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Microbial Metabolism And Disease
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Book Synopsis Microbial Metabolism and Disease by : Elena L. Paley
Download or read book Microbial Metabolism and Disease written by Elena L. Paley and published by Academic Press. This book was released on 2021-03-13 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiome Metabolic Pathways and Disease provides insight into the interaction of microbial metabolic pathways in the human body and the impact these can have on a variety of diseases. By analyzing these pathways the book seeks to investigate how these metabolic processes can be targeted and manipulated in order to treat various disorders and diseases. Topics covered in the book include microbial shikimate pathways, protein biosynthesis, tryptophan metabolites, microbiome metabolic engineering, fecal microbiota transplantation, and virulence factors. Additionally, a variety of conditions are covered, such as disorders associated with metabolic syndromes, serotonin syndromes, Alzheimer’s disease, and Covid-19, providing a detailed overview of how metabolic pathways of microbiome can impact health and disease in the human body. Explores microbial metabolic pathways in the human body and implications for disease Investigates specific steps involved in metabolic reactions in the human microbiome, including shikimate pathways and tryptophan pathways Considers a variety of diseases and disorders, such as Alzheimer’s disease, metabolic syndromes, Crohn’s disease and Covid-19 Includes analysis of various amino acids and enzymes in microbial and human cells and how these can impact health
Book Synopsis Microbial Metabolism In The Digestive Tract by : M. J. Hill
Download or read book Microbial Metabolism In The Digestive Tract written by M. J. Hill and published by CRC Press. This book was released on 2018-02-01 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book an attempt has been made to give an update on the flora of the human digestive tract and its role in disease. This is a subject that has implications in many disciplines and therefore is aimed at not only microbiologists, but also clinicians, dentists, medical researchers, biochemists, and toxicologists who have a background knowledge of bacteriology but are not necessarily directly involved in research into the metabolic actions of gut bacteria.
Book Synopsis Bacterial Metabolism by : Gerhard Gottschalk
Download or read book Bacterial Metabolism written by Gerhard Gottschalk and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise yet comprehensive text surveys the field of bacterial metabolism in terms useful to students and researchers. Emphasis is on those metabolic reactions occurring only in bacteria. Thus, the book describes in detail the energy metabolism of the various groups of bacteria. In addition, it examines pathways used by bacteria for the degradation of organic compounds, the synthesis of cellular constituents, the regulation of bacterial metabolism and the fixation of molecular nitrogen.
Book Synopsis Bacterial Metabolism by : G. Gottschalk
Download or read book Bacterial Metabolism written by G. Gottschalk and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been written for students who are taking a course in bacterial metabolism. I hope, however, that scholars will also find it useful either as a help in teaching bacterial metabolism or as a review on the special aspects of metabolism in bacteria. The concept of this book results from my experience in teaching bacterial metabolism. In the first chapters the principal reactions of the energy and biosynthetic metabolism have been discussed using Escherichia coli as a model organism. Then the diversity of aerobic metabolism has been out lined. Following a brief description of the regulation of the level and the activity of enzymes in bacteria the characteristic features of fermentative, chemolithotrophic and phototrophic metabolism have been discussed. Finally, the last chapter has been devoted to nitrogen fixation. Throughout the text I have tried not only to describe metabolic pathways and enzyme reactions but also to elucidate the physiology of the microorganisms which carry out all these metabolic reactions. Two comments regarding the formulas used in this book are necessary.
Book Synopsis Host - Pathogen Interaction by : Gottfried Unden
Download or read book Host - Pathogen Interaction written by Gottfried Unden and published by John Wiley & Sons. This book was released on 2016-09-06 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of the rapidity increasing incidence rate of bacterial and fungal infections with multi-resistant pathogens, the metabolic changes associated with host-pathogen interactions offer one of the most promising starting points for developing novel antibiotics. . Part one of this comprehensive guide describes the metabolic adaptation of pathogenic microbes in humans, while part two points to routes for the development of novel antibiotics. This is volume six of the book series on drug discovery in infectious diseases by Paul Selzer.
Book Synopsis Metabolism and Bacterial Pathogenesis by : Tyrrell Conway
Download or read book Metabolism and Bacterial Pathogenesis written by Tyrrell Conway and published by John Wiley & Sons. This book was released on 2015-09-01 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Groundbreaking thinking on how bacterial metabolism is foundational to pathogenesis For too long, bacterial metabolism and bacterial pathogenesis have been studied as separate entities. However, the scientific community is beginning to realize that not only are bacterial nutrient acquisition and utilization essential for pathogenesis, but that interfering with the pathogen-specific metabolic pathways used during infection can regulate virulence factor expression and might lead to effective breakthroughs in a variety of treatments. Editors Paul Cohen and Tyrrell Conway, who pioneered the use of metabolic mutants in competitive colonization assays, an approach now widely used to investigate the nutrition of pathogens in vivo, are uniquely qualified to advance our knowledge of this integrative field of research. They convened a group of contributors who are breaking new ground in understanding how bacterial metabolism is foundational to pathogenesis to share their expert perspectives and outlook for the future. Beginning with overviews, Metabolism and Bacterial Pathogenesis covers a wide range of diseases and both Gram-positive and -negative bacteria that serve as model systems for in vitro and in vivo investigations intracellular, respiratory, and enteric pathogens pathogen-specific nutrient acquisition in hosts mechanisms of host-driven metabolic adaptation by pathogens metabolic regulation of virulence gene expression Useful for specialists in bacterial pathogenesis and specialists in metabolism as well as molecular biologists, physicians, veterinarians, dentists, graduate and undergraduate students, and laboratory technicians, Metabolism and Bacterial Pathogenesis is also essential reading for scientists studying the microbiome.
Book Synopsis The Human Microbiome, Diet, and Health by : Food Forum
Download or read book The Human Microbiome, Diet, and Health written by Food Forum and published by National Academies Press. This book was released on 2013-02-27 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309458390 Total Pages :133 pages Book Rating :4.3/5 (94 download)
Book Synopsis The Chemistry of Microbiomes by : National Academies of Sciences, Engineering, and Medicine
Download or read book The Chemistry of Microbiomes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-07-19 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.
Book Synopsis Introduction to the Microbial World by : Roger Y. Stanier
Download or read book Introduction to the Microbial World written by Roger Y. Stanier and published by Prentice Hall. This book was released on 1979 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: The history of microbiology; The methods of microbiology; The nature of the microbial world; Microbial metabolism; Microbial growth; The relations between structure and function in procaryotic cells; The viruses; Genetics; Taxonomy of cellular microorganisms; The autotrophic propagatory; Cream-negative chemoheterotrophs; Cram-positive bacteria; The protists; Microorganisms as geochemical agents; Symbiosis; Microbial pathogenecity; Microbial diseases of humans; Industrial uses of microorganisms.
Book Synopsis Gut Microbial Response to Host Metabolic Phenotypes by : Jie Yin
Download or read book Gut Microbial Response to Host Metabolic Phenotypes written by Jie Yin and published by Frontiers Media SA. This book was released on 2022-02-23 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metabonomics and Gut Microbiota in Nutrition and Disease by : Sunil Kochhar
Download or read book Metabonomics and Gut Microbiota in Nutrition and Disease written by Sunil Kochhar and published by Springer. This book was released on 2014-10-21 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also examines the translatability of systems biology approaches into applied clinical research and to patient health and nutrition. The rise in multifactorial disorders, the lack of understanding of the molecular processes at play and the needs for disease prediction in asymptomatic conditions are some of the many questions that system biology approaches are well suited to address. Achieving this goal lies in our ability to model and understand the complex web of interactions between genetics, metabolism, environmental factors and gut microbiota. Being the most densely populated microbial ecosystem on earth, gut microbiota co-evolved as a key component of human biology, essentially extending the physiological definition of humans. Major advances in microbiome research have shown that the contribution of the intestinal microbiota to the overall health status of the host has been so far underestimated. Human host gut microbial interaction is one of the most significant human health considerations of the present day with relevance for both prevention of disease via microbiota-oriented environmental protection as well as strategies for new therapeutic approaches using microbiota as targets and/or biomarkers. In many aspects, humans are not a complete and fully healthy organism without their appropriate microbiological components. Increasingly, scientific evidence identifies gut microbiota as a key biological interface between human genetics and environmental conditions encompassing nutrition. Microbiota dysbiosis or variation in metabolic activity has been associated with metabolic deregulation (e.g. obesity, inflammatory bowel disease), disease risk factor (e.g. coronary heart disease) and even the aetiology of various pathologies (e.g. autism, cancer), although causal role into impaired metabolism still needs to be established. Metabonomics and Gut Microbiota in Nutrition and Disease serves as a handbook for postgraduate students, researchers in life sciences or health sciences, scientists in academic and industrial environments working in application areas as diverse as health, disease, nutrition, microbial research and human clinical medicine.
Book Synopsis Microbes, Microbial Metabolism and Mucosal Immunity by : Tanima Bose
Download or read book Microbes, Microbial Metabolism and Mucosal Immunity written by Tanima Bose and published by Academic Press. This book was released on 2023-12-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of microbiome and microbial metabolites and their roles in host mucosal immunology is a rapidly developing area of research. One major way in which the microbiome influences the host is through altered metabolism. Metabolites, readily available to the host, engender significant consequences. Microbial metabolites have been shown to impact the disease processes in both proximal and distal organs, including the brain in several neurocognitive disorders. Microbes, Microbial Metabolism and Mucosal Immunity: An Overview presents a concise and well-vetted treatise on the study of microbiome and microbial metabolites. This volume is up-to-date with the most recent developments from the last decade. It encompasses the interaction of immunity and microbes - and their metabolites - from different mucosal organs including eye, skin, gastrointestinal system, lung, intestine and cervix. Along with the efficiency of the immune system in inhibiting the growth and proliferation of microbes, the volume discusses how the mediators of the immune system can be targeted to develop therapies. This book presents the latest methods, gives broad and systematic coverage of most mucosal systems and diseases, and takes a fresh perspective that looks at the functional aspects of change in the microbiome.
Book Synopsis Regulation of Inflammatory Signaling in Health and Disease by : Dakang Xu
Download or read book Regulation of Inflammatory Signaling in Health and Disease written by Dakang Xu and published by Springer. This book was released on 2018-12-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses recent research in innate immunity, which has revealed a large number of receptors that sense the presence of microorganisms or cellular damage in tissues. In complex tissues, many of these sensing events occur simultaneously. Thus, the downstream signaling pathways need to be integrated so that an appropriate cellular inflammatory response can be initiated. In addition, the inflammasome defines the molecular and cellular processes of inflammation in response to microbial infection. Previous data suggested that regulation of inflammasomes is mediated by microbes, but inflammasomes also have antimicrobial functions. Increasing evidence in mouse models, together with human data, strongly implicates an involvement of the inflammasome and uncontrolled inflammation in the initiation and progression of diseases with a high impact on public health. The book reviews novel aspects of functional genomics, epigenomics, transcriptomics, post-translat ional modifications, microbiome and immunometabolism in order to understand inflammatory signaling and responses, covering recent findings on the mechanisms underlying the regulation of inflammatory responses to pathogens, dysregulation of these responses in inflammatory disease, and the use of such mechanisms to boost or subdue the inflammatory response. Bridging the gaps in understanding between the fields of human and mouse immunology, it provides valuable insights into inflammatory-mediated disease and immune defense. Such innovative perspectives in both basic and clinical research promote the translation of knowledge to the clinic.
Book Synopsis Microbial Biochemistry by : Georges N. Cohen
Download or read book Microbial Biochemistry written by Georges N. Cohen and published by Springer. This book was released on 2016-05-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focusses on microbial physiology, biochemistry and genetics and provides the reader with detailed information on a number of microbial pathways. Insight into microbial biochemistry have allowed for the formulation of concepts that have turned out to be important in the study of higher organisms. In the first section, the principles of bacterial growth are given, as well as a description of the different layers that enclose the bacterial cytoplasm, and their role in obtaining nutrients from the outside media through different permeability mechanism, which are described in detail. A chapter is devoted to allostery, which is indispensable for the comprehension of many regulatory mechanisms described throughout the book. The second section analyses the mechanisms by which cells obtain the energy necessary for their growth; Glycolysis, the pentose phosphate pathway, the tricarboxylic and the anaplerotic cycles. Two chapters are devoted to classes of microorganisms rarely dealt with in textbooks, namely the Archaea, mainly the methanogenic bacteria, and the methylotrophs. Eight chapters describe the principles of regulation at the transcriptional level, with the necessary knowledge of the machineries of transcription and translation. The next fifteen chapters deal with the biosynthesis of the cell building blocks, amino acids, purine and pyrimidine nucleotides and deoxynucleotides, water-soluble vitamins and coenzymes, isoprene and tetrapyrrole derivatives and vitamin B12. The two last chapters are devoted to the study of protein-DNA interactions and to the evolution of biosynthetic pathways. The considerable advances made in the last thirty years in the field by the introduction of gene cloning and sequencing and by the exponential development of physical methods such as X-ray crystallography, nuclear magnetic resonance and cryo-electron microscopy have helped in presenting microbial metabolism as a highly multidisciplinary field of study.
Book Synopsis Volatiles and Metabolites of Microbes by : Ajay Kumar
Download or read book Volatiles and Metabolites of Microbes written by Ajay Kumar and published by Academic Press. This book was released on 2021-06-22 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volatiles and Metabolites of Microbes compiles the latest research and advancement in the field of volatiles, metabolites synthesized from the microbial strains such as actinomycetes, bacteria, cyanobacteria, and fungal species and their potential applications in the field of healthcare issue and sustainable agriculture. There is an urgent need to explore new and advanced biological methods for health industries and sustainable agriculture and to protect the environment from environmental pollution or contaminates, global warming, and also control the health of human beings from the side effects of various pharmaceuticals products. Focusing all these factors, Volatiles and Metabolites of Microbes explores new aspects of microorganism in terms of volatiles, enzymes, bioactive compounds synthesized from the microbes and their potential applications in the field of sustainable agriculture and health-related issues Provides a broad aspect about volatiles, bioactive compounds, and secondary metabolites of microbes compiled in one cover Gives the latest research and advancement in the field of volatiles, secondary metabolites, and bioactive compounds synthesized from the different microbial strains Responds to new developments in the detection of the complex compound structures of volatiles Offers insight to a very broad audience in Biotechnology, Applied Microbiology, Agronomy, and Pathology
Book Synopsis Microbial Metabolism by : H. W. Doelle
Download or read book Microbial Metabolism written by H. W. Doelle and published by . This book was released on 1974 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chemical Microbiology by : A. H. Rose
Download or read book Chemical Microbiology written by A. H. Rose and published by Elsevier. This book was released on 2014-05-20 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Microbiology: An Introduction to Microbial Physiology, Third Edition covers aspects of the chemical activities of microorganisms. The book describes the molecular architecture of microorganisms, the methods used in studying this molecular architecture; and the ways by which microorganisms can respond to and modify their environment. The text also discusses the various environmental factors that influence microbial activity. The book tackles the principles, the strategies employed, and the methods used in the studies of microbial metabolism. The transport of compounds into and out of microorganisms by the solute-transport processes and endocytosis; the principles of bioenergetics and biosynthesis; and the regulation of metabolism are also considered. The book tackles as well the growth, survival and differentiation of microorganisms. Biologists, microbiologists, chemical microbiologists, geneticists, and biochemists will find this book invaluable.
