La Validation Au Sein De Lindustrie Pharmaceutique

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Rapport Sur L'état Et Les Tendances de la Toxicologie in Vitro Et Modifications Des Méthodologies Pour Réduire L'expérimentation Animale

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Author : J. P. W. Gilman
Publisher : Division de la toxicologie des médicaments, Bureau de recherche sur les médicaments, Santé et bien-être social Canada
ISBN 13 :
Total Pages : 256 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Rapport Sur L'état Et Les Tendances de la Toxicologie in Vitro Et Modifications Des Méthodologies Pour Réduire L'expérimentation Animale by : J. P. W. Gilman

Download or read book Rapport Sur L'état Et Les Tendances de la Toxicologie in Vitro Et Modifications Des Méthodologies Pour Réduire L'expérimentation Animale written by J. P. W. Gilman and published by Division de la toxicologie des médicaments, Bureau de recherche sur les médicaments, Santé et bien-être social Canada. This book was released on 1991 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary purposes of toxicological testing are the protection of human health and the safeguarding of the environment from excessive manmade contamination. Responsibility for setting safety standards and monitoring their implementation lies mainly with the federal departments of health, agriculture, and the environment. This report discusses in some detail the state-of-the-art of in vitro toxicology and other trends in alternative toxicological testing that may lead to a reduction in the use of animals for these purposes. It covers both the national and international fields, particularly in pharmaceuticals and biologicals. The toxicological testing of consumer chemicals, agricultural chemicals, and foods is also considered in less detail. The report focuses on Canada and the testing R & D undertaken in this country.

Sociologie et sociétés

Author :
Publisher :
ISBN 13 :
Total Pages : 832 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Sociologie et sociétés by :

Download or read book Sociologie et sociétés written by and published by . This book was released on 1995 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Innovate Bristol

Author : Sven Boermeester
Publisher :
ISBN 13 : 9781949677072
Total Pages : pages
Book Rating : 4.6/5 (77 download)

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Book Synopsis Innovate Bristol by : Sven Boermeester

Download or read book Innovate Bristol written by Sven Boermeester and published by . This book was released on 2019-12 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Innovate Bristol highlights and celebrates those companies and individuals that are actively working at building a better tomorrow for all. Innovation Ecosystems thrive through the involvement and support of companies and individuals from all industries, which is why the Innovate series not only focuses on the innovators but also those people whom the Innovation Ecosystem, would not be able to thrive without.

The Seine River Basin

Author : Nicolas Flipo
Publisher : Springer Nature
ISBN 13 : 3030542602
Total Pages : 430 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis The Seine River Basin by : Nicolas Flipo

Download or read book The Seine River Basin written by Nicolas Flipo and published by Springer Nature. This book was released on 2021-01-30 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book reviews the water-agro-food and socio-eco-system of the Seine River basin (76,000 km2), and offers a historical perspective on the river’s long-term contamination. The Seine basin is inhabited by circa 17 million people and is impacted by intensive agricultural practices and industrial activities. These pressures have gradually affected its hydrological, chemical and ecological functioning, leading to a maximum chemical degradation between the 1960s and the 1990s. Over the last three decades, while major water-quality improvements have been observed, new issues (e.g. endocrine disruptors, microplastics) have also emerged. The state of the Seine River network, from the headwaters to estuary, is increasingly controlled by the balance between pressures and social responses. This socio-ecosystem provides a unique example of the functioning of a territory under heavy anthropogenic pressure during the Anthropocene era. The achievements made were possible due to the long-term PIREN Seine research program, established in 1989 and today part of the French socio-ecological research network “Zones Ateliers”, itself part of the international Long-term Socio-economic and Ecological Research Network (LTSER). Written by experts in the field, the book provides an introduction to the water budget and the territorial metabolism of the Seine basin, and studies the trajectories and impact of various pollutants in the Seine River. It offers insights into the ecological functioning, the integration of agricultural practices, the analysis of aquatic organic matter, and the evolution of fish assemblages in the Seine basin, and also presents research perspectives and approaches to improve the water quality of the Seine River. Given its scope, it will appeal to environmental managers, scientists and policymakers interested in the long-term contamination of the Seine River.

3D Printing of Pharmaceuticals

Author : Abdul W. Basit
Publisher : Springer
ISBN 13 : 3319907557
Total Pages : 246 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis 3D Printing of Pharmaceuticals by : Abdul W. Basit

Download or read book 3D Printing of Pharmaceuticals written by Abdul W. Basit and published by Springer. This book was released on 2018-08-06 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: 3D printing is forecast to revolutionise the pharmaceutical sector, changing the face of medicine development, manufacture and use. Potential applications range from pre-clinical drug development and dosage form design through to the fabrication of functionalised implants and regenerative medicine. Within clinical pharmacy practice, printing technologies may finally lead to the concept of personalised medicines becoming a reality. This volume aims to be the definitive resource for anyone thinking of developing or using 3D printing technologies in the pharmaceutical sector, with a strong focus on the translation of printing technologies to a clinical setting. This text brings together leading experts to provide extensive information on an array of 3D printing techniques, reviewing the current printing technologies in the pharmaceutical manufacturing supply chain, in particular, highlighting the state-of-the-art applications in medicine and discussing modern drug product manufacture from a regulatory perspective. This book is a highly valuable resource for a range of demographics, including academic researchers and the pharmaceutical industry, providing a comprehensive inventory detailing the current and future applications of 3D printing in pharmaceuticals. Abdul W. Basit is Professor of Pharmaceutics at the UCL School of Pharmacy, University College London. Abdul’s research sits at the interface between pharmaceutical science and gastroenterology, forging links between basic science and clinical outcomes. He leads a large and multidisciplinary research group, and the goal of his work is to further the understanding of gastrointestinal physiology by fundamental research. So far, this knowledge has been translated into the design of new technologies and improved disease treatments, many of which are currently in late-stage clinical trials. He has published over 350 papers, book chapters and abstracts and delivered more than 250 invited research presentations. Abdul is also a serial entrepreneur and has filed 25 patents and founded 3 pharmaceutical companies (Kuecept, Intract Pharma, FabRx). Abdul is a frequent speaker at international conferences, serves as a consultant to many pharmaceutical companies and is on the advisory boards of scientific journals, healthcare organisations and charitable bodies. He is the European Editor of the International Journal of Pharmaceutics. Abdul was the recipient of the Young Investigator Award in Pharmaceutics and Pharmaceutical Technology from the American Association of Pharmaceutical Scientists (AAPS) and is the only non-North American scientist to receive this award. He was also the recipient of the Academy of Pharmaceutical Sciences (APS) award. Simon Gaisford holds a Chair in Pharmaceutics and is Head of the Department of Pharmaceutics at the UCL School of Pharmacy, University College London. He has published 110 papers, 8 book chapters and 4 authored books. His research is focused on novel technologies for manufacturing medicines, particularly using ink-jet printing and 3D printing, and he is an expert in the physico-chemical characterisation of compounds and formulations with thermal methods and calorimetry.

Patient Involvement in Health Technology Assessment

Author : Karen M. Facey
Publisher : Springer
ISBN 13 : 9811040680
Total Pages : 431 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Patient Involvement in Health Technology Assessment by : Karen M. Facey

Download or read book Patient Involvement in Health Technology Assessment written by Karen M. Facey and published by Springer. This book was released on 2017-05-15 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to offer a comprehensive guide to involving patients in health technology assessment (HTA). Defining patient involvement as patient participation in the HTA process and research into patient aspects, this book includes detailed explanations of approaches to participation and research, as well as case studies. Patient Involvement in HTA enables researchers, postgraduate students, HTA professionals and experts in the HTA community to study these complementary ways of taking account of patients’ knowledge, experiences, needs and preferences. Part I includes chapters discussing the ethical rationale, terminology, patient-based evidence, participation and patient input. Part II sets out methodology including: Qualitative Evidence Synthesis, Discrete Choice Experiments, Analytical Hierarchy Processes, Ethnographic Fieldwork, Deliberative Methods, Social Media Analysis, Patient-Reported Outcome Measures, patients as collaborative research partners and evaluation. Part III contains 15 case studies setting out current activities by HTA bodies on five continents, health technology developers and patient organisations. Each part includes discussion chapters from leading experts in patient involvement. A final chapter reflects on the need to clearly define the goals for patient involvement within the context of the HTA to identify the optimal approach. With cohesive contributions from more than 80 authors from a variety of disciplines around the globe, it is hoped this book will serve as a catalyst for collaboration to further develop patient involvement to improve HTA. "If you’re not involving patients, you're not doing HTA!" - Dr. Brian O’Rourke, President and CEO of CADTH, Chair of INAHTA

Applied Artificial Intelligence: Where AI Can Be Used In Business

Author : Francesco Corea
Publisher : Springer
ISBN 13 : 331977252X
Total Pages : 47 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Applied Artificial Intelligence: Where AI Can Be Used In Business by : Francesco Corea

Download or read book Applied Artificial Intelligence: Where AI Can Be Used In Business written by Francesco Corea and published by Springer. This book was released on 2018-03-09 with total page 47 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with artificial intelligence (AI) and its several applications. It is not an organic text that should be read from the first page onwards, but rather a collection of articles that can be read at will (or at need). The idea of this work is indeed to provide some food for thoughts on how AI is impacting few verticals (insurance and financial services), affecting horizontal and technical applications (speech recognition and blockchain), and changing organizational structures (introducing new figures or dealing with ethical issues). The structure of the chapter is very similar, so I hope the reader won’t find difficulties in establishing comparisons or understanding the differences between specific problems AI is being used for. The first chapter of the book is indeed showing the potential and the achievements of new AI techniques in the speech recognition domain, touching upon the topics of bots and conversational interfaces. The second and thirds chapter tackle instead verticals that are historically data-intensive but not data-driven, i.e., the financial sector and the insurance one. The following part of the book is the more technical one (and probably the most innovative), because looks at AI and its intersection with another exponential technology, namely the blockchain. Finally, the last chapters are instead more operative, because they concern new figures to be hired regardless of the organization or the sector, and ethical and moral issues related to the creation and implementation of new type of algorithms.

Chemical Analysis

Author : Francis Rouessac
Publisher : John Wiley & Sons
ISBN 13 : 1118681878
Total Pages : 494 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Chemical Analysis by : Francis Rouessac

Download or read book Chemical Analysis written by Francis Rouessac and published by John Wiley & Sons. This book was released on 2013-05-06 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, Chemical Analysis: Second Edition is an essential introduction to a wide range of analytical techniques and instruments. Assuming little in the way of prior knowledge, this text carefully guides the reader through the more widely used and important techniques, whilst avoiding excessive technical detail. Provides a thorough introduction to a wide range of the most important and widely used instrumental techniques Maintains a careful balance between depth and breadth of coverage Includes examples, problems and their solutions Includes coverage of latest developments including supercritical fluid chromatography and capillary electrophoresis

Value Creation in the Pharmaceutical Industry

Author : Alexander Schuhmacher
Publisher : John Wiley & Sons
ISBN 13 : 3527339132
Total Pages : 511 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Value Creation in the Pharmaceutical Industry by : Alexander Schuhmacher

Download or read book Value Creation in the Pharmaceutical Industry written by Alexander Schuhmacher and published by John Wiley & Sons. This book was released on 2016-04-11 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide for advanced students and decision-makers in the pharma and biotech industry presents key success factors in R&D along with value creators in pharmaceutical innovation. A team of editors and authors with extensive experience in academia and industry and at some of the most prestigious business schools in Europe discusses in detail the innovation process in pharma as well as common and new research and innovation strategies. In doing so, they cover collaboration and partnerships, open innovation, biopharmaceuticals, translational medicine, good manufacturing practice, regulatory affairs, and portfolio management. Each chapter covers controversial aspects of recent developments in the pharmaceutical industry, with the aim of stimulating productive debates on the most effective and efficient innovation processes. A must-have for young professionals and MBA students preparing to enter R&D in pharma or biotech as well as for students on a combined BA/biomedical and natural sciences program.

Biosocialities, Genetics and the Social Sciences

Author : Sahra Gibbon
Publisher : Routledge
ISBN 13 : 1134144725
Total Pages : 387 pages
Book Rating : 4.1/5 (341 download)

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Book Synopsis Biosocialities, Genetics and the Social Sciences by : Sahra Gibbon

Download or read book Biosocialities, Genetics and the Social Sciences written by Sahra Gibbon and published by Routledge. This book was released on 2007-07-20 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosocialities, Genetics and the Social Sciences explores the social, cultural and economic transformations that result from innovations in genomic knowledge and technology. This pioneering collection uses Paul Rabinow’s concept of biosociality to chart the shifts in social relations and ideas about nature, biology and identity brought about by developments in biomedicine. Based on new empirical research, it contains chapters on genomic research into embryonic stem cell therapy, breast cancer, autism, Parkinson’s and IVF treatment, as well as on the expectations and education surrounding genomic research. It covers four main themes: novel modes of identity and identification, such as genetic citizenship the role of institutions, ranging from disease advocacy organizations and voluntary organizations to the state the production of biological knowledge, novel life-forms, and technologies the generation of wealth and commercial interests in biology. Including an afterword by Paul Rabinow and case studies on the UK, US, Canada, Germany, India and Israel, this book is key reading for students and researchers of the new genetics and the social sciences – particularly medical sociologists, medical anthropologists and those involved with science and technology studies.

Preparative Layer Chromatography

Author : Teresa Kowalska
Publisher : CRC Press
ISBN 13 : 1420005820
Total Pages : 441 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Preparative Layer Chromatography by : Teresa Kowalska

Download or read book Preparative Layer Chromatography written by Teresa Kowalska and published by CRC Press. This book was released on 2006-02-03 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preparative Layer Chromatography explains how this method is used for separating large quantities of mixtures containing a wide variety of important compounds. It offers a broad review of preparative layer chromatography (PLC) applications and adaptable working procedures for microseparations involving organic, inorganic, and organometallic compoun

Faecal Sludge Management

Author : Linda Strande
Publisher : IWA Publishing
ISBN 13 : 1780404735
Total Pages : 428 pages
Book Rating : 4.7/5 (84 download)

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Book Synopsis Faecal Sludge Management by : Linda Strande

Download or read book Faecal Sludge Management written by Linda Strande and published by IWA Publishing. This book was released on 2014-08-15 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is estimated that literally billions of residents in urban and peri-urban areas of Africa, Asia, and Latin America are served by onsite sanitation systems (e.g. various types of latrines and septic tanks). Until recently, the management of faecal sludge from these onsite systems has been grossly neglected, partially as a result of them being considered temporary solutions until sewer-based systems could be implemented. However, the perception of onsite or decentralized sanitation technologies for urban areas is gradually changing, and is increasingly being considered as long-term, sustainable options in urban areas, especially in low- and middle-income countries that lack sewer infrastructures. This is the first book dedicated to faecal sludge management. It compiles the current state of knowledge of the rapidly evolving field of faecal sludge management, and presents an integrated approach that includes technology, management, and planning based on Sandecs 20 years of experience in the field. Faecal Sludge Management: Systems Approach for Implementation and Operation addresses the organization of the entire faecal sludge management service chain, from the collection and transport of sludge, and the current state of knowledge of treatment options, to the final end use or disposal of treated sludge. The book also presents important factors to consider when evaluating and upscaling new treatment technology options. The book is designed for undergraduate and graduate students, and engineers and practitioners in the field who have some basic knowledge of environmental and/or wastewater engineering.

2nd Pan-African Symposium on the Sustainable Use of Natural Resources in Africa

Author : Bihini won wa Musiti
Publisher : IUCN
ISBN 13 : 2831706904
Total Pages : 344 pages
Book Rating : 4.8/5 (317 download)

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Book Synopsis 2nd Pan-African Symposium on the Sustainable Use of Natural Resources in Africa by : Bihini won wa Musiti

Download or read book 2nd Pan-African Symposium on the Sustainable Use of Natural Resources in Africa written by Bihini won wa Musiti and published by IUCN. This book was released on 2003 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This bilingual publication results from a four-day symposium aimed at capturing the general directions and analytical issues that characterize approaches to sustainable use in Africa. The papers included in this work are organized under four major headings: modes of use, devolution, scale issues and external issues. Authors explore these themes through the use of case studies and the description of specific regional experiences. External issues are further explored in a series of commissioned policy papers which have also been included.

Fortieth Report of the WHO Expert Committee on Specifications for Pharmaceutical Preparations

Author :
Publisher :
ISBN 13 : 9789241209373
Total Pages : 0 pages
Book Rating : 4.2/5 (93 download)

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Book Synopsis Fortieth Report of the WHO Expert Committee on Specifications for Pharmaceutical Preparations by :

Download or read book Fortieth Report of the WHO Expert Committee on Specifications for Pharmaceutical Preparations written by and published by . This book was released on 2006 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Life-Cycle of Pharmaceuticals in the Environment

Author : B.M. Peake
Publisher : Elsevier
ISBN 13 : 190881845X
Total Pages : 272 pages
Book Rating : 4.9/5 (88 download)

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Book Synopsis The Life-Cycle of Pharmaceuticals in the Environment by : B.M. Peake

Download or read book The Life-Cycle of Pharmaceuticals in the Environment written by B.M. Peake and published by Elsevier. This book was released on 2015-11-13 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Life-Cycle of Pharmaceuticals in the Environment identifies pathways of entry of pharmaceuticals into the environment, beginning with the role of global prescribing and disposal practices. The book then discusses typical levels of common pharmaceuticals and how they can be determined in natural waters such as raw and treated sewage, and in potable water. In addition, sections examine methods currently available to degrade pharmaceuticals in natural waters and some of their ecotoxicological impacts, along with future considerations and the growing concept of product stewardship. - Encompasses the full lifecycle of common pharmaceuticals, from prescription and dispensing practices to their occurrence in a range of different types of natural waters and their environmental impact - Explores the role of the healthcare system and its affect on users - Beneficial for environmental engineers involved in the design and operation of appropriate degradation technologies of the pharmaceutical prescription and disposal practices

Single-Use Technology in Biopharmaceutical Manufacture

Author : Regine Eibl
Publisher : John Wiley & Sons
ISBN 13 : 1119477786
Total Pages : 367 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Single-Use Technology in Biopharmaceutical Manufacture by : Regine Eibl

Download or read book Single-Use Technology in Biopharmaceutical Manufacture written by Regine Eibl and published by John Wiley & Sons. This book was released on 2019-07-18 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authoritative guide to the principles, characteristics, engineering aspects, economics, and applications of disposables in the manufacture of biopharmaceuticals The revised and updated second edition of Single-Use Technology in Biopharmaceutical Manufacture offers a comprehensive examination of the most-commonly used disposables in the manufacture of biopharmaceuticals. The authors—noted experts on the topic—provide the essential information on the principles, characteristics, engineering aspects, economics, and applications. This authoritative guide contains the basic knowledge and information about disposable equipment. The author also discusses biopharmaceuticals’ applications through the lens of case studies that clearly illustrate the role of manufacturing, quality assurance, and environmental influences. This updated second edition revises existing information with recent developments that have taken place since the first edition was published. The book also presents the latest advances in the field of single-use technology and explores topics including applying single-use devices for microorganisms, human mesenchymal stem cells, and T-cells. This important book: • Contains an updated and end-to-end view of the development and manufacturing of single-use biologics • Helps in the identification of appropriate disposables and relevant vendors • Offers illustrative case studies that examine manufacturing, quality assurance, and environmental influences • Includes updated coverage on cross-functional/transversal dependencies, significant improvements made by suppliers, and the successful application of the single-use technologies Written for biopharmaceutical manufacturers, process developers, and biological and chemical engineers, Single-Use Technology in Biopharmaceutical Manufacture, 2nd Edition provides the information needed for professionals to come to an easier decision for or against disposable alternatives and to choose the appropriate system.

Open Government

Author : Daniel Lathrop
Publisher : "O'Reilly Media, Inc."
ISBN 13 : 1449388809
Total Pages : 434 pages
Book Rating : 4.4/5 (493 download)

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Book Synopsis Open Government by : Daniel Lathrop

Download or read book Open Government written by Daniel Lathrop and published by "O'Reilly Media, Inc.". This book was released on 2010-02-08 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a world where web services can make real-time data accessible to anyone, how can the government leverage this openness to improve its operations and increase citizen participation and awareness? Through a collection of essays and case studies, leading visionaries and practitioners both inside and outside of government share their ideas on how to achieve and direct this emerging world of online collaboration, transparency, and participation. Contributions and topics include: Beth Simone Noveck, U.S. Deputy Chief Technology Officer for open government, "The Single Point of Failure" Jerry Brito, senior research fellow at the Mercatus Center at George Mason University, "All Your Data Are Belong to Us: Liberating Government Data" Aaron Swartz, cofounder of reddit.com, OpenLibrary.org, and BoldProgressives.org, "When Is Transparency Useful?" Ellen S. Miller, executive director of the Sunlight Foundation, "Disrupting Washington's Golden Rule" Carl Malamud, founder of Public.Resource.Org, "By the People" Douglas Schuler, president of the Public Sphere Project, "Online Deliberation and Civic Intelligence" Howard Dierking, program manager on Microsoft's MSDN and TechNet Web platform team, "Engineering Good Government" Matthew Burton, Web entrepreneur and former intelligence analyst at the Defense Intelligence Agency, "A Peace Corps for Programmers" Gary D. Bass and Sean Moulton, OMB Watch, "Bringing the Web 2.0 Revolution to Government" Tim O'Reilly, founder and CEO of O'Reilly Media, "Defining Government 2.0: Lessons Learned from the Success of Computer Platforms" Open Government editors: Daniel Lathrop is a former investigative projects reporter with the Seattle Post Intelligencer who's covered politics in Washington state, Iowa, Florida, and Washington D.C. He's a specialist in campaign finance and "computer-assisted reporting" -- the practice of using data analysis to report the news. Laurel Ruma is the Gov 2.0 Evangelist at O'Reilly Media. She is also co-chair for the Gov 2.0 Expo.