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Mechanics And Energetics Of The Myocardium
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Author :Christian J.F. Holubarsch Publisher :Springer Science & Business Media ISBN 13 :1461508797 Total Pages :219 pages Book Rating :4.4/5 (615 download)
Book Synopsis Mechanics and Energetics of the Myocardium by : Christian J.F. Holubarsch
Download or read book Mechanics and Energetics of the Myocardium written by Christian J.F. Holubarsch and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: During several decades of this century, the classical physiological studies on the cardiovascular system have greatly improved our knowledge on the function of this system under normal and pathological conditions. This knowledge was the basis of the breakthrough for diagnostic techniques like the Swan-Ganz catheter, coronary arteriography, left and right heart biopsies, and invasive measurements of contractility, as well as therapeutic tools including aortocoronary bypass surgery, percutanous transluminal coronary angioplasty, and a broad field of pharmacological interventions for the whole spectrum of cardiovascular diseases, especially chronic heart failure. It was during the last decade that the scientific world focused on the evolution of molecular biology of the cardiovascular system so that cardiovascular physiology seemed to become less important. Regarding the myocardium, molecular alterations of important functional proteins (phenotype changes), as well as signal transduction pathways of contractility and cardiac growth have been elucidated. The functional importance of a number of genes has undoubtedly been proven with the help of transgenic animals. Mechanics and Energetics of the Myocardium provides an overview for those researchers and practioners interested in the broad field of molecular biology and physiology of the cardiovascular system.
Book Synopsis Skinned Fibres in Mechanics and Energetics of the Myocardium by : Maximilian Philipp Schröder
Download or read book Skinned Fibres in Mechanics and Energetics of the Myocardium written by Maximilian Philipp Schröder and published by . This book was released on 2000 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regional Mechanics and Energetics of Stunned Myocardium in Vivo by : Serge Alexander Ivo Petrus Trines
Download or read book Regional Mechanics and Energetics of Stunned Myocardium in Vivo written by Serge Alexander Ivo Petrus Trines and published by . This book was released on 2001 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Energetics and Mechanics of the Myocardium During Anoxia and Reoxygenation by : Daneel Louise Leonora Dietrich
Download or read book Energetics and Mechanics of the Myocardium During Anoxia and Reoxygenation written by Daneel Louise Leonora Dietrich and published by . This book was released on 1992 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Simultaneous Measurement of the Mechanics and Energetics of Cardiac Trabeculae by : June-Chiew Han
Download or read book Simultaneous Measurement of the Mechanics and Energetics of Cardiac Trabeculae written by June-Chiew Han and published by . This book was released on 2011 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cardiac Energetics written by R. Jacob and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assessment of cardiac energetics at the level of ATP-synthesis, chemomechanical energy transformation and whole organ dynamics as a function of haemodynamic load, ventricular configuration and oxygen- and substrates supply is basic to understanding cardiac function under physiological and pathophysiological (hypertrophy, hypoxia, ischaemia and heart failure) conditions. Moreover, cardiac energetics should be an important consideration in the choice and application of drugs especially in the case of vasodilators, inotropic agents and in cardioprotective measures. Only by considering energetics at the subcellular, cellular, and whole-heart level we can arrive at a better understanding of cardiac performance and ultimately better clinical judgement and drug therapy. Quantification of myocardial energetics will also help to determine the optimal time for surgical interventions such as valvular replacement or aneurysm resection. The present volume is the outcome of an international symposium on cardiac energetics held in Gargellen/Montafon (Austria), June 1986. The contributions will certainly help bridge the existing gap between basic research involving isolated structures and that involving the whole organ, on the one hand, and render the results derived from basic research applicable to clinical problems, on the other hand.
Book Synopsis Cardiac Mechanics and Function in the Normal and Diseased Heart by : Masatsugu Hori
Download or read book Cardiac Mechanics and Function in the Normal and Diseased Heart written by Masatsugu Hori and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular dynamics is a field in which modelling and systems analysis have formed an extremely important discipline. For example, understanding of even such a fundamental function of the circulation as the relationship between central venous pressure apd cardiac output has required evolution of a pertinent model based on years of exhaustive ex perimental investigations by Starling, Starr, and Guyton. Hemodynamic analyses of pulsatile pressures and flows in the arteries and veins have been a continuing challenge taken up by champions of fluid dynamics such as Frank, Wetterer, Taylor, and Wormersley, just to mention a few names, and some kind of model was always proposed as a conceptual framework. An even greater challenge to cardiovascular dynamicists was how to analyze the intermittent coupling of the ventricle and the arterial or venous vasculature through the valve. The availability of numerical solutions by computer and the recently evolved ventricular model with a time-varying elastance and a pressure-dependent internal resistance opened the way to analysis of this coupling. The ever increasing speed of computers has also facilitated trips between the fre quency and the time domain, even on-line for some experimental studies. This book contains many analyses dedicated to the interactions between the heart and the vasculature, providing the reader with findings at the cutting edge of current research in this field.
Book Synopsis Energetics and Mechanics of Contraction of Isolated Papillary Muscle from Hearts with Ventricular Hypertrophy, Congestive Cardiac Failure, Cardiomyopathy and Enhanced Contractility by : John Francis Gunning
Download or read book Energetics and Mechanics of Contraction of Isolated Papillary Muscle from Hearts with Ventricular Hypertrophy, Congestive Cardiac Failure, Cardiomyopathy and Enhanced Contractility written by John Francis Gunning and published by . This book was released on 1972 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cardiovascular Soft Tissue Mechanics by : Stephen C. Cowin
Download or read book Cardiovascular Soft Tissue Mechanics written by Stephen C. Cowin and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special volume of the Journal of Elasticity represents the first in a new p- gram dedicated to the occasional publication of collections of invited, reviewed papers of topical interest. The purpose of this program is to spotlight the dev- opments and applications in the mechanics of materials within specific areas that can enhance growth and provide insight for the advancement of the field as well as promote fundamental understanding and basic discovery. Soft Tissue Mechanics is an area of biomechanics that draws heavily upon f- damental ideas and material models from nonlinear elasticity and viscoelasticity. A major goal of this research is to understand those mechanics properties of heart, artery, collagen and skeletal muscle tissue that can be used for the diagnosis of health problems and the improvement of human life. This volume illustrates how experiment, modeling and computation is currently employed in this emerging field. May 2001 ROGER FOSDICK Editor-in-Chief Journal of Elasticity 61: ix–xii, 2000. ix Preface There are two primary areas for the application of elasticity in the biomechanics of tissues: hard tissue mechanics (e.g., bone, teeth, horns, etc.) and soft tissue - chanics (e.g., skin, tendons, arteries, etc.). The distinguishing feature between these tissue types is the amount of physiological “normal” deformation they experience. While “hard” tissues only experience small deformations, soft tissues typically experience large deformations. From a biomechanics viewpoint soft tissues fall within the realm of finite elasticity.
Book Synopsis Myocardial torsion by : Jorge C. Trainini
Download or read book Myocardial torsion written by Jorge C. Trainini and published by Editorial Biblos. This book was released on 2020-04-02 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial Torsion is a book different from others, simply because this book is unique, unusual, and I dare say with admiration, it is a curious book, partly magical, full of personality, for initiatory readers, revealing, provocative, challenging. The book has the infrequent peculiarity of being based, to a great extent, on original personal and multidisciplinary investigations, granting it an important extra value. The authors define their purpose since the firsts pages of the book: to provide solidity, validity and even more to Torrent Guasp's concepts. This is certainly a different book in its structure, content and elaboration. It is a text that the reader may admire or criticize, that may create skepticism or surprise at the new data it propose, but wich undoudtedly will leavenobody indifferent, and that is something few books can achieve.
Book Synopsis Coronary Circulation and Energetics of the Myocardium by : G. Marchetti
Download or read book Coronary Circulation and Energetics of the Myocardium written by G. Marchetti and published by . This book was released on 1967 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Systolic and Diastolic Function of the Heart by : Neil B. Ingels
Download or read book Systolic and Diastolic Function of the Heart written by Neil B. Ingels and published by IOS Press. This book was released on 1996 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapter 22: Crossbridge and Muscle Properties, Energetics, and Pressure-Volume Area -- Chapter 23: Constancy and Variability of Oxygen Costs of Mechanical Energy (PVA) and Contractility (Emax) -- Chapter 24: Tight Coupling between Regional Myocardial Oxygen Consumption and Contractile Function -- Chapter 25: Force-Frequency Relation, Force-Interval Relation, and Mechanical Restitution -- Chapter 26: Elastance-Based Mechanical Restitution Provides Data from the Intact Heart Not Available from Any Other Technique -- Chapter 27: Contractility Indices -- Chapter 28: Searching for Indices of Contractility Is Counterproductive -- Chapter 29: Rapid Contractile Upregulation Rematches Stroke Work to Increased Afterload Independent of Ventricular Geometry, Afterload-Related Coronary Perfusion Pressure Fluctuations and Baseline Contractile State -- Chapter 30: Wall Thickening, Shears, and Cleavage Planes -- Chapter 31: Mechanisms of Large Ventricular Wall Shortening and Thickening -- Chapter 32: Twisting, Torsion, and Other Shears -- Chapter 33: Ventricular Twist and Its Relationship to Pressure Volume and Shortening -- Chapter 34: Differences in Systolic and Diastolic Torsional Deformation of the Left Ventricle -- Chapter 35: Coronary Flow, Systolic Perfusion, and the "Gregg Phenomenon -- Chapter 36: Intramyocardial Hydraulic Regulation of Cardiac Mechanics and Energetics -- Chapter 37: Left Ventricular Afterload and Arterial Coupling -- Indexes -- Author Index -- Affiliation Index -- Subject Index
Book Synopsis Cardiac Mechanics: Physiological, Clinical, and Mathematical Considerations by : Israel Mirsky
Download or read book Cardiac Mechanics: Physiological, Clinical, and Mathematical Considerations written by Israel Mirsky and published by . This book was released on 1974 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cardiac Energetics: From Emax to Pressure-Volume Area by : Martin M. LeWinter
Download or read book Cardiac Energetics: From Emax to Pressure-Volume Area written by Martin M. LeWinter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of the progress in cardiac energetics in recent years has been spurred by the pressure-volume area concept, the natural extension into energetics of earlier pioneering work delineating the time-varying elastance framework for ventricular contraction. The book draws together a broad spectrum of researchers - basic, applied and clinical - having a shared interest in the energetics of cardiac muscle and ventricle, providing an overview of the current state of the art.
Book Synopsis Mechanics of the Circulation by : H. E. D. J. ter Keurs
Download or read book Mechanics of the Circulation written by H. E. D. J. ter Keurs and published by Springer. This book was released on 1987-07-31 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume constitutes the proceedings of a satellite symposium of the XXXth congress of the International Union of Physiological Sciences. The symposium has been held In Banff, Alberta Canada July 9-11 1986. The program was organized to provide a selective overview of current developments in cardiac biophysics, biochemistry, and physiology. In order to highlight areas of develop ing ideas and to stimulate the participants' inquisitiveness into the nature and complexity of the integrated cardiovascular system, lectures and discussions were presented that emphasized evolving and sometimes provocative concepts in the field. With the same goal in mind we have, for the readers of this volume, briefly summarized the general discussions. We would like to thank several individuals whose dedication made this sym posium and publication of the proceedings possible. Mrs. Lois Kokoski and Mrs. Madeleine Aldridge of the Conference Office of the University of Calgary seemingly effortlessly handled the details of the symposium. Peter de Tombe, Dr. Peter Backx and Dr. Jeroen Bucx transcribed the general discussions. Finally, we appreciate the extra effort of our secretaries, Lenore Doell and Gregory Douglas, and the work of Anna Tyberg who prepared the final manuscripts for publication. Henk E.D.J. ter Keurs, M.D. Ph.D. John V. Tyberg, M.D. Ph.D.
Book Synopsis The Mechano-energetics of the Heart by : Lauren Dupuis
Download or read book The Mechano-energetics of the Heart written by Lauren Dupuis and published by . This book was released on 2014 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: To determine the mechanical and energetic properties of the heart, experiments are commonly performed on both the whole organ and cardiac trabeculae. In both of these models, the sarcomere is the fundamental contractile unit of muscle, and is activated by calcium. Although the role of calcium in muscle contraction has been well characterised, there are currently no experimental data or computational models which describe its behavior during a work-loop. In this study, the ter Keurs calcium model was successfully paired with the Rice-Tran cross-bridge model. This allowed me to explore the behavior of the free cytosolic calcium concentration during the contractile cycle as well as to study more accurately the mechano-energetic behavior of sarcomere dynamics. The results made clear that as the force developed by the sarcomere waned during the relaxation phase of the twitch (in response to the decline of the calcium transient), Troponin-C released a portion of its bound Ca2+, thus producing a second surge in free cytosolic calcium. Such behaviour has been repeatedly observed in isometric, but not work-loop, contractions. Given the successful performance of the integrated cellular model, I implemented it within an existing model of the left ventricle. Simulations qualitatively reproduced general trends seen experimentally. Most importantly, pressure-volume loops produced by the 3-D, whole-heart model matched experimental data.
Author :Gerhard A. Holzapfel Publisher :Springer Science & Business Media ISBN 13 :9783211004555 Total Pages :360 pages Book Rating :4.0/5 (45 download)
Book Synopsis Biomechanics of Soft Tissue in Cardiovascular Systems by : Gerhard A. Holzapfel
Download or read book Biomechanics of Soft Tissue in Cardiovascular Systems written by Gerhard A. Holzapfel and published by Springer Science & Business Media. This book was released on 2003-05-06 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is written by leading experts in the field presenting an up-to-date view of the subject matter in a didactically sound manner. It presents a review of the current knowledge of the behaviour of soft tissues in the cardiovascular system under mechanical loads, and the importance of constitutive laws in understanding the underlying mechanics is highlighted. Cells are also described together with arteries, tendons and ligaments, heart, and other biological tissues of current research interest in biomechanics. This includes experimental, continuum mechanical and computational perspectives, with the emphasis on nonlinear behaviour, and the simulation of mechanical procedures such as balloon angioplasty.
