Metal-Controlled Assembly of Peptide and Protein-based Engineered Biomaterials

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Publisher :
ISBN 13 :
Total Pages : 218 pages
Book Rating : 4.:/5 (945 download)

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Book Synopsis Metal-Controlled Assembly of Peptide and Protein-based Engineered Biomaterials by : Sarah Jane Smith

Download or read book Metal-Controlled Assembly of Peptide and Protein-based Engineered Biomaterials written by Sarah Jane Smith and published by . This book was released on 2016 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein-protein interactions are ubiquitous throughout nature at many length and time scales--from transient interactions between individual proteins for signaling and electron transfer to the self-assembly over large distances of bacterial S-layer protein coats. Extensive research has been undertaken to attempt to mimic, interrogate, interrupt, or design protein-protein interactions, but natural protein-protein interactions often form as a result of many accumulated weak interactions over large, heterogeneous molecular surfaces, making them challenging to design. As a way to overcome these challenges, we have previously introduced methods of synthesizing protein-protein interactions with minimal surface design through the directional and highly controllable coordination of metal ions on protein surfaces. The goal of this thesis work has been to expand the scope and functionality of these metal-directed protein and peptide interactions. First, we show that, like proteins, short peptides can be directed to fold and assemble in biologically relevant ways using coordination chemistry, while incorporating additional metal-based functionality on the peptide backbone. We then extend the scale of protein self-assembly to highly ordered, crystalline protein nanotubes with tunable diameters. Finally, we demonstrate the ability to assemble protein-DNA nanomaterials in a manner that, similar to what is observed in nature, relies on the sum of a number of weak interactions to form highly ordered protein-DNA arrays. Overall, we demonstrate the ability to use metal ions to coordinate interactions on scales as small as single protein-protein interactions to as large as micrometer scale arrays. Here, we have expanded the functionality of these metal-directed protein and peptide interactions. First, we show that peptides can be directed to fold and assemble in biologically relevant ways using coordination chemistry, while incorporating additional metal-based functionality on the peptide backbone. We then extend the scale of assembly to highly ordered, crystalline protein nanotubes with tunable diameters. Finally, we demonstrate the ability to assemble protein-DNA nanomaterials in a manner that, similar to what is observed in nature, relies on the sum of a number of weak interactions to form highly ordered protein-DNA arrays. Overall, we demonstrate the ability to use metal ions to coordinate interactions on scales as small as single protein-protein interactions to as large as micrometer scale arrays.

Peptide Self-Assembly and Engineering

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Publisher : John Wiley & Sons
ISBN 13 : 3527841253
Total Pages : 933 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Peptide Self-Assembly and Engineering by : Xuehai Yan

Download or read book Peptide Self-Assembly and Engineering written by Xuehai Yan and published by John Wiley & Sons. This book was released on 2024-02-09 with total page 933 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptide Self-Assembly and Engineering State-of-the-art research in peptide self-assembly, with coverage of fundamental aspects of how peptides self-assemble and an extensive number of applications Peptide Self-Assembly and Engineering: Fundamentals, Structures, and Applications (2V set) covers the latest progresses in the field of peptide self-assembly and engineering, including the fundamental principles of peptide self-assembly, new theory of nucleation and growth, thermodynamics and kinetics, materials design rules, and precisely controlled structures and unique functions. The broad contents from this book enable readers to obtain a systematical and comprehensive knowledge in the field of peptide self-assembly and engineering. Contributed by the leading scientists and edited by a highly qualified academic and an authority in the field, Peptide Self-Assembly and Engineering includes information on: Emerging areas in peptide assembly, such as immune agents, bioelectronics, energy conversion, flexible sensors, biomimetic catalysis, and more Existing applications in biomedical engineering, nanotechnology, and photoelectronics, including tissue engineering, drug delivery, and biosensing devices History of peptide self-assembly for design of functional materials and peptides’ unique mechanical, optical, electronic, and biological properties Various solvent conditions, such as pH, ionic strength, and polarity, that can affect the structure and stability of peptide assemblies A very comprehensive reference covering the latest progresses in the field of peptide self-assembly and engineering, Peptide Self-Assembly and Engineering is an essential resource for all scientists performing research intersecting with the subject, including biochemists, biotechnologists, pharmaceutical chemists, protein chemists, materials scientists, and medicinal chemists.

Peptide-Based Materials

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Publisher : Springer Science & Business Media
ISBN 13 : 3642271383
Total Pages : 184 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Peptide-Based Materials by : Timothy Deming

Download or read book Peptide-Based Materials written by Timothy Deming and published by Springer Science & Business Media. This book was released on 2012-01-13 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Polypeptides by Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides, by Jianjun Cheng and Timothy J. Deming.- Peptide Synthesis and Self-Assembly, by S. Maude, L. R. Tai, R. P. W. Davies, B. Liu, S. A. Harris, P. J. Kocienski and A. Aggeli.- Elastomeric Polypeptides, by Mark B. van Eldijk, Christopher L. McGann, Kristi L. Kiick andJan C. M. van Hest.- Self-Assembled Polypeptide and Polypeptide Hybrid Vesicles: From Synthesis to Application, by Uh-Joo Choe, Victor Z. Sun, James-Kevin Y. Tan and Daniel T. Kamei.- Peptide-Based and Polypeptide-Based Hydrogels for Drug Delivery and Tissue Engineering, by Aysegul Altunbas and Darrin J. Pochan.-

Peptide-based Biomaterials

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Publisher : Royal Society of Chemistry
ISBN 13 : 1839161159
Total Pages : 413 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Peptide-based Biomaterials by : Mustafa O. Guler

Download or read book Peptide-based Biomaterials written by Mustafa O. Guler and published by Royal Society of Chemistry. This book was released on 2020-11-18 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research and new tools in biomaterials development by using peptides are currently growing, as more functional and versatile building blocks are used to design a host of functional biomaterials via chemical modifications for health care applications. It is a field that is attracting researchers from across soft matter science, molecular engineering and biomaterials science. Covering the fundamental concepts of self-assembly, design and synthesis of peptides, this book will provide a solid introduction to the field for those interested in developing functional biomaterials by using peptide derivatives. The bioactive nature of the peptides and their physical properties are discussed in various applications in biomedicine. This book will help researchers and students working in biomaterials and biomedicine fields and help their understanding of modulating biological processes for disease diagnosis and treatments.

Peptide Materials

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Publisher : John Wiley & Sons
ISBN 13 : 1118592417
Total Pages : 479 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Peptide Materials by : Carlos Aleman

Download or read book Peptide Materials written by Carlos Aleman and published by John Wiley & Sons. This book was released on 2013-03-29 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides are the building blocks of the natural world; with varied sequences and structures, they enrich materials producing more complex shapes, scaffolds and chemical properties with tailorable functionality. Essentially based on self-assembly and self-organization and mimicking the strategies that occur in Nature, peptide materials have been developed to accomplish certain functions such as the creation of specific secondary structures (a- or 310-helices, b-turns, b-sheets, coiled coils) or biocompatible surfaces with predetermined properties. They also play a key role in the generation of hybrid materials e.g. as peptide-inorganic biomineralized systems and peptide/polymer conjugates, producing smart materials for imaging, bioelectronics, biosensing and molecular recognition applications. Organized into four sections, the book covers the fundamentals of peptide materials, peptide nanostructures, peptide conjugates and hybrid nanomaterials, and applications with chapters including: Properties of peptide scaffolds in solution and on solid substrates Nanostructures, peptide assembly, and peptide nanostructure design Soft spherical structures obtained from amphiphilic peptides and peptide-polymer hybrids Functionalization of carbon nanotubes with peptides Adsorption of peptides on metal and oxide surfaces Peptide applications including tissue engineering, molecular switches, peptide drugs and drug delivery Peptide Materials: From Nanostructures to Applications gives a truly interdisciplinary review, and should appeal to graduate students and researchers in the fields of materials science, nanotechnology, biomedicine and engineering as well as researchers in biomaterials and bio-inspired smart materials.

De Novo Peptide Design

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Publisher : Academic Press
ISBN 13 : 0323985432
Total Pages : 297 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis De Novo Peptide Design by : Vibin Ramakrishnan

Download or read book De Novo Peptide Design written by Vibin Ramakrishnan and published by Academic Press. This book was released on 2022-09-17 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: De novo Peptide Design: Principles and Applications presents the latest developments in the fields of therapeutic peptides and bio-nanotechnology. The title focuses on the design of peptides, particularly how peptides may be tailored to specific functions. It includes computational and experimental protocols to assist in the design of peptides. Sections cover the basics of protein and peptide structure, modeling and simulation, solid phase peptide synthesis, peptide-based antibiotics, drug delivery, peptide nanomaterials, aromatic interactions directing nano-assembly, protein/peptide aggregation, therapeutic interventions against protein/peptide aggregation diseases, peptide based hydrogels, computational tools and algorithms for peptide design, and experimental protocols in peptide chemistry. In addition, the book covers key aspects in peptide design, providing a solution for researchers working within the 'peptidic universe' to create new therapeutic agents. Gives comprehensive coverage, including peptide design, modeling, synthesis and applications Presents emerging topics in the design of peptide-based therapeutics Details the latest developments in the fields of therapeutic peptides and bio-nanotechnology Considers peptide design and the tailoring of peptides to specific functions Offers computational tools and algorithms for peptide design and experimental protocols for peptide chemistry

Peptides and Peptide-based Biomaterials and their Biomedical Applications

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Publisher : Springer
ISBN 13 : 3319660950
Total Pages : 309 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Peptides and Peptide-based Biomaterials and their Biomedical Applications by : Anwar Sunna

Download or read book Peptides and Peptide-based Biomaterials and their Biomedical Applications written by Anwar Sunna and published by Springer. This book was released on 2017-10-26 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as β-sheet fibril-forming peptides and α-helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.

Self-assembling Biomaterials

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Publisher : Woodhead Publishing
ISBN 13 : 0081020120
Total Pages : 614 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Self-assembling Biomaterials by : Helena S. Azevedo

Download or read book Self-assembling Biomaterials written by Helena S. Azevedo and published by Woodhead Publishing. This book was released on 2018-04-17 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Self-assembling biomaterials: molecular design, characterization and application in biology and medicine provides a comprehensive coverage on an emerging area of biomaterials science, spanning from conceptual designs to advanced characterization tools and applications of self-assembling biomaterials, and compiling the recent developments in the field. Molecular self-assembly, the autonomous organization of molecules, is ubiquitous in living organisms and intrinsic to biological structures and function. Not surprisingly, the exciting field of engineering artificial self-assembling biomaterials often finds inspiration in Biology. More important, materials that self-assemble speak the language of life and can be designed to seamlessly integrate with the biological environment, offering unique engineering opportunities in bionanotechnology. The book is divided in five parts, comprising design of molecular building blocks for self-assembly; exclusive features of self-assembling biomaterials; specific methods and techniques to predict, investigate and characterize self-assembly and formed assemblies; different approaches for controlling self-assembly across multiple length scales and the nano/micro/macroscopic properties of biomaterials; diverse range of applications in biomedicine, including drug delivery, theranostics, cell culture and tissue regeneration. Written by researchers working in self-assembling biomaterials, it addresses a specific need within the Biomaterials scientific community. Explores both theoretical and practical aspects of self-assembly in biomaterials Includes a dedicated section on characterization techniques, specific for self-assembling biomaterials Examines the use of dynamic self-assembling biomaterials

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair

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Publisher : Woodhead Publishing
ISBN 13 : 008100852X
Total Pages : 392 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair by : Mario Barbosa

Download or read book Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair written by Mario Barbosa and published by Woodhead Publishing. This book was released on 2017-09-25 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration Explores protein and peptides from the fundamentals, to processing and applications Written by an international group of leading biomaterials researchers

Design of Metal-Controlled Protein-Protein Interactions

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Publisher :
ISBN 13 :
Total Pages : 135 pages
Book Rating : 4.:/5 (11 download)

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Book Synopsis Design of Metal-Controlled Protein-Protein Interactions by : Brian M. Maniaci

Download or read book Design of Metal-Controlled Protein-Protein Interactions written by Brian M. Maniaci and published by . This book was released on 2019 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of protein design strives to engineer new molecules that interact in a specific, controlled manner to form novel functional complexes. Engineered proteins that generate specific complexes upon the addition of an exogenous agent, such as metal ions, will likely be integral elements of these efforts. Molecular control over protein assembly and disassembly is possible through the introduction of novel metal-binding sites at precise locations in protein complexes. These methods have primarily generated metal-mediated and metal-controlled homodimers. The overall goals of my dissertation projects were to increase our understanding of metal-mediated associations and improve the utility of metal-controlled dimerization systems. As a model system, we used the [beta]1 domain of Protein G (G[beta]1) as a scaffold to build novel dimer complexes. A published report from a different research group described the generation of a G[beta]1 variant that forms a constitutive, symmetric homodimer. This small, well-characterized dimer was an excellent starting model for the design of metal-controlled dimers as considerable biophysical analysis was performed on this variant, and the high resolution three-dimensional structure was solved with X-ray crystallography. We used structure-based rational design to engineer histidine residues at the dimeric interface, which ultimately resulted in high-affinity, metal-controlled protein-protein interactions. Almost all of our design attempts, which contained various interfacial modifications, were shown to form metal-controlled homodimers that bind with moderate to extremely high affinity. In addition to the successful design of high-affinity symmetric homodimers, we were also interested in generating novel heterodimers that also bind with relative high-affinity. To achieve this we reengineered one of the metal binding sites of a metal-controlled homodimer with oppositely charged side-chains to generate intermolecular protein salt-bridges between an arginine residue on one monomer and two glutamic acid residues on the other. The crystal structures revealed both the designed salt bridges and tetrahedral zinc coordination site. We also demonstrated that binding of the heterodimer complex, which contains the designed salt bridges, was disrupted upon addition of increasing concentrations of sodium chloride. The novel, high-affinity metal-controlled homo- and hetero-dimer proteins could potentially be used as highly effective building blocks for novel biomaterials.

Protein Self-Assembly

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Publisher : Humana
ISBN 13 : 9781493996803
Total Pages : 266 pages
Book Rating : 4.9/5 (968 download)

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Book Synopsis Protein Self-Assembly by : Jennifer J. McManus

Download or read book Protein Self-Assembly written by Jennifer J. McManus and published by Humana. This book was released on 2020-08-08 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.

Peptide And Protein Engineering For Biotechnological And Therapeutic Applications

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Publisher : World Scientific
ISBN 13 : 9811261679
Total Pages : 520 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Peptide And Protein Engineering For Biotechnological And Therapeutic Applications by : Pierre Rousselot-pailley

Download or read book Peptide And Protein Engineering For Biotechnological And Therapeutic Applications written by Pierre Rousselot-pailley and published by World Scientific. This book was released on 2023-01-06 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides and proteins are crucial biomolecules in life. The manifold functions they carry out range from molecular recognition and signaling to catalysis and immune response. However, the native systems are limited to a reduced toolbox of chemical functionalities as well as tridimensional structures. Widening these toolboxes could pave the way to engineer peptides and proteins with enhanced properties compared to their native counterparts and/or with structures and functions unprecedented in Nature. Advances in the chemical and biological synthesis of peptides and proteins, in computational tools, in molecular biology and in high-throughput screening methods are making this realm possible.This book aims to give an overview of the last developments in the field of peptide and protein engineering. It comprises a collection of chapters that span from the production of simple non-proteinogenic building blocks and peptidic scaffolds of different sizes and structures to more complex systems including peptide-based nanomaterials, enzymes and artificial metalloenzymes. Different strategies are described where chemical and biological tools have been developed and combined to attain the desired properties and sought functionalities.The diverse systems described in this book highlight the progress in this important field and represent the starting points for the development of functional biomolecules, biomaterials and hybrid systems capable of addressing key societal challenges of our times in relevant areas such health, environment and energy.

Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids

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Publisher : CRC Press
ISBN 13 : 1135487847
Total Pages : 911 pages
Book Rating : 4.1/5 (354 download)

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Book Synopsis Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids by : Ram I. Mahato

Download or read book Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids written by Ram I. Mahato and published by CRC Press. This book was released on 2004-12-28 with total page 911 pages. Available in PDF, EPUB and Kindle. Book excerpt: Newcomers to the field of biopharmaceuticals require an understanding of the basic principles and underlying methodology involved in developing protein- and nucleic acid-based therapies for genetic and acquired diseases. Introducing the principles of polymer science and chemistry, this book delineates the basic biology required for understanding how biomaterials can be used as drug-deliver vehicles. No book to date combines a discussion of high-tech biomaterials-based delivery of protein and nucleic acid drugs with the pharmaceutical or biocompatibility aspects. Leading experts from around the world discuss the physiochemical parameters used for design, development, and evaluation of biotechnological dosage forms for delivery of proteins, peptides, oligonucleotides, and genes. The book includes coverage biological barriers to extravasation and cellular uptake of proteins and nucleic acids.

Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine

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Publisher : Academic Press
ISBN 13 : 032390985X
Total Pages : 316 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine by : Alok Pandya

Download or read book Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine written by Alok Pandya and published by Academic Press. This book was released on 2022-08-04 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine discusses recent advances in science and technology using nanoscale units that show the novel concept of combining nanotechnology with various research disciplines within both the biomedical and medicine fields. Self-assembly of molecules, macromolecules, and polymers is a fascinating strategy for the construction of various desired nanofabrication in chemistry, biology, and medicine for advanced applications. It has a number of advantages: (1) It is involving atomic-level modification of molecular structure using bond formation advanced techniques of synthetic chemistry. (2) It draws from the enormous wealth of examples in biology for the development of complex, functional structures. (3) It can incorporate biological structures directly as components in the final systems. (4) It requires that the target self-assembled structures be thermodynamically most stable with relatively defect-free and self-healing. In this book, we cover the various emerging self-assembled nanostructured objects including molecular machines, nano-cars molecular rotors, nanoparticles, nanosheets, nanotubes, nanowires, nano-flakes, nano-cubes, nano-disks, nanorings, DNA origami, transmembrane channels, and vesicles. These self-assembled materials are used for sensing, drug delivery, molecular recognition, tissue engineering energy generation, and molecular tuning. Provides a basic understanding of how to design, and implement various self-assembled nanobiomaterials Covers principles implemented in the constructions of novel nanostructured materials Offers many applications of self-assemblies in fluorescent biological labels, drug and gene delivery, bio-detection of pathogens, detection of proteins, probing of DNA structure, tissue engineering, and many more

Self-Assembled Peptide Nanostructures

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Publisher : CRC Press
ISBN 13 : 9814364479
Total Pages : 318 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Self-Assembled Peptide Nanostructures by : Jaime Castillo

Download or read book Self-Assembled Peptide Nanostructures written by Jaime Castillo and published by CRC Press. This book was released on 2012-11-21 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: The self-organization of bionanostructures into well-defined functional machineries found in nature has been a priceless source of ideas for researchers. The molecules of life, proteins, DNA, RNA, etc., as well as the structures and forms that these molecules assume serve as rich sources of ideas for scientists or engineers who are interested in de

Nanotechnology for Bioengineers

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Publisher : Springer Nature
ISBN 13 : 3031016688
Total Pages : 95 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Nanotechnology for Bioengineers by : Wujie Zhang

Download or read book Nanotechnology for Bioengineers written by Wujie Zhang and published by Springer Nature. This book was released on 2022-05-31 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is an interdisciplinary field that is rapidly evolving and expanding. Significant advancements have been made in nanotechnology-related disciplines in the past few decades and continued growth and progression in the field are anticipated. Moreover, nanotechnology, omnipresent in innovation, has been applied to resolve critical challenges in nearly every field, especially those related to biological technologies and processes. This book, used as either a textbook for a short course or a reference book, provides state-of-the-art analysis of essential topics in nanotechnology for bioengineers studying and working in biotechnology, chemical/biochemical, pharmaceutical, biomedical, and other related fields. The book topics range from introduction to nanotechnology and nanofabrication to applications of nanotechnology in various biological fields. This book not only intends to introduce bioengineers to the amazing world of nanotechnology, but also inspires them to use nanotechnology to address some of the world's biggest challenges.

Self-assembling Biomaterials

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Publisher : Woodhead Publishing
ISBN 13 : 9780081020159
Total Pages : 0 pages
Book Rating : 4.0/5 (21 download)

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Book Synopsis Self-assembling Biomaterials by : Helena S. Azevedo

Download or read book Self-assembling Biomaterials written by Helena S. Azevedo and published by Woodhead Publishing. This book was released on 2018-04-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Self-assembling biomaterials: molecular design, characterization and application in biology and medicine provides a comprehensive coverage on an emerging area of biomaterials science, spanning from conceptual designs to advanced characterization tools and applications of self-assembling biomaterials, and compiling the recent developments in the field. Molecular self-assembly, the autonomous organization of molecules, is ubiquitous in living organisms and intrinsic to biological structures and function. Not surprisingly, the exciting field of engineering artificial self-assembling biomaterials often finds inspiration in Biology. More important, materials that self-assemble speak the language of life and can be designed to seamlessly integrate with the biological environment, offering unique engineering opportunities in bionanotechnology. The book is divided in five parts, comprising design of molecular building blocks for self-assembly; exclusive features of self-assembling biomaterials; specific methods and techniques to predict, investigate and characterize self-assembly and formed assemblies; different approaches for controlling self-assembly across multiple length scales and the nano/micro/macroscopic properties of biomaterials; diverse range of applications in biomedicine, including drug delivery, theranostics, cell culture and tissue regeneration. Written by researchers working in self-assembling biomaterials, it addresses a specific need within the Biomaterials scientific community.