Mechanisms and Therapy of Liver Cancer

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Publisher : Academic Press
ISBN 13 : 0128240318
Total Pages : 404 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Mechanisms and Therapy of Liver Cancer by :

Download or read book Mechanisms and Therapy of Liver Cancer written by and published by Academic Press. This book was released on 2021-02-10 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms and Therapy of Liver Cancer, Volume 149, presents the latest information on the incidence and mortality of liver cancer research and how it has gained significant momentum because of its direct causative association with obesity-induced fatty liver disease. The literature on liver cancer is moving fast with exciting, novel findings, providing new insights reflected in the following updated chapters: Introduction and molecular classification of HCC, Signaling Pathways in Liver Cancer, HCV and HCC, NASH and HCC, Microbiome and Metabolic Abnormalities in HCC, Systemic Therapy of Liver Cancer, Immunotherapy of Liver Cancer, and Desmoplastic Tumor Microenvironment and Intrahepatic Cholangiocarcinoma Progression: Mechanisms and Therapeutic Implications. Provides the latest information on liver cancer research Offers outstanding and original reviews on a range of topics focused on liver cancer Serves as an indispensable reference on liver cancer for researchers and students alike

Hepatocellular Carcinoma

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Author :
Publisher : Springer
ISBN 13 : 3319094149
Total Pages : 74 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Hepatocellular Carcinoma by : Rajagopal N. Aravalli

Download or read book Hepatocellular Carcinoma written by Rajagopal N. Aravalli and published by Springer. This book was released on 2014-09-15 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides up-to-date information on the development and progression of hepatocellular carcinoma (HCC) with a review of the cellular and molecular mechanisms involved in the disease process. Recent research in HCC has led to significant progress in our understanding of the cellular processes and molecular mechanisms that occur during multi-stage events that lead to hepatocarcinogenesis. The emergence of micro RNAs and molecular targeted therapies have added a new dimension in our efforts to combat this deadly disease, Chapters include discussion and evaluation of current intervention strategies and therapeutic options and a focus on the novel approaches that are being pursued, such as micro-RNA based therapies and personalized medicine to treat liver cancer. This book will be of interest to basic and clinical researchers, as well as to drug developers.

Liver Cancers

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Publisher : Springer
ISBN 13 : 3319922165
Total Pages : 312 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Liver Cancers by : Tim Cross

Download or read book Liver Cancers written by Tim Cross and published by Springer. This book was released on 2018-12-12 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in detail the primary liver cancers of hepatocellular carcinoma and cholangiocarcinoma examining the pathogenesis of disease along with diagnosis and current management options together with exploration of future treatment strategies and areas of controversy. Furthermore, the book highlights management of the common secondary malignancies and touches on benign liver tumours and how to best manage these. Written in a clear and didactic style, this volume includes summaries of the key learning points and questions so that the reader can gauge their knowledge and understanding. This book is aimed to broaden the knowledge base of primary care physicians, general physicians along with specialists in hepatology, oncology and hepato-biliary surgery

Liver Cancer

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789844487
Total Pages : 188 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Liver Cancer by : Ahmed Lasfar

Download or read book Liver Cancer written by Ahmed Lasfar and published by BoD – Books on Demand. This book was released on 2018-11-21 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers remarkable coverage of liver cancer from etiology to prevention and treatment. It provides an updated and new vision of this major cancer that continues to affect hundreds of thousands of people and remains one of the leading causes of cancer deaths around the world. To ensure the high quality of this book, important insights are included and rigorously discussed in a simple and authentic way. The book includes detailed and updated descriptions of the main causes of liver cancer and also the prevention and treatment of this disease. This book is a relevant source of knowledge, very useful for researchers, medical doctors, medical residents, students, healthcare providers, public health decision makers, and all individuals interested in the prevention of this disease.

Novel Therapeutic Approaches for Biliary Tract Cancer and Hepatocellular Carcinoma

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Publisher : Frontiers Media SA
ISBN 13 : 2832539661
Total Pages : 138 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Novel Therapeutic Approaches for Biliary Tract Cancer and Hepatocellular Carcinoma by : Daniel Neureiter

Download or read book Novel Therapeutic Approaches for Biliary Tract Cancer and Hepatocellular Carcinoma written by Daniel Neureiter and published by Frontiers Media SA. This book was released on 2023-11-24 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatobiliary cancers, encompassing biliary tract cancer (BTC) and hepatocellular carcinoma (HCC) are highly lethal. Biliary tract cancer is a deadly disease with a very low five-year survival rate. BTC is assumed to be the fifth most common gastrointestinal malignancy and can be categorized into extrahepatic cholangiocarcinoma (EHC), intrahepatic cholangiocarcinoma (IHC) and gallbladder cancer (GBC), based on the anatomic location. Patients suffering from BTC can be currently treated with radiation therapy, palliative or with a combination of two chemotherapeutics, cisplatin and gemcitabine. Hepatocellular carcinoma is the most prevalent form of liver cancers and was responsible for over 830,000 deaths related to cancer worldwide in 2020. HCC is therefore the second most leading cause of cancer deaths globally. Current treatment options encompass targeted therapy with sorafenib, immunotherapy and post-surgery adjuvant chemotherapy. Factors that might contribute to these dismal outcomes are diagnosis at an already late stage, due to unspecific symptoms, limited therapeutic options, lack of targets and understanding of molecular processes during carcinogenesis as well as resistance to current chemotherapy/treatment. Therefore, these current issues need to be further addressed and solutions and alternative approaches must be provided in order to detect these illnesses at an early stage, prolong the survival time of patients suffering from HCC and BTC and overcome general resistance to available treatment options. The aim of this research topic is to provide an overview about mechanisms of therapy resistance, the identification of therapeutic relevant targets and finally, innovative and alternative approaches for treating BTC and HCC successfully.

Liver Regeneration and Carcinogenesis

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Author :
Publisher : Elsevier
ISBN 13 : 0080535542
Total Pages : 427 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Liver Regeneration and Carcinogenesis by : Bozzano G Luisa

Download or read book Liver Regeneration and Carcinogenesis written by Bozzano G Luisa and published by Elsevier. This book was released on 1995-09-27 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level

Molecular Aspects of Hepatocellular Carcinoma

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Publisher : Bentham Science Publishers
ISBN 13 : 1608050726
Total Pages : 209 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Molecular Aspects of Hepatocellular Carcinoma by : Liang Qiao

Download or read book Molecular Aspects of Hepatocellular Carcinoma written by Liang Qiao and published by Bentham Science Publishers. This book was released on 2012 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic options for late-stage liver cancer are very limited and the prognosis is often poor. A better understanding of the molecular mechanisms involved in the initiation, progression, and metastasis of hepatocellular carcinoma is critical for developing more rational diagnostic and therapeutic approaches. This e-book covers current developments on clinically relevant research on the molecular biology of hepatocellular carcinoma. This e-book should be a valuable reference for professional gastroenterologists, hepatologists and oncologists as well as medical students and researchers.

Dx/Rx: Liver Cancer

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Publisher : Jones & Bartlett Publishers
ISBN 13 : 1449646867
Total Pages : 167 pages
Book Rating : 4.4/5 (496 download)

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Book Synopsis Dx/Rx: Liver Cancer by : Ghassan K. Abou-Alfa

Download or read book Dx/Rx: Liver Cancer written by Ghassan K. Abou-Alfa and published by Jones & Bartlett Publishers. This book was released on 2012-12-23 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dx/Rx: Liver Cancer is a quick and practical reference guide containing all aspects of the diagnosis and therapy of hepatocellular carcinoma (HCC), prognostic and staging systems, clinical management, molecular biology, current controversies, and future insights. Organized into a condensed, bulleted format, this concise reference offers precise and up-to-date information on the epidemiology, classification, diagnosis, treatment, and risk factors for cancers of the liver. Presented in a handy, easy-to-read format, Dx/Rx: Liver Cancer is a must-have resource for oncologists, internists, primary care physicians, and other health care professionals on the ward or in the clinic.

Clinical Dilemmas in Primary Liver Cancer

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Publisher : John Wiley & Sons
ISBN 13 : 0470657979
Total Pages : 241 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Clinical Dilemmas in Primary Liver Cancer by : Roger Williams

Download or read book Clinical Dilemmas in Primary Liver Cancer written by Roger Williams and published by John Wiley & Sons. This book was released on 2011-12-27 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Dilemmas in Liver Cancer follows the successful format of the other books in the Clinical Dilemmas series, with each chapter focused on a specific dilemma, or issue facing doctors in their day-to-day job, and providing them with practical clinical information and help to better assessment and treat their patients – in this case patients suffering from liver cancer, the third commonest cancer in terms of mortality worldwide. Chapters feature up-to-date information on the basic mechanisms, epidemiological risk factors, screening and surveillance strategies, diagnosis and treatment. It is an extremely practical and clinically-orientated book, and as most patients around the world present with advanced disease, a main focus is on the most recent advances allowing early diagnosis and use of locoregional and systemic therapy, surgery, transplantation and combination therapies. Each chapter is authored by an international expert in the relevant area.

Morris Hepatomas

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Publisher : Springer Science & Business Media
ISBN 13 : 1461588529
Total Pages : 773 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Morris Hepatomas by : Harold Morris

Download or read book Morris Hepatomas written by Harold Morris and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1960, Dr. Van R. Potter and Dr. Henry Pitot (at McCardle Laboratory in Madison, Wisconsin), Dr. Tetsuo Ono (then at McCardle Laboratory and now at the Japanese Foundation for Cancer Research in Tokyo, Japan) and Dr. Harold P. Morris (then at the National Cancer Institute and now at Howard University, Washington, D. C. ) decided that an experimental cancer model would be an invaluable tool to examine neoplastic changes in cells. Since they were study ing the various highly specific metabolic processes which are unique to liver tissues, they determined that a transplantable liver cancer model would be the ideal system to work with. This system would provide for comparison of normal liver tissue of the non-tumor bear ing animal, the tumor bearing animal's (host) liver and the liver cancer. Dr. Morris undertook a series of rat studies employing several chemicals known to cause liver cancer. Soon the first Morris hepatomas (#3683, 3924A, 5123) were being studied by several labs. During the next 18 years, Dr. Morris developed and transplanted numerous strains of hepatomas of which no two were identical. These tumors ranged from the very slowly-growing, highly differentiated cancer tissues, e. g. , 96l8A which is a diploid tumor containing gly cogen and a "nearly normal" complement of enzymes, to a large group of rapidly-growing, poorly differentiated cancer tissues, e. g.

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 2

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Publisher : Academic Press
ISBN 13 : 0323993656
Total Pages : 399 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 2 by : Ganji Purnachandra Nagaraju

Download or read book Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 2 written by Ganji Purnachandra Nagaraju and published by Academic Press. This book was released on 2022-04-02 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume Two: Diagnosis, Therapeutic Targets and Molecular Mechanisms for Hepatocellular Carcinoma Progression provides comprehensive information about ongoing research and clinical data surrounding liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. The volume discusses topics such as computational approaches for identification of biomarkers, enzymes and pathways of HCC, circulating and epigenetic biomarkers, drug resistance, metabolic pathways, and small molecule-target therapies. In addition, it discusses immunotherapies, immune check point inhibitors and nanotechnology-based therapies. This book is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer to apply in their research work or clinical setting. Provides detailed information on traditional and novel diagnostic tools for hepatocellular carcinoma Discusses promising targeted therapies, both available and in development, explaining the best option to use for specific cases Brings recent findings in immunotherapies, immune checkpoint inhibitors and nanotechnology-based therapeutic approaches for treatment of HCC

Mechanisms of Chronic Liver Diseases: Identifying New Therapeutic Targets

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Publisher : Frontiers Media SA
ISBN 13 : 2889741567
Total Pages : 279 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Mechanisms of Chronic Liver Diseases: Identifying New Therapeutic Targets by : Gianfranco Danilo Alpini

Download or read book Mechanisms of Chronic Liver Diseases: Identifying New Therapeutic Targets written by Gianfranco Danilo Alpini and published by Frontiers Media SA. This book was released on 2022-01-25 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Liver Cancer

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Author :
Publisher : Nova Biomedical Books
ISBN 13 : 9781612091150
Total Pages : 0 pages
Book Rating : 4.0/5 (911 download)

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Book Synopsis Liver Cancer by : Benjamin J. Valverde

Download or read book Liver Cancer written by Benjamin J. Valverde and published by Nova Biomedical Books. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primary liver cancer, mainly hepatocellular carcinoma (HCC), is the third leading cause of cancer-related deaths world-wide. The incidence is increasing world-wide and the overall survival of patients with HCC is grim because most patients are diagnosed late, when curative treatment is not possible. This book presents topical research in the study of liver cancer, including plant polyphenols for the prevention of HCC and therapy of liver cancer; cytotoxic effects of reservatrol against liver cancer; the molecular mechanisms of HCC and the identification of prognostic markers and health-related quality of life for patients with liver cancer.

Mechanisms of HBx Mediated Liver Cancer: Multiple Pathways and Opportunities

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Publisher :
ISBN 13 : 9789535100232
Total Pages : pages
Book Rating : 4.1/5 (2 download)

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Book Synopsis Mechanisms of HBx Mediated Liver Cancer: Multiple Pathways and Opportunities by : Mark A. Feitelson

Download or read book Mechanisms of HBx Mediated Liver Cancer: Multiple Pathways and Opportunities written by Mark A. Feitelson and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hepatocellular Carcinoma

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Publisher : Springer
ISBN 13 : 3319342142
Total Pages : 594 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Hepatocellular Carcinoma by : Brian I. Carr

Download or read book Hepatocellular Carcinoma written by Brian I. Carr and published by Springer. This book was released on 2016-08-26 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: • Hepatocellular carcinoma (HCC) used to be regarded as a rare disease. However, the increasing numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in most large medical centers means that it is no longer an uncommon disease for gastroenterologists or oncologists to encounter and its incidence and epidemiology are changing. During this exciting time in the field of HCC basic science and clinical management, many changes are simultaneously occurring at multiple levels of our understanding and management of the disease. Suddenly, there are several new choices of therapy to offer patients. Hepatocellular Carcinoma, 3rd edition addresses this fast-changing disease and gives the reader a clearer understanding of the many mechanisms involved in carcinogenesis of the liver. This comprehensive and detailed review of how to diagnose and treat hepatocellular carcinoma is written by international leaders in the field, covering both clinical treatment choices and the basic science underlying HCC development. Updated and enhanced from the last edition in 2009, Hepatocellular Carcinoma, 3rd edition features 12 new chapters including discussion of molecular markers, molecular hepatocarcinogenesis, microenvironment, heterogeneity, the new and exciting contributions of immunotherapy, and updates on the major effective hepatitis therapies that will transform HCC incidence and perhaps also the therapy. This cutting-edge text is a vital resource and must-have for today’s hepatologists and medical and surgical oncologists. "This is a well written text and should be a good reference book for those who see patients with HCC.." - Practical Gastroenterology "...a useful tool for both physicians and surgeons with a specific interest in the management of patients with HCC." - Digestive and Liver Disease

Advances in Cancer Research

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Publisher : Academic Press
ISBN 13 : 9780128151235
Total Pages : 0 pages
Book Rating : 4.1/5 (512 download)

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Book Synopsis Advances in Cancer Research by :

Download or read book Advances in Cancer Research written by and published by Academic Press. This book was released on 2018-01-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research, Volume 137, the latest release in this ongoing, well-regarded serial provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, with this volume covering unconventional approaches to modulating the immunogenicity of tumor cells, tumor dormancy and immunoediting, the emerging role of anti-apoptotic Bcl-2 family proteins in chemoresistance, Beclin-1 and autophagy, MDA-7/IL-24, and nanotechnology and medicine.

100 Questions and Answers about Liver Cancer

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Author :
Publisher : Jones & Bartlett Publishers
ISBN 13 : 1449622895
Total Pages : 137 pages
Book Rating : 4.4/5 (496 download)

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Book Synopsis 100 Questions and Answers about Liver Cancer by : Ghassan K. Abou-Alfa

Download or read book 100 Questions and Answers about Liver Cancer written by Ghassan K. Abou-Alfa and published by Jones & Bartlett Publishers. This book was released on 2011-12-15 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: 100 Questions & Answers About Liver Cancer is a quick and practical reference guide containing all aspects of the diagnosis and therapy of hepatocellular carcinoma (HCC), prognostic and staging systems, clinical management, molecular biology, current controversies, and future insights. Organized into a condensed, bulleted format, this concise reference offers precise and up-to-date information on the epidemiology, classification, diagnosis, treatment, and risk factors for cancers of the liver.