Label Free Biosensors

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Label-Free Biosensing

Author : Michael J. Schöning
Publisher : Springer
ISBN 13 : 3319752200
Total Pages : 485 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Label-Free Biosensing by : Michael J. Schöning

Download or read book Label-Free Biosensing written by Michael J. Schöning and published by Springer. This book was released on 2018-07-20 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes the state-of-the-art technologies, key advances and future trends in the field of label-free biosensing. It provides detailed insights into the different types of solid-state, label-free biosensors, their underlying transducer principles, advanced materials utilized, device-fabrication techniques and various applications. The book offers graduate students, academic researchers, and industry professionals a comprehensive source of information on all facets of label-free biosensing and the future trends in this flourishing field. Highlights of the subjects covered include label-free biosensing with: · semiconductor field-effect devices such as nanomaterial-modified capacitive electrolyte-insulator-semiconductor structures, silicon nanowire transistors, III-nitride semiconductor devices and light-addressable potentiometric sensors · impedimetric biosensors using planar and 3D electrodes · nanocavity and solid-state nanopore devices · carbon nanotube and graphene/graphene oxide biosensors · electrochemical biosensors using molecularly imprinted polymers · biomimetic sensors based on acoustic signal transduction · enzyme logic systems and digital biosensors based on the biocomputing concept · heat-transfer as a novel transducer principle · ultrasensitive surface plasmon resonance biosensors · magnetic biosensors and magnetic imaging devices

Label-Free Biosensors

Author : Matthew A. Cooper
Publisher : Cambridge University Press
ISBN 13 : 1139476785
Total Pages : 305 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Label-Free Biosensors by : Matthew A. Cooper

Download or read book Label-Free Biosensors written by Matthew A. Cooper and published by Cambridge University Press. This book was released on 2009-02-02 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Label-free biosensors are devices that use biological or chemical receptors to detect analytes (molecules) in a sample. They give detailed information on the selectivity, affinity, and, in many cases, also the binding kinetics and thermodynamics of an interaction. Although they can be powerful tools in the hands of a skilled user, there is often a lack of knowledge of the best methods for using label-free assays to screen for biologically active molecules and accurately and precisely characterize molecular recognition events. This book reviews both established and newer label-free techniques giving both the expert user and the general reader interested in the technologies and applications behind label-free an insight into the field from expert opinion leaders and practitioners of the technologies. Most importantly, chapters contain worked examples from leaders in the field that take the reader through the basics of experimental design, setup, assay development, and data analysis.

Label-Free Biosensors

Author : Matthew A. Cooper
Publisher : Cambridge University Press
ISBN 13 : 0521884535
Total Pages : 317 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Label-Free Biosensors by : Matthew A. Cooper

Download or read book Label-Free Biosensors written by Matthew A. Cooper and published by Cambridge University Press. This book was released on 2009-02-02 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: A detailed technical review of label-free biosensor techniques with worked examples.

Label-Free Biosensor Methods in Drug Discovery

Author : Ye Fang
Publisher : Humana
ISBN 13 : 9781493926169
Total Pages : 0 pages
Book Rating : 4.9/5 (261 download)

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Book Synopsis Label-Free Biosensor Methods in Drug Discovery by : Ye Fang

Download or read book Label-Free Biosensor Methods in Drug Discovery written by Ye Fang and published by Humana. This book was released on 2015-04-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores label-free biosensors, advantageous in part because this technology bypasses the need of labels, reporters, and cell engineering, all of which are common to labeled techniques but may introduce artifacts in assay results. Addressing several fundamental and practical aspects as to how to implement label-free methods in the drug discovery process, this book covers a wide range of topics, including binding kinetics determination, fragment screening, antibody epitope mapping, protein-protein interaction profiling and screening, receptor pathway deconvolution, drug pharmacology profiling and screening, target identification, drug toxicity assessment, and physical phenotype profiling and diagnostics based on various cellular processes such as cell adhesion, migration, invasion, infection, and inflammation. As part of the Methods in Pharmacology and Toxicology series, chapters aim to provide key detail and implementation advice to aid with progress in the lab. Practical and thorough, Label-Free Biosensor Methods in Drug Discovery provides a new avenue for rapid access to a focused collection of highly regarded contributions in the field.

State of the Art in Biosensors

Author : Toonika Rinken
Publisher : BoD – Books on Demand
ISBN 13 : 9535110047
Total Pages : 364 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis State of the Art in Biosensors by : Toonika Rinken

Download or read book State of the Art in Biosensors written by Toonika Rinken and published by BoD – Books on Demand. This book was released on 2013-03-13 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: As biosensors comprise a prospective alternative to traditional chemical analyses, enabling fast on- and in-line measurements with sufficient selectivity, the field is expanding rapidly and is offering new ideas and developments every day. This book aims to cover the present state of the art in the biosensor technology and introduce the general aspects of biosensor- based techniques and methods. The book consists of 13 chapters by 44 authors and is divided into 3 sections, focused on bio-recognition techniques, signal transduction methods and signal analysis.

Biosensors and Biochips

Author : Alberto Pasquarelli
Publisher : Springer Nature
ISBN 13 : 3030764699
Total Pages : 342 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Biosensors and Biochips by : Alberto Pasquarelli

Download or read book Biosensors and Biochips written by Alberto Pasquarelli and published by Springer Nature. This book was released on 2021-10-29 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the basic principles and mechanism of action of biosensor systems, and introduces readers to the various types of biosensors; from affinity biosensors to catalytic, optical and label-free biosensors, the most common systems are explained in detail. Dedicated advanced sections focus on biochips and genome sequencing methods as well as organs-on-a-chip. The textbook helps readers to understand the elementary components of biosensors, and to identify and illustrate each function in the biosensor information flow, from recognition to transduction and transmission. Furthermore, readers will receive guidance in critically analyzing published studies on biosensor research, helping them to develop appropriate concepts and independently propose their own solutions. The textbook is intended for master’s students in bioengineering, biophysics, biotechnology and pharmacology that need a solid grasp of biosensor system technologies and applications, as well as students in related medical technological fields.

Label-Free Monitoring of Cells in vitro

Author : Joachim Wegener
Publisher : Springer Nature
ISBN 13 : 3030324338
Total Pages : 286 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Label-Free Monitoring of Cells in vitro by : Joachim Wegener

Download or read book Label-Free Monitoring of Cells in vitro written by Joachim Wegener and published by Springer Nature. This book was released on 2019-11-18 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is dedicated to label-free, non-invasive monitoring of cell-based assays and it comprises the most widely applied techniques. Each approach is described and critically evaluated by an expert in the field such that researchers get an overview on what is possible and where the limitations are. The book provides the theoretical basis for each technique as well as the most successful and exciting applications. Label-free bioanalytical techniques have been known for a long time as valuable tools to monitor adsorption processes at the solid-liquid interface in general – and biomolecular interaction analysis (BIA) in particular. The underlying concepts have been progressively transferred to the analysis of cell-based assays. The strength of these approaches is implicitly given with the name 'label-free': the readout is independent of any label, reagent or additive that contaminates the system under study and potentially affects its properties. Thus, label-free techniques provide an unbiased analytical perspective in the sense that the sample is not manipulated by additives but pure. They are commonly based on physical principles and read changes in integral physical properties of the sample like refractive index, conductivity, capacitance or elastic modulus to mention just a few. Even though it is not implied in the name, label-free approaches usually monitor the cells under study non-invasively meaning that the amplitude of the signal (e.g. electric field strength, mechanical elongation) that is used for the measurement is too low to interfere or affect. In contrast to label-based analytical techniques that are commonly restricted to a single reading at a predefined time point, label-free approaches allow for a continuous observation so that the dynamics of the biological system or reaction become accessible.

Biosensors – Recent Advances and Future Challenges

Author : Paolo Bollella
Publisher : MDPI
ISBN 13 : 3039438875
Total Pages : 504 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Biosensors – Recent Advances and Future Challenges by : Paolo Bollella

Download or read book Biosensors – Recent Advances and Future Challenges written by Paolo Bollella and published by MDPI. This book was released on 2021-01-27 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book is devoted to all aspects of biosensing in a very broad definition, including, but not limited to, biomolecular composition used in biosensors (e.g., biocatalytic enzymes, DNAzymes, abiotic nanospecies with biocatalytic features, bioreceptors, DNA/RNA, aptasensors, etc.), physical signal transduction mechanisms (e.g., electrochemical, optical, magnetic, etc.), engineering of different biosensing platforms, operation of biosensors in vitro and in vivo (implantable or wearable devices), self-powered biosensors, etc. The biosensors can be represented with analogue devices measuring concentrations of analytes and binary devices operating in the YES/NO format, possibly with logical processing of input signals. Furthermore, the book is aimed at attracting young scientists and introducing them to the field, while providing newcomers with an enormous collection of literature references.

Label-Free Biosensor

Author : Pengfei Zhang
Publisher :
ISBN 13 : 9783036578750
Total Pages : 0 pages
Book Rating : 4.5/5 (787 download)

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Book Synopsis Label-Free Biosensor by : Pengfei Zhang

Download or read book Label-Free Biosensor written by Pengfei Zhang and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, we have witnessed significant advancements in the label-free biosensing field. Label-free biosensors aim at detecting the target molecules or biological processes without labels, thus allowing evaluation of their intrinsic properties in their natural forms, as well as easy operations without sophisticated pre-treatments of samples, which has drawn more and more attention in biological studies and rapid clinical tests. The main challenges include two aspects. First, the measurement system should be sensitive enough to detect the tiny signals corresponding to the specific target properties. Second, the signal processing protocols should be able to recognize the signals from the complex background. Owing to the great advances of commercial detection components with high sensitivity, more and more ingenious but economic label-free biosensors have been presented for diverse applications. This Special Issue, entitled "Label-free Biosensors", focuses on recent advances in producing sensitive and easy-to-use label-free biosensors and their applications in diverse fields. This collection presents several novel label-free detection techniques to introduce design strategies and operation protocols in practical application, which might be of particular value to beginners and graduate students who have just entered this field.

Electrochemical DNA Biosensors

Author : Mehmet Sengun Ozsoz
Publisher : CRC Press
ISBN 13 : 9814241776
Total Pages : 568 pages
Book Rating : 4.8/5 (142 download)

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Book Synopsis Electrochemical DNA Biosensors by : Mehmet Sengun Ozsoz

Download or read book Electrochemical DNA Biosensors written by Mehmet Sengun Ozsoz and published by CRC Press. This book was released on 2012-04-23 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the basic electrochemical applications of DNA in various areas, from basic principles to the most recent discoveries. The book comprises theoretical and experimental analysis of various properties of nucleic acids, research methods, and some promising applications. The topics discussed in the book include electrochemical detection of DNA hybridization based on latex/gold nanoparticle and nanotubes; nanomaterial-based electrochemical DNA detection; electrochemical detection of microorganism-based DNA biosensors; gold nanoparticle-based electrochemical DNA biosensors; electrochemical detection of the aptamer-target interaction; nanoparticle-induced catalysis for DNA biosensing; basic terms regarding electrochemical DNA (nucleic acids) biosensors; screen-printed electrodes for electrochemical DNA detection; application of field-effect transistors to label free electrical DNA biosensor arrays; and electrochemical detection of nucleic acids using branched DNA amplifiers.

Lab-on-Fiber Technology

Author : Andrea Cusano
Publisher : Springer
ISBN 13 : 3319069985
Total Pages : 377 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Lab-on-Fiber Technology by : Andrea Cusano

Download or read book Lab-on-Fiber Technology written by Andrea Cusano and published by Springer. This book was released on 2014-07-29 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on a research field that is rapidly emerging as one of the most promising ones for the global optics and photonics community: the “lab-on-fiber” technology. Inspired by the well-established "lab on-a-chip" concept, this new technology essentially envisages novel and highly functionalized devices completely integrated into a single optical fiber for both communication and sensing applications. Based on the R&D experience of some of the world's leading authorities in the fields of optics, photonics, nanotechnology, and material science, this book provides a broad and accurate description of the main developments and achievements in the lab-on-fiber technology roadmap, also highlighting the new perspectives and challenges to be faced. This book is essential for scientists interested in the cutting-edge fiber optic technology, but also for graduate students.

Nanobiosensors

Author : Aiguo Wu
Publisher : John Wiley & Sons
ISBN 13 : 3527345108
Total Pages : 412 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Nanobiosensors by : Aiguo Wu

Download or read book Nanobiosensors written by Aiguo Wu and published by John Wiley & Sons. This book was released on 2020-06-02 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing cutting edge research on the hot topic of nanobiosensor, this book will become highly read Biosensor research has recently re-emerged as most vibrant area in recent years particularly after the advent of novel nanomaterials of multidimensional features and compositions. Nanomaterials of different types and striking properties have played a positive role in giving the boost and accelerated pace to biosensors development technology. Nanobiosensors - From Design to Applications covers several aspects of biosensors beginning from the basic concepts to advanced level research. It will help to bridge the gap between various aspects of biosensors development technology and applications. It covers biosensors related material in broad spectrum such as basic concepts, biosensors & their classification, biomarkers & their role in biosensors, nanostructures-based biosensors, applications of biosensors in human diseases, drug detection, toxins, and smart phone based biosensors. Nanobiosensors - From Design to Applications will prove a source of inspiration for research on biosensors, their local level development and consequently using for practical application in different industries such as food, biomedical diagnosis, pharmaceutics, agriculture, drug discovery, forensics, etc. * Discusses the latest technology and advances in the field of nanobiosensors and their applications in human diseases, drug detection, toxins * Offers a broad and comprehensive view of cutting-edge research on advanced materials such as carbon materials, nitride based nanomaterials, metal and metal oxide based nanomaterials for the fast-developing nanobiosensors research * Goes to a wide scientific and industry audience Nanobiosensors - From Design to Applications is a resource for polymer chemists, spectroscopists, materials scientists, physical chemists, surface chemists, and surface physicists.

Graphene Field-Effect Transistors

Author : Omar Azzaroni
Publisher : John Wiley & Sons
ISBN 13 : 3527349901
Total Pages : 453 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Graphene Field-Effect Transistors by : Omar Azzaroni

Download or read book Graphene Field-Effect Transistors written by Omar Azzaroni and published by John Wiley & Sons. This book was released on 2023-10-16 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Graphene Field-Effect Transistors In-depth resource on making and using graphene field effect transistors for point-of-care diagnostic devices Graphene Field-Effect Transistors focuses on the design, fabrication, characterization, and applications of graphene field effect transistors, summarizing the state-of-the-art in the field and putting forward new ideas regarding future research directions and potential applications. After a review of the unique electronic properties of graphene and the production of graphene and graphene oxide, the main part of the book is devoted to the fabrication of graphene field effect transistors and their sensing applications. Graphene Field-Effect Transistors includes information on: Electronic properties of graphene, production of graphene oxide and reduced graphene oxide, and graphene functionalization Fundamentals and fabrication of graphene field effect transistors, and nanomaterial/graphene nanostructure-based field-effect transistors Graphene field-effect transistors integrated with microfluidic platforms and flexible graphene field-effect transistors Graphene field-effect transistors for diagnostics applications, and DNA biosensors and immunosensors based on graphene field-effect transistors Graphene field-effect transistors for targeting cancer molecules, brain activity recording, bacterial detection, and detection of smell and taste Providing both fundamentals of the technology and an in-depth overview of using graphene field effect transistors for fabricating bioelectronic devices that can be applied for point-of-care diagnostics, Graphene Field-Effect Transistors is an essential reference for materials scientists, engineering scientists, laboratory medics, and biotechnologists.

Biosensors and Nanotechnology

Author : Zeynep Altintas
Publisher : John Wiley & Sons
ISBN 13 : 1119065011
Total Pages : 421 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Biosensors and Nanotechnology by : Zeynep Altintas

Download or read book Biosensors and Nanotechnology written by Zeynep Altintas and published by John Wiley & Sons. This book was released on 2017-12-18 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a broad range of information from basic principles to advanced applications of biosensors and nanomaterials in health care diagnostics This book utilizes a multidisciplinary approach to provide a wide range of information on biosensors and the impact of nanotechnology on the development of biosensors for health care. It offers a solid background on biosensors, recognition receptors, biomarkers, and disease diagnostics. An overview of biosensor-based health care applications is addressed. Nanomaterial applications in biosensors and diagnostics are included, covering the application of nanoparticles, magnetic nanomaterials, quantum dots, carbon nanotubes, graphene, and molecularly imprinted nanostructures. The topic of organ-specific health care systems utilizing biosensors is also incorporated to provide deep insight into the very recent advances in disease diagnostics. Biosensors and Nanotechnology: Applications in Health Care Diagnostics is comprised of 15 chapters that are presented in four sections and written by 33 researchers who are actively working in Germany, the United Kingdom, Italy, Turkey, Denmark, Finland, Romania, Malaysia and Brazil. It covers biomarkers in healthcare; microfluidics in medical diagnostics; SPR-based biosensor techniques; piezoelectric-based biosensor technologies; MEMS-based cell counting methods; lab-on-chip platforms; optical applications for cancer cases; and more. Discusses the latest technology and advances in the field of biosensors and their applications for healthcare diagnostics Particular focus on biosensors for cancer Summarizes research of the last 30 years, relating it to state-of-the-art technologies Biosensors and Nanotechnology: Applications in Health Care Diagnostics is an excellent book for researchers, scientists, regulators, consultants, and engineers in the field, as well as for graduate students studying the subject.

State of the Art in Biosensors

Author : Toonika Rinken
Publisher : BoD – Books on Demand
ISBN 13 : 9535110357
Total Pages : 326 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis State of the Art in Biosensors by : Toonika Rinken

Download or read book State of the Art in Biosensors written by Toonika Rinken and published by BoD – Books on Demand. This book was released on 2013-03-13 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main challenge in biosensor development is their application for various practical tasks to provide a continuous and reliable flow of information about the indicators of natural and industrial processes and the surroundings, so enabling adequate feedback and control. Biosensors can provide essential information, as the quality of life depends mainly on our knowledge about what we breathe, what we eat and how our bodies are able to metabolize the material, which we contact. This book includes 14 chapters, written by 52 authors and is focused on the applications of biosensors for monitoring the parameters of environment, the quality of food and biomarkers of health.

Biological and Medical Sensor Technologies

Author : Krzysztof Iniewski
Publisher : CRC Press
ISBN 13 : 1466552573
Total Pages : 412 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Biological and Medical Sensor Technologies by : Krzysztof Iniewski

Download or read book Biological and Medical Sensor Technologies written by Krzysztof Iniewski and published by CRC Press. This book was released on 2017-12-19 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological and Medical Sensor Technologies presents contributions from top experts who explore the development and implementation of sensors for various applications used in medicine and biology. Edited by a pioneer in the area of advanced semiconductor materials, the book is divided into two sections. The first part covers sensors for biological applications. Topics include: Advanced sensing and communication in the biological world DNA-derivative architectures for long-wavelength bio-sensing Label-free silicon photonics Quartz crystal microbalance-based biosensors Lab-on-chip technologies for cell-sensing applications Enzyme biosensors Future directions for breath sensors Solid-state gas sensors for clinical diagnosis The second part of the book deals with sensors for medical applications. This section addresses: Bio-sensing and human behavior measurements Sweat rate wearable sensors Various aspects of medical imaging The future of medical imaging Spatial and spectral resolution aspects of semiconductor detectors in medical imaging CMOS SSPM detectors CdTe detectors and their applications to gamma-ray imaging Positron emission tomography (PET) Composed of contributions from some of the world’s foremost experts in their respective fields, this book covers a wide range of subjects. It explores everything from sensors and communication systems found in nature to the latest advances in manmade sensors. The end result is a useful collection of stimulating insights into the many exciting applications of sensor technologies in everyday life.

Handbook of Cell Biosensors

Author : Gérald Thouand
Publisher : Springer
ISBN 13 : 9783030232160
Total Pages : 992 pages
Book Rating : 4.2/5 (321 download)

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Book Synopsis Handbook of Cell Biosensors by : Gérald Thouand

Download or read book Handbook of Cell Biosensors written by Gérald Thouand and published by Springer. This book was released on 2021-10-01 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is an interdisciplinary and comprehensive reference covering all aspects of cell biosensors. It is divided into four main sections which are led and organized by numerous international experts. The scope of coverage includes: Fundamentals and genetics for biosensor applications Transducers, Materials and Systems Markets, innovation and education Application of biosensors in business Biosensor research is an exciting hybrid world where biologists, chemists, physicists, engineers and computer engineers come together. This handbook will serve as an invaluable living resource for all researchers in academia and industry working with cell biosensors.