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Author : G. Galli
Publisher : Springer Science & Business Media
ISBN 13 : 1461594278
Total Pages : 257 pages
Book Rating : 4.4/5 (615 download)
Download or read book Liver, Nutrition, and Bile Acids written by G. Galli and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Springer
Publisher :
ISBN 13 : 9781461594284
Total Pages : 272 pages
Book Rating : 4.5/5 (942 download)
Download or read book Liver, Nutrition, and Bile Acids written by Springer and published by . This book was released on 2014-01-15 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : G. Galli
Publisher : Springer
ISBN 13 : 9781461594291
Total Pages : 259 pages
Book Rating : 4.5/5 (942 download)
Download or read book Liver, Nutrition, and Bile Acids written by G. Galli and published by Springer. This book was released on 2012-05-06 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a collection of the lectures and commu nications presented at the Nato Advanced Study Institute on "Liver, Nutrition and Bile Acids" held in Maratea, Italy, September 1983. The research areas covered by the Meeting are very wide, having to do with the liver and biliary pathophysiology, nutrition, gallstone disease and atherosclerosis prevention. Scientists from the major clinical and basic disciplines provided an update overview of the complex mechanisms regula ting the biosynthesis and catabolism of cholesterol and the formation and metabolism of bile acids. The NATO ASI has given the opportunity for thorough general discussions on problems of growing interest in medical sciences in the spirit of the NATO Meetings. This wealth of information is reflected in the present collection. We are grateful to all the contributors for the pre sentation of the results of their research. A particular thanks is addressed to Mrs. Brita Rolander Chilo of the Nutrition Foundation of Italy for her invaluable advice and for the organization of the Institute as well as for the editorial work. Giovanni Gall,i Enrica Bosisio v CONTENTS Coordinate Regulation of the Three Enzymes in Cholesterol Biosynthesis • •••••• 1 Ajit Sanghvi Microsomal Cholesterol 7a-Hydroxylase Phosphatases.
Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781719520
Total Pages : 848 pages
Book Rating : 4.7/5 (195 download)
Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Author : Gareth J. Jenkins
Publisher : Royal Society of Chemistry
ISBN 13 : 0854048464
Total Pages : 177 pages
Book Rating : 4.8/5 (54 download)
Download or read book Bile Acids written by Gareth J. Jenkins and published by Royal Society of Chemistry. This book was released on 2008 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bile acids are increasingly being seen as extremely important carcinogenic agents in cancers of the bile duct, liver, colon, rectum, and oesophagus. They are essential agents involved in lipid digestion and absorption in mammals, however, they also play wide-ranging roles in a variety of disease states ranging from diabetes to cancer. They have evolved exquisite mechanisms for controlling their own synthesis and to ensure that they are produced at correct concentrations and also kept in the correct anatomical environment. It is only when these fine levels of controls are breached that Bile aci.
Author : Stefano Fiorucci
Publisher : Springer Nature
ISBN 13 : 3030220052
Total Pages : 378 pages
Book Rating : 4.0/5 (32 download)
Download or read book Bile Acids and Their Receptors written by Stefano Fiorucci and published by Springer Nature. This book was released on 2019-09-03 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focusses on the latest results related to the field of bile acids as signaling molecules and describes how these receptors have become a major pharmacological target. It covers all major areas of research in this field, from genetics, chemistry, in silico modeling, molecular biology to clinical applications, offering a cross-country view of the functional role of bile acids as signaling molecules, virtually acting on all major areas of metabolism. While FXR and GPBAR1 are essential bile acid sensors that integrate the de novo bile acid synthesis with intestinal microbiota and liver metabolism, in a broader sense, BARs play a pathogenic role in the development of common human alignments including liver, intestinal and metabolic disorders, such as steatosis (NAFLD) and steato-hepatitis (NASH), diabetes, obesity and atherosclerosis.
Author : G.P. van Berge Henegouwen
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387688
Total Pages : 364 pages
Book Rating : 4.3/5 (876 download)
Download or read book Biology of Bile Acids in Health and Disease written by G.P. van Berge Henegouwen and published by Springer Science & Business Media. This book was released on 2001-05-31 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning in 1970, the International Bile Acid Meeting has taken place every two years and each time new progress in our understanding of the complex role of bile acids in many metabolic processes of the liver and the intestine has been revealed by a selected group of leading scientists from all over the world. Although originally mainly physiological data on bile acid synthesis and transport were emphasized, and later on also the therapeutic benefit of bile acids in gallstone disease and cholestasis was discovered, we have come now to the molecular biology and genetic era with major discoveries in transport defects and related diseases. This book is the proceedings of Falk Symposium No. 120, held in The Hague, The Netherlands, on October 12-13, 2000 - the 16th International Bile Acid Meeting. One of the main discoveries recently has been the identification of nuclear receptors for bile acids, which gives them a much broader perspective than previously anticipated. It even suggests that bile acids can regulate their biosynthesis and enterohepatic circulation transcriptionally. It will therefore not be surprising that this topic, together with the molecular regulation of cholesterol 7alpha-hydroxylase and cholesterol homeostasis, has a dominant place in these proceedings. Another important topic is the progress in our molecular understanding of hepatic (both at the basolateral and canalicular sites), cholangiocytic and intestinal bile acid transport processes. Further insights into genetic defects causing cholestasis or intestinal malabsorption in animal models and in human diseases are also discussed by a number of well-known authors. Finally the last section deals with new findings on the role of bile acid therapy in cholestatic syndromes or chemoprevention and with the potential benefit of bile acid inhibitors. All contributors provide an update on the most recent developments in their field.
Author : Pietro Vajro
Publisher : MDPI
ISBN 13 : 3038429236
Total Pages : 159 pages
Book Rating : 4.0/5 (384 download)
Download or read book Nutrition and Liver Disease written by Pietro Vajro and published by MDPI. This book was released on 2018-06-22 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Nutrition and Liver Disease" that was published in Nutrients
Author : Frederick J. Suchy
Publisher : Cambridge University Press
ISBN 13 : 1108911374
Total Pages : 875 pages
Book Rating : 4.1/5 (89 download)
Download or read book Liver Disease in Children written by Frederick J. Suchy and published by Cambridge University Press. This book was released on 2021-03-18 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.
Author : G. Paumgartner
Publisher : Springer
ISBN 13 :
Total Pages : 186 pages
Book Rating : 4.3/5 (91 download)
Download or read book Bile Acids in Liver Diseases written by G. Paumgartner and published by Springer. This book was released on 1995-12-31 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bile acid research has attracted increasing attention from both basic scientists and clinical hepatologists over the last decade. Experimental studies have expanded our knowledge of the role of bile acids in liver disease, and well-designed clinical trials have documented beneficial effects of bile acid treatment for a number of hepatobiliary diseases. Bile Acids in Liver Diseases, the proceedings of an International Falk Workshop held in Munich, January 1995, provides insights into current concepts in bile acid chemistry, bile acid synthesis and metabolism, and transport of bile acids across the hepatocyte. The role of bile acids in bile formation, cholestasis and hepatotoxicity are discussed. Finally, the book addresses experimental studies and hypotheses about the putative mechanisms of action of ursodeoxycholic acid in cholestatic liver diseases, and summarizes the clinical applications of bile acid treatment on the basis of controlled clinical trials.
Author : Dieter Häussinger
Publisher : Walter de Gruyter
ISBN 13 : 3110279347
Total Pages : 312 pages
Book Rating : 4.1/5 (12 download)
Download or read book Hepatobiliary Transport in Health and Disease written by Dieter Häussinger and published by Walter de Gruyter. This book was released on 2012-05-29 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: One major function of the liver is the uptake of endo- and xenobiotics from the bloodstream and their excretion into bile. The transport systems involved in hepatobiliary transport have been recently cloned and characterized at the molecular level and it is becoming clear that mutations and polymorphisms of individual transporter molecules underlie a variety of liver diseases. Furthermore, new research has shown that bile acids, whose function in digestion is long known, also behave as signal molecules in a variety of organs, including the intestinal and biliary epithelia, sinusoidal endothelial and immune cells. This book provides indepth surveys on the structure and function of transport molecules involved in hepatobiliary transport, on the role of different bile acids receptors in various organs and their function in health and disease, the mechanisms of bile salt-induced apoptosis and hepatocyte protection, and the role of transporter mutations as causes and modifiers of liver diseases. The book will be of interest not only for biochemists, structural chemists and biologists, but also for clinicians.
Author : G. Paumgartner
Publisher : Springer
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.3/5 (91 download)
Download or read book Bile Acids and the Liver written by G. Paumgartner and published by Springer. This book was released on 1987 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Pablo Muriel
Publisher : Academic Press
ISBN 13 : 0128043210
Total Pages : 917 pages
Book Rating : 4.1/5 (28 download)
Download or read book Liver Pathophysiology written by Pablo Muriel and published by Academic Press. This book was released on 2017-03-02 with total page 917 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.
Author : G. Paumgartner
Publisher : Springer
ISBN 13 :
Total Pages : 356 pages
Book Rating : 4.3/5 (91 download)
Download or read book Bile Acids and Hepatobiliary Diseases - Basic Research and Clinical Application written by G. Paumgartner and published by Springer. This book was released on 1997-06-30 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the last International Bile Acid Meeting in San Diego in 1994, new advances have been made in the understanding of bile acid metabolism and transport. The cytotoxic as well as the therapeutic effects of specific bile acids have been further explored and the beneficial effects of ursodeoxycholic acid in various chronic cholestatic conditions have been substantiated. Much basic and clinical research has been conducted to unravel the underlying mechanisms of action. This volume, the proceedings of Falk Symposium No. 93 (XIV International Bile Acid Meeting), held in Freiburg-im-Breisgau, Germany, October 22-24, 1996, is dedicated to both basic and clinical aspects of bile acid research related to the role of bile acids in hepatobiliary diseases.
Author : Elizabeth J. Carey
Publisher : Springer
ISBN 13 : 1493910132
Total Pages : 265 pages
Book Rating : 4.4/5 (939 download)
Download or read book Cholestatic Liver Disease written by Elizabeth J. Carey and published by Springer. This book was released on 2014-07-18 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition, there have been advances in both the diagnosis and the management of many of the cholestatic liver diseases. Cholestatic Liver Disease, Second Edition thoroughly updates the topics previously addressed, such as primary biliary cirrhosis, primary sclerosing cholangitis and cholestatic variants of drug hepatotoxicity and viral disease. New treatments, such as the development of the farnesoid X receptor agonists for the treatment of PBC, are highlighted. Current guidelines and areas of uncertainty are also covered. Additionally, new chapters have been added to reflect the changing landscape of cholestatic liver disease. Cholestatic Liver Disease, Second Edition is a concise yet comprehensive summary of the current status of the field and is of value to clinicians and researchers interested in patients with cholestatic liver disease provide that will help to guide patient management and stimulate investigative efforts.
Author : Michelle Lai
Publisher : Simon and Schuster
ISBN 13 : 1612434738
Total Pages : 121 pages
Book Rating : 4.6/5 (124 download)
Download or read book The Liver Healing Diet written by Michelle Lai and published by Simon and Schuster. This book was released on 2015-06-09 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to provide you with a detailed program for reversing liver damage through optimal nutrition—from two of the country’s top liver specialists. The only organ in your body that regenerates itself is the liver. And now, you can make it happen. With a complete program to rejuvenate your liver through optimal nutrition and routine exercise, The Liver Healing Diet shows you how to: Improve liver function Beat fatty liver disease Detoxify the liver Boost all-around health Nourish the body with delicious recipes The Liver Healing Diet teaches you basic liver facts, how to talk to your doctor about liver disease and what steps you need to reverse years of abuse. With your newly repaired liver you’ll feel better, have more energy and live a healthy lifestyle.
Author : G. Paumgartner
Publisher : Springer
ISBN 13 :
Total Pages : 356 pages
Book Rating : 4.3/5 (91 download)
Download or read book Bile Acids and the Hepatobiliary System written by G. Paumgartner and published by Springer. This book was released on 1993-06-30 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bile acids have recently found application in the treatment of hepatobiliary diseases. Chenodeoxycholic acid and ursodeoxycholic acid have proved to be effective agents for the dissolution of cholesterol gallstones, and ursodeoxycholic acid has been shown to have beneficial effects in patients with chronic cholestatic liver disease such as primary biliary cirrhosis or primary sclerosing cholangitis. The question of the long-term benefit for the patient remains open and the mechanism of action is still unclear. As a consequence, much basic and clinical research is being conducted on bile acid therapy. The XIIth International Bile Acid Meeting brought together researchers and clinicians from around the world, and was dedicated to basic and clinical aspects of the use of bile acids in the therapy of hepatobiliary disease.
