Methotrexate In Rheumatic Diseases

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Drug-Induced Liver Injury

Author :
Publisher : Academic Press
ISBN 13 : 0128173173
Total Pages : 290 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug-Induced Liver Injury by :

Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series

Skills in Rheumatology

Author : Hani Almoallim
Publisher : Springer Nature
ISBN 13 : 9811583234
Total Pages : 562 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Skills in Rheumatology by : Hani Almoallim

Download or read book Skills in Rheumatology written by Hani Almoallim and published by Springer Nature. This book was released on 2021-01-05 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.

Hepatotoxicity

Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781719520
Total Pages : 850 pages
Book Rating : 4.7/5 (195 download)

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Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman

Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Polymyositis and Dermatomyositis

Author : Marinos C. Dalakas
Publisher : Butterworth-Heinemann
ISBN 13 : 1483163040
Total Pages : 362 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Polymyositis and Dermatomyositis by : Marinos C. Dalakas

Download or read book Polymyositis and Dermatomyositis written by Marinos C. Dalakas and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymyositis and Dermatomyositis provides extensive information regarding Polymyositis and Dermatomyositis (PM/DM), which is described as a heterogeneous disease complex. This book is divided into four sections: Part I (Clinical Features) covers the classification of PM/DM, details of the clinical presentation, and the disease's association with the other connective tissue disorders and malignancies. Part II (Etiology and Mechanisms) covers advances in the immunopathology and viral etiology of PM/DM along with a frequently recognized entity: inclusion body myositis. Part III (Diagnosis and Treatment) covers the histologic, muscle enzyme histochemical, electron microscopic, and resin histology features of PM/DM along with those electromyographic features that could help make a more accurate diagnosis. Part IV (Overview) summarizes the issues that may not have been clear and highlights differing and unsettled views or present available data. This text is directed to clinicians in private practice or in academic institutions concerned with PM/DM patients, including neurologists, rheumatologists, pediatricians, dermatologists, physiatrists, and neuromuscular investigators. This book is intended as well for neuromuscular pathologists who interpret muscle biopsy specimens and electromyographers who perform EMG studies to help determine the clinical diagnosis. Researchers in immunology and immunopathology of neuromuscular diseases will find discussions in this book invaluable.

A Clinician's Pearls & Myths in Rheumatology

Author : John H. Stone
Publisher : Springer Science & Business Media
ISBN 13 : 1848009348
Total Pages : 489 pages
Book Rating : 4.8/5 (48 download)

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Book Synopsis A Clinician's Pearls & Myths in Rheumatology by : John H. Stone

Download or read book A Clinician's Pearls & Myths in Rheumatology written by John H. Stone and published by Springer Science & Business Media. This book was released on 2009-10-03 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Important strides have been made in understanding the pathophysiologic basis of many inflammatory conditions in recent years, but rheumatology remains a discipline in which diagnosis is rooted in the medical history skillfully extracted from the patient, the careful physical examination, and the discriminating use of laboratory tests and imaging. Moreover, selection of the most appropriate therapy for patients with rheumatic diseases also remains heavily reliant upon clinical experience. Medical disciplines such as rheumatology that depend significantly upon clinical wisdom are prone to the development of systems of ‘Pearls’ and ‘Myths,’ related to the diseases they call their own, a ‘Pearl’ being a nugget of truth about the diagnosis or treatment of a particular disease that has been gained by dint of clinical experience and a ‘Myth’ being a commonly held belief that influences the practice of many clinicians – but is false. This book will pool together the clinical wisdom of seasoned, expert rheumatologists who participate in the care of patients with autoimmune diseases, systemic inflammatory disorders, and all other rheumatic conditions.

Early Rheumatoid Arthritis

Author : Paul Emery
Publisher :
ISBN 13 : 9781416027676
Total Pages : 0 pages
Book Rating : 4.0/5 (276 download)

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Book Synopsis Early Rheumatoid Arthritis by : Paul Emery

Download or read book Early Rheumatoid Arthritis written by Paul Emery and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.

Pulmonary Manifestations of Rheumatic Disease

Author : Paul F. Dellaripa
Publisher : Springer
ISBN 13 : 1493907700
Total Pages : 227 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Pulmonary Manifestations of Rheumatic Disease by : Paul F. Dellaripa

Download or read book Pulmonary Manifestations of Rheumatic Disease written by Paul F. Dellaripa and published by Springer. This book was released on 2014-05-23 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: The spectrum of systemic rheumatologic disease (often termed connective tissue disease) is characterized by autoimmune-mediated organ dysfunction, and the lungs are a frequent target. There are numerous pulmonary manifestations associated with connective tissue diseases, and all patients with rheumatologic disease are at risk of developing associated lung disease. Pulmonary Manifestations of Rheumatic Disease covers the comprehensive management of rheumatologic lung disease, which requires a multi-disciplinary approach and is optimized by active engagement by rheumatologists working closely with pulmonologists and other specialists. The book offers a practical reference using a case-based approach for practicing clinicians in the ongoing assessment and understanding of rheumatologic lung disease, and presents the science and pathophysiology underlying rheumatologic lung diseases. The first text of its kind specifically dedicated to describe diverse, commonplace, and challenging aspects of rheumatologic lung diseases, Pulmonary Manifestations of Rheumatic Disease serves as an invaluable tool for the practicing clinician.

Introduction to Basics of Pharmacology and Toxicology

Author : Abialbon Paul
Publisher : Springer Nature
ISBN 13 : 9813360097
Total Pages : 1156 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Introduction to Basics of Pharmacology and Toxicology by : Abialbon Paul

Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Drug Discovery

Author : Robert A. Maxwell
Publisher : Springer Science & Business Media
ISBN 13 : 1461204690
Total Pages : 443 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Drug Discovery by : Robert A. Maxwell

Download or read book Drug Discovery written by Robert A. Maxwell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This treatise had its origins in the authors' strong opinion that the discovery of new drugs, especially of innovative therapeutic agents, really does not happen as a spontaneous sequel to investiga tive research, no matter how penetrating such research may be. Rather, it seemed to us that the discovery of innovative therapeutic agents was a very active process, existing in and of itself, and demanding full attention-it was not simply a passive, dependent by-process of investigative research. And yet, many researchers some close confreres of the authors, others more distant-believed otherwise. We felt that their view reflected unrealistic thinking and that reality probably lay closer to what Beyer" maintained: We are taught to believe that if we can understand a disease it should be easy enough to figure out, say, the molecular configuration of a definitive receptor mechanism somewhere along the line and to design a specific drug . . . . And so we start out to understand the disease but never get around to doing much about therapy. The authors very soon realized that there was essentially no quantitive information available on just where and how innovative therapeutic agents were discovered. There were only anecdotal accounts, and these were able to be selected and presented in ways that could be used to defend any point of view.

Rheumatology and Immunology

Author : Alan S. Cohen
Publisher :
ISBN 13 :
Total Pages : 552 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Rheumatology and Immunology by : Alan S. Cohen

Download or read book Rheumatology and Immunology written by Alan S. Cohen and published by . This book was released on 1986 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comorbidity in Rheumatic Diseases

Author : Yasser El Miedany
Publisher : Springer
ISBN 13 : 3319599631
Total Pages : 439 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Comorbidity in Rheumatic Diseases by : Yasser El Miedany

Download or read book Comorbidity in Rheumatic Diseases written by Yasser El Miedany and published by Springer. This book was released on 2017-08-24 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores comorbidity in patients with rheumatic diseases and details both care and treatment options in standard clinical practice. Patients with rheumatic diseases are clinically complex, and the interplay of their disease activity with associated conditions may lead to increased morbidity and mortality. Recently there have been major advances in the management of rheumatic diseases, however, without addressing the potential comorbid conditions, including cardiovascular disease; pulmonary disease; and depression; outcomes remain poor. With its 19 chapters, covering the management of major rheumatic diseases (e.g. rheumatoid arthritis, systemic lupus erythematosus , and osteoarthritis), potential comorbidities and treatment recommendations, as well as possible interactions between conditions; this book addresses the gap between textbook medicine and day to day patients' care. Authors also discuss the new hot issue of the comorbidity index, comparing the standard tools to the recently developed indices and how they can assist the rheumatologists in determining disease burden, prognosis, and comorbidity probability. This book is an ideal clinical guide and reference that enables rheumatologists, internal medicine physicians, and residents to address the full clinical expression of these rheumatic diseases with views towards prevention or early management of comorbid conditions.

Encyclopedia of Inflammatory Diseases

Author :
Publisher : Birkhäuser
ISBN 13 : 9783764385309
Total Pages : 0 pages
Book Rating : 4.3/5 (853 download)

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Book Synopsis Encyclopedia of Inflammatory Diseases by :

Download or read book Encyclopedia of Inflammatory Diseases written by and published by Birkhäuser. This book was released on 2016-09-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation has become one of the most exciting and rewarding areas of medical research. Recent years have seen a revolution in our understanding of how blood and tissue cells interact and of the intracellular mechanisms controlling their activation. This has revealed the underlying inflammatory pathology of many diseases and provided multiple new targets for anti-inflammatory and immunomodulatory therapy. The Encyclopedia of Inflammatory Diseases will cover the following areas: Inflammatory Processes and Cells Inflammatory Diseases Mediators of Inflammation Pharmacology of Inflammation Since inflammatory diseases and their therapy cover a broad range of scientific and medical fields, the encyclopedia will be co-edited by four international experts, a clinician and three researchers from the disciplines of immunology, biochemistry, and pharmacology, in this way providing students, basic and clinical scientists and practitioners in academia, hospitals and industry with valuable interlinked information. This living project will serve as a reliable and comprehensive data pool for everybody working in inflammation research. Owing to its dynamic nature, it will grow with time and future editions, becoming an indispensible source of information for academia, clinical practitioners and industry.

Papich Handbook of Veterinary Drugs - E-Book

Author : Mark G. Papich
Publisher : Elsevier Health Sciences
ISBN 13 : 0323709583
Total Pages : 1060 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Papich Handbook of Veterinary Drugs - E-Book by : Mark G. Papich

Download or read book Papich Handbook of Veterinary Drugs - E-Book written by Mark G. Papich and published by Elsevier Health Sciences. This book was released on 2020-10-06 with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 in Veterinary Medicine** Papich Handbook of Veterinary Drugs, 5th Edition includes concise entries for more than 550 drugs, with appendices summarizing clinically relevant information at a glance. Nineteen new drug monographs are added to this edition, and over 100 drug monographs have been updated and revised. An Expert Consult website contains more than 150 instructional handouts that may be customized and printed out for your clients. Written by clinical pharmacology expert Mark Papich, this handy reference makes it easy to find the drug data and dosage recommendations you need to treat small and large animals, right when you need it! - Over 550 concise drug monographs are organized alphabetically and cross-referenced by classification, trade, and generic name, providing quick and easy access to key information for each drug including:• Generic and trade names, pronunciation, and functional classification • Pharmacology and mechanism of action • Indications and clinical uses • Precautionary information — adverse reactions and side effects, contraindications and precautions, and drug interactions — all featured in colored boxes for at-a-glance retrieval • Instructions for use • Patient monitoring and laboratory tests • Formulations available • Stability and storage • Dosage information for both small and large animals • Regulatory information - Clinically relevant appendices help you determine appropriate therapeutic regimens and look up safety and legal considerations. - NEW! 19 new drug monographs familiarize you with the latest drugs available for veterinary practice. - UPDATED drug monographs include new information such as changes in doses, interactions, indications, adverse reactions, and contraindications. - NEW! Expert Consult companion website replaces the former website and includes more than 150 customizable client information handouts for commonly prescribed drugs, including information on the prescribed drug and dosage, do's and don'ts, and possible side effects. - NEW! Removal of entries for drugs that have been taken off the market.

Therapy for Severe Psoriasis E-Book

Author : Jashin J. Wu
Publisher : Elsevier Health Sciences
ISBN 13 : 0323447988
Total Pages : 217 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Therapy for Severe Psoriasis E-Book by : Jashin J. Wu

Download or read book Therapy for Severe Psoriasis E-Book written by Jashin J. Wu and published by Elsevier Health Sciences. This book was released on 2016-12-02 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: A brand-new title in the field of dermatology, Therapy for Severe Psoriasis provides the ultimate coverage of the treatment options available for today's most serious cases, including biologics and oral therapies. It features discussions of the newest drug therapies, recent FDA-approved biosimilars, and combination approaches to care, while an overview chapter was designed to aid those new to the field in understanding the nuances of difficult-to-treat subtypes of psoriasis. Comprehensive and focused, Therapy for Severe Psoriasis will be a welcome addition to the library of any dermatologist seeking in-depth information on the challenges of this condition. - Each of the 16 chapters includes either an in-depth focus on a single therapy or an overview of a unique aspect of psoriasis, including: UVB therapy, methotrexate, acitretin, cyclosporine, apremilast, etanercept, infliximab, adalimumab, ustekinumab, secukinumab, and ixekizumab. - Takes an evidence-based approach to hard-to-treat severe psoriasis. - Discusses the newest drug therapies (such as ixekizumab), plus recent FDA-approved biosimilars, a topic unique to this particular psoriasis text. - Presents combination approaches for instances when standard treatments are not successful. - Includes an overview chapter to help beginners understand the nuances of the disorder.

Rheumatoid Arthritis

Author : John J. Cush
Publisher :
ISBN 13 : 1932610286
Total Pages : 368 pages
Book Rating : 4.9/5 (326 download)

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Book Synopsis Rheumatoid Arthritis by : John J. Cush

Download or read book Rheumatoid Arthritis written by John J. Cush and published by . This book was released on 2008-01-01 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizes the importance of early intervention in RA with focus on pharmacologic treatment of RA. Detailed information on the various medications employed in treatment, including corticosteroids, NSAIDs DMARDs, biologic agents, and combination therapy is reviewed, including evidence based data on efficacy, safety, side effects, and monitoring requirements. Clinical evaluation is presented, including lab findings, joint scoring, diagnostic criteria, and radiographic outcomes. Surgical options and the management of advanced RA are disussed.

Encyclopedia of Medical Immunology

Author : Ian R. Mackay
Publisher :
ISBN 13 : 9781461492092
Total Pages : pages
Book Rating : 4.4/5 (92 download)

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Book Synopsis Encyclopedia of Medical Immunology by : Ian R. Mackay

Download or read book Encyclopedia of Medical Immunology written by Ian R. Mackay and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a broad appeal to microbiologists, immunologists, and infectious disease specialists, this four volume encyclopedia covers all autoimmune, tropical, and infectious diseases. Emphasis will also be placed on genetics, physiology, metabolism, pathogenesis and applied microbiology. Under the leadership of some of the most world renowned names in the field, the encyclopedia will bring together an outstanding collection of contributions by top scientists in a variety of fields. Volumes 1-3: Diseases will be divided by the 11 main sections of the body, namely Integumentary, Skeletal, Respiratory, Digestive, Urinary, and Reproductive. For some of the autoimmune disease, more then one system will be involved but the delineation serves to broadly break down the diseases into systems. Volume 4 will cover the vaccines for said diseases and future prospects will be offered by leaders in industry and academia. Volume 4 will also be broken down into all the body systems, as in the other two volumes. For each vaccine, for each disease, and in each system the following will be included: • A list of the vaccines currently available along with a list of the companies that manufacture them • Molecular Immunology of the Vaccine • Type of Immunity involved in protection • Mode of Vaccination for each vaccine; repeated boosters and length of immunological memory • Commercial production of vaccines • Storage of vaccines • Standardization and Control of Vaccines • WHO programs and World-Wide Disease Eradication Programs based upon Vaccines.

Pediatric Rheumatology, an Issue of Rheumatic Disease Clinics

Author : Andreas Reiff
Publisher : Clinics: Internal Medicine
ISBN 13 : 9780323242356
Total Pages : 0 pages
Book Rating : 4.2/5 (423 download)

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Book Synopsis Pediatric Rheumatology, an Issue of Rheumatic Disease Clinics by : Andreas Reiff

Download or read book Pediatric Rheumatology, an Issue of Rheumatic Disease Clinics written by Andreas Reiff and published by Clinics: Internal Medicine. This book was released on 2013-11-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Rheumatic Disease Clinics teaches you the latest developments and best practices in pediatric rheumatology. Guest edited by Andreas Reiff, topics include juvenile arthritis, juvenile spondyloarthritis, inflammatory bowel disease, vasculitis, scleroderma, eye conditions, and more