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Author : A. John Kenny
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 384 pages
Book Rating : 4.3/5 (91 download)
Download or read book Mammalian Ectoenzymes written by A. John Kenny and published by Elsevier Publishing Company. This book was released on 1987 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9780444802347
Total Pages : 359 pages
Book Rating : 4.8/5 (23 download)
Download or read book Mammalian Ectoenzymes written by and published by . This book was released on 1987 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Georg W. Kreutzberg
Publisher : Springer Science & Business Media
ISBN 13 : 3642706649
Total Pages : 313 pages
Book Rating : 4.6/5 (427 download)
Download or read book Cellular Biology of Ectoenzymes written by Georg W. Kreutzberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells do not normally live as single entities but are grouped together in specific functional and structural configurations in various tissues. Intra cellular mechanisms maintain cellular viability and provide the means necessary for their specific cellular functions. The interaction between cells is maintained by mechanisms involving extracellular signalling. Such extracellular mechanisms may include special properties of the cell surface which involve immediate cell contact, but may also represent mechanisms which act at a distance and are mediated via special secretions and/or re ceptors. Recent studies on cell-cell contact have tended to stress cell sur face components directly mediating cellular interactions; the extracellular medium as a metabolically active compartment has been rather neglected. However, it represents a vital medium through which cells communicate, being important in, for example, chemotaxis in primitive organisms, and in devel~ment and in the coordination of multiple functions in multi cellular 0 ganisms. It is not surprising, therefore, that a number of mole cular me anisms have developed together with increasing biological complexi during evolution. Two aspects of the extracellular space have received increasing attention in the last few years. First, several macro molecules such as collagen, laminin and fibronectin have been identified as components of an extracellular matrix giving a structural dimension to the extracellular compartment.
Author : Georg W. Kreutzberg
Publisher : Springer
ISBN 13 :
Total Pages : 334 pages
Book Rating : 4.3/5 (91 download)
Download or read book Cellular Biology of Ectoenzymes written by Georg W. Kreutzberg and published by Springer. This book was released on 1986 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells do not normally live as single entities but are grouped together in specific functional and structural configurations in various tissues. Intra cellular mechanisms maintain cellular viability and provide the means necessary for their specific cellular functions. The interaction between cells is maintained by mechanisms involving extracellular signalling. Such extracellular mechanisms may include special properties of the cell surface which involve immediate cell contact, but may also represent mechanisms which act at a distance and are mediated via special secretions and/or re ceptors. Recent studies on cell-cell contact have tended to stress cell sur face components directly mediating cellular interactions; the extracellular medium as a metabolically active compartment has been rather neglected. However, it represents a vital medium through which cells communicate, being important in, for example, chemotaxis in primitive organisms, and in devel̃ment and in the coordination of multiple functions in multi cellular 0 ganisms. It is not surprising, therefore, that a number of mole cular me anisms have developed together with increasing biological complexi during evolution. Two aspects of the extracellular space have received increasing attention in the last few years. First, several macro molecules such as collagen, laminin and fibronectin have been identified as components of an extracellular matrix giving a structural dimension to the extracellular compartment.
Author : Albert Teelken
Publisher : Springer Science & Business Media
ISBN 13 : 9780306457050
Total Pages : 1256 pages
Book Rating : 4.4/5 (57 download)
Download or read book Neurochemistry written by Albert Teelken and published by Springer Science & Business Media. This book was released on 1997 with total page 1256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compiles 195 contributions from the June 1996 meeting. Part I (clinical aspects and pathology) discusses the role of neuroprotection and neurorescue in ischemia, stroke, and neuronal injury, as well as neurochemical mechanisms, mood disorders, and the significance of cerebrospinal fluid examinations for diagnosis and treatment. Part II (cellular functions) covers nutrient transport, energy metabolism, and metabolic trafficking in brain cells, and the role of neurotrophic molecules. Part III (molecules/methods) describes functional aspects of neuroactive compounds, with a special focus upon acetylocholine, taurine, amino acid neurotransmitters, and neuropeptides. Also discusses the role of lipid mediators, brain proteins, and new insights in methodology. Annotation copyrighted by Book News, Inc., Portland, OR
Author : Jose Vina
Publisher : CRC Press
ISBN 13 : 1351364405
Total Pages : 392 pages
Book Rating : 4.3/5 (513 download)
Download or read book Glutathione (1990) written by Jose Vina and published by CRC Press. This book was released on 2017-11-22 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this important book is to present the reader with developments concerning glutathione research. This work focuses on the synthesis-degradation and oxidation-reduction cycles of glutathione, the physiological functions of glutathione (especially in mammalian cells), and the analytical methods used to accurately measure the glutathione status of cells. This resource addresses specific modification of glutathione metabolism that is of special interest in the treatment of some tumors. This rare volume also introduces some different, new techniques on how to accurately measure glutathione, specifically in its oxidized form. Anyone involved with biochemistry, physiology, toxicology, pharmacology, nutrition and radiation biology will find this publication interesting and filled with useful information. It is also a valuable reference for research scientists in such fields as aging, metabolism disorders, and glutathione research.
Author : Alan J. Barrett
Publisher : Academic Press
ISBN 13 : 0123822203
Total Pages : 4097 pages
Book Rating : 4.1/5 (238 download)
Download or read book Handbook of Proteolytic Enzymes written by Alan J. Barrett and published by Academic Press. This book was released on 2012-10-30 with total page 4097 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more. The only comprehensive book on proteolytic enzymes Includes 671 chapters, each written by experts in their field, on proteolytic enzymes from all groups of living organisms and the viruses, including those that are currently major targets of pharmaceutical research Accompanying CD-ROM provides fully searchable text, 2D structures of peptidases in color and links directly to PubMed and MEROPS databases Each chapter describes in detail the enzyme name, its history, activity and specificity, structural chemistry, preparation, biological aspects and distinguishing features Over 1000 peptidases included
Author : S.C. Makrides
Publisher : Newnes
ISBN 13 : 0080930352
Total Pages : 776 pages
Book Rating : 4.0/5 (89 download)
Download or read book Gene Transfer and Expression in Mammalian Cells written by S.C. Makrides and published by Newnes. This book was released on 2003-10-24 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: The production of proteins in mammalian cells is an important tool in numerous scientific and commercial areas. For example, proteins for human therapy, vaccination or diagnostic applications are typically produced in mammalian cells. Gene cloning, protein engineering, biochemical and biophysical characterization of proteins also require the use of gene expression in mammalian cells. Other applications in widespread use involve screening of libraries of chemical compounds in drug discovery, and the development of cell-based biosensors.This book presents a state-of-the-art comprehensive coverage of the technical aspects of gene expression in mammalian cells, written by experienced scientists working at the forefront of the field.
Author : Liselotte Plesner
Publisher : Springer Science & Business Media
ISBN 13 : 1461559553
Total Pages : 286 pages
Book Rating : 4.4/5 (615 download)
Download or read book Ecto-ATPases written by Liselotte Plesner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the First International Workshop held in Mar de Plata, Argentina, August 26-30, 1996
Author : Mahira Parveen
Publisher : IOS Press
ISBN 13 : 9781586035082
Total Pages : 248 pages
Book Rating : 4.0/5 (35 download)
Download or read book Recent Trends in the Acetylcholinesterase System written by Mahira Parveen and published by IOS Press. This book was released on 2005 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enzyme acetylcholinesterase (AChE) has drawn the attention of scientist as it has played a striking role in Alzheimer's disease, Cardiac diseases and other diseases. A good discussion and overview document on AChE enzyme and its various aspects was felt lacking since a long time in the field of enzyme biochemistry as well as enzyme biotechnology and this publication fills this gap. Before this publication there was no data available on AChE enzyme inhibition, its kinetics, its peripheral sites, their role in catalytic and noncholinergic function of enzyme, ACh receptors, AChE and BuChE genes etc. All these topics together form a good basis for researchers and post graduate students in this field of interest. This book is a collection of recent advanced reports and data on AChE enzyme.
Author : Meir Shinitzky
Publisher : John Wiley & Sons
ISBN 13 : 3527616101
Total Pages : 390 pages
Book Rating : 4.5/5 (276 download)
Download or read book Biomembranes, Structural and Functional Aspects written by Meir Shinitzky and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to date review of basic research on biomembranes. In thisvolume, foremost experts in the field consider the most importantstructural and functional aspects of biomembranes: - MembraneLipids and Aging - Membrane-bound Enzymes - Ion Channels in Biological Membranes - Anion Exchangers of Mammalian Cell Membranes - Diversity of Transport Mechanisms in Bacteria. The volume is an excellent supplement to 'Biomembranes - PhysicalAspects', also edited by Meir Shinitzky. Together these booksprovide a comprehensive ground for understanding complexphysiological processes. Meir Shinitzky, Ph.D., is a Professor of Biophysics in theDepartment of Membrane Research and Biophysics, The WeizmannInstitute of Science, Rehovot, Israel. Since 1971, his research hasfocused on various aspects of membrane structure and dynamics.Currently his main interest is in manipulation of membrane fluidityfor clinical diagnoses and treatments. He has published extensivelyand is acknowledged worldwide as one of the leading experts in theincreasingly significant field of biomembrane research.
Author : B. Krisch
Publisher : Birkhäuser
ISBN 13 : 3034890109
Total Pages : 358 pages
Book Rating : 4.0/5 (348 download)
Download or read book The Peptidergic Neuron written by B. Krisch and published by Birkhäuser. This book was released on 2012-12-06 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropeptides rank among the phylogenetically oldest interneuronal signal substances. In the concept of neuro-secretion they were identified as neurohormones by which - via the blood - the brain regulates peripheral functions. It is now evident that the neuropeptides act as neurotransmitters/-modulators, as (neuro-)hormones, and paracrine or autocrine signal substances in diverse parts of the body. This book reviews, in several comprehensive articles written by distinguished specialists, the state of the art in the field of neuropeptides and peptidergic neurons. Special topics concern molecular aspects of processing, release and degradation of neuropeptides, receptors and signal transduction, comparative and behavioural aspects, and immunoregulatory effects of neuropeptides and their involvement on pathology of the central nervous system.
Author : Naoyuki Taniguchi
Publisher : Elsevier
ISBN 13 : 0323149626
Total Pages : 458 pages
Book Rating : 4.3/5 (231 download)
Download or read book Glutathione Centennial written by Naoyuki Taniguchi and published by Elsevier. This book was released on 2012-12-02 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glutathione Centennial: Molecular Perspectives and Clinical Implications is a collection of papers presented at the international symposium by the same titles, held in Osaka, Japan on December 1-4, 1988. This symposium concentrates on the developments is glutathione field, especially those related to molecular and clinical problems. This book is organized into five parts encompassing 30 chapters. Part I deals with the metabolic regulation, thermodynamic and kinetic properties, and enzyme regulation of glutathione. Part II examines the gene expression and molecular mechanism of glutathione-related enzymes, while Part III explores the association between carcinogenesis, xenobiotic compounds, and glutathione. Part IV highlights the clinical implications of glutathione, particularly its effect on vasospasm in subarachnoid hemorrhage and experimental hepatitis. Part V discusses the mechanism and regulation of biological transport of glutathione. This book will be of great value to glutathione enthusiasts and to many scientists in the brad fields of biology and medicine, and to their students.
Author : Bernard Testa
Publisher : Elsevier
ISBN 13 : 1483266893
Total Pages : 216 pages
Book Rating : 4.4/5 (832 download)
Download or read book Advances in Drug Research written by Bernard Testa and published by Elsevier. This book was released on 2013-10-22 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Drug Research, Volume 22 focuses on the concepts and facts of drug research. This book is divided into four chapters. Chapter 1 discusses the use of atomic properties and atom-centered indices in QSAR models, while Chapter 2 describes the pharmacokinetics of peptides and proteins. The nuclear receptors, emphasizing the aspects of molecular and genomic pharmacology are elaborated in Chapter 3. The last chapter covers the medicinal chemistry of a vast group of agents acting on nuclear receptors. This publication is valuable to drug researchers and students interested in advances in drugs.
Author : Derek Horton
Publisher : Gulf Professional Publishing
ISBN 13 : 9780120072552
Total Pages : 400 pages
Book Rating : 4.0/5 (725 download)
Download or read book Advances in Carbohydrate Chemistry and Biochemistry written by Derek Horton and published by Gulf Professional Publishing. This book was released on 2000-01-24 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.
Author : Janice E. Chambers
Publisher : Elsevier
ISBN 13 : 0080917267
Total Pages : 462 pages
Book Rating : 4.0/5 (89 download)
Download or read book Organophosphates Chemistry, Fate, and Effects written by Janice E. Chambers and published by Elsevier. This book was released on 2013-10-22 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity. Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds Examines organophosphorus compound-induced toxicity mediated by mechanisms other than inhibition of acetylcholinesterase Covers new research on differences in toxicity induced by the variety of organophosphorus Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo
Author : James McCubbin
Publisher : Academic Press
ISBN 13 : 032314800X
Total Pages : 502 pages
Book Rating : 4.3/5 (231 download)
Download or read book Stress, Neuropeptides, and systemic disease written by James McCubbin and published by Academic Press. This book was released on 2012-12-02 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress, Neuropeptides, and Systemic Disease traces the development of the neuropeptide hypothesis from its anatomical substrate to its functional correlates in animal and pre-clinical human models of stress-induced disease. The book contains articles that discuss the different aspects and findings on the study of neuropeptides such as the histochemical localization of peptide-containing cells and peptidergic receptors; the current concepts in hypothalamo-pituitary-adrenal axis regulation; neuropeptides involved in stress and their distribution in the mammalian central nervous system; and neuropeptide-mediated regulation of the neuroendocrine and autonomic responses to stress. The methods of measuring neuropeptides and their metabolism; stress responses and the pathogenesis of arthritis; brain peptides and gastrointestinal transit; and diminished opioid inhibition of blood pressure and pituitary function in hypertension development are presented as well. Physicians, neurobiologists, pharmacologists, and biological scientists will find the book very interesting.
