments on small-sample volumes. Microfluidic-based cell culture is an area of research that keeps growing and gaining importance as a prominent technology, able to link scientific disciplines with industrial and clinical applications. In particular, organotypic cell culture and its integration in microfluidic devices would enable the realization of “in vivo-like” cell microenvironment within systems that are more amenable to automation and integration. Such remarkable advancement forms the foundation and motivation to transfer research from the laboratory to the field. Although the microfluidics and cell culture technologies have influenced many areas of science, significant research efforts are currently focus on finding methods to transform drug screening and toxicity testing from a system reliant on high-dose animal studies to one based primarily on human-relevant in vitro models. In line with regulatory developments precluding the use of animal testing, as well as fundamental differences in animal versus human, human in vitro methodologies are required to replace the animal-based testes while permitting physiologically relevant model equivalents for superior prediction. Organs-on-a-chip is an ambitious and rapidly growing technology that promise to bridge the gap between in vivo and in vitro studies and open wide possibilities in medical and industrial applications. However, many challenges are still ahead. This eBook present recent state-of-the-art works and critical reviews in organs-on-a-chip technology which highlight the new advances in this growing field with an emphasis on the interface between technological advancements and high impact applications.