Author : Natalie Janelle German
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (914 download)
Book Synopsis Investigating and Exploiting Metabolic Vulnerabilities in Cancer by : Natalie Janelle German
Download or read book Investigating and Exploiting Metabolic Vulnerabilities in Cancer written by Natalie Janelle German and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Fuel metabolism in healthy cells is not sufficient to sustain the biosynthetic and energetic demands of cancer. For a normal cell to transform to a rapidly dividing tumor cell, metabolism must be dramatically altered in a process called metabolic reprogramming, characterized by increased nutrient uptake and re-purposing. As we move toward a future of personalized medicine, there is new opportunity in targeting the metabolic requirements specific to an individual's tumor. To this end, it is critical to understand molecular drivers that cancer cells hijack to modify metabolism.