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Local Antibiotic Delivery Systems For The Treatment Of Osteomyelitis
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Book Synopsis Technological Challenges in Antibiotic Discovery and Development by : National Research Council
Download or read book Technological Challenges in Antibiotic Discovery and Development written by National Research Council and published by National Academies Press. This book was released on 2014-01-27 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable in September 2013 to explore the current state of antibiotic discovery and examine the technology available to facilitate development. Through formal presentations and panel discussions, participants from academia, industry, federal research agencies discussed the technical challenges present and the incentives and disincentives industry faces in antibiotic development, and identified novel approaches to antibiotic discovery. Antibiotic resistance is a serious and growing problem in modern medicine and it is emerging as a pre-eminent public health threat. Each year in the United States alone, at least two million acquire serious infections with bacteria that are resistant to one or more antibiotics, and at least 23,000 people die annually as a direct result of these antibiotic-resistant infections. In addition to the toll on human life, antibiotic-resistant infections add considerable and avoidable costs to the already overburdened U.S. health care system. This report explores the challenges in overcoming antibiotic resistance, screening for new antibiotics, and delivering them to the sites of infection in the body. The report also discusses a path forward to develop the next generation of potent antimicrobial compounds capable of once again tilting the battle against microbial pathogens in favor of humans. Technological Challenges in Antibiotic Discovery and Development gives a broad view of the landscape of antibiotic development and the technological challenges and barriers to be overcome.
Book Synopsis Bone and Joint Infections by : W. Zimmerli
Download or read book Bone and Joint Infections written by W. Zimmerli and published by John Wiley & Sons. This book was released on 2015-01-27 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infections of the bones (osteomyelitis) and joints (septic arthritis) are serious health problems which require antibiotics and often surgery. Awareness among health professionals of the causes and treatment options for various types of bone and joint infections is essential for effective resolution. Bone and Joint Infections takes a multidisciplinary approach in covering the diagnostic and therapeutic treatment of osteomyelitis and septic arthritis, including different types of implant-associated infections. Correct and rapid diagnosis of bone and joint infection is crucial, and requires the input of a variety of specialists. Bone and Joint Infection takes a similarly collaborative and comprehensive approach, including chapters authored by clinicians, laboratory specialists, and surgeons. Covering the basic microbiology and clinical aspects of bone and joint infection, this book will be a valuable resource both for researchers in the lab and for physicians and surgeons seeking a comprehensive reference on osteomyelitis and septic arthritis.
Book Synopsis Cutting-Edge Enabling Technologies for Regenerative Medicine by : Heung Jae Chun
Download or read book Cutting-Edge Enabling Technologies for Regenerative Medicine written by Heung Jae Chun and published by Springer. This book was released on 2018-10-24 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in depth the latest enabling technologies for regenerative medicine. The opening section examines advances in 3D bioprinting and the fabrication of electrospun and electrosprayed scaffolds. The potential applications of intelligent nanocomposites are then considered, covering, for example, graphene-based nanocomposites, intrinsically conductive polymer nanocomposites, and smart diagnostic contact lens systems. The third section is devoted to various drug delivery systems and strategies for regenerative medicine. Finally, a wide range of future enabling technologies are discussed. Examples include temperature-responsive cell culture surfaces, nanopatterned scaffolds for neural tissue engineering, and process system engineering methodologies for application in tissue development. This is one of two books to be based on contributions from leading experts that were delivered at the 2018 Asia University Symposium on Biomedical Engineering in Seoul, Korea – the companion book examines in depth novel biomaterials for regenerative medicine.
Book Synopsis Gentamicin-PMMA Beads by : Gerardus Hermanus Ignatius Maria Walenkamp
Download or read book Gentamicin-PMMA Beads written by Gerardus Hermanus Ignatius Maria Walenkamp and published by . This book was released on 1983 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Orthopedic Infection by : David Schlossberg
Download or read book Orthopedic Infection written by David Schlossberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, clinically oriented reference details the state-of-the-art approach to infections of bones and joints. Utility for all practitioners is ensured by the wide range of contributors who include infectious disease specialists, rheumatologists, orthopedic surgeons, and radiologists. This is the definitive resource for the clinician who treats orthopedic infections.
Book Synopsis Essentials of Cemented Knee Arthroplasty by : Erik Hansen
Download or read book Essentials of Cemented Knee Arthroplasty written by Erik Hansen and published by Springer Nature. This book was released on 2021-12-30 with total page 771 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Editors of “Essentials of Cemented Knee Arthroplasty” have compiled a comprehensive textbook on what many consider the most successful surgical procedure of the century. This book rounds out the compendium previously published by Springer on arthroplasty related topics: “The Well Cemented Total Hip Arthroplasty”, “PMMA Cements”, and “Management of Periprosthetic Joint Infection”. Unique to this text is the high quality contributions from over 160 world wide experts in the field, and provides a unique international perspective on the multifaceted topic of knee replacement surgery. Sections include a focus on Surgical Indications, Implant Design, Novel Technologies, Complications, and Cementing Technique, amongst others. Each Chapter not only draws on the most current literature on the subject, but also crystalizes the most important points into clinically relevant, practically applicable “take home messages”. This singular text is notable for not only its breadth, but also its depth, and will be an invaluable resource for knee arthroplasty surgeons throughout the globe.
Book Synopsis Handbook of Bioceramics and Biocomposites by : Iulian Vasile Antoniac
Download or read book Handbook of Bioceramics and Biocomposites written by Iulian Vasile Antoniac and published by Springer. This book was released on 2016-05-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook describes several current trends in the development of bioceramics and biocomposites for clinical use in the repair, remodelling, and regeneration of bone tissue. Comprehensive coverage of these materials allows fundamental aspects of the science and engineering to be seen in close relation to the clinical performance of dental and orthopaedic implants. Bioceramics and biocomposites appear to be the most dynamic area of materials development for both tissue engineering and implantable medical devices. Almost all medical specialties will continue to benefit from these developments, but especially dentistry and orthopaedics. In this Handbook, leading researchers describe the use of bionanomaterials to create new functionalities when interfaced with biological molecules or structures. Also described are technologies for bioceramics and biocomposites processing in order to fabricate medical devices for clinical use. Another important section of the book is dedicated to tissue regeneration with development of new matrices. A targeted or personalized treatment device reduces drug consumption and treatment expenses, resulting in benefits to the patient and cost reductions for public health systems. This authoritative reference on the state-of-the-art in the development and use of bioceramics and biocomposites can also serve as the basis of instructional course lectures for audiences ranging from advanced undergraduate students to post-graduates in materials science and engineering and biomedical engineering.
Book Synopsis Oxford Textbook of Rheumatology by : Philip Conaghan
Download or read book Oxford Textbook of Rheumatology written by Philip Conaghan and published by Oxford University Press. This book was released on 2013-10 with total page 1553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.
Book Synopsis Oral Cephalosporins by : Robert C. Moellering
Download or read book Oral Cephalosporins written by Robert C. Moellering and published by S Karger Ag. This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an excellent survey of the chemistry, microbiology, pharmacology and clinical use of the oral cephalosporins in general and the newer agents in particular. The cephalosporins have long provided satisfactory treatment for many disorders without causing serious side effects; and over the past fifty years forms with different antimicrobial, pharmacologic and toxicologic properties have been developed. Despite the broad spectrum of their activity against a large variety of gram-positive and gram-negative bacteria, the third-generation oral cephalosporins including the prodrug esters do not work against Pseudomonas aeruginosa, methicillin-resistant staphylococci, enterococci or Bacteroides species. Many, however, are suitable for treating infections of the respiratory and urinary tracts and of the skin and its structure, as well as certain sexually-transmitted diseases. Authors consider other possible uses, against multi-resistant Enterobacteriaceae for instance, but also point out the limitations of the oral cephalosporins. For those working in the fields of infectious disease, bacteriology, chemotherapy, pharmaceutics and pharmacokinetics, this book is a valuable source of authoritative information.
Download or read book Antimicrobial Therapy I written by and published by . This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment by : Jorge Coelho
Download or read book Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment written by Jorge Coelho and published by Springer Science & Business Media. This book was released on 2013-03-15 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.
Book Synopsis Equine Fracture Repair by : Alan J. Nixon
Download or read book Equine Fracture Repair written by Alan J. Nixon and published by John Wiley & Sons. This book was released on 2020-01-09 with total page 933 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a long-awaited Second Edition of this comprehensive, state-of-the-art reference for fracture repair in horses The Second Edition of Equine Fracture Repair has been thoroughly revised and updated to present the most current information on fracture repair in horses. Written to be accessible, the text is logically arranged, presenting the most authoritative information on equine fracture repair with explanations of the expected outcomes. The book provides valuable insight as to whether a fracture should be repaired, the degree of difficulty of the procedure, and a wealth of practical information on surgical techniques. This fully revised Second Edition offers a valuable tool for veterinarians making clinical decisions when faced with horse fractures, covering emergency care and splinting, the most current innovative techniques in equine fracture repair, and new implant systems. With contributions from leading experts in the field, the revised edition continues to be the essential reference to the subject. This essential resource: Offers a revised edition of the most comprehensive reference on the repair of fracture in horses, with complete information on patient assessment, emergency splinting and casting, and guidance in treatment choices Includes contributions from leading experts in the field Presents information organized by fracture type for quick access Provides valuable outcome assessment with helpful discussions of the degree of difficulty to aid in case management, incorporating information on the newest techniques and implant systems Concludes with extensive information on the identification and management of complications associated with fractures and repair methods This revised and updated edition of Equine Fracture Repair continues to provide a comprehensive resource for understanding the most effective and current techniques available for the treatment of fractures in horses.
Book Synopsis Pediatric Osteoarticular Infections by : Anil Agarwal
Download or read book Pediatric Osteoarticular Infections written by Anil Agarwal and published by JP Medical Ltd. This book was released on 2013-01-30 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise guide brings orthopaedic surgeons and paediatricians up to date with the latest developments in the management of bone and joint (osteoarticular) infections in children. Beginning with an introduction to the causes and development of osteoarticular disorders, the following chapters discuss their clinical features, laboratory diagnosis and treatment options, both surgical and conservative. Each chapter describes a different infection and its management, with a separate chapter examining drug-resistant osteoarticular tuberculosis and co-infection with HIV. The final section discusses advances and research in the condition. Key points Concise guide to the diagnosis and management of bone and joint infections in children Each chapter discusses a different infection and covers conservative and surgical treatment Final chapter describes new advances and research Includes more than 150 full colour images and illustrations
Book Synopsis Primary Knee Arthroplasty by : Urs Munzinger
Download or read book Primary Knee Arthroplasty written by Urs Munzinger and published by Springer. This book was released on 2011-06-28 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primary knee arthroplasty (PKA) has a long history and modern mobile bearing knee implants are successfully implanted worldwide since 1977. Primary Knee Arthroplasty focuses on basic science, personal surgical experiences, clinical, functional and radiographic outcomes of PKA, with special focus on challenging knees such as severe varus and valgus deformities with associated bone defects, fixed flexion deformities, soft tissue contractures, and arthrodesed knees. Patella treatment with or without resurfacing is addressed in great detail. Early criterion-based rehabilitation and the patient’s return to participating in sports are discussed as is the management of prosthetic or surgery related complications. Lavishly illustrated to complement the text, Primary Knee Arthroplasty is a ‘must-have’ for all practicing knee replacement surgeons, orthopedic surgeons in training, orthopedic nurses, and physiotherapists with a special interest in knee arthroplasty. Tips and tricks provided by experienced knee surgeons are indispensable for daily clinical practice.
Book Synopsis Antimicrobial Chemotherapy by : Roger Finch
Download or read book Antimicrobial Chemotherapy written by Roger Finch and published by OUP Oxford. This book was released on 2012-01-05 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.
Book Synopsis Management of Periprosthetic Joint Infections (PJIs) by : J.J. Chris Arts
Download or read book Management of Periprosthetic Joint Infections (PJIs) written by J.J. Chris Arts and published by Woodhead Publishing. This book was released on 2016-10-25 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of Periprosthetic Joint Infections (PJIs): Management of PJIs discusses periprosthetic joint infection (PJI), a fairly rare occurrence that is nonetheless one of the most serious complications in joint replacement surgery. Intricate interactions between the pathogen, the host, and the implant can result in PJIs which are not only physically devastating for the patient, but also financially crippling for health authorities and insurance companies. Actions taken to minimize the risk of PJIs can be extremely challenging for the orthopaedic community. Consequently, new research, which is detailed in this comprehensive book, is being undertaken to minimize and manage these challenging infections. - Provides essential background knowledge on the mechanisms and identification of PJIs - Dedicated chapters focus on the complex, but vital eccentricities between PJIs in different areas of the body - Contains contributions from a mixture of clinical and academic experts in the field, thus ensuring balanced coverage
Book Synopsis Osteomyelitis of the Jaws by : Marc Baltensperger
Download or read book Osteomyelitis of the Jaws written by Marc Baltensperger and published by Springer Science & Business Media. This book was released on 2008-11-07 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Osteomyelitis of the Jaws” is the first textbook of its kind covering exclusively all aspects of this challenging disease. A clear classification of osteomyelitis of the jaws is provided. Clinical presentation and diagnosis are meticulously described and illustrated. Radiological imaging from conventional radiographs to CT, MRI and PET diagnosis are outlined for all types of osteomyelitis of the jaws. Pathology and Pathophysiology of this disease are described in a clear way. All therapeutic modalities from surgery to antibiotic and hyperbaric oxygen therapy are comprehensively outlined and discussed. Each type of Osteomyelitis of the jaws are additionally described and illustrated in case reports giving this book a very practical approach to the subject.
