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Author : KALTER H.
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (985 download)
Download or read book ISSUES AND REVIEWS IN TERATOLOGY [Vol 1 -]. written by KALTER H. and published by . This book was released on 1983 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : H. Kalter
Publisher : Springer Science & Business Media
ISBN 13 : 1461305217
Total Pages : 332 pages
Book Rating : 4.4/5 (613 download)
Download or read book Issues and Reviews in Teratology written by H. Kalter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why Efforts to Expand the Meaning of "Teratogen" Are Unacceptable Disagreement about nomenclature in teratology is not new. Dissent even about the very fabric of the discipline-what congenital malformations consist of-has often been voiced. Time, instead of resolving such diffi culties, has sometimes worsened them. For example, in the past it was agreed that congenital malforma tions are abnormalities of structure present at birth, but differences of opinion concerning where the line between normal and abnormal was to be drawn prevailed. It was obvious that, in order to discover the causes of congenital malformations and cast strategies for their prevention, it would be necessary to have knowledge of the baseline of their frequency, and that this required uniformity of definition of terms. Since malfor mations of primary social concern are those having grave outcomes (and are, paradoxically, also the commonest ones), it is logical that such condi tions were the first consideration of investigators and were the defects whose frequency was considered to comprise the required baseline.
Author : Harold Kalter
Publisher : Springer Science & Business Media
ISBN 13 : 1461573149
Total Pages : 528 pages
Book Rating : 4.4/5 (615 download)
Download or read book Issues and Reviews in Teratology written by Harold Kalter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: A growing sophistication of the American populace about the nature and realities of the impact of the environment on prenatal development was not much in evi dence in 1983. Continuing accusations against Agent Orange and Bendectin high light what must be a deep credulousness and need to blame others for one's bio logical misfortunes. We despair that ignorance and nonaccountability can be dissipated by objective means. But one can only learn and teach and hope. The need to know what causes congenital malformations becomes more imperative as they become the last major holdout, the most unyielding of all the reasons babies still die and are seriously ill. In the aggregate, congenital malfor mations are now the cause of about one-third of the deaths of infants less than one month old and one-fifth of the deaths of those under one year old, up 50% in the last two decades. In the instance of one suspected cause of congenital malformations, maternal insulin-dependent diabetes mellitus, while the perinatal mortality rate of children of such women has gone down greatly since World War II, the fraction of deaths due to congenital malformations has grown correspondingly and is now approach ing 50%. Present-day knowledge of the causes of congenital malformations is most imperfect. A recent authoritative review found that there is understanding to one extent or another of the causation of less than half of all congenital malformations.
Author : H. Kalter
Publisher : Springer Science & Business Media
ISBN 13 : 1461529069
Total Pages : 234 pages
Book Rating : 4.4/5 (615 download)
Download or read book Issues and Reviews in Teratology written by H. Kalter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: ''A valuable resource for those concerned with experimental teratology and risk assessment and those requiring general information about the causes of birth defects. The treatment of these issues is sophisticated, succinct, and logical.'' --- American Scientist, from a review of a previous volume The current volume covers intergenerational factors in pregnancy outcome, the thresholds for developmental toxicants, and four other subjects.
Author : H. Kalter
Publisher : Springer Science & Business Media
ISBN 13 : 1461525128
Total Pages : 293 pages
Book Rating : 4.4/5 (615 download)
Download or read book Issues and Reviews in Teratology written by H. Kalter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: From a review of an earlier volume: 'Both the experimental and the human aspects of teratology are presented in this comprehensive text by a stellar group of internationally recognized scientists and clinicians....A valuable resource for those concerned with experimental teratology and risk assessment and those requiring general information about the causes of birth defects. The treatment of these issues is sophisticated, succinct, and logical.'-American Scientist
Author : Harold Kalter
Publisher : Springer Science & Business Media
ISBN 13 : 1461573114
Total Pages : 368 pages
Book Rating : 4.4/5 (615 download)
Download or read book Issues and Reviews in Teratology written by Harold Kalter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teratology is at once among the oldest and youngest of human preoccupations. Coincident with man's first observations of the stars were his recordings of human and animal deformities. But, such aberrancies must have occurred even earlier, for although it is one of those things-like evolution-that cannot be proven, it is nevertheless indisputable that dysmorphogenesis must have occurred from the time complex forms of life first arose on our planet; and that from the beginnings of human awareness our species was conscious of such happenings. From the earliest recordings of this fascination with the form and meaning of abnormality a tortuous but continuous line extends to modern struggles to understand and control these manifestations. And now, after long occupying an honorable but peripheral place in the halls of philosophical and scientific pursuits, teratology has quite suddenly come to take a prominent position at the hub of a complex crossroads of human concerns. This shift in its fortune has taken several forms. Fetal maldevelopment has become the concern of environmentalists, activists of various persuasions, indus trial organizations, government agencies, ethicists, parents-i. e. , individuals and groups whose actions are impelled by apprehension. Such motives are of course not without basis; the trauma of thalidomide left a scar yet raw. For still others clinicians, academics, experimentalists-the upsurge in the interest in fetal mal development is at a different level, and their pursuits are broad, taking external agents as but one of the causes of defective development.
Author : H. Kalter
Publisher : Springer
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.E/5 ( download)
Download or read book Issues and Reviews in Teratology written by H. Kalter and published by Springer. This book was released on 1990-02-28 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why Efforts to Expand the Meaning of "Teratogen" Are Unacceptable Disagreement about nomenclature in teratology is not new. Dissent even about the very fabric of the discipline-what congenital malformations consist of-has often been voiced. Time, instead of resolving such diffi culties, has sometimes worsened them. For example, in the past it was agreed that congenital malforma tions are abnormalities of structure present at birth, but differences of opinion concerning where the line between normal and abnormal was to be drawn prevailed. It was obvious that, in order to discover the causes of congenital malformations and cast strategies for their prevention, it would be necessary to have knowledge of the baseline of their frequency, and that this required uniformity of definition of terms. Since malfor mations of primary social concern are those having grave outcomes (and are, paradoxically, also the commonest ones), it is logical that such condi tions were the first consideration of investigators and were the defects whose frequency was considered to comprise the required baseline.
Author : Harold Kalter
Publisher :
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.:/5 (292 download)
Download or read book Issues and Reviews in Teratology written by Harold Kalter and published by . This book was released on 1993 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Harold Kalter
Publisher : Springer Science & Business Media
ISBN 13 : 1461324955
Total Pages : 309 pages
Book Rating : 4.4/5 (613 download)
Download or read book Issues and Reviews in Teratology written by Harold Kalter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is still no clear understanding of what causes the great majority of human congenital malformations. And since in most sorts of human disease and pathology that yet prevail prevention usually awaits understanding of cause, it is generally thought that the same is true of developmental aberrations. But is this true? For the relatively few congenital malformations whose causes are primarily environmental, it is plain that their discovery has enabled prevention, but not nec essarily immediately. It took a generation from the time of the discovery that maternal rubella was teratogenic to learn how to immunize against it. Much debate occurred before it was appreciated that thalidomide was a teratogen, and only its removal from the pharmacist's shelf and the end of the epidemic of limb defects attributed to the drug overcame the last doubts. For other proven environmental teratogens doubts and difficulties still con tinue. The claimed prevalence of fetal genital distortions due to female sex hor mones may have been exaggerated. Some potentially teratogenic therapeutic drugs, like anticoagulants, anticonvulsants, and anticancer chemicals, are still pre scribed despite this danger because of their benefits to pregnant women. For those congenital malformations whose basis is predominantly genetic or chromosomal it is different, however. Prevention has not been achieved by the discovery of such causes, as dramatic and revolutionary as some of them have been, except in the questionable sense of interference with reproduction by genetic coun seling or prenatal elimination. But this has not inhibited the romanticists.
Author : KALTER H.
Publisher :
ISBN 13 : 9781461573128
Total Pages : 376 pages
Book Rating : 4.5/5 (731 download)
Download or read book Issues and Reviews in Teratology written by KALTER H. and published by . This book was released on 1983-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Harold Kalter
Publisher : Springer Science & Business Media
ISBN 13 : 9048188202
Total Pages : 266 pages
Book Rating : 4.0/5 (481 download)
Download or read book Teratology in the Twentieth Century Plus Ten written by Harold Kalter and published by Springer Science & Business Media. This book was released on 2010-07-28 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serious congenital malformations are a major contributor to the infant death rate worldwide. Their nonhereditary causes are multiple and complex, and include infectious and metabolic dangers, disease medication, nutritional inadequacy, medicinal products, environmental agents and pollutants, among them. The cause of many however is still unknown. The wide range of these causes makes the defects of interest to those of a wide range of medical and investigatory backgrounds, especialy clinicians, fundamental scientists, and environmentalists.
Author : H. Kalter
Publisher : Elsevier
ISBN 13 : 0080542352
Total Pages : 166 pages
Book Rating : 4.0/5 (85 download)
Download or read book Teratology in the Twentieth Century written by H. Kalter and published by Elsevier. This book was released on 2003-06-06 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment.
Author : Thomas H. Shepard
Publisher : JHU Press
ISBN 13 : 9780801879531
Total Pages : 564 pages
Book Rating : 4.8/5 (795 download)
Download or read book Catalog of Teratogenic Agents written by Thomas H. Shepard and published by JHU Press. This book was released on 2004 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Links information on experimental teratogenic agents with the congenital defects in human beings.
Author : Thomas C. Jones
Publisher : Springer Science & Business Media
ISBN 13 : 3642849067
Total Pages : 221 pages
Book Rating : 4.6/5 (428 download)
Download or read book Nonhuman Primates I written by Thomas C. Jones and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmonize toxicologic testing, to advance a more uniform interpreta tion of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scientists. The Mo nographs on the Pathology of Laboratory Animals are de signed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others con cerned with evaluating toxicity and carcinogenicity stu dies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors -strengthens our expectations that understanding and cooperation will be improved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on Nonhuman Primates, is the eleventh volume of a set pre pared under the sponsorship of the International Life Sciences Institute (ILSI).
Author : National Institute for Occupational Safety and Health
Publisher :
ISBN 13 :
Total Pages : 40 pages
Book Rating : 4.3/5 (91 download)
Download or read book Proposed National Strategy for the Prevention of Disorders of Reproduction written by National Institute for Occupational Safety and Health and published by . This book was released on 1989 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : DIANE Publishing
ISBN 13 : 9780788105210
Total Pages : 370 pages
Book Rating : 4.1/5 (52 download)
Download or read book Catalog of Federal Domestic Assistance, 1993 written by and published by DIANE Publishing. This book was released on 1994-06 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shows how you can qualify for the billions of Federal dollars available through grants from the U.S. Gov't. A comprehensive listing of over 1,200 Gov't. grants & assistance programs for practically every conceivable area from: adult education to disease research, from community development to environmental programs, & more. 4 indexes. Each grant listing includes: program objectives & goals; types of assistance offered; eligibility requirements; examples of funded projects; & criteria for selecting proposals.
Author :
Publisher :
ISBN 13 :
Total Pages : 182 pages
Book Rating : 4.:/5 (31 download)
Download or read book Reproductive Hazards in the Workplace written by and published by . This book was released on 1994 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
