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Managing Discovery In The Life Sciences
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Book Synopsis Managing Discovery in the Life Sciences by : Philip A. Rea
Download or read book Managing Discovery in the Life Sciences written by Philip A. Rea and published by Cambridge University Press. This book was released on 2018-02 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses in roughly equal measure the science and management behind several recent marketable biomedical innovations.
Book Synopsis Managing Discovery in the Life Sciences by : Philip A. Rea
Download or read book Managing Discovery in the Life Sciences written by Philip A. Rea and published by Cambridge University Press. This book was released on 2018-02-01 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, distinguished scholars Philip A. Rea, Mark V. Pauly, and Lawton R. Burns explore the science and management behind marketable biomedical innovations. They look at how the science actually played out through the interplay of personalities, the cultures within and between academic and corporate entities, and the significance of serendipity not as a mysterious phenomenon but one intrinsic to the successes and failures of the experimental approach. With newly aggregated data and case studies, they consider the fundamental economic underpinnings of investor-driven discovery management, not as an obstacle or deficiency as its critics would contend or as something beyond reproach as some of its proponents might claim, but as the only means by which scientists and managers can navigate the unknowable to discover new products and decide how to sell them so as to maximize the likelihood of establishing a sustainable pipeline for still more marketable biomedical innovations.
Book Synopsis Innovative Research in Life Sciences by : E. Andrew Balas
Download or read book Innovative Research in Life Sciences written by E. Andrew Balas and published by John Wiley & Sons. This book was released on 2018-11-08 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: “I thoroughly enjoyed reading this book as it has taken me on a journey through time, across the globe and through multiple disciplines. Indeed, we need to be thinking about these concepts and applying them every day to do our jobs better.” Farah Magrabi, Macquarie University, Australia “The reader will find intriguing not only the title but also the content of the book. I’m also pleased that public health, and even more specifically epidemiology has an important place in this ambitious discussion.” Elena Andresen, Oregon Health & Science University, USA “This book is very well written and addresses an important topic. It presents many reasons why basic scientists/researchers should establish collaborations and access information outside traditional means and not limit thinking but rather expand such and perhaps develop more innovative and translational research ventures that will advance science and not move it laterally.” Gerald Pepe, Eastern Virginia Medical School, USA “This book gathers logically and presents interestingly (with many examples) the qualities and attitudes a researcher must possess in order to become successful. On the long run, the deep and carefully reexamined research will be the one that lasts.” Zoltán Néda, Babeş-Bolyai University, Romania “I really liked the five pillars delineating the components of humanism in research. This book has made a major contribution to the research ethics literature.” David Fleming, University of Missouri, USA A comprehensive review of the research phase of life sciences from design to discovery with suggestions to improve innovation This vital resource explores the creative processes leading to biomedical innovation, identifies the obstacles and best practices of innovative laboratories, and supports the production of effective science. Innovative Research in Life Sciences draws on lessons from 400 award-winning scientists and research from leading universities. The book explores the innovative process in life sciences and puts the focus on how great ideas are born and become landmark scientific discoveries. The text provides a unique resource for developing professional competencies and applied skills of life sciences researchers. The book examines what happens before the scientific paper is submitted for publication or the innovation becomes legally protected. This phase is the most neglected but most exciting in the process of scientific creativity and innovation. The author identifies twelve competencies of innovative biomedical researchers that described and analyzed. This important resource: Highlights the research phase from design to discovery that precedes innovation disclosure Offers a step by step explanation of how to improve innovation Offers solutions for improving research and innovation productivity in the life sciences Contains a variety of statistical databases and a vast number of stories about individual discoveries Includes a process of published studies and national statistics of biomedical research and reviews the performance of research labs and academic institutions Written for academics and researchers in biomedicine, pharmaceutical science, life sciences, drug discovery, pharmacology, Innovative Research in Life Sciences offers a guide to the creative processes leading to biomedical innovation and identifies the best practices of innovative scientists and laboratories.
Book Synopsis Innovative Research in Life Sciences by : E. Andrew Balas
Download or read book Innovative Research in Life Sciences written by E. Andrew Balas and published by John Wiley & Sons. This book was released on 2018-11-08 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: “I thoroughly enjoyed reading this book as it has taken me on a journey through time, across the globe and through multiple disciplines. Indeed, we need to be thinking about these concepts and applying them every day to do our jobs better.” Farah Magrabi, Macquarie University, Australia “The reader will find intriguing not only the title but also the content of the book. I’m also pleased that public health, and even more specifically epidemiology has an important place in this ambitious discussion.” Elena Andresen, Oregon Health & Science University, USA “This book is very well written and addresses an important topic. It presents many reasons why basic scientists/researchers should establish collaborations and access information outside traditional means and not limit thinking but rather expand such and perhaps develop more innovative and translational research ventures that will advance science and not move it laterally.” Gerald Pepe, Eastern Virginia Medical School, USA “This book gathers logically and presents interestingly (with many examples) the qualities and attitudes a researcher must possess in order to become successful. On the long run, the deep and carefully reexamined research will be the one that lasts.” Zoltán Néda, Babeş-Bolyai University, Romania “I really liked the five pillars delineating the components of humanism in research. This book has made a major contribution to the research ethics literature.” David Fleming, University of Missouri, USA A comprehensive review of the research phase of life sciences from design to discovery with suggestions to improve innovation This vital resource explores the creative processes leading to biomedical innovation, identifies the obstacles and best practices of innovative laboratories, and supports the production of effective science. Innovative Research in Life Sciences draws on lessons from 400 award-winning scientists and research from leading universities. The book explores the innovative process in life sciences and puts the focus on how great ideas are born and become landmark scientific discoveries. The text provides a unique resource for developing professional competencies and applied skills of life sciences researchers. The book examines what happens before the scientific paper is submitted for publication or the innovation becomes legally protected. This phase is the most neglected but most exciting in the process of scientific creativity and innovation. The author identifies twelve competencies of innovative biomedical researchers that described and analyzed. This important resource: Highlights the research phase from design to discovery that precedes innovation disclosure Offers a step by step explanation of how to improve innovation Offers solutions for improving research and innovation productivity in the life sciences Contains a variety of statistical databases and a vast number of stories about individual discoveries Includes a process of published studies and national statistics of biomedical research and reviews the performance of research labs and academic institutions Written for academics and researchers in biomedicine, pharmaceutical science, life sciences, drug discovery, pharmacology, Innovative Research in Life Sciences offers a guide to the creative processes leading to biomedical innovation and identifies the best practices of innovative scientists and laboratories.
Book Synopsis Scientific Discovery in the Social Sciences by : Mark Addis
Download or read book Scientific Discovery in the Social Sciences written by Mark Addis and published by Springer Nature. This book was released on 2019-09-12 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers selected papers exploring issues arising from scientific discovery in the social sciences. It features a range of disciplines including behavioural sciences, computer science, finance, and statistics with an emphasis on philosophy. The first of the three parts examines methods of social scientific discovery. Chapters investigate the nature of causal analysis, philosophical issues around scale development in behavioural science research, imagination in social scientific practice, and relationships between paradigms of inquiry and scientific fraud. The next part considers the practice of social science discovery. Chapters discuss the lack of genuine scientific discovery in finance where hypotheses concern the cheapness of securities, the logic of scientific discovery in macroeconomics, and the nature of that what discovery with the Solidarity movement as a case study. The final part covers formalising theories in social science. Chapters analyse the abstract model theory of institutions as a way of representing the structure of scientific theories, the semi-automatic generation of cognitive science theories, and computational process models in the social sciences. The volume offers a unique perspective on scientific discovery in the social sciences. It will engage scholars and students with a multidisciplinary interest in the philosophy of science and social science.
Book Synopsis Open Source Software in Life Science Research by : Lee Harland
Download or read book Open Source Software in Life Science Research written by Lee Harland and published by Elsevier. This book was released on 2012-10-31 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems. The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an ‘omics’ platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. Discusses a broad range of applications from a variety of sectors Provides a unique perspective on work normally performed behind closed doors Highlights the criteria used to compare and assess different approaches to solving problems
Book Synopsis Data Integration in the Life Sciences by : Helena Galhardas
Download or read book Data Integration in the Life Sciences written by Helena Galhardas and published by Springer. This book was released on 2014-07-05 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 10th International Conference on Data Integration in the Life Sciences, DILS 2014, held in Lisbon, Portugal, in July 2014. The 9 revised full papers and the 5 short papers included in this volume were carefully reviewed and selected from 20 submissions. The papers cover a range of important topics such as data integration platforms and applications; biodiversity data management; ontologies and visualization; linked data and query processing.
Book Synopsis Knowledge Discovery, Knowledge Engineering and Knowledge Management by : Ana Fred
Download or read book Knowledge Discovery, Knowledge Engineering and Knowledge Management written by Ana Fred and published by Springer. This book was released on 2013-01-05 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-conference proceedings of the Second International Joint Conference on Knowledge Discovery, Knowledge Engineering, and Knowledge Management, IC3K 2010, held in Valencia, Spain, in October 2010. This book includes revised and extended versions of a strict selection of the best papers presented at the conference; 26 revised full papers together with 2 invited lectures were carefully reviewed and selected from 369 submissions. According to the three covered conferences KDIR 2010, KEOD 2010, and KMIS 2010, the papers are organized in topical sections on knowledge discovery and information retrieval, knowledge engineering and ontology development, and on knowledge management and information sharing.
Book Synopsis Managing the Drug Discovery Process by : Susan Miller
Download or read book Managing the Drug Discovery Process written by Susan Miller and published by Woodhead Publishing. This book was released on 2016-11-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effective thoroughly examines the current state of pharmaceutical research and development by providing chemistry-based perspectives on biomedical research, drug hunting and innovation. The book also considers the interplay of stakeholders, consumers, and the drug firm with attendant factors, including those that are technical, legal, economic, demographic, political, social, ecological, and infrastructural. Since drug research can be a high-risk, high-payoff industry, it is important to researchers to effectively and strategically manage the drug discovery process. This book takes a closer look at increasing pre-approval costs for new drugs and examines not only why these increases occur, but also how they can be overcome to ensure a robust pharmacoeconomic future. Written in an engaging manner and including memorable insights, this book is aimed at redirecting the drug discovery process to make it more efficient and cost-effective in order to achieve the goal of saving countless more lives through science. A valuable and compelling resource, this is a must-read for all students and researchers in academia and the pharmaceutical industry.
Book Synopsis Life Science Management by : Avo Schönbohm
Download or read book Life Science Management written by Avo Schönbohm and published by Springer Nature. This book was released on 2022-07-14 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The COVID-19 pandemic has reminded us of how important the life science industry is, and compels us to find efficient management methods specific to the industry. Pharmaceuticals, drug and vaccine development labs, R&D labs, medical instrumentation, and tech companies, hygiene supply companies, medical distribution chains, all form an integral part of this industry. At the interface of scientific research, technology, innovation and management and embedded in regulatory and legal frameworks, life science management is still an under-researched field of practice and science. This edited volume addresses this research gap and offers a wide range of practical and theoretical contributions that provide insights into one of the most exciting industries. The book is primarily directed at practitioners and decision makers in the life science industry. Students and professionals of life science management at all levels as well as policy makers will find valuable insights and inspiration for their daily work and career development.
Book Synopsis Managing the Drug Discovery Process by : Walter Moos
Download or read book Managing the Drug Discovery Process written by Walter Moos and published by Woodhead Publishing. This book was released on 2016-11-08 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effective thoroughly examines the current state of pharmaceutical research and development by providing chemistry-based perspectives on biomedical research, drug hunting and innovation. The book also considers the interplay of stakeholders, consumers, and the drug firm with attendant factors, including those that are technical, legal, economic, demographic, political, social, ecological, and infrastructural. Since drug research can be a high-risk, high-payoff industry, it is important to researchers to effectively and strategically manage the drug discovery process. This book takes a closer look at increasing pre-approval costs for new drugs and examines not only why these increases occur, but also how they can be overcome to ensure a robust pharmacoeconomic future. Written in an engaging manner and including memorable insights, this book is aimed at redirecting the drug discovery process to make it more efficient and cost-effective in order to achieve the goal of saving countless more lives through science. A valuable and compelling resource, this is a must-read for all students and researchers in academia and the pharmaceutical industry. Considers drug discovery in multiple R&D venues, including big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable
Book Synopsis Flow Cytometry by : Alice Longobardi Givan
Download or read book Flow Cytometry written by Alice Longobardi Givan and published by John Wiley & Sons. This book was released on 2013-04-10 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flow cytometry continually amazes scientists with its ever-expanding utility. Advances in flow cytometry have opened new directions in theoretical science, clinical diagnosis, and medical practice. The new edition of Flow Cytometry: First Principles provides a thorough update of this now classic text, reflecting innovations in the field while outlining the fundamental elements of instrumentation, sample preparation, and data analysis. Flow Cytometry: First Principles, Second Edition explains the basic principles of flow cytometry, surveying its primary scientific and clinical applications and highlighting state-of-the-art techniques at the frontiers of research. This edition contains extensive revisions of all chapters, including new discussions on fluorochrome and laser options for multicolor analysis, an additionalsection on apoptosis in the chapter on DNA, and new chapters onintracellular protein staining and cell sorting, including high-speed sorting and alternative sorting methods, as well as traditional technology. This essential resource: Assumes no prior knowledge of flow cytometry Progresses with an informal, engaging lecture style from simpleto more complex concepts Offers a clear introduction to new vocabulary, principles of instrumentation, and strategies for data analysis Emphasizes the theory relevant to all flow cytometry, with examples from a variety of clinical and scientific fields Flow Cytometry: First Principles, Second Edition provides scientists, clinicians, technologists, and students with the knowledge necessary for beginning the practice of flow cytometry and for understanding related literature.
Book Synopsis The Management of Technological Innovation by : Mark Dodgson
Download or read book The Management of Technological Innovation written by Mark Dodgson and published by Oxford University Press on Demand. This book was released on 2008-02-07 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: "By explaining the innovation process the book reveals the broad scope of MTI and its importance for company survival, growth and sustainability. It describes how MTI has to be managed strategically and how this is successfully achieved by formulating and implementing strategy and delivering value. Chapters provide frameworks, tools and techniques, and case studies on managing: innovation strategy, communities, and networks, R&D, design and new product and service development, operations and production, and commercialization." "This new edition has been fully revised and updated to reflect the latest teaching and research, and to ensure its continuing relevance to the contemporary world of MTI. It will be an important resource for academics, students, and managers throughout the world, is a recommended text for students of innovation and technology management at postgraduate and undergraduate level, and is particularly valuable for MBA courses."--BOOK JACKET.
Book Synopsis Managing Scientific Information and Research Data by : Svetla Baykoucheva
Download or read book Managing Scientific Information and Research Data written by Svetla Baykoucheva and published by Chandos Publishing. This book was released on 2015-07-14 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Innovative technologies are changing the way research is performed, preserved, and communicated. Managing Scientific Information and Research Data explores how these technologies are used and provides detailed analysis of the approaches and tools developed to manage scientific information and data. Following an introduction, the book is then divided into 15 chapters discussing the changes in scientific communication; new models of publishing and peer review; ethics in scientific communication; preservation of data; discovery tools; discipline-specific practices of researchers for gathering and using scientific information; academic social networks; bibliographic management tools; information literacy and the information needs of students and researchers; the involvement of academic libraries in eScience and the new opportunities it presents to librarians; and interviews with experts in scientific information and publishing. Promotes innovative technologies for creating, sharing and managing scientific content Presents new models of scientific publishing, peer review, and dissemination of information Serves as a practical guide for researchers, students, and librarians on how to discover, filter, and manage scientific information Advocates for the adoption of unique author identifiers such as ORCID and ResearcherID Looks into new tools that make scientific information easy to discover and manage Shows what eScience is and why it is becoming a priority for academic libraries Demonstrates how Electronic Laboratory Notebooks can be used to record, store, share, and manage research data Shows how social media and the new area of Altmetrics increase researchers’ visibility and measure attention to their research Directs to sources for datasets Provides directions on choosing and using bibliographic management tools Critically examines the metrics used to evaluate research impact Aids strategic thinking and informs decision making
Book Synopsis The Business of Healthcare Innovation by : Lawton Robert Burns
Download or read book The Business of Healthcare Innovation written by Lawton Robert Burns and published by Cambridge University Press. This book was released on 2020-03-12 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tech sectors are the least understood portion of the healthcare system, but the ones that supply most of the innovation in healthcare services and generate most revenue. Fully updated for this third edition, The Business of Healthcare Innovation is a wide-ranging analysis of business models and trends in the tech sectors of the healthcare industry. It provides a thorough overview of and introduction to the innovative sectors that fuel improvements in healthcare: pharmaceuticals, biotechnology, life science startups, medical devices and information technology. For each sector, the book examines the trends in scientific innovation, the science behind that innovation, the business and revenue models pursued to commercialize that innovation, the regulatory constraints within which each sector must operate and the growing issues posed by activist payers and consumers. From a combination of academic and industry perspectives, the authors show why healthcare sectors are such an important source of growth in any nation's economy.
Book Synopsis Calculus for the Life Sciences: A Modeling Approach by : James L. Cornette
Download or read book Calculus for the Life Sciences: A Modeling Approach written by James L. Cornette and published by American Mathematical Soc.. This book was released on 2019-05-25 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calculus for the Life Sciences is an entire reimagining of the standard calculus sequence with the needs of life science students as the fundamental organizing principle. Those needs, according to the National Academy of Science, include: the mathematical concepts of change, modeling, equilibria and stability, structure of a system, interactions among components, data and measurement, visualization, and algorithms. This book addresses, in a deep and significant way, every concept on that list. The book begins with a primer on modeling in the biological realm and biological modeling is the theme and frame for the entire book. The authors build models of bacterial growth, light penetration through a column of water, and dynamics of a colony of mold in the first few pages. In each case there is actual data that needs fitting. In the case of the mold colony that data is a set of photographs of the colony growing on a ruled sheet of graph paper and the students need to make their own approximations. Fundamental questions about the nature of mathematical modeling—trying to approximate a real-world phenomenon with an equation—are all laid out for the students to wrestle with. The authors have produced a beautifully written introduction to the uses of mathematics in the life sciences. The exposition is crystalline, the problems are overwhelmingly from biology and interesting and rich, and the emphasis on modeling is pervasive. An instructor's manual for this title is available electronically to those instructors who have adopted the textbook for classroom use. Please send email to [email protected] for more information. Online question content and interactive step-by-step tutorials are available for this title in WebAssign. WebAssign is a leading provider of online instructional tools for both faculty and students.
Book Synopsis Managing the Drug Discovery Process by : Susan Miller
Download or read book Managing the Drug Discovery Process written by Susan Miller and published by Elsevier. This book was released on 2023-01-15 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing chemistry-based perspectives on biomedical research, drug hunting and innovation. The book also considers the interplay of stakeholders, consumers and the drug firm with attendant factors, including those that are technical, legal, economic, demographic, political, social, ecological and infrastructural. This new edition takes a closer look at increasing pre-approval costs for new drugs and examines not only why these increases occur, but also how they can be overcome to ensure a robust pharmacoeconomic future. Since drug research can be a high-risk, high-payoff industry, it is important to researchers to effectively and strategically manage the drug discovery process. All chapters in this new release have been revised and expanded with new discussions on genetic and epigenetic advances, including CRISPR, exosomes, immuno-oncology approaches, including checkpoint inhibitors and CAR-T, antibiotics, entrepreneurship, and AI. Considers drug discovery in multiple R&D venues, including big pharma, large biotech, start-up ventures, academia and nonprofit research institutes Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable Addresses new areas, including gene editing technologies like CRISPR, personalized medicine, ethical and moral issues, data visualization, statistical representations, AI and machine learning
