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Transgenic Mice and Mutants in MHC Research

Author : Igor K. Egorov
Publisher : Springer Science & Business Media
ISBN 13 : 3642754422
Total Pages : 323 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Transgenic Mice and Mutants in MHC Research by : Igor K. Egorov

Download or read book Transgenic Mice and Mutants in MHC Research written by Igor K. Egorov and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains papers presented at the international conference on "Transgenic Mice and Mutants in MHC Research", held in Bar Harbor, Maine, in June, 1989. The meeting brought together eighty researchers working in the field. While mouse H-2 mutants have been known for many years their studies continue to contribute a great deal to our understanding of structure/function relationships and evolution of MHC molecules. Recently a new direction of research has emerged on regulation, expression and function of MHC genes using transgenic animals carrying exogenous MHC genes from the same or other species or engineered MHC genes. With the introduction of transgenic mice more specific questions about the various functions of MHC genes can be answered as, for example, the role of soluble and membrane-bound MHC molecules in self tolerance and elimination of specific T cell clones, recognition of human MHC antigens by the mouse immune system, the role of individual human MHC genes in disease susceptibility. New approaches for evaluation of the role of MHC linked and unlinked genes in susceptibility of mice to malignant tumors and their metastases have been also reported. Our purpose has been to provide a forum for discussion of these new developments. Many questions remain to be answered but the necessary tools have become available. We thank the contributors and hope that the readers will benefit from this Pro ceedings. We wish to acknowledge the financial sponsorship for the meeting by The Pew Charitable Trust and Howard Hughes Medical Institute.

MHC Ligands and Peptide Motifs

Author : Hans-Georg Rammensee
Publisher : Springer Science & Business Media
ISBN 13 : 3662221624
Total Pages : 467 pages
Book Rating : 4.6/5 (622 download)

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Book Synopsis MHC Ligands and Peptide Motifs by : Hans-Georg Rammensee

Download or read book MHC Ligands and Peptide Motifs written by Hans-Georg Rammensee and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is centered on a comprehensive list of MHC peptide motifs and ligands as known to date, together with selected T cell epitopes, arranged in an easy-to-read fashion. This information is put into context by chapters on MHC gene organization, MHC structure, T cell epitope prediction, antigen processing and T cell responses. In addition, the book provides a great deal of complementary information: amino acid sequences of MHC class I alpha1 and alpha2 domains and of class II alpha1 and beta1 domains, the established or predicted composition and specificity of MHC pockets, notes on MHC nomenclature including old assignments and reference to useful internet addresses. A handy reference manual that should be helpful for all those dealing with MHC-associated peptides.

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Major Histocompatibility Complex (MHC) in Health and Disease

Author : Jerzy K. Kulski
Publisher : MDPI
ISBN 13 : 3039280724
Total Pages : 374 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Major Histocompatibility Complex (MHC) in Health and Disease by : Jerzy K. Kulski

Download or read book Major Histocompatibility Complex (MHC) in Health and Disease written by Jerzy K. Kulski and published by MDPI. This book was released on 2020-01-15 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major histocompatibility complex (MHC) is a highly polymorphic and diverse multigene locus in all jawed vertebrate species that has an integral role in adaptive/innate immune systems, transplantation, and infectious and autoimmune diseases. The MHC supra-locus in mammalian vertebrates is usually partitioned into three distinct regions, known as classes I, II, and III, which, to varying extents, can be found conserved in nonmammalian jawed vertebrates, such as bony fish, amphibians, and bird lineages. The MHC gene region is characterized particularly by the expression of class I and class II glycoproteins that bind peptides derived from intracellular or extracellular antigens to circulating T-cells. While this expressed antigenic specificity remains the predominant interest with respect to MHC function and polymorphism in a population, a broader concept has emerged that examines the MHC as a multifunctional polymorphic controller that facilitates and regulates genome diversity with a much greater array of functions and effects than just MHC-restricted antigen recognition. This volume of 19 reprints presented by various experts and collected from the Special Issue of Cells on “MHC in Health and Disease” covers a broad range of topics on the genomic diversity of the MHC regulatory system in various vertebrate species, including MHC class I, II, and III genes; innate and adaptive immunity; neurology; transplantation; haplotypes; infectious and autoimmune diseases; fecundity; conservation; allelic lineages; and evolution. Taken together, these articles demonstrate the immense complexity and diversity of the MHC structure and function within and between different vertebrate species.

Medical Subject Headings

Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1372 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Medical Subject Headings by : National Library of Medicine (U.S.)

Download or read book Medical Subject Headings written by National Library of Medicine (U.S.) and published by . This book was released on 1997 with total page 1372 pages. Available in PDF, EPUB and Kindle. Book excerpt:

La Salud Mental de la Raza

Author : Josephine Arredondo-Holden
Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis La Salud Mental de la Raza by : Josephine Arredondo-Holden

Download or read book La Salud Mental de la Raza written by Josephine Arredondo-Holden and published by . This book was released on 1981 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hodge Theory (MN-49)

Author : Eduardo Cattani
Publisher : Princeton University Press
ISBN 13 : 1400851475
Total Pages : 608 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis Hodge Theory (MN-49) by : Eduardo Cattani

Download or read book Hodge Theory (MN-49) written by Eduardo Cattani and published by Princeton University Press. This book was released on 2014-07-21 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date introduction to Hodge theory—one of the central and most vibrant areas of contemporary mathematics—from leading specialists on the subject. The topics range from the basic topology of algebraic varieties to the study of variations of mixed Hodge structure and the Hodge theory of maps. Of particular interest is the study of algebraic cycles, including the Hodge and Bloch-Beilinson Conjectures. Based on lectures delivered at the 2010 Summer School on Hodge Theory at the ICTP in Trieste, Italy, the book is intended for a broad group of students and researchers. The exposition is as accessible as possible and doesn't require a deep background. At the same time, the book presents some topics at the forefront of current research. The book is divided between introductory and advanced lectures. The introductory lectures address Kähler manifolds, variations of Hodge structure, mixed Hodge structures, the Hodge theory of maps, period domains and period mappings, algebraic cycles (up to and including the Bloch-Beilinson conjecture) and Chow groups, sheaf cohomology, and a new treatment of Grothendieck’s algebraic de Rham theorem. The advanced lectures address a Hodge-theoretic perspective on Shimura varieties, the spread philosophy in the study of algebraic cycles, absolute Hodge classes (including a new, self-contained proof of Deligne’s theorem on absolute Hodge cycles), and variation of mixed Hodge structures. The contributors include Patrick Brosnan, James Carlson, Eduardo Cattani, François Charles, Mark Andrea de Cataldo, Fouad El Zein, Mark L. Green, Phillip A. Griffiths, Matt Kerr, Lê Dũng Tráng, Luca Migliorini, Jacob P. Murre, Christian Schnell, and Loring W. Tu.

Molecular Genetics of Inflammatory Bowel Disease

Author : Charlotte Hedin
Publisher : Springer Nature
ISBN 13 : 3030287033
Total Pages : 399 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Molecular Genetics of Inflammatory Bowel Disease by : Charlotte Hedin

Download or read book Molecular Genetics of Inflammatory Bowel Disease written by Charlotte Hedin and published by Springer Nature. This book was released on 2019-12-19 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reaches out to a wide variety of professionals in the biomedical field with an interest in inflammatory bowel disease (IBD). Enormous progress has been made in the last few years since the publication of the first edition in the study of complex diseases and IBD, with hundreds of genomic regions identified that are associated with increased risk. Authored by leading clinical and research scientists in the field, the book includes state-of-the art synopses of recent genetic findings, and their interpretation for current and future exploitation in translational approaches to personalized medicine in IBD. The book also covers risk prediction, improved diagnostic and therapeutic precision, dissection of disease phenotypes and subtypes, identification of biomarkers, and host gene-microbiota interactions of clinical relevance.

The HLA System in Clinical Transplantation

Author : Bjarte G. Solheim
Publisher : Springer Science & Business Media
ISBN 13 : 3642775063
Total Pages : 431 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The HLA System in Clinical Transplantation by : Bjarte G. Solheim

Download or read book The HLA System in Clinical Transplantation written by Bjarte G. Solheim and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: With this book we· want to address young graduate students, clini cians involved in transplantation, and technicians in transplantation immunology laboratories. The volume should give a comprehensive but basic, up to date introduction to the structure, function, and clinical importance of the HLA system. We believe that there is a need for such a survey, and think that the present level of our knowledge is an optimal occasion for publication. A significant number of ques tions have now been resolved, and our knowledge has reached a level of sophistication that provides the basis for additional questions and answers. Although the emphasis of this book is on the role of HLA anti gens in clinical transplantation, their involvement in other clinical contexts is also discussed. The main focus is on the human MHC an tigenic system, but MHC systems in other species are described as they contribute to our understanding of the structural and functional characteristics of HLA antigens. Some important issues related to laboratory techniques are also covered. The contributors have a close affiliation to the field of transplan tation immunology. A majority have even been playing important roles in unraveling the HLA system and its functions. We believe this has contributed significantly to the quality and clinical and practical relevance of the book. As editors, we drew up the principal guidelines and took care that the chapters can be read as separate entities, although this invariably results in some overlapping.

Textbook of Immunology

Author : Constantin A. Bona
Publisher : CRC Press
ISBN 13 : 1000725227
Total Pages : 456 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Textbook of Immunology by : Constantin A. Bona

Download or read book Textbook of Immunology written by Constantin A. Bona and published by CRC Press. This book was released on 2019-11-11 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on the strengths of the first edition, the newly titled and expanded second edition remains a concise introduction to the fundamentals of immunology, with an expert synthesis of basic and clinical information., Augmented by color illustrations, and with increased emphasis on the molecular and genetic underpinnings of cellular phenomena, Textbook of Immunology covers the physiology of the immune system, disease entities related to immune system dysfunction, and the underlying pathophysiologic mechanisms of dysfunction. In response to advancing knowledge that influences the approach to presenting basic immunology, new chapters have been added on cytokines; host defense (non-specific immunity and specific immune responses); the aging immune system; and the pathophysiology, diagnosis, prevention, and therapy of AIDS., This book keeps pace with the explosion of information and data in immunology, and adeptly refines, organizes, and presents this body of knowledge to serve as a succinct introduction to modern immunologic concepts for medical students, and as an update and refresher in the basics for researchers and clinicians.

The Chemical News and Journal of Physical Science

Author :
Publisher :
ISBN 13 :
Total Pages : 686 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis The Chemical News and Journal of Physical Science by :

Download or read book The Chemical News and Journal of Physical Science written by and published by . This book was released on 1912 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Therapist's Guide to Positive Psychological Interventions

Author : Jeana L. Magyar-Moe
Publisher : Academic Press
ISBN 13 : 0080923011
Total Pages : 230 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Therapist's Guide to Positive Psychological Interventions by : Jeana L. Magyar-Moe

Download or read book Therapist's Guide to Positive Psychological Interventions written by Jeana L. Magyar-Moe and published by Academic Press. This book was released on 2009-07-30 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positive psychology - essentially the scientific study of the strengths that enable individuals and communities to thrive - is a relatively new discipline that has experienced substantial growth in the last 5-10 years. Research suggests that the principles and theories from this area of study are highly relevant to the practice of counseling and psychotherapy, and positive psychology presents clinicians and patients with a much needed balance to the more traditional focus on pathology and the disease model of mental health. This book provides a comprehensive introduction to the best-researched positive psychological interventions. It emphasizes clinical application, providing a detailed view of how the research can be applied to patients. Covering the broaden-and-build theory, strengths-based therapy, mentoring modalities and more, the volume will provide numerous assessment tools, exercises and worksheets for use throughout the counseling and psychotherapy process. - Summarizes the applications of research from positive psychology to the practice of counseling and psychotherapy - Provides clinician a variety of assessments, worksheets, handouts, and take home and in-session exercises to utilize in the process of conducting therapy from a positive psychological perspective - Provides general treatment planning guidelines for the appropriate use of such assessments, worksheets, handouts, and exercises - Bibliography of positive psychology references to compliment the information provided in this book

Chemical News and Journal of Industrial Science

Author :
Publisher :
ISBN 13 :
Total Pages : 448 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Chemical News and Journal of Industrial Science by :

Download or read book Chemical News and Journal of Industrial Science written by and published by . This book was released on 1907 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biochemical, Physiological, and Molecular Aspects of Human Nutrition - E-Book

Author : Martha H. Stipanuk
Publisher : Elsevier Health Sciences
ISBN 13 : 0323266959
Total Pages : 990 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Biochemical, Physiological, and Molecular Aspects of Human Nutrition - E-Book by : Martha H. Stipanuk

Download or read book Biochemical, Physiological, and Molecular Aspects of Human Nutrition - E-Book written by Martha H. Stipanuk and published by Elsevier Health Sciences. This book was released on 2012-03-30 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering advanced nutrition with a comprehensive, easy-to-understand approach, Biochemical, Physiological, and Molecular Aspects of Human Nutrition, 3rd Edition focuses on the biology of human nutrition at the molecular, cellular, tissue, and whole-body levels. It addresses nutrients by classification, and describes macronutrient function from digestion to metabolism. This edition includes the new MyPlate dietary guide and recommendations from the Dietary Guidelines for Americans 2010, plus coverage of the historical evolution of nutrition and information on a wide range of vitamins, minerals, and other food components. In Biochemical, Physiological, and Molecular Aspects of Human Nutrition, lead authors Martha H. Stipanuk and Marie A. Caudill are joined by a team of nutrition experts in providing clear, concise, coverage of advanced nutrition. - 55 expert contributors provide the latest information on all areas of the nutrition sciences. - Nutrition Insight boxes discuss hot topics and take a closer look at basic science and everyday nutrition. - Clinical Correlation boxes show the connection between nutrition-related problems and their effects on normal metabolism. - Food Sources boxes summarize and simplify data from the USDA National Nutrient Database on the amount and types of foods needed to reach the recommended daily allowances for vitamins and minerals. - DRIs Across the Life Cycle boxes highlight the latest data from the Institute of Medicine on dietary reference intakes for vitamins and minerals, including coverage of infants, children, adult males and females, and pregnant and lactating women. - Life Cycle Considerations boxes highlight nutritional processes or concepts applicable to individuals of various ages and in various stages of the life span. - Thinking Critically sections within boxes and at the end of chapters help in applying scientific knowledge to "real-life" situations. - Lists of common abbreviations provide an overview of each chapter's content at a glance. - Comprehensive cross-referencing by chapters and illustrations is used throughout. - Current references and recommended readings connect you to nutrition-related literature and provide additional tools for research. - Coverage of the USDA's MyPlate dietary guide reflects today's new approach to diet and nutrition. - Recommendations outlined in the Dietary Guidelines for Americans 2010 are incorporated throughout the book. - Updated format features more subheadings, tables, and bullets, making it easier to learn and recall key points. - Updates of key chapters and boxes reflect significant changes within the fields of nutrition, biology, molecular biology, and chemistry. - NEW illustrations simplify complex biochemical, physiological, and molecular processes and concepts.

New York Legislative Documents

Author : New York (State). Legislature
Publisher :
ISBN 13 :
Total Pages : 2042 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis New York Legislative Documents by : New York (State). Legislature

Download or read book New York Legislative Documents written by New York (State). Legislature and published by . This book was released on 1924 with total page 2042 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Primer to The Immune Response

Author : Tak W. Mak
Publisher : Academic Press
ISBN 13 : 008056965X
Total Pages : 455 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Primer to The Immune Response by : Tak W. Mak

Download or read book Primer to The Immune Response written by Tak W. Mak and published by Academic Press. This book was released on 2008-04-22 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primer to The Immune Response is an invaluable resource for college students, university undergraduates and students in medicine and other health professions who need a concise but complete and understandable introduction to immunology. This book is written in the same engaging conversational style as the published reference book The Immune Response: Basic and Clinical Principles and conveys the same fascinating appeal of immunology. The authors bring clarity, readability and continuity of voice to an audience that requires only a brief survey of the most fundamental concepts in basic and clinical immunology. Primer to The Immune Response is beautifully illustrated with over 200 superb figures and 36 full-color plates, and further enhanced by the inclusion of 60 tables and 6 Appendices. Included with purchase of the book is website access to a captivating "Immunomovie"? that truly brings the immune response to pathogens to life. This new and unique immunology textbook compactly but elegantly covers both basic and clinical principles. - Over 200 elegant 2-4 color illustrations - 36 full-color plates of basic and clinical items of interest - Take-home message and "Did You Get It? self-test quiz at the end of each chapter - 6 Appendices that provide topic enrichment - 60-minute "Immunomovie"? illustrating the immune response to bacterial, viral and parasitic infections

Comprehensive Toxicology

Author :
Publisher : Elsevier
ISBN 13 : 0081006128
Total Pages : 8639 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Toxicology by :

Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2017-12-01 with total page 8639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts