Liver Regeneration and Carcinogenesis

Download Liver Regeneration and Carcinogenesis PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 9780080535548
Total Pages : 402 pages
Book Rating : 4.5/5 (355 download)

DOWNLOAD NOW!


Book Synopsis Liver Regeneration and Carcinogenesis by : Gerard Meurant

Download or read book Liver Regeneration and Carcinogenesis written by Gerard Meurant and published by Elsevier. This book was released on 1995-09-27 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level

Liver Regeneration

Download Liver Regeneration PDF Online Free

Author :
Publisher : John Libbey Eurotext
ISBN 13 : 9780861963478
Total Pages : 180 pages
Book Rating : 4.9/5 (634 download)

DOWNLOAD NOW!


Book Synopsis Liver Regeneration by : D. Bernuau

Download or read book Liver Regeneration written by D. Bernuau and published by John Libbey Eurotext. This book was released on 1992 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents an approach to the hepatic physiology and multiple developments about cellular biology such as cell cycle regulation, growth factors and oncogenes.

Liver Carcinogenesis

Download Liver Carcinogenesis PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642792154
Total Pages : 489 pages
Book Rating : 4.6/5 (427 download)

DOWNLOAD NOW!


Book Synopsis Liver Carcinogenesis by : George G. Skouteris

Download or read book Liver Carcinogenesis written by George G. Skouteris and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last years much attention has been given to the investigation of the roles of specific growth modulators acting on liver cell populations. HGF functions as a pleotropic factor in the liver as well as in other extrahepatic tissues. The hepatic stem cell compartment is thought to play a major role in liver tissue restoration. Mechanisms of cell growth and cell death of the liver are described in detail, with particular emphasis on apoptosis. The functions of HBV-pX protein and the roles of hepatitis B virus gene expression relation to hepatocellular carcinoma are discussed. Techniques for obtaining human and nonhuman hepatocytes and other liver cell types and for efficient transfer and expression of genes in hepatocytes and liver-derived cell lines are presented.

Normal and Malignant Liver Cell Growth

Download Normal and Malignant Liver Cell Growth PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387480
Total Pages : 268 pages
Book Rating : 4.3/5 (874 download)

DOWNLOAD NOW!


Book Synopsis Normal and Malignant Liver Cell Growth by : W.E. Fleig

Download or read book Normal and Malignant Liver Cell Growth written by W.E. Fleig and published by Springer Science & Business Media. This book was released on 1998-12-31 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although cell turnover in normal adult liver is extremely low, hepatic tissue is notorious for its almost infinite capacity to regenerate in cases of viral, toxic or traumatic damage. Hepatocellular carcinoma is one of the most frequent malignancies worldwide and causes more than a million deaths per year. The mechanisms governing normal proliferation and malignant transformation of liver cells are of utmost interest for the understanding of regeneration and hepatocarcinogenesis and for the development of new therapeutic strategies. Therefore, the International Falk Workshop held in Halle, Germany, on January 29-30 1998, focused on the issues of normal and malignant liver cell growth. Knowledge in this area of research has expanded rapidly during recent years. This book of proceedings summarizes the latest advances both in basic science and clinical research. Stimulating discussion set the basis for the development of new strategies in diagnosis and treatment of hepatocellular carcinoma and for the manipulation of regeneration in cases of acute or chronic loss of functional liver tissue.

The Liver

Download The Liver PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119436826
Total Pages : 1156 pages
Book Rating : 4.1/5 (194 download)

DOWNLOAD NOW!


Book Synopsis The Liver by : Irwin M. Arias

Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Liver Regeneration

Download Liver Regeneration PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128004312
Total Pages : 326 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!


Book Synopsis Liver Regeneration by : Udayan M. Apte

Download or read book Liver Regeneration written by Udayan M. Apte and published by Academic Press. This book was released on 2015-08-13 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications presents cutting-edge information on liver regeneration research through an integrated, systems-wide perspective. The book addresses discoveries on hepatic progenitor cells, liver regeneration after chemical damage, and liver regeneration as a prime therapy for liver failure and disease. By addressing the urgent need for translating basic research findings into clinically relevant modalities and potential therapeutic applications, the book provides the data needed to improve liver patient management. Hundreds of full-color, graphic photographs and illustrations underline key elements and show researchers and students important aspects of liver transplantation, immunofluorescence, and other techniques used in liver regeneration. Summarizes current liver regeneration studies and discussions on expected discoveries Provides an overview of standard scientific and cutting-edge technologies to study liver regeneration Presents details on the molecular mechanisms that affect liver regeneration Highly illustrated, with hundreds of full-color, graphic photographs and illustrations to enhance the learning process

Experimental Hepatocarcinogenesis

Download Experimental Hepatocarcinogenesis PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461309573
Total Pages : 305 pages
Book Rating : 4.4/5 (613 download)

DOWNLOAD NOW!


Book Synopsis Experimental Hepatocarcinogenesis by : M.B. Roberfroid

Download or read book Experimental Hepatocarcinogenesis written by M.B. Roberfroid and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: The meeting on experimental hepatocarcinogenesis which took place in Spa, Belgium at the end of May 1987 was the Second European Meeting. About 100 scientists, mostly from Europe but also from the United States, met there for three days in a very friendly atmosphere to exchange knowledge and ideas on experimental and human liver carcinogenesis. The main topics discussed during the meeting included general reviews on hepatocarcinogenesis, experimental models of hepa tocarcinogenesis, biology of hepatocarcinogenesis, and in vitro studies in hepatocarcinogenesis. They are all covered by the various chapters of this proceedings volume, which reflects the present state of knowledge in this important field of cancer research. The final aim of that research is to understand the basic mechanisms of carcinogenesis. The liver offers a parti cularly interesting tool to reach such a goal. Indeed, its biochemistry, its morphology, and its physiology are very diverse, but relatively well known. Various protocols have been developed to produce hepatocellular carcinomas or other malignant tumors. Their appearance is most often preceded by phenotypically altered foci and nodules which have been isolated and characterized. The major cell populations of normal, neoplastic, and malignant livers have been cultivated.

Liver Growth and Repair

Download Liver Growth and Repair PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9401149321
Total Pages : 681 pages
Book Rating : 4.4/5 (11 download)

DOWNLOAD NOW!


Book Synopsis Liver Growth and Repair by : A. Strain

Download or read book Liver Growth and Repair written by A. Strain and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nelson Fausto The Greek myth of Prometheus with its picture of a vulture feasting on its chained victimhas traditionallyprovided a visualimageofliverregeneration. Itis apowerful and frightening representationbut ifone were to substitute the vulture by a surgeon and Prometheus by a patient laying on a properly prepared operating table, the outcomeoftheprocedurewould not differ significantlyfrom that describedbyGreek poets. Yet few of us who work in the field have stopped long enough to ask where this myth originated. Did the poet observe a case of liver regeneration in a human being? Was it brilliant intuition or perhaps, literally, just a 'gut feeling' of a poet looking for good rhymes that led to the prediction that livers grow when part of the tissueisremoved? Thisbookdoesnotattemptto solve these historical issues. Itdoes, instead, cover in detail some of the major modem themes of research on liver regen eration, injury and repair. As indicated in Dr. N. Bucher's chapter, the modem phase ofexperimental studies on liver regeneration started in 1931 with the publication by Higgins and Anderson of a method to perform a two-thirds resection of the liver of a rat. The technique described has 3 remarkable features: 1) it is highly reproducible, resulting in the removal of 68% of the liver, 2) it has minimal if any mortality, and 3) it consists only of blood vessel ligation and does not involve cutting through or wounding hepatic tissue.

Stem Cells and Cancer in Hepatology

Download Stem Cells and Cancer in Hepatology PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128123028
Total Pages : 382 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!


Book Synopsis Stem Cells and Cancer in Hepatology by : Yun-Wen Zheng

Download or read book Stem Cells and Cancer in Hepatology written by Yun-Wen Zheng and published by Academic Press. This book was released on 2018-05-18 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells and Cancer in Hepatology: From the Essentials to Application offers basic scientists and clinicians in the fields of stem cells, hepatology and oncology an overview of the interaction between liver biology, stem cells and cancer. It discusses how the liver performs regeneration and repair, the role stem cells play in these processes, and the mechanisms by which liver cancers are initiated and developed. As the field of stem cells and cancer stem cells in hepatology is new and dynamic, thus making it difficult for researchers and clinicians to understand the most relevant historic and novel studies, this volume addresses that challenge. Addresses both the basic and clinical perspectives of the topic, including sections on normal and cancer stem cells of the liver Provides coverage of the molecular mechanisms of liver development, the proliferation of hepatic progenitor cells during development, epithelial cell plasticity, generation of hepatocytes by transdifferentiation, liver tissue engineering, and more Presents a study of hepatic stem cells that will help readers understand critical events during development, stem cell differentiation towards functional liver cell fate, and tumor initiation

Liver Regeneration

Download Liver Regeneration PDF Online Free

Author :
Publisher : Mss Information Corporation
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Liver Regeneration by : Leonard I. Malkin

Download or read book Liver Regeneration written by Leonard I. Malkin and published by Mss Information Corporation. This book was released on 1973 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Regeneration of Liver and Kidney

Download Regeneration of Liver and Kidney PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 314 pages
Book Rating : 4.:/5 (37 download)

DOWNLOAD NOW!


Book Synopsis Regeneration of Liver and Kidney by : Nancy L. R. Bucher

Download or read book Regeneration of Liver and Kidney written by Nancy L. R. Bucher and published by . This book was released on 1971 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Influence of Radiation Therapies on Liver Cancer

Download Influence of Radiation Therapies on Liver Cancer PDF Online Free

Author :
Publisher : Frontiers Media SA
ISBN 13 : 283250292X
Total Pages : 155 pages
Book Rating : 4.8/5 (325 download)

DOWNLOAD NOW!


Book Synopsis Influence of Radiation Therapies on Liver Cancer by : John Varlotto

Download or read book Influence of Radiation Therapies on Liver Cancer written by John Varlotto and published by Frontiers Media SA. This book was released on 2022-10-19 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hepatocellular Carcinoma

Download Hepatocellular Carcinoma PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3030215407
Total Pages : 366 pages
Book Rating : 4.0/5 (32 download)

DOWNLOAD NOW!


Book Synopsis Hepatocellular Carcinoma by : Yujin Hoshida

Download or read book Hepatocellular Carcinoma written by Yujin Hoshida and published by Springer. This book was released on 2019-08-05 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.

Polyploidization and Cancer

Download Polyploidization and Cancer PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441961992
Total Pages : 157 pages
Book Rating : 4.4/5 (419 download)

DOWNLOAD NOW!


Book Synopsis Polyploidization and Cancer by : Randy Y.C. Poon

Download or read book Polyploidization and Cancer written by Randy Y.C. Poon and published by Springer Science & Business Media. This book was released on 2011-01-11 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overview subjects relating to polyploidization and cancer.

Liver Carcinogenesis

Download Liver Carcinogenesis PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 432 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Liver Carcinogenesis by :

Download or read book Liver Carcinogenesis written by and published by . This book was released on 1979 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cooperation of Liver Cells in Health and Disease

Download Cooperation of Liver Cells in Health and Disease PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642565530
Total Pages : 154 pages
Book Rating : 4.6/5 (425 download)

DOWNLOAD NOW!


Book Synopsis Cooperation of Liver Cells in Health and Disease by : Z. Kmiec

Download or read book Cooperation of Liver Cells in Health and Disease written by Z. Kmiec and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.

Tumors of the Liver

Download Tumors of the Liver PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642487300
Total Pages : 318 pages
Book Rating : 4.6/5 (424 download)

DOWNLOAD NOW!


Book Synopsis Tumors of the Liver by : G. T. Pack

Download or read book Tumors of the Liver written by G. T. Pack and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: The surgical resection of a major portion of the liver for cancer of this viscus has long been neglected. Although the first successful resection of a primary malignant tumor of the liver was performed by LUCKE in 1891, this pioneer effort failed to stimulate interest in the operative removal of hepatic neoplasms. Earlier surgeons were intimidated by the concept of the liver as a huge vascular sponge possessed of three intricate circulatory systems. To the fear of uncontrollable hemorrhage was added the supposed hazard of hepatic insufficiency following the removal of a large portion of an organ with so many vital functions. Last but not least was the difficulty in surgical exposure. Only in recent years has the sporadic interest of surgeons been changed to a growing concern about the possibilities of extirpation of hepatic tumors by the per formance of major hepatic lobectomies. Four factors have contributed to this: 1) the dissemination of more accurate information about the surgical anatomy of the intrin sic and extrinsic hepatic circulatory systems, which has acquainted surgeons with the principles and techniques of hemostasis essential for successful operative intervention on the liver; 2) increased knowledge of the functions and regenerative capacity of the liver; 3) greater diagnostic skill aided by modern laboratory procedures; 4) improved surgical exposure of the liver by the use of laparothoracotomy incisions. Primary liver cancer varies widely in incidence in different parts of the world.