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Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Roland C. Aloia
Publisher :
ISBN 13 :
Total Pages : 320 pages
Book Rating : 4.3/5 (91 download)
Download or read book Lipid Domains and the Relationship to Membrane Function written by Roland C. Aloia and published by . This book was released on 1988 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 0128033274
Total Pages : 372 pages
Book Rating : 4.1/5 (28 download)
Download or read book Lipid Domains written by and published by Academic Press. This book was released on 2015-06-08 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up to date presentation of current knowledge in the field of Lipid Domains. Written by leading experts Contains original material, both textual and illustrative, that should become a very relevant reference material The material is presented in a very comprehensive manner Both researchers in the field and general readers should find relevant and up-to-date information
Author : Roland C. Aloia
Publisher : John Wiley & Sons
ISBN 13 : 9780471617426
Total Pages : 312 pages
Book Rating : 4.6/5 (174 download)
Download or read book Advances in Membrane Fluidity written by Roland C. Aloia and published by John Wiley & Sons. This book was released on 1988-01-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Peter J. Quinn
Publisher : Springer Science & Business Media
ISBN 13 : 1475758065
Total Pages : 502 pages
Book Rating : 4.4/5 (757 download)
Download or read book Membrane Dynamics and Domains written by Peter J. Quinn and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fluid-mosaic model of membrane structure formulated by Singer and Nicolson in the early 1970s has proven to be a durable concept in terms of the principles governing the organization of the constituent lipids and proteins. During the past 30 or so years a great deal of information has accumulated on the composition of various cell membranes and how this is related to the dif ferent functions that membranes perform. Nevertheless, the task of explaining particular functions at the molecular level has been hampered by lack of struc tural detail at the atomic level. The reason for this is primarily the difficulty of crystallizing membrane proteins which require strategies that differ from those used to crystallize soluble proteins. The unique exception is bacteriorhodopsin of the purple membrane of Halobacterium halobium which is interpolated into a membrane that is neither fluid nor in a mosaic configuration. To date only 50 or so membrane proteins have been characterised to atomic resolution by diffraction methods, in contrast to the vast data accumulated on soluble proteins. Another factor that has been difficult to explain is the reason why the lipid compliment of membranes is often extremely complex. Many hundreds of different molecular species of lipid can be identified in some membranes. Remarkably, the particular composition of each membrane appears to be main tained within relatively narrow limits and its identity distinguished from other morphologically-distinct membranes.
Author : C.Reyes Mateo
Publisher : Springer Science & Business Media
ISBN 13 : 9783540852827
Total Pages : 260 pages
Book Rating : 4.8/5 (528 download)
Download or read book Protein-Lipid Interactions written by C.Reyes Mateo and published by Springer Science & Business Media. This book was released on 2008-09-30 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological membranes have long been identified as key elements in a wide variety of cellular processes including cell defense communication, photosynthesis, signal transduction, and motility; thus they emerge as primary targets in both basic and applied research. This book brings together in a single volume the most recent views of experts in the area of protein–lipid interactions, providing an overview of the advances that have been achieved in the field in recent years, from very basic aspects to specialized technological applications. Topics include the application of X-ray and neutron diffraction, infrared and fluorescence spectroscopy, and high-resolution NMR to the understanding of the specific interactions between lipids and proteins within biological membranes, their structural relationships, and the implications for the biological functions that they mediate. Also covered in this volume are the insertion of proteins and peptides into the membrane and the concomitant formation of definite lipid domains within the membrane.
Author : Cyrus R. Safinya
Publisher : CRC Press
ISBN 13 : 0429527810
Total Pages : 800 pages
Book Rating : 4.4/5 (295 download)
Download or read book Handbook of Lipid Membranes written by Cyrus R. Safinya and published by CRC Press. This book was released on 2021-09-15 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides a comprehensive overview of lipid membrane fundamentals and applications. It gives the fundamental physical and biochemical aspects of membrane-related processes in living cells, and then relates them to how scientists are building bioinspired, artifical membrane-based systems such as gene delivery vehicles and synthetic membrane interfaces. It highlights the driving mechanism behind lipid self-assembly, membrane shape evolution, and vesicle trafficing, as well as the role of lipid membrane composition in signalling and the structural aspects of membranes in cellular integrity. Key Features: Includes a broad overview on the role of lipids as structural components of membranes, energy storage molecules, and signaling molecules. Covers lipids in signaling and the role of lipids in everyday life, from diet and health to cosmetics and pharmaceuticals. Discusses applications in nanotechnology and biomedicine, including liposomes in drug discovery, lipids for in vivo therapeutics, lipid-based sensors, artificial biointerfaces, and synthetic polymers. Includes an exciting section that explores the practical use of Archae lipids, lipids and the origins of life, and future outlook for the field. This book is a great companion for professionals in physics, biochemistry, physical chemistry and material sciences.
Author : Richard M. Epand
Publisher : Springer
ISBN 13 : 9811062447
Total Pages : 219 pages
Book Rating : 4.8/5 (11 download)
Download or read book The Biophysics of Cell Membranes written by Richard M. Epand and published by Springer. This book was released on 2017-09-25 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030937331X
Total Pages : 104 pages
Book Rating : 4.3/5 (93 download)
Download or read book Mesoscale Chemistry written by National Research Council and published by National Academies Press. This book was released on 2015-08-06 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last few decades great strides have been made in chemistry at the nanoscale, where the atomic granularity of matter and the exact positions of individual atoms are key determinants of structure and dynamics. Less attention, however, has been paid to the mesoscale--it is at this scale, in the range extending from large molecules (10 nm) through viruses to eukaryotic cells (10 microns), where interesting ensemble effects and the functionality that is critical to macroscopic phenomenon begins to manifest itself and cannot be described by laws on the scale of atoms and molecules alone. To further explore how knowledge about mesoscale phenomena can impact chemical research and development activities and vice versa, the Chemical Sciences Roundtable of the National Research Council convened a workshop on mesoscale chemistry in November 2014. With a focus on the research on chemical phenomena at the mesoscale, participants examined the opportunities that utilizing those behaviors can have for developing new catalysts, adding new functionality to materials, and increasing our understanding of biological and interfacial systems. The workshop also highlighted some of the challenges for analysis and description of mesoscale structures. This report summarizes the presentations and discussion of the workshop.
Author : Ole G. Mouritsen
Publisher : Springer Science & Business Media
ISBN 13 : 3540270760
Total Pages : 276 pages
Book Rating : 4.5/5 (42 download)
Download or read book Life - As a Matter of Fat written by Ole G. Mouritsen and published by Springer Science & Business Media. This book was released on 2006-03-30 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a multi-disciplinary perspective on the physics of life and the particular role played by lipids and the lipid-bilayer component of cell membranes. Emphasizes the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Shows how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nano-technology and biomedicine are also described.
Author : Daniel G.S. Capelluto
Publisher : Springer Science & Business Media
ISBN 13 : 940076331X
Total Pages : 219 pages
Book Rating : 4.4/5 (7 download)
Download or read book Lipid-mediated Protein Signaling written by Daniel G.S. Capelluto and published by Springer Science & Business Media. This book was released on 2013-06-17 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the most updated information of how membrane lipids mediate protein signaling from studies carried out in animal and plant cells. Also, there are some chapters that go beyond and expand these studies of protein-lipid interactions at the structural level. The book begins with a literature review from investigations associated to sphingolipids, followed by studies that describe the role of phosphoinositides in signaling and closing with the function of other key lipids in signaling at the plasma membrane and intracellular organelles.
Author : Mark P. Mattson
Publisher : Springer Science & Business Media
ISBN 13 : 1588293548
Total Pages : 219 pages
Book Rating : 4.5/5 (882 download)
Download or read book Membrane Microdomain Signaling written by Mark P. Mattson and published by Springer Science & Business Media. This book was released on 2005 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: From intramolecular asymmetries to raft assemblies: a short guide for the puzzled in lipidomics / Ephraim Yavin and Annette Brand -- Regulatory aspects of membrane microdomain (raft) dynamics in live cells: a biophysical approach / János Matkó and János Szöllosi -- Lipid raft membrane skeletons / Elizabeth J. Luna ... [et al.] -- Role of cholesterol in membrane microdomain signaling / Christopher J. Fielding -- Raft lipid metabolism in relation to alkyl-lysophospholipid-induced apoptosis / Arnold H. van der Luit, Marcel Verheij, and Wim J. van Blitterswijk -- Role of lipid rafts in signal transduction and synaptic plasticity of neural cells / Markus Delling and Melitta Schachner -- Role of rafts in virus fusion and budding / Wu Ou and Jonathan Silver -- Alterations in raft lipid metabolism in aging and neurodegenerative disorders / Mark P. Mattson, Roy G. Cutler, and Norman J. Haughey -- Caveolin and cancer: a complex relationship / Mordechai Liscovitch ... [et al.] -- Dietary modulation of lipid rafts: implications for disease prevention and treatment / Mark P. Mattson.
Author : Ole G. Mouritsen
Publisher : Springer
ISBN 13 : 3319226142
Total Pages : 298 pages
Book Rating : 4.3/5 (192 download)
Download or read book LIFE - AS A MATTER OF FAT written by Ole G. Mouritsen and published by Springer. This book was released on 2015-10-08 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book gives a multi-disciplinary perspective on the physics of life and the particular role played by lipids (fats) and the lipid-bilayer component of cell membranes. The emphasis is on the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Furthermore, it is shown how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nanotechnology and biomedicine are also described. The first edition of the present book was published in 2005 when lipidomics was still very much an emerging science and lipids about to be recognized as being as important for life as proteins, sugars, and genes. This significantly expanded and revised edition takes into account the tremendous amount of knowledge gained over the past decade. In addition, the book now includes more tutorial material on the biochemistry of lipids and the principles of lipid self-assembly. The book is aimed at undergraduate students and young research workers within physics, chemistry, biochemistry, molecular biology, nutrition, as well as pharmaceutical and biomedical sciences. From the reviews of the first edition: "This is a highly interesting book and a pleasure to read. It represents a new and excellent pedagogical introduction to the field of lipids and the biophysics of biological membranes. I reckon that physicists and chemists as well as biologists will benefit from this approach to the field and Mouritsen shows a deep insight into the physical chemistry of lipids." (Göran Lindblom, Chemistry and Physics of Lipids 2005, vol. 135, page 105-106) "The book takes the reader on an exciting journey through the lipid world, and Mouritsen attracts the attention with a lively style of writing ... . a comprehensive view of the ‘lipid sea’ can be easily achieved, gaining the right perspectives for envisaging future developments in the nascent field of lipidomics." (Carla Ferreri, ChemBioChem, Vol. 6 (8), 2005)
Author : Philip L. Yeagle
Publisher : CRC Press
ISBN 13 : 1439809585
Total Pages : 398 pages
Book Rating : 4.4/5 (398 download)
Download or read book The Structure of Biological Membranes written by Philip L. Yeagle and published by CRC Press. This book was released on 2011-07-18 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological membranes provide the fundamental structure of cells and viruses. Because much of what happens in a cell or in a virus occurs on, in, or across biological membranes, the study of membranes has rapidly permeated the fields of biology, pharmaceutical chemistry, and materials science. The Structure of Biological Membranes, Third Edition pro
Author : K.W.A. Wirtz
Publisher : Springer Science & Business Media
ISBN 13 : 1461528607
Total Pages : 319 pages
Book Rating : 4.4/5 (615 download)
Download or read book New Developments in Lipid-Protein Interactions and Receptor Function written by K.W.A. Wirtz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NATO Advanced Study Institute on "New Developments in Lipid-Protein Interactions and Receptor Function" was held on the Island of Spetsai, Greece, from August 16-27, 1992. This Institute was organized to bring together researchers in the field of membrane organization and dynamics with those actively involved in studies on receptor function, signal transduction mechanisms and gene regulation. 2 Presentations and discussions focussed on the regulation of intracellular Ca +-levels, on the second messengers derived from inositol lipids and on the specific phospholipase C isozymes involved in these processes. A major focus was on G-proteins and the effect of lipid anchors on their function. These principles of regulation were further discussed in the context of receptors for acetylcholine, lysophosphatidic acid and low-density lipoproteins. In addition, various aspects of the genomic regulation of cell growth and differentiation by transcription factors were presented. These topics were put into perspective by discussing the most recent developments in lipid-protein interactions, protein insertion into membranes, membrane lipid organization and lipid dynamics as mediated by phospholipid transfer proteins. This book presents the content of the major lectures and a selection of the most relevant of the most important topics posters. These proceedings offer a comprehensive account presented during the course of the Institute. The book is intended to make these proceedings accessible to a large audience.
Author : North Atlantic Treaty Organization. Scientific Affairs Division
Publisher : IOS Press
ISBN 13 : 9781586030087
Total Pages : 290 pages
Book Rating : 4.0/5 (3 download)
Download or read book Protein, Lipid and Membrane Traffic written by North Atlantic Treaty Organization. Scientific Affairs Division and published by IOS Press. This book was released on 2000 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text concentrates on the following specific topics: the dynamic character of lipids and proteins in biological membranes; the existence of specific domains in membranes including their visualisation; the molecular mechanisms of intracellular transport of membrane constituents and the involvement of lipid-protein interactions in these processes; protein assembly; structure and folding and transport through membranes; and the intracellular sorting and targeting of individual membrane components as well as different organelles."
Author : Alessandra Cambi
Publisher : CRC Press
ISBN 13 : 1482209896
Total Pages : 514 pages
Book Rating : 4.4/5 (822 download)
Download or read book Cell Membrane Nanodomains written by Alessandra Cambi and published by CRC Press. This book was released on 2014-10-27 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Membrane Nanodomains: From Biochemistry to Nanoscopy describes recent advances in our understanding of membrane organization, with a particular focus on the cutting-edge imaging techniques that are making these new discoveries possible. With contributions from pioneers in the field, the book explores areas where the application of these novel techniques reveals new concepts in biology. It assembles a collection of works where the integration of membrane biology and microscopy emphasizes the interdisciplinary nature of this exciting field. Beginning with a broad description of membrane organization, including seminal work on lipid partitioning in model systems and the roles of proteins in membrane organization, the book examines how lipids and membrane compartmentalization can regulate protein function and signal transduction. It then focuses on recent advances in imaging techniques and tools that foster further advances in our understanding of signaling nanoplatforms. The coverage includes several diffraction-limited imaging techniques that allow for measurements of protein distribution/clustering and membrane curvature in living cells, new fluorescent proteins, novel Laurdan analyses, and the toolbox of labeling possibilities with organic dyes. Since superresolution optical techniques have been crucial to advancing our understanding of cellular structure and protein behavior, the book concludes with a discussion of technologies that are enabling the visualization of lipids, proteins, and other molecular components at unprecedented spatiotemporal resolution. It also explains the ins and outs of the rapidly developing high- or superresolution microscopy field, including new methods and data analysis tools that exclusively pertain to these techniques. This integration of membrane biology and advanced imaging techniques emphasizes the interdisciplinary nature of this exciting field. The array of contributions from leading world experts makes this book a valuable tool for the visualization of signaling nanoplatforms by means of cutting-edge optical microscopy tools.
