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Book Synopsis Malaria chemoprevention: preferred product characteristics by : World Health Organization
Download or read book Malaria chemoprevention: preferred product characteristics written by World Health Organization and published by World Health Organization. This book was released on 2023-04-20 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preferred product characteristics” (PPCs) are key tools to incentivize and guide the development of urgently needed health products. The PPCs published here aim to articulate the public health need, preferred characteristics, and clinical development considerations for drugs for malaria chemoprevention. WHO recommends several chemoprevention strategies for malaria control, including seasonal malaria chemoprevention, perennial malaria chemoprevention, intermittent preventive treatment of malaria in pregnancy, and mass drug administration. These strategies face a number of challenges such as suboptimal adherence and coverage and the emergence and spread of drug resistance. This document presents PPCs for the development of drugs for malaria chemoprevention in children, in pregnancy and in non-immune travellers, and outlines potential clinical development approaches, including the repurposing of approved malaria treatments for use as chemoprevention, recombining approved individual drugs into new combinations for malaria prevention, and the development of new drug combinations specifically for chemoprevention.
Book Synopsis WHO technical consultation on preferred product characteristics for drugs used in malaria chemoprevention by : World Health Organization
Download or read book WHO technical consultation on preferred product characteristics for drugs used in malaria chemoprevention written by World Health Organization and published by World Health Organization. This book was released on 2022-10-14 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Malaria vaccines: preferred product characteristics and clinical development considerations by : World Health Organization
Download or read book Malaria vaccines: preferred product characteristics and clinical development considerations written by World Health Organization and published by World Health Organization. This book was released on 2022-09-30 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preferred product characteristics” (PPCs) are key tools to incentivize and guide the development of urgently needed health products. The PPCs published here aim to articulate the public health need, preferred characteristics, and clinical development considerations for new malaria vaccines. WHO PPCs were initially conceived in 2012-2013 as a class of research-oriented normative guidance documents. The first edition of the WHO PPCs for malaria vaccines (WHO/IVB/14.09), published in 2014, was the first-in-class of these documents. The document published here is an update to the 2014 edition. Since the first malaria vaccine PPCs were published in 2014, major milestones in malaria vaccine R&D have been achieved. In 2021, RTS,S/AS01 became the first malaria vaccine to be recommended by WHO for use in moderate- to high-transmission settings in sub-Saharan Africa. However, a healthy market of vaccines will be needed to meet the global demand. A continued focus on developing new and improved vaccines will be vital in our efforts to reduce global malaria burden and to achieve elimination and eradication. This includes malaria vaccines to prevent blood-stage infection, reduce morbidity and mortality, and/or reduce community-level transmission.
Book Synopsis WHO meeting on preferred product characteristics for monoclonal antibodies for malaria prevention by : World Health Organization
Download or read book WHO meeting on preferred product characteristics for monoclonal antibodies for malaria prevention written by World Health Organization and published by World Health Organization. This book was released on 2022-10-21 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Monoclonal antibodies for malaria prevention: preferred product characteristics and clinical development considerations by : World Health Organization
Download or read book Monoclonal antibodies for malaria prevention: preferred product characteristics and clinical development considerations written by World Health Organization and published by World Health Organization. This book was released on 2023-04-20 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preferred product characteristics (PPCs) are key tools to incentivize and guide the development of urgently needed health products. The PPCs published here aim to articulate the public health need, preferred characteristics, and clinical development considerations for monoclonal antibodies (mAbs) for malaria prevention. Alongside the development of new malaria vaccines and chemoprevention drugs, there have been recent R&D advances in the development of mAbs for malaria prevention. Passive immunization with mAbs through direct administration of functional antibodies could potentially overcome some of the limitations of vaccines by providing immediate protection. Furthermore, mAbs with simplified dose regimens could potentially circumvent some of the coverage and adherence issues faced by malaria chemoprevention. To support this quickly developing R&D area, WHO convened a scientific development group to consider the PPCs for mAbs to be used for malaria prevention, with a focus on the reduction of morbidity and mortality in infants and children due to Plasmodium falciparum.
Book Synopsis Malaria vaccine advisory committee (MALVAC) meeting on preferred product characteristics for malaria vaccines by :
Download or read book Malaria vaccine advisory committee (MALVAC) meeting on preferred product characteristics for malaria vaccines written by and published by World Health Organization. This book was released on 2022-02-10 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt: On 27–28 October 2020, the WHO Initiative for Vaccine Research and Global Malaria Programme convened a meeting of the Malaria Vaccine Advisory Committee (MALVAC) to review priority issues in product development in malaria vaccine research and development (R&D). Experts reviewed major use case scenarios for malaria vaccines, including the reduction of morbidity and mortality, and the reduction of malaria transmission. Other potential use case scenarios were also discussed, including seasonal vaccination, vaccination to prevent malaria in pregnancy, and vaccines targeting non-Plasmodium falciparum species such as P. vivax. MALVAC members discussed how best to update and build on the previously developed malaria vaccine Preferred Product Characteristics (PPCs), bearing in mind advances in the field and lessons learned from the development and evaluation of the RTS,S/AS01E vaccine.
Book Synopsis World malaria report 2022 by : World Health Organization
Download or read book World malaria report 2022 written by World Health Organization and published by World Health Organization. This book was released on 2022-12-08 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year, WHO’s World malaria report offers in-depth information on the latest trends in malaria control and elimination at global, regional and country levels. The report highlights progress towards global targets and describes opportunities and challenges for curbing and eliminating the disease. This year’s report includes three new sections on: (1) global and regional initiatives launched in 2021 and 2022; (2) global malaria surveillance and country-level case studies on surveillance systems assessments; and (3) research and development. The report also includes an expanded section on threats to malaria control, with a focus on the declining effectiveness of insecticide-treated mosquito nets.
Book Synopsis WHO Malaria Policy Advisory Group (MPAG) meeting report, 18–20 April 2023 by : World Health Organization
Download or read book WHO Malaria Policy Advisory Group (MPAG) meeting report, 18–20 April 2023 written by World Health Organization and published by World Health Organization. This book was released on 2023-06-01 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt: On 18–20 April 2023, the WHO Malaria Policy Advisory Group (MPAG) convened to review updates and progress, and to provide guidance on thematic areas of work by the Global Malaria Programme. The meeting focused on the following topics: 1) the RBM Partnership to End Malaria evaluation of the “High burden to high impact” (HBHI) approach; 2) updates on the vector control, treatment and diagnostic recommendations in the WHO guidelines for malaria; 3) revisiting comparative effectiveness in the context of the arrival of new vector control products; 4) an update on certification of malaria elimination and the E-2025 Global Forum; 5) an update on the RTS,S/AS01 Malaria Vaccine Implementation Programme and WHO evidence review for the R21/Matrix-M vaccine; 6) an update on the work areas of the Strategic Information for Response Unit; 7) a report from the technical consultation on the effectiveness of rectal artesunate (RAS) and field implementation manual; 8) a report from the technical consultation on community-based delivery of intermittent preventive treatment of malaria in pregnancy (IPTp); 9) an update on the WHO/TDR field implementation manual for seasonal malaria chemoprevention (SMC); 10) an update on the Anopheles stephensi regional strategy; 11) an update on histidine-rich protein 2 (HRP2) gene deletions and global response plan; and 12) an update on antimalarial drug resistance in Africa.
Book Synopsis Endectocide and ectocide products for malaria transmission control by : World Health Organization
Download or read book Endectocide and ectocide products for malaria transmission control written by World Health Organization and published by World Health Organization. This book was released on 2022-06-30 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Saving Lives, Buying Time by : Institute of Medicine
Download or read book Saving Lives, Buying Time written by Institute of Medicine and published by National Academies Press. This book was released on 2004-09-09 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.
Book Synopsis Malaria Policy Advisory Group (MPAG) meeting, October 2021 by :
Download or read book Malaria Policy Advisory Group (MPAG) meeting, October 2021 written by and published by World Health Organization. This book was released on 2021-11-08 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: On 4–7 October 2021, the WHO Malaria Policy Advisory Group (MPAG) convened virtually to review updates and progress, and to provide guidance on thematic areas of work by the Global Malaria Programme. The meeting focused on 8 topics in 5 open sessions: 1) “Rethinking Malaria”; 2) update on the technical consultation on non-inferiority evaluations of vector control tools; 3) a discussion on malaria re-bound; 4) an update on antimalarial drug resistance in Africa; 5) an update on rectal artesunate (RAS) and quality of care; 6) a review of the relationship between chemoprevention and drug resistance; 7) an update on the WHO guidelines for malaria; and 8) a joint session with the Strategic Advisory Group of Experts on Immunization (SAGE) to review the evidence and consider a recommendation for broader use of the malaria vaccine.
Author :Centers for Disease Control and Prevention CDC Publisher :Oxford University Press ISBN 13 :0190628634 Total Pages :705 pages Book Rating :4.1/5 (96 download)
Book Synopsis CDC Yellow Book 2018: Health Information for International Travel by : Centers for Disease Control and Prevention CDC
Download or read book CDC Yellow Book 2018: Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.
Book Synopsis Malaria Policy Advisory Group (MPAG) meeting, April 2021 by :
Download or read book Malaria Policy Advisory Group (MPAG) meeting, April 2021 written by and published by World Health Organization. This book was released on 2021-05-21 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis WHO Malaria Policy Advisory Group (MPAG) meeting, October 2022 by : World Health Organization
Download or read book WHO Malaria Policy Advisory Group (MPAG) meeting, October 2022 written by World Health Organization and published by World Health Organization. This book was released on 2022-11-30 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis WHO Malaria Policy Advisory Group (MPAG) meeting, December 2020 by :
Download or read book WHO Malaria Policy Advisory Group (MPAG) meeting, December 2020 written by and published by World Health Organization. This book was released on 2020-12-23 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Global Malaria Programme operational strategy 2024-2030 by : World Health Organization
Download or read book Global Malaria Programme operational strategy 2024-2030 written by World Health Organization and published by World Health Organization. This book was released on 2024-04-16 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: As WHO's technical department for malaria, the Global Malaria Programme has an important role to play in leading the global response against this disease. Through its direct actions and network, it has the potential to shape the malaria ecosystem and achieve impact at country level. With this in mind, the Global Malaria Programme has developed an operational strategy outlining its priorities for the period 2024‒2030 and the 4 strategic levers to control and eliminate malaria that are decisively within the Programme’s mandate: norms and standards, new tools and innovation, strategic information for impact, and leadership. The strategy describes how the Global Malaria Programme will also transform by collaborating more effectively with other programmes, regional and country offices and partners, guided by lessons learned from WHO’s Thirteenth General Programme of Work (GPW13) and the GPW14 priorities.
Book Synopsis Guidelines for the Treatment of Malaria. Third Edition by : World Health Organization
Download or read book Guidelines for the Treatment of Malaria. Third Edition written by World Health Organization and published by World Health Organization. This book was released on 2015-08-13 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria remains an important cause of illness and death in children and adults in countries in which it is endemic. Malaria control requires an integrated approach including prevention (primarily vector control) and prompt treatment with effective antimalarial agents. Malaria case management consisting of prompt diagnosis and effective treatment remains a vital component of malaria control and elimination strategies. Since the publication of the first edition of the Guidelines for the treatment of malaria in 2006 and the second edition in 2010 all countries in which P. falciparum malaria is endemic have progressively updated their treatment policy from use of ineffective monotherapy to the currently recommended artemisinin-based combination therapies (ACT). This has contributed substantially to current reductions in global morbidity and mortality from malaria. Unfortunately resistance to artemisinins has arisen recently in P. falciparum in South-East Asia which threatens these gains. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on a firmer evidence base for most antimalarial drugs and in addition include recommendation on the use of drugs to prevent malaria in groups at high risk. The Guidelines provide a framework for designing specific detailed national treatment protocols taking into account local patterns of resistance to antimalarial drugs and health service capacity. It provides recommendations on treatment of uncomplicated and severe malaria in all age groups all endemic areas in special populations and several complex situations. In addition on the use of antimalarial drugs as preventive therapy in healthy people living in malaria-endemic areas who are high risk in order to reduce morbidity and mortality from malaria. The Guidelines are designed primarily for policy-makers in ministries of health who formulate country-specific treatment guidelines. Other groups that may find them useful include health professionals and public health and policy specialists that are partners in health or malaria control and the pharmaceutical industry. The treatment recommendations in the main document are brief; for those who wish to study the evidence base in more detail a series of annexes is provided with references to the appropriate sections of the main document.
