Intractable Seizures

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461513359
Total Pages : 252 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Intractable Seizures by : W. McIntyre Burnham

Download or read book Intractable Seizures written by W. McIntyre Burnham and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: About 20% of people with epilepsy have seizures which are resistant to anticonvulsant medications. These drug-resistant seizures are called `intractable', and the patients who have them - about 1 in 500 of the general population - present a major challenge to neurologists and epilepsy associations. The present volume describes the symptomatology of the major `intractable' syndromes, the most appropriate drugs for each, and the possibilities for surgical control. Research related to the causes and effects of unchecked seizures is presented, and new directions in prevention and therapy are discussed.

Models of Seizures and Epilepsy

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Author :
Publisher : Academic Press
ISBN 13 : 012804067X
Total Pages : 1178 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Models of Seizures and Epilepsy by : Asla Pitkänen

Download or read book Models of Seizures and Epilepsy written by Asla Pitkänen and published by Academic Press. This book was released on 2017-06-14 with total page 1178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

Intractable Focal Epilepsy

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Author :
Publisher : Bailliere Tindall Limited
ISBN 13 : 9780702024283
Total Pages : 0 pages
Book Rating : 4.0/5 (242 download)

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Book Synopsis Intractable Focal Epilepsy by : John Oxbury

Download or read book Intractable Focal Epilepsy written by John Oxbury and published by Bailliere Tindall Limited. This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intractable Focal Epilepsyis a definitive multi author reference work covering the most difficult to treat epilepsies. The natural history, pathology and treatment, both medical and surgical, of the conditions underlying intractable seizures are fully described and illustrated. Including contributions from North America, Europe and the Pacific Rim, the emphasis throughout is on clinical diagnosis and treatment both medical and surgical, and their respective outcomes. The text is enhanced by over 250 illustrations, and the clear modern design enables the reader to assimilate information quickly. In addition to clinical treatment, there is a section on the costs of persistent intractable focal epilepsy and the costs of surgical treatment. Drs Oxbury, Polkey and Duchowny have produced a book that will appeal to epileptologists, paediatric neurologists, and neurosurgeons. The books clinical strengths will make it an invaluable working tool. Definitive resource on difficult to treat epilepsies Covers manifestation, consequences and treatment Major section on surgical treatment of focal epilepsy Complete coverage of paediatric diagnosis and treatment Special "Case Reports" give practical case histories to illustrate clinical points International line up of contributors

Intractable Epilepsy

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 298 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Intractable Epilepsy by : Dieter Schmidt (M.D.)

Download or read book Intractable Epilepsy written by Dieter Schmidt (M.D.) and published by Lippincott Williams & Wilkins. This book was released on 1986 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diagnosis and Surgical Treatment of Epilepsy

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Author :
Publisher : MDPI
ISBN 13 : 3038974498
Total Pages : 136 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Diagnosis and Surgical Treatment of Epilepsy by : Warren W. Boling

Download or read book Diagnosis and Surgical Treatment of Epilepsy written by Warren W. Boling and published by MDPI. This book was released on 2019-01-09 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Diagnosis and Surgical Treatment of Epilepsy" that was published in Brain Sciences

Pharmacoresistance in Epilepsy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461464641
Total Pages : 333 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Pharmacoresistance in Epilepsy by : Luisa Rocha

Download or read book Pharmacoresistance in Epilepsy written by Luisa Rocha and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although more than 10 new antiepileptic drugs have been developed in the past decade, epilepsy remains resistant to drug therapy in about one third of patients, many of whom struggle with the disease their entire lives. Managing these patients is a challenge and requires a structured multidisciplinary approach. The book includes chapters on all issues related to pharmacoresistance in epilepsy and describes recent developments in the pathogenesis and treatment of this disorder. It addresses abnormalities in inhibitory mechanisms, epilepsy-related changes to the immune system, development of pharmacoresistance caused by chronic exposure to antiepileptic drugs, and novel therapeutic strategies for preventing or slowing down the progression of the disease. Clinicians and basic scientists alike will find up-to-date information on the development of pharmacoesistance, as well as reviews of mechanisms associated with epilepsy that may help them consider novel strategies for preventing the development of pharmacoresistance in the first place. The book also features information on new therapeutic strategies for control of epilepsy, such as transcutaneous electrical stimulation and virtual screening of new antiepileptic drugs. Pharmacoresistance in Epilepsy: From Genes and Molecules to Promising Therapies is useful to anyone working in the field, whether they’re studying epilepsy in the lab or treating it in a doctor’s office.”

The Comorbidities of Epilepsy

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Author :
Publisher : Academic Press
ISBN 13 : 0128148780
Total Pages : 413 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Comorbidities of Epilepsy by : Marco Mula

Download or read book The Comorbidities of Epilepsy written by Marco Mula and published by Academic Press. This book was released on 2019-04-20 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers. Provides a comprehensive overview of somatic, neurological and behavioral co-morbidities of epilepsy Discusses up-to-date management of comorbidities of epilepsy Written by a group of international experts in the field

Intractable Epilepsy

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Author :
Publisher : Wrightson Biomedical Pub Limited
ISBN 13 : 9781871816280
Total Pages : 267 pages
Book Rating : 4.8/5 (162 download)

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Book Synopsis Intractable Epilepsy by : Svein I. Johannessen

Download or read book Intractable Epilepsy written by Svein I. Johannessen and published by Wrightson Biomedical Pub Limited. This book was released on 1995 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: In most patients with epilepsy the prognosis for seizure control is very good. However, despite the introduction of new antiepileptic drugs and excellent monitoring methods, about 25% of patients develop chronic epilepsy which does not respond to treatment. Intractable epilepsy has a major impact on patients' quality of life and represents a considerable challenge for both the clinician attempting to effect seizure control and the researcher trying to understand why it develops and whether it can be prevented. This important new book defines intractable epilepsy, examines its consequences, risks and costs, discusses diagnosis and medical management, including novel drug therapies, neurosurgery and vagal stimulation, and sheds new light on its evolution and aetiology. Intractable Epilepsy is intended for neurologists, paediatricians, neurosurgeons, psychiatrists and other professionals involved in the management, investigation or study of intractable seizures.

Operative Techniques in Epilepsy Surgery

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Author :
Publisher : Thieme
ISBN 13 : 1626238197
Total Pages : 598 pages
Book Rating : 4.6/5 (262 download)

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Book Synopsis Operative Techniques in Epilepsy Surgery by : Gordon H. Baltuch

Download or read book Operative Techniques in Epilepsy Surgery written by Gordon H. Baltuch and published by Thieme. This book was released on 2019-11-07 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: An indispensable, single-volume resource on state-of-the-art epilepsy procedures from renowned international experts! Epilepsy is a common neurological disorder affecting an estimated 1% of the population, about 20 to 30% of which experience seizures inadequately controlled by medical therapy alone. Advances in anatomic and functional imaging modalities, stereotaxy, and the integration of neuronavigation during surgery have led to cutting-edge treatment options for patients with medically refractory epilepsy. Operative Techniques in Epilepsy Surgery, Second Edition by Gordon Baltuch, Arthur Cukiert, and an impressive international group of contributors has been updated and expanded, reflecting the newest treatments for pediatric and adult epilepsy. Seven sections with 30 chapters encompass surgical planning, invasive EEG studies, cortical resection, intraoperative mapping, disconnection, neuromodulation, and further topics. Twelve cortical resection chapters cover surgical approaches such as amygdalohippocampectomy; hippocampal transection; frontal lobe, central region, and posterior quadrant resections; and microsurgery versus endoscopy for hypothalamic hamartomas. Disconnection procedures discussed in section five include corpus callosotomy, hemispherectomy, and endoscopic-assisted approaches. Well-established procedures such as vagus nerve and deep brain stimulation are covered in the neuromodulation section, while the last section discusses radiosurgery for medically intractable cases. Key Highlights Chapters new to this edition include endoscopic callosotomy, laser-induced thermal therapy (LITT), and focused ultrasound High-quality illustrations, superb operative and cadaver photographs, radiologic images, and tables enhance understanding of impacted anatomy and specific techniques The addition of videos provides insightful step-by-step procedural guidance This is an essential reference for fellows and residents interested in epilepsy and functional neurosurgery, and an ideal overview for neurosurgeons, neurologists, and neuroradiologists in early career stages who wish to pursue this subspecialty.

Magnetic Resonance in Epilepsy

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Author :
Publisher : Academic Press
ISBN 13 : 0080535712
Total Pages : 461 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Magnetic Resonance in Epilepsy by : Ruben Kuzniecky

Download or read book Magnetic Resonance in Epilepsy written by Ruben Kuzniecky and published by Academic Press. This book was released on 2005-01-19 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Remarkable advances in imaging have increased the importance of MRI for diagnostic, treatment and management of epilepsy. Neuroimaging of patients with epilepsy no longer simply deals with the technology and interpretation of images but also with issues of brain metabolism, energetics, cognition and brain dysfunction. The first edition of Magnetic Resonance in Epilepsy came into clinical practice in 1995 with a revolutionary idea; that is, MR is as important as EEG in the clinical management of patients with epilepsy. The second edition of Magnetic Resonance in Epilepsy, the only comprehensive text in the field of epilepsy neuroimaging, reviews fundamental concepts and new advances in MR technology, computerized analysis, MR spectroscopy, DWI and other neuroimaging techniques such as PET, SPECT and MEG application to the study of patients with epileptic disorders. *Provides a crucial update of recent advances in imaging techniques*Timely publication as subject of neuroimaging is a very "hot" area in both clinical epilepsy and basic neuroscience research*Editors are well-respected in this field

Epilepsy

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119431824
Total Pages : 550 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Epilepsy by : Gregory D. Cascino

Download or read book Epilepsy written by Gregory D. Cascino and published by John Wiley & Sons. This book was released on 2021-08-02 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to provide a comprehensive but accessible introduction to epilepsy and seizure disorders, Epilepsy, 2nd edition provides state-of-the-art information in a concise format useful to a wide audience, from neurology residents to epilepsy fellows and practitioners. This illustrated guide to the assessment, diagnosis, and treatment of epilepsy is a valuable resource enabling clinicians to stay on top of the latest recommendations for best practice.

Subthalamic and Thalamic Stereotactic Recordings and Stimulations in Patients with Intractable Epilepsy

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Author :
Publisher : John Libbey Eurotext
ISBN 13 : 2742009663
Total Pages : 206 pages
Book Rating : 4.7/5 (42 download)

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Book Synopsis Subthalamic and Thalamic Stereotactic Recordings and Stimulations in Patients with Intractable Epilepsy by : Heinz Gregor Wieser

Download or read book Subthalamic and Thalamic Stereotactic Recordings and Stimulations in Patients with Intractable Epilepsy written by Heinz Gregor Wieser and published by John Libbey Eurotext. This book was released on 2008-02-01 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Various subcortical structures in the brain are thought to be important in genesis or propagation of seizures. Deep Brain Stimulation (DBS) of these structures aims to influence these key “pacemaker” areas in the brain and is gaining increasing interest as a possible new surgical modality for treatment of patients with intractable epilepsy. Based on this background, this volume brings together the experience of the Zurich Epilepsy Surgery Center with stereotactic recordings and stimulations of various subcortical nuclei, with special reference to the Forel H fields, the thalamic nuclei and the periaqueductal gray matter. This volume also addresses the important issues of DC recording/polarisation and of biochemical measurement of excitatory and inhibitory transmitters released in the primary epileptogenic area during epileptic discharges. This book is destined to improve understanding of the involvement of subcortical structures in seizure genesis or propagation in a time when exhaustive invasive presurgical evaluation is diminishing because of the today’s availability of modern non-invasive imaging technique.

Epilepsy Surgery and Intrinsic Brain Tumor Surgery

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Author :
Publisher : Springer
ISBN 13 : 3319959182
Total Pages : 301 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Epilepsy Surgery and Intrinsic Brain Tumor Surgery by : Konstantinos Fountas

Download or read book Epilepsy Surgery and Intrinsic Brain Tumor Surgery written by Konstantinos Fountas and published by Springer. This book was released on 2018-10-03 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and practical guide for the safe and efficient management of patients with intrinsic brain tumors and medically intractable epilepsy. It presents in an easily understandable way the preoperative evaluation of these patients, starting from the clinical interpretation of conventional anatomical MR imaging and analyses the clinical significance of newer MR based imaging techniques such as diffusion and perfusion imaging. It demonstrates with clarity the role of MR spectroscopy and fractional anisotropy and diffusion tensor imaging in the preoperative assessment of these patients and how this data can be incorporated into the surgical planning. This book is aimed at neurosurgeons, neuroradiologists, neurologists, and epileptologists, and may also be of interest to neuropsychologists, neurophysiologists, radiation oncologists, and medical physicists.

Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

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Author :
Publisher : Elsevier
ISBN 13 : 0124105491
Total Pages : 1465 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease by : Roger N. Rosenberg

Download or read book Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease written by Roger N. Rosenberg and published by Elsevier. This book was released on 2014-10-28 with total page 1465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations

Epilepsy and Brain Tumors

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Author :
Publisher : Elsevier
ISBN 13 : 0124171265
Total Pages : 292 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Epilepsy and Brain Tumors by : Herbert B. Newton

Download or read book Epilepsy and Brain Tumors written by Herbert B. Newton and published by Elsevier. This book was released on 2015-03-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously – a brain tumor and a secondary form of epilepsy. Although there has been remarkable progress in BTRE research in recent years, it remains an on-going challenge for clinicians and continues to stimulate much debate in the scientific community. This volume is the first to be completely dedicated to BTRE, and in doing so it explores issues faced by the health care team as well as some of the novel and promising directions that future research may take. Epilepsy and Brain Tumors is not only a complete reference on BTRE but also a practical guide based on clinical experiences, with a comprehensive collection of presentations from international experts who share some of the latest discoveries and their approaches to tackling a wide range of difficult and complex issues. Includes coverage of epidemiology, pathology and treatment of both primary and metastatic brain tumors Offers additional insight into supportive care, incidence in children, focal epileptogenesis, clinical evaluation, antiepileptic drugs, surgical treatment, cognitive rehabilitation, and more Chapters authored and edited by leaders in the field around the globe – the broadest, most expert coverage available

Medication-Resistant Epilepsy

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1108916236
Total Pages : 287 pages
Book Rating : 4.1/5 (89 download)

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Book Synopsis Medication-Resistant Epilepsy by : John M. Stern

Download or read book Medication-Resistant Epilepsy written by John M. Stern and published by Cambridge University Press. This book was released on 2020-09-10 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fifty million people worldwide have epilepsy and yet up to 35% of patients experience seizures that are resistant to anti-epileptic drugs. Patients with medication-resistant epilepsy have increased risks of premature death, psychosocial dysfunction and a reduced quality of life. This key resource delivers guidance for all clinicians involved in caring for patients with medication-resistant epilepsy in order to reduce these risks. Covering the epidemiology, biology, causes and potential treatments for medication-resistant epilepsy, this definitive and focused text reviews the clinical care needs of patients. Guidance is practical and includes treatment for specialized groups including pediatric patients and those with psychiatric comorbidities. Several promising non-pharmacologic interventions available for patients, such as surgery, neuromodulation diet therapy and botanical treatment are explored in detail. Leading international figures from a range of disciplines bring their expertise together holistically in this essential manual.

Epilepsy and the Corpus Callosum

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 146132419X
Total Pages : 532 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Epilepsy and the Corpus Callosum by : Alexander G. Reeves

Download or read book Epilepsy and the Corpus Callosum written by Alexander G. Reeves and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: InJuly 1982 the first Dartmouth workshop on the corpus callosum took place. A nucleus of basic and clinical scientists was convened to give progress reports of their work on the corpus callosum. This text was subsequently compiled by the various participants from these reports modified by a stimulating cross fertilization of ideas and subsequent studies. Four and one-half decades have intervened since Van Wagenen first sectioned the corpus callosum for epilepsy (Van Wagenen and Herren, 1940) and Erickson (1940) demonstrated that the corpus callosum is the major route for generalization of experimentally induced focal cortical epilepsy. During the succeeding 45 years a handful of clinicians has pursued these leads to confirm the therapeutic value of callosotomy for some types of medically intractable generalized epilepsy. Parallel experimental studies with a number of epilepsy models have indicated that the corpus callosum is indeed the major route for seizure generalization, that the brainstem is a secondary and more resistant pathway for seizure generalization, and that most if not all epileptic seizures originate from the cerbral cortex. The unexpected clinical finding that even partial (focal) seizure incidence is modified by callosotomy now has been demonstrated in the laboratory. The various contributors to the clinical and experimental epilepsy sections of this volume have been seminal in these elucidations, as will be evident from their chapters. The section on the development, anatomy, and physiology of the corpus callosum demonstrates that these basic areas of study have not been neglected.