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Author : Susan Joy Hoshaw
Publisher :
ISBN 13 :
Total Pages : 254 pages
Book Rating : 4.3/5 (91 download)
Download or read book Investigation of Bone Modeling and Remodeling at a Loaded Bone-implant Interface written by Susan Joy Hoshaw and published by . This book was released on 1992 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Andy H. Choi
Publisher : Springer Nature
ISBN 13 : 9819914256
Total Pages : 103 pages
Book Rating : 4.8/5 (199 download)
Download or read book Bone Remodeling and Osseointegration of Implants written by Andy H. Choi and published by Springer Nature. This book was released on 2023-05-10 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an insight into the latest advances in bone fracture healing and remodeling algorithm and their incorporation into patient-specific finite element models and the use of machine learning and artificial intelligence to predict the bone regeneration and osseointegration process with a certain degree of accuracy. It also examines the applications of numerical models to simulate the fracture healing process, which may prove to be advantageous in determining the optimal mechanical-based treatment or reconstruction after an accident or illness. This book is aimed at medical and dental professionals who are involved in implantology and tissue engineering such as dentists, oral and maxillofacial surgeons, orthopedic surgeons, students, and researchers.
Author : Rabeb Ben Kahla
Publisher : Academic Press
ISBN 13 : 0323902057
Total Pages : 238 pages
Book Rating : 4.3/5 (239 download)
Download or read book Bone Remodeling Process written by Rabeb Ben Kahla and published by Academic Press. This book was released on 2021-08-14 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation. Each chapter covers a core topic in bone biomechanics Provides a multidisciplinary view that effectively links orthopaedics, cellular biology, mechanics, and computer simulation Draws an overall image about bone biology and cell interactions, for identifying cell populations that are crucial for the remodeling process
Author : Adriano Piattelli
Publisher : Woodhead Publishing
ISBN 13 : 0081002882
Total Pages : 286 pages
Book Rating : 4.0/5 (81 download)
Download or read book Bone Response to Dental Implant Materials written by Adriano Piattelli and published by Woodhead Publishing. This book was released on 2016-10-27 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Response to Dental Implant Materials examines the oral environment and the challenges associated with dental biomaterials. Understanding different in vivo and in vitro responses is essential for engineers to successfully design and tailor implant materials which will withstand the different challenges of this unique environment. This comprehensive book reviews the fundamentals of bone responses in a variety of implant materials and presents strategies to tailor and control them. Presents a specific focus on the development and use of biomaterials in the oral environment Discusses the basic science of the dental interface and its clinical applications Contains important coverage on the monitoring and analysis of the dental implant interface
Author : Mehdi Amirhosseini
Publisher : Linköping University Electronic Press
ISBN 13 : 9176852385
Total Pages : 41 pages
Book Rating : 4.1/5 (768 download)
Download or read book Aseptic Loosening of Orthopedic Implants written by Mehdi Amirhosseini and published by Linköping University Electronic Press. This book was released on 2019-05-24 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aseptic loosening is the main cause of failure of orthopedic prostheses. With no pharmaceuticals to prevent or mitigate periprosthetic bone degradation, a surgery to replace the loose implant with a new one is the only choice to restore patients’ function. Most studies on mechanisms for aseptic loosening investigate wear debris particle-induced osteolysis. However, pathological loading conditions around unstable implants can also trigger osteoclast differentiation and bone loss. In the first study, global gene expression changes induced by mechanical instability of implants, and by titanium particles were compared in a validated rat model for aseptic loosening. Microarray analysis showed that similar signaling pathways and gene expression patterns are involved in particle- and instability-induced periprosthetic osteolysis with an early onset innate immune response as a hallmark of osteolysis induced by mechanical instability. Further, effects of potential therapeutics on restriction of excessive osteoclast differentiation were evaluated. Wnt signaling pathway is known to regulate bone remodeling. In the second study, effects of inactivation of glycogen synthase kinase 3 beta (GSK-3?), a negative regulator of canonical Wnt signaling, on instability-induced periprosthetic osteolysis were examined using our rat model for aseptic loosening. Inhibition of GSK-3? led to a decrease in osteoclast numbers in the periprosthetic bone tissue exposed to mechanical instability while osteoblast perimeter showed an increase. This was accompanied by higher bone volume fraction (BV/TV) in animals treated with the GSK-3? inhibitor. In the third study, potential beneficial effects of two selective inhibitors of cyclindependent kinase 8/19 (CDK8/19) on bone tissue were evaluated. CDK8/19 is a Mediator complex-associated transcriptional regulator involved in several signaling pathways. CDK8/19 inhibitors, mainly under investigation as treatments for tumors, are reported to enhance osteoblast differentiation and bone formation. We show in this study, for the first time, that inhibition of CDK8/19 led to marked suppression of osteoclast differentiation from bone marrow macrophages in vitro through disruption of the RANK signaling. In mouse primary osteoblasts downregulation of osteopontin mRNA, a negative regulator of mineralization, together with increased alkaline phosphatase activity and calcium deposition indicated that osteoblast mineralization was promoted by CDK8/19 inhibition. Moreover, local administration of a CDK8/19 inhibitor promoted cancellous bone regeneration in a rat model for bone healing. These studies contribute to better understanding of mechanisms behind mechanical instability-induced periprosthetic osteolysis and propose potential therapeutics to restrict bone loss with effects on both osteoclasts and osteoblasts.
Author : Qing-Hua Qin
Publisher : CRC Press
ISBN 13 : 1466564164
Total Pages : 323 pages
Book Rating : 4.4/5 (665 download)
Download or read book Mechanics of Cellular Bone Remodeling written by Qing-Hua Qin and published by CRC Press. This book was released on 2013-01-08 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on bone remodeling has resulted in much new information and has led to improvements in design and biomedical practices. Mechanics of Cellular Bone Remodeling: Coupled Thermal, Electrical, and Mechanical Field Effects presents a unified exploration of recent advances, giving readers a sound understanding of bone remodeling and its mathematical representation. Beginning with a description of the basic concept of bone remodeling from a mathematical point of view, the book details the development of each of the techniques and ideas. From there it progresses to the derivation and construction of multifield and cellular bone remodeling and shows how they arise naturally in response to external multifield loads. Topics include: Fundamental concepts and basic formulations for bone remodeling Applications of formulations to multifield internal bone remodeling of inhomogeneous long cylindrical bone Theory and solution of multifield surface bone remodeling A hypothetical regulation mechanism on growth factors for bone modeling and remodeling under multifield loading The RANK–RANKL–OPG pathway and formulation for analyzing the bone remodeling process A model of bone cell population dynamics for cortical bone remodeling under mechanical and pulsed electromagnetic stimulus Recent developments in experiments with bone materials Readers will benefit from the thorough coverage of general principles for each topic, followed by detailed mathematical derivations and worked examples, as well as tables and figures where appropriate. The book not only serves as a reliable reference but is also destined to attract interested readers and researchers to a field that offers fascinating and technologically important challenges.
Author : Peter Pivonka
Publisher : Springer
ISBN 13 : 3319588451
Total Pages : 295 pages
Book Rating : 4.3/5 (195 download)
Download or read book Multiscale Mechanobiology of Bone Remodeling and Adaptation written by Peter Pivonka and published by Springer. This book was released on 2017-06-20 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.
Author : Jona J. Sela
Publisher : Springer Science & Business Media
ISBN 13 : 146142058X
Total Pages : 161 pages
Book Rating : 4.4/5 (614 download)
Download or read book Principles of Bone Regeneration written by Jona J. Sela and published by Springer Science & Business Media. This book was released on 2012-03-13 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bone Regeneration is a timely publication that addresses the modern aspects of bone healing and repair. This exciting new volume details the convergence of the different experimental and clinical approaches designed for the study and treatment of bone healing in its diverse forms and under varying conditions. Bone healing is affected by a multitude of genetic, environmental, mechanical, cellular and endocrine variables which eventually lead to changes in gene expression that enhance the guided action of osteoblasts (and chondroblasts) to lay down bone that restores, or even improves, the skeletal load bearing capacity. Recent breakthroughs in understanding the regulatory aspects of bone formation and resorption, in both research and clinical arenas offer new modalities to induce, enhances and guide repair processes in bone for the benefit of millions of patients with conditions such as nonunion fractures, critical size defects, orthodontic tooth movement, periodontal bone loss, intraosseous implants and deformed bones.
Author : Jorge Belinha
Publisher : Springer Nature
ISBN 13 : 3030375412
Total Pages : 249 pages
Book Rating : 4.0/5 (33 download)
Download or read book The Computational Mechanics of Bone Tissue written by Jorge Belinha and published by Springer Nature. This book was released on 2020-02-11 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a timely snapshot of computational methods applied to the study of bone tissue. The bone, a living tissue undergoing constant changes, responds to chemical and mechanical stimuli in order to maximize its mechanical performance. Merging perspectives from the biomedical and the engineering science fields, the book offers some insights into the overall behavior of this complex biological tissue. It covers three main areas: biological characterization of bone tissue, bone remodeling algorithms, and numerical simulation of bone tissue and adjacent structures. Written by clinicians and researchers, and including both review chapters and original research, the book offers an overview of the state-of-the-art in computational mechanics of bone tissue, as well as a good balance of biological and engineering methods for bone tissue analysis. An up-to-date resource for mechanical and biomedical engineers seeking new ideas, it also promotes interdisciplinary collaborations to advance research in the field.
Author : Katharina Immel
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (135 download)
Download or read book Numerical Modeling of the Adhesive Contact at the Bone-implant Interface written by Katharina Immel and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cementless implants have become more and more common for joint replacement anddental surgery. Initial stability is obtained during the surgery through a press fit processin the host bone, while long-term stability is obtained by bone growing around and intothe porous surface of the implant, a process called osseointegration. As debonding ofthe bone-implant interface due to aseptic loosening and insufficient osseointegration stilloccur and may have dramatic consequences, predicting implant stability and failure isone of the major goals in modern implant research.This work presents different 3D FE modeling approaches to model contact and initialand long-term stability of cementless implants using the example of a cylindrical implantand an acetabular cup implant (ACI).First, an approach to assess the initial stability of an ACI considering a realisticgeometry of a patient's hip, based on Coulomb's friction contact and standard FE, ispresented. The influence of different patient and implant-specific parameters is analyzedin order to determine optimal stability for different configurations and thus obtain theoptimal combination of the implant's surface roughness and the press-fit, based on apatient's bone quality.Second, a phenomenological model for the frictional contact behavior of debondingosseointegrated implants is developed. The classical Coulomb's law is extended froma constant to a varying friction coefficient, that models the transition from an unbroken(osseointegrated) to a broken (debonded) state, based on a state variable depending on thedeformation of the bone-implant interface. Thus, this model can account for the highertangential forces observed in osseointegrated implants compared to unbonded implants. Inaddition, a NURBS-enrichment approach for 3D contact elements is used for an efficientmodeling of the geometries and their contact. This model is applied to the torsionaldebonding of CSI and the results are compared to experimental data and to a previousanalytical model.Third, the modified Coulomb's law model is extended in normal direction consideringa cohesive zone model, to account for debonding in normal direction and allow for adhesivefriction. This model is applied to simulate secondary stability and debonding ofan ACI in different removal tests, and to determine the relevance of osseointegration andbiomechanical factors for long-term stability. The results are compared with the purelytangential model to identify the relevance of normal adhesion in the debonding of ACI.Last, two simple evolution laws for osseointegration based on initial stability is presentedto account for realistic and time-dependent osseointegration.Due to their generality, all models presented herein can be applied to all kinds of endosseousimplants or imperfectly bonded interfaces in general. Furthermore, the modelscan be coupled with remodeling algorithms or realistic loading data, to make simulationsand prognoses for the whole life cycle of an implant from the surgery, through bone remodelingand osseointegration, to long-term stability under cyclic loading.
Author : Hugh U. Cameron
Publisher : St. Louis ; Toronto : Moseby
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.3/5 (91 download)
Download or read book Bone Implant Interface written by Hugh U. Cameron and published by St. Louis ; Toronto : Moseby. This book was released on 1994 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jeffrey O. Hollinger
Publisher : CRC Press
ISBN 13 : 1135501912
Total Pages : 500 pages
Book Rating : 4.1/5 (355 download)
Download or read book Bone Tissue Engineering written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2004-10-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t
Author : Kangning Su
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (125 download)
Download or read book Imaging-based Numerical Study of Biomechanics and Bone Density Distribution in Human Alveolar Bone written by Kangning Su and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone adapts to the changes of mechanical stimulus by bone remodeling activities. Bone remodeling results in the variation of bone density. This study presents the results of numerical simulations of biomechanics and mechanically adaptive bone remodeling in the human alveolar bone. Finite element models were built based on the micro X-ray computed tomography (micro-CT) images or clinical cone-beam computed tomography (CBCT) images. Strain in the alveolar bone under tooth loading or implant loading was calculated. Bone density distribution as a response to the mechanical stimulus was also computed. The results were in good agreement with experimentally measured strain using mechanical testing coupled with micro-CT and with the bone density distribution measured using clinical CBCT images. The models were used to predict the strain field with different implant positions. A number of numerical algorithms have been developed to model the adaptive bone remodeling under mechanical loads for orthopedic and dental applications. The parametric study examines the effects of several model parameters on the computed apparent bone density in mandible under normal chewing and biting forces. The density change rate was based on the strain energy density per unit mass. The algorithms used in this study containing an equilibrium zone (lazy zone) and saturated values of density change rate provided certain stability to result in convergence without discontinuous checkerboard patterns. The parametric study shows that when different boundary conditions were applied, the bone density distributions at convergence were very different, except in the vicinity of the applied loads. Compared with the effects of boundary conditions, the models are less sensitive to the choice of initial density values. Several models starting from different initial density values resulted in similar but not exactly the same bone density distribution at convergence. The results also show that, a higher reference value of mechanical stimulus resulted in lower average bone density at convergence. The width of equilibrium zone did not substantially affect the average density at convergence. However, with increasing width, the areas with the highest and the lowest bone density areas were all reduced. Moreover, the results of mechanically adaptive bone remodeling algorithms were compared with the information extracted from clinical images. Cone-beam computed tomography (CBCT) images of multiple patients were collected and processed to obtain the standard outline of mandible and average bone density distribution on the sagittal cross-sectional at the center of lateral incisors. Finite element models were built to compute the strain and stress in mandible under normal chewing and biting forces. Bone remodeling algorithm was carried out using strain energy density per unit bone mass as the mechanical stimulus to compute the bone density distribution at equilibrium. The computed bone density distribution exhibited close agreement with that obtained from CBCT image analysis with a coefficient of correlation of 0.87. The bite forces applied on teeth were transmitted through the tooth roots to the bone surrounding them, thus stimulated high trabecular bone density (1.6 g/cm3) near the tooth roots. The bending and torsion moments on the sagittal section of mandible resulted in lower bone density near the center (0.5 g/cm3) than those towards the edge of the section. The results add new knowledge of anatomy and biomechanics of mandibles and provide a new method to compare the results of numerical simulations of mechanically adaptive bone remodeling to in vivo data. Also, 3D finite element models were built based on micro-CT images and the results were compared with those obtained from mechanical testing coupled with micro-CT. Bone-implant mechanics is one of the factors that contribute to implant stability and success. In this work, voxel-based finite element models were built based on the micro-CT images of human cadaveric mandible specimens before and after implant placement. The elastic moduli of bone elements were assigned based on the intensity values in the micro-CT images of bone-tooth specimens before implant placement to avoid the beam hardening artifacts and to increase the connectivity and accuracy of the models. The implant positions in the models were determined by the micro-CT images of bone-implant specimens after implant placement. The computed results show that high strain appeared at the bone-implant contact locations and manifested into the supporting bone, including the buccal and lingual bone plates, which were not in direct contact with the implants. The strain concentration in the buccal bone plates was more substantial than that in the lingual bone plate, because the buccal bone plates were thinner than the lingual bone plates. The average values of maximum principal strain in the buccal and lingual regions of interest (ROI) were in good agreement with those experimentally measured using mechanical testing coupled with micro-CT and digital volume correlation. The implant positions were then virtually changed in the models by translating the implant towards the buccal or the lingual direction. The computed strain in the buccal bone decreased when the implant was virtually placed in the models away from the buccal bone plate. The strain in lingual bone also deceased when the implant was virtually moved in the model from the center of the alveolar socket towards the lingual or buccal plate. The results indicate that the distance of implant to the buccal bone plate can affect the mechanical stimuli in bone, especially in the buccal bone plate, which may subsequently affect the bone remodeling process and buccal bone resorption.
Author : Markel Diu00e9guez
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)
Download or read book Biomechanical Factors at Bone-implant Interface- an Animal Model Pilot Study written by Markel Diu00e9guez and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: BackgroundImplant-supported rehabilitations have become popular in last years because their high survival and success rates. Also, loading protocols have been shortened due to the development of the implant surfaces.During the provisionalitation of the implants the use of restoration with a high elastic material has been recommended to decrease the load transfer to the surrounding bone, because a load excess over the bone elastic limit could cause the implant loss due to overload. On the other hand, other in vitro studies recommended the use of higher Young u0301s modulus materials because they absorb the most part of the energy transferring less stress to the bone-implant interface.Also, splinting the implants designing splinted prosthetic structures guarantees that the maximum stress transferred to any of the implants will be lower than the load applied.This load control of implant-supported restorations is important because an excess of the stress transferred to the bone-implant interface could induce a micro motion >150u03bcm and the lost of the osseointegration.Hypothesis-Elastic materials in implant-supported restorations transfer less tension to the bone-implant interface.-Implant-supported splinted restorations transfer less tension to the bone-implant interface.-The lack of apex cortical causes more stress transmission to the bone-implant interface and higher micromotion of the implant.Materials and MethodsSix 3.5x8 Vega Klockner implants were inserted in both tibia of a New Zealand rabbit and RFA analysis was performed at this time by Penguin RFA device . An impression was carried out splinting the 3 implants with the transfer abutments to elaborate 2 identical single restorations, one of monolithic zirconia and another one of PMMA and 8 implant-supported bridges, 4 of each material with the same design. After 6 weeks of osseointegration, the animal was sacrificed and a new RFA analysis was carried out. Then, one strain gauge was stuck on the u201cbuccalu201d bone crest around each implant. Later, cement-screwed restorations were screwed at 30N to the implants and after this, a static and dynamic load of 100N was applied over the central fossa in the single restoration cases and over 3 different points when the bridges where screwed (firstly over the central fossa of one of the premolars, then over the other one and finally over the connector). Once the test was completed, all strain data were recorded. Finally, the apical cortical bone was removed and the load test was repeated in the same way.ResultsISQ mean value using multipage abutment was 62,8 (SD 10,35) in the moment of the surgery and 6 weeks after was 84,67 (SD 13,26) in the implants with the apical cortical bone (Group A) and 74.5 (SD 9,23) in the bone without apical cortical bone (Group B). Micro-strain mean value in single crowns was 103,08 u03bcstrains (SD 61,96) in group A and 471,94 u03bcstrains (SD 202,74) in group B. Micro-strain mean value in single crowns was 103,08 u03bcstrains (SD 61,96) in group A and 471,93 u03bcstrains (SD 202,74) in group B. In group A splinted crowns microstrain mean value was 57,03 u03bcstrains and in group B 202,1 u03bcstrains.Conclusions and Clinical Implications-When there is a lack of apical cortical bone ISQ values decrease. -Bone microstrains are higher when single crowns are placed and when there is an absence the apical cortical bone. -Bone microstrains are lower when the crowns are splinted and when there is a lack of the apical cortical this effect is more evident.-There is a tendency that the higher ISQ values the lower microstrain occurs at crestal level in all the cases. -When a dynamic load is applied bone microstrains are higher. -In most cases, monolithic zirconia causes higher bone microstrain.
Author : David B. Burr
Publisher : Academic Press
ISBN 13 : 0123914590
Total Pages : 390 pages
Book Rating : 4.1/5 (239 download)
Download or read book Basic and Applied Bone Biology written by David B. Burr and published by Academic Press. This book was released on 2013-06-11 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of skeletal biology from the molecular level to the organ level, including cellular control, interaction and response; adaptive responses to various external stimuli; the interaction of the skeletal system with other metabolic processes in the body; and the effect of various disease processes on the skeleton. The book also includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically modified animal models. - Presents an in-depth overview of skeletal biology from the molecular to the organ level - Offers "refresher" level content for clinicians or researchers outside their areas of expertise - Boasts editors and many chapter authors from Indiana and Purdue Universities, two of the broadest and deepest programs in skeletal biology in the US; other chapter authors include clinician scientists from pharmaceutical companies that apply the basics of bone biology
Author : Martin Groß
Publisher : GRIN Verlag
ISBN 13 : 3640139933
Total Pages : 111 pages
Book Rating : 4.6/5 (41 download)
Download or read book Finite Element Analysis of Bone Remodeling. Implementation of a Remodeling Algorithm in MATLAB and ANSYS written by Martin Groß and published by GRIN Verlag. This book was released on 2008-08-18 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master's Thesis from the year 2006 in the subject Medicine - Biomedical Engineering, grade: 1.0, Technical University of Munich (LS Statik), course: Master of Science of Computational Mechanics, language: English, abstract: The process of adaptive bone remodeling can be described mathematically and simulated in a computer model, integrated with the finite element method. The main focus of this thesis is the implementation of a bone remodeling algorithm in MATLAB and ANSYS on the basis of FEM. The strain energy density is used as mechanical stimulus. The cortical and trabecular bone are described as continuous materials with variable density. This thesis can be divided into four main parts. The first part is due to the material properties of cortical and trabecular bone. The second part is about the remodeling theory and gives an historical review of the developed numerical approaches up to now. The implementation of the remodeling algorithm in ANSYS and MATLAB as well as its validation is topic of part three. In last main part, the algorithm is applied to a 2D FE-model of a human proximal femur.
Author : Louis V. Avioli
Publisher : Academic Press
ISBN 13 : 0080536271
Total Pages : 843 pages
Book Rating : 4.0/5 (85 download)
Download or read book Metabolic Bone Disease and Clinically Related Disorders written by Louis V. Avioli and published by Academic Press. This book was released on 1997-10-08 with total page 843 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Bone Disease, Third Edition is the new, expanded edition of the classic text, featuring the latest advancements and research information in this fast-moving field. The Third Edition includes the most up-to-date information on molecular mechanisms, basic biology, pathophysiology, and diagnosis and management strategies of metabolic bone disease. - Edited by "fathers of the field" - An expanded version of a classic AP text - Complete coverage of a fast-growing field
