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Mapping The Human Brains Cortical Subcortical Functional Network Organization
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Book Synopsis Micro-, Meso- and Macro-Connectomics of the Brain by : Henry Kennedy
Download or read book Micro-, Meso- and Macro-Connectomics of the Brain written by Henry Kennedy and published by Springer. This book was released on 2016-03-10 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Book Synopsis Discovering the Brain by : National Academy of Sciences
Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
Book Synopsis Fundamentals of Brain Network Analysis by : Alex Fornito
Download or read book Fundamentals of Brain Network Analysis written by Alex Fornito and published by Academic Press. This book was released on 2016-03-04 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. - Winner of the 2017 PROSE Award in Biomedicine & Neuroscience and the 2017 British Medical Association (BMA) Award in Neurology - Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems - Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience - Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain
Book Synopsis Callosal Agenesis by : Maryse Lassone
Download or read book Callosal Agenesis written by Maryse Lassone and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to the description of agenesis of the corpus callosum, a congenital malformation of midline structures in the brain that may be regarded as a natural model of the "split-brain. " First reported by Rei! in 1812, this anomaly has since been described by several investigators. Interest in this malformation was revived in the 1970s by studies of interhemispheric transfer in Bogen and Vogel's commissurotomized patients and the subsequent findings by Sperry that acallosal patients were devoid of the typical disconnection deficits found in patients with surgical transection of the corpus callosum. Since this seminal work, the bulk of neuropsychological research on callosal agenesis has focused on the particulars of interhemispheric transfer and integration. An ever-growing literature has emerged on the subject, attempting to specify the extent and limits of neural plasticity in a nervous system that has evolved in the absence of the most important interhemispheric pathway. Whilst callosal agenesis proves to be an excellent model of cerebral plasticity, it has to be pointed out that this anomaly is often associated with other malformations and neurological diseases that may result in different degrees of mental retardation or other cognitive and sensorimotor deficits. In this context, neurological research on callosal agenesis has concentrated on the description of various syndromes associated with this pathology as well as on the attempt to specify its neurobehavioral manifestations.
Book Synopsis Principles of Behavioral and Cognitive Neurology by : M.-Marsel Mesulam
Download or read book Principles of Behavioral and Cognitive Neurology written by M.-Marsel Mesulam and published by Oxford University Press. This book was released on 2000-01-27 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised new edition of a classic book provides a clinically inspired but scientifically guided approach to the biological foundations of human mental function in health and disease. It includes authoritative coverage of all the major areas related to behavioral neurology, neuropsychology, and neuropsychiatry. Each chapter, written by a world-renowned expert in the relevant area, provides an introductory background as well as an up-to-date review of the most recent developments. Clinical relevance is emphasized but is placed in the context of cognitive neuroscience, basic neuroscience, and functional imaging. Major cognitive domains such as frontal lobe function, attention and neglect, memory, language, prosody, complex visual processing, and object identification are reviewed in detail. A comprehensive chapter on behavioral neuroanatomy provides a background for brain-behavior interactions in the cerebral cortex, limbic system, basal ganglia, thalamus, and cerebullum. Chapters on temperolimbic epilepsy, major psychiatric syndromes, and dementia provide in-depth analyses of these neurobehavioral entities and their neurobiological coordinates. Changes for this second edition include the reflection throughout the book of the new and flourishing alliance of behavioral neurology, neuropsychology, and neuropsychiatry with cognitive science;major revision of all chapters; new authorship of those on language and memory; and the inclusion of entirely new chapters on psychiatric syndromes and the dementias. Both as a textbook and a reference work, the second edition of Principles of Behavioral and Cognitive Neurology represents an invaluable resource for behavioral neurologists, neuropsychologists, neuropsychiatrists, cognitive and basic neuroscientists, geriatricians, physiatrists, and their students and trainees.
Book Synopsis Atlas of Human Brain Connections by : Marco Catani
Download or read book Atlas of Human Brain Connections written by Marco Catani and published by Oxford University Press, USA. This book was released on 2012-06-14 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major challenges of modern neuroscience is to define the complex pattern of neural connections that underlie cognition and behaviour. This atlas capitalises on novel diffusion MRI tractography methods to provide a comprehensive overview of connections derived from virtual in vivo tractography dissections of the human brain.
Book Synopsis Handbook of Neuroengineering by : Nitish V. Thakor
Download or read book Handbook of Neuroengineering written by Nitish V. Thakor and published by Springer Nature. This book was released on 2023-02-02 with total page 3686 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook serves as an authoritative reference book in the field of Neuroengineering. Neuroengineering is a very exciting field that is rapidly getting established as core subject matter for research and education. The Neuroengineering field has also produced an impressive array of industry products and clinical applications. It also serves as a reference book for graduate students, research scholars and teachers. Selected sections or a compendium of chapters may be used as “reference book” for a one or two semester graduate course in Biomedical Engineering. Some academicians will construct a “textbook” out of selected sections or chapters. The Handbook is also meant as a state-of-the-art volume for researchers. Due to its comprehensive coverage, researchers in one field covered by a certain section of the Handbook would find other sections valuable sources of cross-reference for information and fertilization of interdisciplinary ideas. Industry researchers as well as clinicians using neurotechnologies will find the Handbook a single source for foundation and state-of-the-art applications in the field of Neuroengineering. Regulatory agencies, entrepreneurs, investors and legal experts can use the Handbook as a reference for their professional work as well.
Book Synopsis Brain Repair After Stroke by : Steven C. Cramer
Download or read book Brain Repair After Stroke written by Steven C. Cramer and published by Cambridge University Press. This book was released on 2010-10-28 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.
Book Synopsis The Human Amygdala by : Paul J. Whalen
Download or read book The Human Amygdala written by Paul J. Whalen and published by Guilford Press. This book was released on 2009-01-01 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on pioneering animal studies, and making use of new, noninvasive techniques for studying the human brain, research on the human amygdala has blossomed in recent years. This comprehensive volume brings together leading authorities to synthesize current knowledge on the amygdala and its role in psychological function and dysfunction. Initial chapters discuss how animal models have paved the way for work with human subjects. Next, the book examines the amygdala's involvement in emotional processing, learning, memory, and social interaction. The final section presents key advances in understanding specific clinical disorders: anxiety disorders, depression, schizophrenia, autism, and Alzheimer's disease. Illustrations include more than 25 color plates.
Book Synopsis The Thalamus by : Michael M. Halassa
Download or read book The Thalamus written by Michael M. Halassa and published by Cambridge University Press. This book was released on 2022-09-01 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thalamus is a key structure in the mammalian brain, providing a hub for communication within and across distributed forebrain networks. Research in this area has undergone a revolution in the last decade, with findings that suggest an expanded role for the thalamus in sensory processing, motor control, arousal regulation, and cognition. Moving beyond previous studies of anatomy and cell neurochemistry, scientists have expanded into investigations of cognitive function, and harness new methods and theories of neural computation. This book provides a survey of topics at the cutting edge of this field, covering basic anatomy, evolution, development, physiology and computation. It is also the first book to combine these disciplines in one place, highlighting the interdisciplinary nature of thalamus research, and will be an essential resource for students and experts in biology, medicine and computer science.
Book Synopsis The Cambridge Handbook of Cognitive Development by : Olivier Houdé
Download or read book The Cambridge Handbook of Cognitive Development written by Olivier Houdé and published by Cambridge University Press. This book was released on 2022-03-03 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: How does cognition develop in infants, children and adolescents? This handbook presents a cutting-edge overview of the field of cognitive development, spanning basic methodology, key domain-based findings and applications. Part One covers the neurobiological constraints and laws of brain development, while Part Two covers the fundamentals of cognitive development from birth to adulthood: object, number, categorization, reasoning, decision-making and socioemotional cognition. The final Part Three covers educational and school-learning domains, including numeracy, literacy, scientific reasoning skills, working memory and executive skills, metacognition, curiosity-driven active learning and more. Featuring chapters written by the world's leading scholars in experimental and developmental psychology, as well as in basic neurobiology, cognitive neuroscience, computational modelling and developmental robotics, this collection is the most comprehensive reference work to date on cognitive development of the twenty-first century. It will be a vital resource for scholars and graduate students in developmental psychology, neuroeducation and the cognitive sciences.
Download or read book The Claustrum written by John R. Smythies and published by Academic Press. This book was released on 2013-11-11 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present day is witnessing an explosion of our understanding of how the brain works at all levels, in which complexity is piled on complexity, and mechanisms of astonishing elegance are being continually discovered. This process is most developed in the major areas of the brain, such as the cortex, thalamus, and striatum. The Claustrum instead focuses on a small, remote, and, until recently, relatively unknown area of the brain. In recent years, researchers have come to believe that the claustrum is concerned with consciousness, a bold hypothesis supported by the claustrum's two-way connections with nearly every other region of the brain and its seeming involvement with multisensory integrations—the hallmark of consciousness. The claustrum, previously in a humble position at the back of the stage, might in fact be the conductor of the brain's orchestra. The Claustrum brings together leading experts on the claustrum from the varied disciplines of neuroscience, providing a state-of-the-art presentation of what is currently known about the claustrum, promising lines of current research (including epigenetics), and projections of new lines of investigation on the horizon. - Develops a unifying hypothesis about the claustrum's role in consciousness, as well as the integration of sensory information and other higher brain functions - Discusses the involvement of the claustrum with autism, schizophrenia, epilepsy, Alzheimer's disease, and Parkinson's disease - Coverage of all aspects of the claustrum, from its evolution and development to promising new lines of research, including epigenetics, provides a platform and point of reference for future investigative efforts
Book Synopsis Essential Clinical Anatomy of the Nervous System by : Paul Rea
Download or read book Essential Clinical Anatomy of the Nervous System written by Paul Rea and published by Academic Press. This book was released on 2015-01-05 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Clinical Anatomy of the Nervous System is designed to combine the salient points of anatomy with typical pathologies affecting each of the major pathways that are directly applicable in the clinical environment. In addition, this book highlights the relevant clinical examinations to perform when examining a patient's neurological system, to demonstrate pathology of a certain pathway or tract. Essential Clinical Anatomy of the Nervous System enables the reader to easily access the key features of the anatomy of the brain and main pathways which are relevant at the bedside or clinic. It also highlights the typical pathologies and reasoning behind clinical findings to enable the reader to aid deduction of not only what is wrong with the patient, but where in the nervous system that the pathology is. - Anatomy of the brain and neurological pathways dealt with as key facts and summary tables essential to clinical practice. - Succinct yet comprehensive format with quick and easy access facts in clearly laid out key regions, common throughout the different neurological pathways. - Includes key features and hints and tips on clinical examination and related pathologies, featuring diagnostic summaries of potential clinical presentations.
Book Synopsis Functions of the Cortico-Basal Ganglia Loop by : Minoru Kimura
Download or read book Functions of the Cortico-Basal Ganglia Loop written by Minoru Kimura and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, which is based on the proceedings of the international symposium "Functional Linkages Between the Cerebral Cortex and Basal Ganglia in the Control of Voluntary Movement", held December 1993 in Osaka, Japan, the world's leading neuroscientists present the most up-to-date findings of current research on cortico-basal ganglia relations. Topics addressed in this book include the structure and function of basal ganglia cells and systems, the organization of thalamo-cortical systems, the frontal cortex, and clinical applications of ongoing studies. Of particular interest is the analysis of models of motor learning and functional schemes of cortico-basal ganglia and striatal circuitry. The valuable new insights this interdisciplinary work provides will benefit researchers and students in fields such as neurobiology, behavioral neurophysiology, neurochemistry, and neuropharmacology.
Book Synopsis Salience Network of the Human Brain by : Lucina Q. Uddin
Download or read book Salience Network of the Human Brain written by Lucina Q. Uddin and published by Academic Press. This book was released on 2016-08-24 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: Salience Network of the Human Brain focuses on the multiple sources of stimuli that compete for our attention, providing interesting discussions on how the relative salience—importance or prominence—of each of these inputs determines which ones we choose to focus on for more in-depth processing. The salience network is a collection of regions of the brain that select which stimuli are deserving of our attention. The network has key nodes in the insular cortex and is critical for detecting behaviorally relevant stimuli and for coordinating the brain's neural resources in response to these stimuli. The insular cortex is a complex and multipurpose structure that plays a role in numerous cognitive functions related to perception, emotion, and interpersonal experience—and the failure of this network to function properly can lead to numerous neuropsychiatric disorders, including autism spectrum disorder, psychosis, and dementia. - Presents the only publication available that summarizes our understanding of the salience network in one resource - Authored by a leading research on this important aspect of attention - Focuses on the multiple sources of stimuli that compete for our attention, providing interesting discussions on how the relative salience—importance or prominence—of each of these inputs determines which ones we choose to focus on for more in-depth processing
Book Synopsis Brain Injury Medicine, Third Edition by : Nathan D. Zasler, MD
Download or read book Brain Injury Medicine, Third Edition written by Nathan D. Zasler, MD and published by Springer Publishing Company. This book was released on 2021-09-01 with total page 1891 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This updated textbook was much needed as there has been increased attention in recent years toward brain injuries. The book provides updated guidelines and clinical practice recommendations that support the intended audience of trainees and current practitioners. This update makes it the current standard text for any brain injury specialist." ---Doody's Review Service, 4 stars This revised and greatly expanded Third Edition of Brain Injury Medicine continues its reputation as the key core textbook in the field, bringing together evidence-based medicine and years of collective author clinical experience in a clear and comprehensive guide for brain injury professionals. Universally praised as the gold standard text and go-to clinical reference, the book covers the entire continuum of care from early diagnosis and assessment through acute management, rehabilitation, associated medical and quality of life issues, and functional outcomes. With 12 new chapters and expanded coverage in key areas of pathobiology and neuro-recovery, special populations, sport concussion, disorders of consciousness, neuropharmacology, and more, this "state of the science" resource promotes a multi-disciplinary approach to a complex condition with consideration of emerging topics and the latest clinical advances. Written by over 200 experts from all involved disciplines, the text runs the full gamut of practice of brain injury medicine including principles of public health and research, biomechanics and neural recovery, neuroimaging and neurodiagnostic testing, sport and military, prognosis and outcome, acute care, treatment of special populations, neurologic and other medical complications post-injury, motor and musculoskeletal problems, post-trauma pain disorders, cognitive and behavioral problems, functional mobility, neuropharmacology and alternative treatments, community reentry, and medicolegal and ethical issues. Unique in its scope of topics relevant to professionals working with patients with brain injury, this third edition offers the most complete and contemporary review of clinical practice standards in the field. Key Features: Thoroughly revised and updated Third Edition of the seminal reference on brain injury medicine Evidence-based consideration of emerging topics with new chapters covering pathobiology, biomarkers, neurorehabilitation nursing, neurodegenerative dementias, anoxic/hypoxic ischemic brain injury, infectious causes of acquired brain injury, neuropsychiatric assessment, PTSD, and capacity assessment Multi-disciplinary authorship with leading experts from a wide range of specialties including but not limited to physiatry, neurology, psychiatry, neurosurgery, neuropsychology, physical therapy, occupational therapy speech language pathology, and nursing New online chapters on survivorship, family perspectives, and resources for persons with brain injury and their caregivers Purchase includes digital access for use on most mobile devices or computers
Book Synopsis Atlas of the Human Brainstem by : George Paxinos
Download or read book Atlas of the Human Brainstem written by George Paxinos and published by Elsevier. This book was released on 2013-10-22 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Work on the human brainstem has been impeded by the unavailability of a comprehensive diagrammatic and photographic atlas. In the authors' preliminary work on the morphology of the human brainstem (The Human Nervous System, 1990), Paxinos et al demonstrated that it is possible to use chemoarchitecture to establish a number of human homologs in structures known to exist in the rat, the most extensively studied species. Now, with the first detailed atlas on the human brainstem in more than forty years, the authors present an accurate, comprehensive, and convenient reference for students, researchers, and pathologists. Key Features * The first detailed atlas on the human brainstem in more than forty years * Delineated as accurately as The Rat Brain in Stereotaxic Coordinates, Second Edition (Paxinos/Watson, 1986), the most cited book in neuroscience * Based on a single brain from a 59-year-old male with no medical history of neurological or psychiatric illness * Represents all areas of the medulla, pons, and midbrain in the plane transverse to the longitudinal axis of the brainstem * Consists of 64 plates and 64 accompanying diagrams with an interplate distance of half a millimeter * The photographs are of Nissl and acetylcholinesterase (AChE) stained sections at alternate levels * Establishes systematically the human homologs to nuclei identified in the brainstem of the rat Reviewed by leading neuroanatomists * An accurate and convenient guide for students, researchers, and pathologists
