It All Depends on the Dose

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Publisher : Routledge
ISBN 13 : 1315521075
Total Pages : 413 pages
Book Rating : 4.3/5 (155 download)

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Book Synopsis It All Depends on the Dose by : Ole Peter Grell

Download or read book It All Depends on the Dose written by Ole Peter Grell and published by Routledge. This book was released on 2018-05-11 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first volume to take a broad historical sweep of the close relation between medicines and poisons in the Western tradition, and their interconnectedness. They are like two ends of a spectrum, for the same natural material can be medicine or poison, depending on the dose, and poisons can be transformed into medicines, while medicines can turn out to be poisons. The book looks at important moments in the history of the relationship between poisons and medicines in European history, from Roman times, with the Greek physician Galen, through the Renaissance and the maverick physician Paracelsus, to the present, when poisons are actively being turned into beneficial medicines.

It All Depends on the Dose

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Author :
Publisher : Routledge
ISBN 13 : 1315521083
Total Pages : 259 pages
Book Rating : 4.3/5 (155 download)

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Book Synopsis It All Depends on the Dose by : Ole Peter Grell

Download or read book It All Depends on the Dose written by Ole Peter Grell and published by Routledge. This book was released on 2018-05-11 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first volume to take a broad historical sweep of the close relation between medicines and poisons in the Western tradition, and their interconnectedness. They are like two ends of a spectrum, for the same natural material can be medicine or poison, depending on the dose, and poisons can be transformed into medicines, while medicines can turn out to be poisons. The book looks at important moments in the history of the relationship between poisons and medicines in European history, from Roman times, with the Greek physician Galen, through the Renaissance and the maverick physician Paracelsus, to the present, when poisons are actively being turned into beneficial medicines. Chapter 5 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.

"It All Depends on the Dose"

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Author :
Publisher : Routledge
ISBN 13 : 9781032401911
Total Pages : 0 pages
Book Rating : 4.4/5 (19 download)

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Book Synopsis "It All Depends on the Dose" by : Ole Peter Grell

Download or read book "It All Depends on the Dose" written by Ole Peter Grell and published by Routledge. This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first volume to take a broad historical sweep of the close relation between medicines and poisons in the Western tradition, and their interconnectedness. They are like two ends of a spectrum, for the same natural material can be medicine or poison, depending on the dose, and poisons can be transformed into medicines, while medicines can turn out to be poisons. The book looks at important moments in the history of the relationship between poisons and medicines in European history, from Roman times, with the Greek physician Galen, through the Renaissance and the maverick physican Paracelsus, to the present, when poisons are actively being turned into beneficial medicines. Book jacket.

Holland-Frei Cancer Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2008 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Science and Decisions

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Publisher : National Academies Press
ISBN 13 : 0309120462
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Science and Decisions by : National Research Council

Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Pharmacovigilance for Herbal and Traditional Medicines

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Publisher : Springer Nature
ISBN 13 : 3031072758
Total Pages : 406 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Pharmacovigilance for Herbal and Traditional Medicines by : Joanne Barnes

Download or read book Pharmacovigilance for Herbal and Traditional Medicines written by Joanne Barnes and published by Springer Nature. This book was released on 2022-08-11 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: This remarkable new book is the first text dedicated to the topic of pharmacovigilance for herbal and traditional medicines. Taking a truly global perspective, this volume draws together contributions from a diverse group of experts, writing on current knowledge and practices in pharmacovigilance for herbal and traditional medicines, and on advances and innovation in monitoring the safety of this unique and complex category of products and preparations. In part one, the book discusses the current status of pharmacovigilance for herbal and traditional medicines, including the importance of natural products chemistry to harms, and its relevance in considering how pharmacovigilance for these products could be undertaken. Several other chapters discuss methodological approaches and ongoing challenges in pharmacovigilance for herbal and traditional medicines, including issues relating to nomenclature, coding and classification, and the nuances involved in causality assessment. Part two of the book focusses on pharmacovigilance for herbal and traditional medicines around the world, with chapters from authors in several different countries representing diverse historical, ethnic, cultural, social and political contexts. These chapters provide deeper insights and perspectives into spontaneous reporting for herbal and traditional medicines in those countries, and in the context of the local use, practice and regulatory landscape for these products. Part two also provides an overview and new analysis of international case safety reports for herbal medicines held in VigiBase (the World Health Organization's global database of individual case safety reports, maintained by the Uppsala Monitoring Centre). This book is aimed at pharmacists, doctors, nurses and other health professionals, herbal-medicine practitioners and organisations, herbal medicine and pharmaceutical industry personnel, pharmacovigilance specialists, medicines’ regulators, health and social science researchers and academics, pharmacovigilance and health professional students, and students of herbal and traditional medicine, throughout the world. It is an extremely valuable resource for all individuals whose work touches the intersection between herbal medicines and pharmacovigilance, and it provides both an introduction to the topic and a deeper, comprehensive, contemporary account of the topic.

Endocrine Disruption and Human Health

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Publisher : Academic Press
ISBN 13 : 0128219882
Total Pages : 536 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Endocrine Disruption and Human Health by : Philippa D. Darbre

Download or read book Endocrine Disruption and Human Health written by Philippa D. Darbre and published by Academic Press. This book was released on 2021-09-19 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated with new and expanded chapters, Endocrine Disruption and Human Health, Second Edition provides an introduction to what endocrine disruptors are, the issues surrounding them, the source of these chemicals in the ecosystem and the mechanisms of action and assay systems. Contributions by specialists are included to discuss the varying effects of endocrine disruption on human health, and procedures for risk assessment of endocrine disruptors, and current approaches to their regulation are also covered. With new material on topics such as low-term, low dose mixtures, windows of susceptibility, epigenetics, EDCs effect on the gut microbiome, EDCs in from polluted air and oral exposures, green chemistry, and nanotechnology, the new edition of Endocrine Disruption and Human Health is a valuable and informative text for academic and clinical researchers and other health professionals approaching endocrine disruption and its effects on human health for the first time, graduate students, and advanced undergraduate students. Provides readers with access to a range of information from the basic mechanisms and assays through to cutting-edge research investigating concerns for human health Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations Newly added content on topics like low-term, low dose mixtures, windows of susceptibility to EDCs, EDCs effect on the gut microbiome, green chemistry, and nanotechnology

The Poison Trials

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Publisher : University of Chicago Press
ISBN 13 : 022674499X
Total Pages : 338 pages
Book Rating : 4.2/5 (267 download)

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Book Synopsis The Poison Trials by : Alisha Rankin

Download or read book The Poison Trials written by Alisha Rankin and published by University of Chicago Press. This book was released on 2021-01-22 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1524, Pope Clement VII gave two condemned criminals to his physician to test a promising new antidote. After each convict ate a marzipan cake poisoned with deadly aconite, one of them received the antidote, and lived—the other died in agony. In sixteenth-century Europe, this and more than a dozen other accounts of poison trials were committed to writing. Alisha Rankin tells their little-known story. At a time when poison was widely feared, the urgent need for effective cures provoked intense excitement about new drugs. As doctors created, performed, and evaluated poison trials, they devoted careful attention to method, wrote detailed experimental reports, and engaged with the problem of using human subjects for fatal tests. In reconstructing this history, Rankin reveals how the antidote trials generated extensive engagement with “experimental thinking” long before the great experimental boom of the seventeenth century and investigates how competition with lower-class healers spurred on this trend. The Poison Trials sheds welcome and timely light on the intertwined nature of medical innovations, professional rivalries, and political power.

American Practitioner and News

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Publisher :
ISBN 13 :
Total Pages : 1090 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis American Practitioner and News by :

Download or read book American Practitioner and News written by and published by . This book was released on 1896 with total page 1090 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmaceutical Calculations

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Publisher :
ISBN 13 : 9780812110074
Total Pages : 428 pages
Book Rating : 4.1/5 (1 download)

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Book Synopsis Pharmaceutical Calculations by : Mitchell J. Stoklosa

Download or read book Pharmaceutical Calculations written by Mitchell J. Stoklosa and published by . This book was released on 1986 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The British Homoeopathic Review

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Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis The British Homoeopathic Review by :

Download or read book The British Homoeopathic Review written by and published by . This book was released on 1907 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmacology for Nurses

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Publisher : Jones & Bartlett Learning
ISBN 13 : 1284141985
Total Pages : 570 pages
Book Rating : 4.2/5 (841 download)

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Book Synopsis Pharmacology for Nurses by : Blaine T. Smith

Download or read book Pharmacology for Nurses written by Blaine T. Smith and published by Jones & Bartlett Learning. This book was released on 2018-12-01 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology for Nurses, Second Edition teaches undergraduate nursing students the basic concepts of pharmacology.

Sessional Papers

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Publisher :
ISBN 13 :
Total Pages : 1050 pages
Book Rating : 4.:/5 (36 download)

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Book Synopsis Sessional Papers by : Great Britain. Parliament. House of Commons

Download or read book Sessional Papers written by Great Britain. Parliament. House of Commons and published by . This book was released on 1908 with total page 1050 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Parliamentary Papers

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Publisher :
ISBN 13 :
Total Pages : 1074 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Parliamentary Papers by : Great Britain. Parliament. House of Commons

Download or read book Parliamentary Papers written by Great Britain. Parliament. House of Commons and published by . This book was released on 1908 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Suffering Gene

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Publisher : Zed Books
ISBN 13 : 9781842772850
Total Pages : 268 pages
Book Rating : 4.7/5 (728 download)

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Book Synopsis The Suffering Gene by : Roy Burdon

Download or read book The Suffering Gene written by Roy Burdon and published by Zed Books. This book was released on 2003-05 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer kills one man out of every two, and one woman out of three, in the industrialized countries today. And its incidence, despite all efforts to the contrary, is increasing at one per cent a year. The fact is that some 80 per cent of cancers are likely to be due to environmental factors that could be reduced or even eradicated. This book explains how our genes work, and how they are adversely affected by the modern environment in which we live, whether in the North or the South. The factors include toxic industrial and agricultural chemicals, excessive sunlight ( a result of the hole in the ozone layer), nuclear radiation from power plants and the military, other forms of radiation (mobile phones, electricity transmission systems), food contaminants, atmospheric pollutants (tobacco smoke, car exhaust fumes), and the potential impact of genetic engineering. It explains how the body defends itself from external attack, what happens when these defences are overwhelmed, and the need for much more careful development of new technologies, industrial processes, products and foodstuffs.

Chemical Carcinogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 1617379956
Total Pages : 447 pages
Book Rating : 4.6/5 (173 download)

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Book Synopsis Chemical Carcinogenesis by : Trevor M. Penning

Download or read book Chemical Carcinogenesis written by Trevor M. Penning and published by Springer Science & Business Media. This book was released on 2011-03-03 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.

CDC Yellow Book 2018: Health Information for International Travel

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Publisher : Oxford University Press
ISBN 13 : 0190628634
Total Pages : 672 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis CDC Yellow Book 2018: Health Information for International Travel by : Centers for Disease Control and Prevention CDC

Download or read book CDC Yellow Book 2018: Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.