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Author : Phillip C. Wankat
Publisher : CRC Press
ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.3/5 (91 download)
Download or read book Lg Scale Adsorption & Chromatography written by Phillip C. Wankat and published by CRC Press. This book was released on 1986-10-31 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Phillip C. Wankat
Publisher :
ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.3/5 (91 download)
Download or read book Large-scale Adsorption and Chromatography written by Phillip C. Wankat and published by . This book was released on 1986 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Giorgio Carta
Publisher : John Wiley & Sons
ISBN 13 : 352734666X
Total Pages : 440 pages
Book Rating : 4.5/5 (273 download)
Download or read book Protein Chromatography written by Giorgio Carta and published by John Wiley & Sons. This book was released on 2020-06-02 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: An all-in-one practical guide on how to efficiently use chromatographic separation methods Based on a training course that teaches the theoretical as well as practical aspects of protein bioseparation to bioprocess professionals, this fully updated and revised new edition offers comprehensive coverage of continuous chromatography and provides readers with many relevant examples from the biopharmaceutical industry. Divided into two large parts, Protein Chromatography: Process Development and Scale-Up, Second Edition presents all the necessary knowledge for effective process development in chromatographic bioseparation, both on small and large scale. The first part introduces chromatographic theory, including process design principles, to enable the reader to rationalize the set-up of a bioseparation process. The second part illustrates by way of case studies and sample protocols how the theory learned in the first part may be applied to real-life problems. Chapters look at: Downstream Processing of Biotechnology Products; Chromatography Media; Laboratory and Process Columns and Equipment; Adsorption Equilibrium; Rate Processes; and Dynamics of Chromatography Columns. The book closes with chapters on: Effects of Dispersion and Rate Processes on Column Performance; Gradient Elution Chromatography; and Chromatographic Column Design and Optimization. -Presents the most pertinent examples from the biopharmaceutical industry, including monoclonal antibodies -Provides an overview of the field along with design tools and examples illustrating the advantages of continuous processing in biopharmaceutical productions -Focuses on process development and large-scale bioseparation tasks, making it an ideal guide for the professional bioengineer in the biotech and pharma industries -Offers field-tested information based on decades of training courses for biotech and chemical engineers in Europe and the U.S. Protein Chromatography: Process Development and Scale-Up, Second Edition will appeal to biotechnologists, analytical chemists, chromatographers, chemical engineers, pharmaceutical industry, biotechnological industry, and biochemists.
Author : B. Mattiasson
Publisher : Springer Science & Business Media
ISBN 13 : 940171519X
Total Pages : 258 pages
Book Rating : 4.4/5 (17 download)
Download or read book Expanded Bed Chromatography written by B. Mattiasson and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanded bed adsorption chromatography is a novel processing technique for the purification of biomolecules, combining clarification, concentration and initial purification in one step. By such an integration it is possible to reduce the number of steps in the purification process, to shorten the processing time and to improve the yields. The technology is new, and interesting developments have taken place concerning the adsorbents, the processing technology and potential applications. Both small-scale laboratory processes and larger industrial processes are being developed. Expanded bed chromatography is one of the most exciting new developments in downstream processing in recent years. The technology will be a standard procedure when new biotechnological processes are being developed.
Author : Tingyue Gu
Publisher : Springer Science & Business Media
ISBN 13 : 3642795412
Total Pages : 139 pages
Book Rating : 4.6/5 (427 download)
Download or read book Mathematical Modeling and Scale-up of Liquid Chromatography written by Tingyue Gu and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liquid chromatography has proved to be one of the most important tools for separations. Rapid development in biotechnology has increased the demand for chromatography in analytical, preparative and large scale applications. The understanding of the dynamics of chromatography is imperative for the scale-up. This book is a systematic treatment of the general rate models for various forms of liquid chromatography including adsorption, size exclusion, affinity, reversed phase, hydrophobic interaction, and radial flow chromatography. Thermodynamic and mass transfer effects in liquid chromatography are discussed. Applications of computer programs for the rate models are described and the procedures for the scale-up of preparative- and large-scale liquid chromatography using the general rate models are given.
Author : G. Ganetsos
Publisher : CRC Press
ISBN 13 : 9780824787387
Total Pages : 812 pages
Book Rating : 4.7/5 (873 download)
Download or read book Preparative and Production Scale Chromatography written by G. Ganetsos and published by CRC Press. This book was released on 1992-09-16 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the latest developments in the scaling-up and application of chromatographic operations and demonstrates that production-scale chromatography is a powerful and invaluable separation process. The book covers every important process design and reveals actual, immediately applicable techniques and is designed to appeal to design, chemical/biochemical, and research and development engineers, process development managers, bioprocess technologists, analytical and clinical chemists and biochemists, pharmacists, and upper-level undergraduate, graduate, and continuing-education students in these disciplines.
Author : Geoffrey B. Cox
Publisher : John Wiley & Sons
ISBN 13 : 1405144718
Total Pages : 344 pages
Book Rating : 4.4/5 (51 download)
Download or read book Preparative Enantioselective Chromatography written by Geoffrey B. Cox and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of chiral liquid chromatography, facilitating thestraightforward separation of enantiomers, was a significantadvance in chromatography, leading to widespread application inanalytical chemistry. Application in preparative chromatography hasbeen less rapid, but with the development of single enantiomerpharmaceuticals its use is increasingly common in chemicalsynthesis at laboratory, pilot plant and even full productionscale. Brings non-experts up to speed quickly and comprehensively,facilitating the rapid development of effective separations ofenantiomeric mixtures on a range of process scales Presents case studies drawn from within the pharmaceuticalindustry to clearly illustrate the utility and value of preparativescale enantioselective chromatography in chemical research,development and production Key reference source and entry to the literature so the readerdoes not have to engage in expensive and time consuming literaturesearching
Author : Arne Staby
Publisher : John Wiley & Sons
ISBN 13 : 1119031176
Total Pages : 608 pages
Book Rating : 4.1/5 (19 download)
Download or read book Preparative Chromatography for Separation of Proteins written by Arne Staby and published by John Wiley & Sons. This book was released on 2017-02-02 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preparative Chromatography for Separation of Proteins addresses a wide range of modeling, techniques, strategies, and case studies of industrial separation of proteins and peptides. • Covers broad aspects of preparative chromatography with a unique combination of academic and industrial perspectives • Presents Combines modeling with compliantce useing of Quality-by-Design (QbD) approaches including modeling • Features a variety of chromatographic case studies not readily accessible to the general public • Represents an essential reference resource for academic, industrial, and pharmaceutical researchers
Author : G. Subramanian
Publisher : Ellis Horwood
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.3/5 (91 download)
Download or read book Preparative and Process-scale Liquid Chromatography written by G. Subramanian and published by Ellis Horwood. This book was released on 1991 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing the practical applications and limitations of each technique, this text on separations in liquid chromatography describes the cost-effectiveness of each operation and its theory. It also provides information on media design, column technology and packing materials.
Author : Ruth Freitag
Publisher : Springer
ISBN 13 : 3540453458
Total Pages : 276 pages
Book Rating : 4.5/5 (44 download)
Download or read book Modern Advances in Chromatography written by Ruth Freitag and published by Springer. This book was released on 2003-07-01 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromatography is the separation method for biological molecules from the analytical to the preparative scale. Few of the recent advances in life science, whether in "proteomics" or in the industrial production of recombinant therapeutics, would have been possible without the help of chromatographic separations. Concomitantly, chromatography nowadays stands for much more than a batch column packed with porous particles. In this book eminent experts from academia and industry introduce the reader to some of the recent new developments in this exciting area. Ranging from evolving nanoanalytical techniques to advances in the material sciences and artificial antibodies and finally continuous large scale separations of the most fragile biologicals, this book should provide interesting reading material for students and practitioners from various fields.
Author : C. B. Faust
Publisher :
ISBN 13 : 9781870343190
Total Pages : 184 pages
Book Rating : 4.3/5 (431 download)
Download or read book Modern Chemical Techniques written by C. B. Faust and published by . This book was released on 1992-01-01 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on a series of symposia that enabled individuals to update their chemical skills and learn about the newest methods, techniques, and instrumentation available.
Author : Ganapathy Subramanian
Publisher : John Wiley & Sons
ISBN 13 : 3527615601
Total Pages : 241 pages
Book Rating : 4.5/5 (276 download)
Download or read book Process Scale Liquid Chromatography written by Ganapathy Subramanian and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the industrial chromatographer and production scientist with a comprehensive account of process scale liquid chromatography. The basic theory is presented, guiding the reader through system design, simulation and modelling techniques, giving due consideration to economic aspects, as well as safety and regulatory factors. A thorough, up-to-date survey of current techniques and media does stress their advantages and limitations in such a way as to faciliate their application to real-life problems. In view of rapid rate of development in industrial chromatography one chapter provides an assessment of future developments. The chapters are written by acknowledged experts from Europe and the United States.
Author : H. Schmidt-Traub
Publisher : John Wiley & Sons
ISBN 13 : 3527649301
Total Pages : 545 pages
Book Rating : 4.5/5 (276 download)
Download or read book Preparative Chromatography written by H. Schmidt-Traub and published by John Wiley & Sons. This book was released on 2012-09-27 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and substantially extended to reflect the developments in this fast-changing field. It retains the interdisciplinary approach that elegantly combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. It also covers recent advances in preparative chromatographic processes for the separation of "smaller" molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants. The increase in biopharmaceutical substances is reflected by new and revised chapters on different modifications of continuous chromatography as well as ion-exchange chromatography and other separation principles widely used in biochromatography. Following an introductory section on the history of chromatography, the current state of research and the design of chromatographic processes, the book goes on to define the general terminology. There then follow sections on stationary phases, selection of chromatographic systems and process concepts. A completely new chapter deals with engineering and operation of chromatographic equipment. Final chapters on modeling and determination of model parameters as well as model based design, optimization and control of preparative chromatographic processes allow for optimal selection of chromatographic processes. Essential for chemists and chemical engineers in the chemical, pharmaceutical, and food industries.
Author : B.A. Bidlingmeyer
Publisher : Elsevier
ISBN 13 : 0080858414
Total Pages : 357 pages
Book Rating : 4.0/5 (88 download)
Download or read book Preparative Liquid Chromatography written by B.A. Bidlingmeyer and published by Elsevier. This book was released on 1987-07-01 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a straightforward approach to isolation and purification problems with a thorough presentation of preparative LC strategy including the interrelationship between the input and output of the instrumentation, while keeping to an application focus.The book stresses the practical aspects of preparative scale separations from TLC isolations through various laboratory scale column separations to very large scale production. It also gives a thorough description of the performance parameters (e.g. throughput, separation quality, etc.) as a function of operational parameters (e.g. particle size, column size, solvent usage, etc.). Experts in the field have contributed a well balanced presentation of separation development strategies from preparative TLC to commercial preparative process with practical examples in a wide variety of application areas such as drugs, proteins, nucleotides, industrial extracts, organic chemicals, enantiomers, polymers, etc.
Author : Kevin Robards
Publisher : Academic Press
ISBN 13 : 012822097X
Total Pages : 532 pages
Book Rating : 4.1/5 (282 download)
Download or read book Principles and Practice of Modern Chromatographic Methods written by Kevin Robards and published by Academic Press. This book was released on 2021-12-03 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Practice of Modern Chromatographic Methods, Second Edition takes a comprehensive, unified approach in its presentation of chromatographic techniques. Like the first edition, the book provides a scientifically rigid, but easy-to-follow presentation of chromatography concepts that begins with the purpose and intent of chromatographic theory - the “what and why that are left out of other books attempting to cover these principles. This fully revised second edition brings the content up-to-date, covering recent developments in several new sections and an additional chapter on composite methods. New topics include sample profiling, sample preparation, sustainable green chemistry, 2D chromatography, miniaturization/nano-LC, HILIC, and more. Contains thorough chapters that begin with an updated schematic overview and a visual representation of the content Avoids the obfuscation of different terminologies and classification systems that are prevalent in the area, such as the relationship between liquid chromatography and column chromatography Provides integrated and comprehensive topic coverage based on chromatographic bibliometrics and survey reports on the relative usage of chromatographic techniques
Author : Andreǐ Vladimirovich Kiselev
Publisher : Springer
ISBN 13 : 1489965033
Total Pages : 264 pages
Book Rating : 4.4/5 (899 download)
Download or read book Gas-Adsorption Chromatography written by Andreǐ Vladimirovich Kiselev and published by Springer. This book was released on 2013-11-21 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Barry Crittenden
Publisher : Elsevier
ISBN 13 : 0080489974
Total Pages : 283 pages
Book Rating : 4.0/5 (84 download)
Download or read book Adsorption Technology and Design written by Barry Crittenden and published by Elsevier. This book was released on 1998-02-17 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adsorption is of considerable industrial importance and is a major part of many different processes throughout the chemical and process industries, including many reactions - chemical and bio-chemical, purification and filtration, gas and liquid processing and catalysis. Adsorption is a complex process and this makes the correct design and implementation of its operation all the more critical. The aim of this book is to provide all those involved in designing and running adsorption processes with a straightforward guide to the essentials of adsorption technology and design. It will therefore be an important addition to the bookshelves of both student and professional chemical, plant and process engineers in industries as varied as the petrochemical, pharmaceutical and food processing fields. Adsorption is of considerable industrial importance and is a major part of many different processes throughout the chemical and process industries, including many reactions - chemical and bio-chemical, purification and filtration, gas and liquid processing and catalysis. Adsorption is a complex process and this makes the correct design and implementation of its operation all the more critical. The aim of this book is to provide all those involved in designing and running adsorption processes with a straightforward guide to the essentials of adsorption technology and design. It will therefore be an important addition to the bookshelves of both student and professional chemical, plant and process engineers in industries as varied as the petrochemical, pharmaceutical and food processing fields. This book is practically based - other books are research level monographs This is about the basic design and implementation of an important industrial process Written as a straightforward and concise guide
