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Author : Peter L. Pedersen
Publisher :
ISBN 13 :
Total Pages : 4 pages
Book Rating : 4.:/5 (793 download)
Download or read book Ion Motive ATPases. II. Energy Coupling and Work Outputs written by Peter L. Pedersen and published by . This book was released on 1987 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sajal Chakraborti
Publisher : Springer
ISBN 13 : 3319247808
Total Pages : 582 pages
Book Rating : 4.3/5 (192 download)
Download or read book Regulation of Ca2+-ATPases,V-ATPases and F-ATPases written by Sajal Chakraborti and published by Springer. This book was released on 2015-12-10 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biological membranes of cellular organization enfold an important group of membrane proteins called the ATPases, which are not only versatile in maintaining chemical gradient and electrical potential across the membrane but also bring metabolites necessary for cell metabolism and drive out toxins, waste products and solutes that otherwise can curb cell functions. ATPases are distributed virtually in all live forms starting from unicellular to multicellular and also in viruses. There are different types of ATPases, which differ in function and structure and in the type of ions they transport. The three main types of the ion pump ATPase family are: (i) P-type ATPases that transport different ions across membranes and Ca2+ATPases belongs to this catagory (ii) F-type ATPase in mitochondria, chloroplasts and bacterial plasma membranes produce ATP using the proton gradient; and (iii) V-type ATPase catalyzes ATP hydrolysis to transport solutes and maintains acidic pH in organelles like lysosomes. Genetic defects in either of the ATPases cause several diseases and a number of researches have demonstrated the involvement of the members of ATPases in the cell pathology and diseases, thereby penetrating exciting new areas of our understanding. In this book, the authors summarize recent knowledge about the molecular mechanisms associated with Ca2+-ATPase, V-ATPase and F-ATPase in intracellular and extracellular Ca2+ transport, mitochondrial ATP synthase, vesicular H+ transport, and lysosomal pH regulation. This book thereby bridges the gap between fundamental research and biomedical and pharmaceutical applications. The book provides an informative resource to improve ATPase research and modern therapeutic approaches toward different life threatening diseases that are associated with dysregulation of the ATPases.
Author : A.G. Lee
Publisher : Elsevier
ISBN 13 : 0080527701
Total Pages : 441 pages
Book Rating : 4.0/5 (85 download)
Download or read book ATPases written by A.G. Lee and published by Elsevier. This book was released on 1996-12-17 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 5 of Biomembranes covers an important group of membrane proteins, the ATPases. The P-type ATPases couple the hydrolysis of ATP to the movement of ions across a membrane and are characterized by the formation of a phosphoyrlated intermediate. Included are the plasma membrane and muscle sarcoplasmic reticulum Ca2+ -ATPases, the (Na+ -K+) -ATPase, the gastric (H+ -K+) -ATPase, the plasma membrane H+ -ATPase of fungi and plants, the Mg2+ - transport ATPase, the Salmonella typhimurium, and the K+ -ATPase of Escherichia coli, KdpB. The other important classes of ATPase in eukaryotic systems are the vacuolar H+ -ATPases and the F0F1 ATP synthase, and, in bacteria, the anion-translocating ATPases, responsible for resistance to arsenicals and antimonials, and the (Na+ -Mg2+) -ATPase of Acholeplasma. Finally, eukaryotic systems contain a variety of ectonucleotidases important, for example, in hydrolysis of extracellular ATP released as a cotransmitter from cholinergic and adrenergic nerve terminals. Volume 5 of Biomembranes explores structure-function relationships for these mebrane-bound ATPases.
Author : Edward Bittar
Publisher : Elsevier
ISBN 13 : 0080528740
Total Pages : 415 pages
Book Rating : 4.0/5 (85 download)
Download or read book Cell Chemistry and Physiology: Part II written by Edward Bittar and published by Elsevier. This book was released on 1996-05-14 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume illustrates the extent to which the traditional distinction between biochemical and physiological processes is being obliterated by molecular biology. It can hardly be doubted that the revolution in cell and molecular biology is leading to core knowledge that provides an outline of the integrative and reductionist approach. We view this as the beginning of a new era, that of the integration of learning. As in the preceding volumes, the choice of topics has been deliberate not only because of the need to keep the volume within reasonable bounds but also because of the need to avoid information over-load. Several relevant topics are dealt with in other modules; for example, the role of G proteins in transmembrane signalling is covered in the Membranes and Cell Signalling module (i.e., Volume 7). Omissions are of course inevitable but they are minor. A case in point is the subject of phosphatases, the treatment of which does not take into account calcineurin. One of the key functions of this Ca2+ -activated protein phosphatase that is also regulated by calmodulin is to desphosphorylate voltage-dependent Ca2+ channels. The mere recognition of such omissions before or after consulting textbooks and journals should be a spur to a more complete discussion by the student of the subject in a small group teaching setting.
Author : Nathan Nelson
Publisher : Springer Science & Business Media
ISBN 13 : 3662222655
Total Pages : 237 pages
Book Rating : 4.6/5 (622 download)
Download or read book Organellar Proton-ATPases written by Nathan Nelson and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE WORLD OF PROTON PUMPS Nathan Nelson uite frequently an observer looks at a life phenomenon and asks ~himself why nature took this route out of several other available mec anisms. In order to understand this challenge he may first try to reconstruct the evolution of the process taking into account the main driving forces that were assumed to exist during the last 3. 5 billion years on earth. Now we know that the electrochemical gradient of protons is the universal high-energy intermediate produced and uti lized by every living cell in nature. This high energy intermediate is an expression of different concentrations of active protons in the two faces of biological membranes. Why then did nature elect to utilize a pre dominantly electrochemical gradient of protons and no other ion? The answer to this question may lie in the environment in which the first living creatures evolved. Some of them may have been challenged by an acidic environment that lowered their internal pH (by a proton leak through their membranes) to lethal levels. To counteract these inci dents proton pumps evolved. Two independent systems were devel oped. One was a proton pump coupled to energetically downhill vectorial electron transport across membranes and the second was an ATP-dependent proton pump. Both of them pump protons outward from the cells generating an electrochemical gradient of protons.
Author : Ernst-Georg Krause
Publisher : Springer Science & Business Media
ISBN 13 : 1461312795
Total Pages : 313 pages
Book Rating : 4.4/5 (613 download)
Download or read book Biochemical Mechanisms in Heart Function written by Ernst-Georg Krause and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special issue of Molecular and Cellular Biochemistry good source of information in this regard. contains original research papers as well as invited reviews We wish to thank all of the contributors for their help and dedicated, on the occasion of the 40th anniversary of the in cooperation. We also wish to thank Mrs. Verona Kuhle for auguration of the Heart Research Group in Beriin-Buch that her secretarial help. We are grateful to Dr. Naranjan S. Dhalla, today forms a part there ofthe Max Delbriick Center for Mo Editor-in-Chief of Molecular and Cellular Biochemistry for his lecular Medicine, to Professor Albert Wollenberger, founder interest and encouragement, and for agreeing to publish this of the Heart Research Group and for 21 years its head. issue in honor of Albert Wollenberger. The papers in this issue are written by researchers work ing in the field of cardiovascular research who together with ERNST-GEORG KRAUSE and ROLAND VETTER Albert Wollenberger share the belief that an integrative ap Max Delbriick Center for Molecular Medicine plication of advances in molecular and cellular biology will Robert-Rossle-StraBe 10 lead to new concepts for treatment and prevention of cardio 13122 Beriin-Buch vascular diseases. We hope that this special will serve as a Gennany ALBERT WOLLENBERGER, Professor, Ph. D. (Harvard), Dr. Sc. Med. (Berlin) The dedication is accorded to Prof.
Author : H.R. Petty
Publisher : Springer Science & Business Media
ISBN 13 : 9780306444296
Total Pages : 432 pages
Book Rating : 4.4/5 (442 download)
Download or read book Molecular Biology of Membranes written by H.R. Petty and published by Springer Science & Business Media. This book was released on 1993-05-31 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This well-organized, 'user friendly', and profusely illustrated work fills the need for an up-to-date textbook on the structure and function of biological membranes. In addition to the traditional topics covered in membrane biology courses, it discusses recent findings provided by cDNA cloning and X-ray diffraction to furnish the advanced undergraduate and graduate student with the most current, practical classroom resource available.
Author : Joachim Krebs
Publisher : Springer
ISBN 13 : 3319558587
Total Pages : 409 pages
Book Rating : 4.3/5 (195 download)
Download or read book Membrane Dynamics and Calcium Signaling written by Joachim Krebs and published by Springer. This book was released on 2018-03-28 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the newest discoveries on calcium signaling happening at the cellular and intracellular membranes, often exerted in so called microdomains. Calcium entry and release, its interaction with proteins and resulting events on proteins and organelles are comprehensively depicted by leading experts in the field. Knowledge about details of these highly dynamic processes rapidly increased in recent years, the book therefore provides a timely summary on the processes of calcium signaling and related membrane dynamics; it is aimed at students and researchers in biochemistry and cell biology.
Author : Zeno Simon
Publisher : CRC Press
ISBN 13 : 9780849353987
Total Pages : 356 pages
Book Rating : 4.3/5 (539 download)
Download or read book Specific Interaction and Biological Recognition Processes written by Zeno Simon and published by CRC Press. This book was released on 1993-06-16 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specific Interaction and Biological Recognition Processes is devoted to two major aspects of biological processes: specificity in biological recognition and the recognition processes themselves. Topics covered in specificity include the theoretical basis for specificity in biological recognition; the thermodynamic and chemical equilibrium background; and consideration of the relationship between size of combining sites and specificity. The use of semi-emperical potentials for calculating interaction energies and the potential of quantum chemistry methods for calculating receptor-effector affinities are also discussed. The various recognition processes described include DNA replication, transcription, translation, enzymatic reactions, transmembrane transport processes, mechanisms of action of hormones and other chemical messengers, and self-nonself recognition in immunology. Specific Interaction and Biological Recognition Processes will be a useful reference for molecular biologists, biochemists, enzymologists, immunologists oncologists, pharmaceutical researchers, and others interested in the topic.
Author : Edward Bittar
Publisher : Elsevier
ISBN 13 : 0080528732
Total Pages : 361 pages
Book Rating : 4.0/5 (85 download)
Download or read book Cell Chemistry and Physiology: Part III written by Edward Bittar and published by Elsevier. This book was released on 1996-06-17 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first section of this volume consists of five chapters to the nature of membrane transport systems. A chapter on secondary active glucose transport has been omitted because this topic is slated to appear in the Nephrobiology module. Chapter 6 deals with oxidase control of plasma membrane proton transport, while chapter 7 addresses the question of how cell volume is regulated. Although we chose not to have a separate chapter covering additional co-transport systems namely, Na+ -K+ -2CI-, KCI, -HCO-3, as well as CI- -HCO-3 exchange and K+ and CI- movements through channels, the role of each in cell volume regulation is emphasized in Chapter 7. Instead of devoting an entire section to the thermodynamics of metabolism, we thought it desirable to have the subjects of medical imaging and NMR of cell metabolism discussed in some detail in two chapters. These are followed by a chapter on the thermodynamic instrument - the calorimeter. Calrimetry allows the measurement of net changes of heat in cells, tissues, organs and whole body. As will be recognized, heat dissipation does not arise only from chemical reactions but also from interactions between macromolecules and conformational changes in protein complexes and mass Ca2+ movement such as that occurring in contracting skeletal muscle. The last chapter provides an account of equilibrium and non-equilibrium thermodynamics and the enthalpy balance method. It reveals that calometric measurements are useful in studies of clinical and toxicological problems.
Author : Christer Larsson
Publisher : Springer Science & Business Media
ISBN 13 : 3642745229
Total Pages : 427 pages
Book Rating : 4.6/5 (427 download)
Download or read book The Plant Plasma Membrane written by Christer Larsson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The plasma membrane forms the living barrier between the cell and its surroundings. For this reason it has a wide range of important functions related to the regulation of the composition of the cell interior and to com munication with the cell exterior. The plasma membrane has therefore attracted a lot of research interest. Until the early 1970's it was only pos sible to study the plasma membrane in situ, its structure e. g. by electron microscopy and its function e. g. by uptake of radioactively labeled com pounds into the intact cell or tissue. The first isolation of plant protoplasts by enzymatic digestion of the cell wall in the early 1970's was an important step forward in that it provided direct access to the outer surface of the plasma membrane. More importantly, T. K. Hodges and R. J. Leonard in 1972 published the description of a method by which a fraction enriched in plasma membranes could be isolated from plant tissues using sucrose gradient centrifugation. As a result, the 1970's saw a leap forward in our understanding of the structurc and function of the plasma membrane. In 1981, S. Widell and C. Larsson published the first of a series of papers in which plasma membrane vesicles of high yield and purity were isolated from a wide range of plant tissues using aqueous polymer two-phase parti tioning.
Author : Kenneth Simkiss
Publisher : Elsevier
ISBN 13 : 0080925847
Total Pages : 352 pages
Book Rating : 4.0/5 (89 download)
Download or read book Biomineralization written by Kenneth Simkiss and published by Elsevier. This book was released on 2012-12-02 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomineralization is the process that produces the skeletons, shells, and teeth of most animals. It is also involved in magnetic orientation, gravity detection, and the storing of ions. This book compares a diverse number of systems, including mineral deposition of invertebrates, vertebrates, algae, and microorganisms. Emphasis is placed on the systems responsible for converting ions to minerals and the mechanisms and control of mineral form.
Author : William A. Cramer
Publisher : Springer Science & Business Media
ISBN 13 : 1461232201
Total Pages : 553 pages
Book Rating : 4.4/5 (612 download)
Download or read book Energy Transduction in Biological Membranes written by William A. Cramer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Energy Transduction in Biological Membranes was primarily designed for graduate courses in bioenergetics. Not only does it discuss basic principles and concepts central to modern membrane biochemistry, biophysics and molecular biology, but also (1) the components and pathways for electron transport and hydrogen ion translocation, and (2) the utilization of electrochemical ion gradients. The book is unique in presenting a comparative treatment of respiratory and photosynthetic energy transduction, and in using protein sequence data coupled with physical concepts to discuss the mechanisms of energy transducing proteins.
Author : Marc Solioz
Publisher : Springer
ISBN 13 : 3319944398
Total Pages : 88 pages
Book Rating : 4.3/5 (199 download)
Download or read book Copper and Bacteria written by Marc Solioz and published by Springer. This book was released on 2018-06-23 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades, great progress has been made in the understanding of copper as a bioelement. The book summarizes the current knowledge of copper toxicity, homeostasis and resistance in bacteria, in which proteins like copper ATPases, copper chaperones and copper-responsive regulators of gene expression play major roles. The author also discusses the metallation of cuproenzymes. The evolution of the use of copper by cells and of copper-homeostatic proteins are is also considered in this Brief.
Author : Roland Vetter
Publisher : Springer Science & Business Media
ISBN 13 : 1461312892
Total Pages : 334 pages
Book Rating : 4.4/5 (613 download)
Download or read book Biochemical Regulation of Myocardium written by Roland Vetter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special issue of Molecular and Cellular Biochemistry contains original research papers as well as invited reviews dedi cated, on the occasion of the 40th anniversary of the inauguration of the Heart Research Group in Berlin-Buch that today forms a part there of the Max Delbriick Center for Molecular Medicine, to Professor Albert Wollenberger, founder of the Heart Research Group and for 21 years its head. The papers in this issue are written by researchers working in the field of cardiovascular research who together with Albert Wollenberger share the belief that an integrative application of advances in molecular and cellular biology will lead to new concepts for treatment and prevention of cardiovascular diseases. We hope that this special will serve as a good source of information in this regard. We wish to thank all of the contributors for their help and cooperation. We also wish to thank Mrs. Verona Kuhle for her secretarial help. We are grateful to Dr. Naranjan S. Dhalla, Editor-in-Chief of Molecular and Cellular Biochemistry for his interest and encouragement, and for agreeing to publish this issue in honor of Albert Wollenberger. ROLAND VETTER and ERNST -GEORG KRAUSE Max Delbriick Center for Molecular Medicine, Robert-Rossle-StraBe 10, 13122 Berlin-Buch, Germany PART I CARDIAC DEVELOPMENT AND REGULATION Molecular and Cellular Biochemistry 163/164: 5-11, 1996. © 1996 Kluwer Academic Publishers.
Author : Peter Läuger
Publisher : Sinauer Associates, Incorporated
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.3/5 (91 download)
Download or read book Electrogenic Ion Pumps written by Peter Läuger and published by Sinauer Associates, Incorporated. This book was released on 1991 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrogenic ion pumps convert chemical, reduction-oxidation, or light energy- into ion concentration differences across all living cells. They are the engines that run cells. In this text, Dr Lunger develops the principles of physical chemistry required to understand the functions of these macromolecules.
Author : Arturo Leone
Publisher : Springer Science & Business Media
ISBN 13 : 1461548594
Total Pages : 276 pages
Book Rating : 4.4/5 (615 download)
Download or read book Copper Transport and Its Disorders written by Arturo Leone and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of presentations at the first meeting devoted to the mo lecular and cellular biology of copper transport. When we first considered the possible program for the meeting, we felt that a forum to integrate the recent advances in molecular understanding of copper transport with the older knowledge of copper metabolism was needed. In addition we wished to have a strong emphasis on the diseases of copper includ ing the genetic diseases, Menkes and Wilson, and other possible health aspects of this met al seen from a molecular perspective. Overall we were very happy with the success of the meeting, and most participants were very enthusiastic. Unfortunately we were not able to obtain manuscripts from every contributor, but the selection in this book covers most of the topics discussed. The history of biological research into copper dates from the latter half of the last century when the presence of copper as a component of living systems was first noted, but it was not until the 1920s that the essential role of copper was first recognized. l. S. McHargue found that plants and animals needed copper for optimal growth and health and proposed that copper was needed for life (McHargue, 1925). Other groups soon confirmed these observations in plants. In animals the requirement of copper for hematopoiesis was discovered in 1928 (Hart et aI.
