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Author : Dale A. Stringfellow
Publisher :
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.3/5 (91 download)
Download or read book Interferon and Interferon Inducers, Clinical Applications written by Dale A. Stringfellow and published by . This book was released on 1980 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Dale A. Stringfellow
Publisher : Marcel Dekker
ISBN 13 :
Total Pages : 304 pages
Book Rating : 4.3/5 (91 download)
Download or read book Clinical Application of Interferons and Their Inducers written by Dale A. Stringfellow and published by Marcel Dekker. This book was released on 1986 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Dale A. Stringfellow
Publisher :
ISBN 13 : 9780835761628
Total Pages : 343 pages
Book Rating : 4.7/5 (616 download)
Download or read book Interferon and Interferon Inducers written by Dale A. Stringfellow and published by . This book was released on 1980 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : W. Stinebring
Publisher : Springer Science & Business Media
ISBN 13 : 1461590809
Total Pages : 220 pages
Book Rating : 4.4/5 (615 download)
Download or read book Human Interferon written by W. Stinebring and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Roumen G. Tsanev
Publisher : CRC Press
ISBN 13 : 1420040731
Total Pages : 321 pages
Book Rating : 4.4/5 (2 download)
Download or read book Immune Interferon written by Roumen G. Tsanev and published by CRC Press. This book was released on 2001-11-28 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now for the first time, one comprehensive book summarizes and analyzes the numerous scientific papers and reviews covering selected aspects of the structure, biological activities, and clinical effects of immune interferon, also known as interferon-gamma(IFN-gamma). Immune Interferon: Properties and Clinical Applications is essential reading for an
Author : Karol Sikora
Publisher : Springer Science & Business Media
ISBN 13 : 1468411705
Total Pages : 212 pages
Book Rating : 4.4/5 (684 download)
Download or read book Interferon and Cancer written by Karol Sikora and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interferon was first discovered in 1957. Over the last five years it has become almost a household word. Many believe it to be a drug with already proven efficacy against cancer and viral infection. The media has distorted any cool scientific view of the data available. We have learned much about the complexity of the interferon system. We know some of the switches involved in interferon gene expression and its secretion by virally and immune stimulated cells. We also know that it binds to a cell surface receptor, mediating its complex effects on target cells by a series of second messengers. The advent of the new techniques of modern molecular biology, such as monoclonal antibodies and gene cloning, has had tremendous impact on the rate of acquisition of knowledge. Such techniques have provided us with almost unlimited quantities of highly purified interferon for clinical trial in patients with a spectrum of infectious and malignant diseases. The information we have gathered raises many more questions. Why should there be several families of interferon genes? What is their true physiolo gical role? How are they interrelated functionally? Interferon is clearly a cellular hormone providing a means of communication between cells. ~fhether it has clinical value in the management of patients with diseased cells remains to be seen. This book sum marises our current knowledge of interferons as possible an- cancer agents. It is clear interferon is no penicillin for cancer.
Author : P.E. Came
Publisher : Springer Science & Business Media
ISBN 13 : 3642691781
Total Pages : 585 pages
Book Rating : 4.6/5 (426 download)
Download or read book Interferons and Their Applications written by P.E. Came and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, the basic mood of researchers and clinical investigators, both at the center and on the periphery of interferon studies, is optimistic regarding the future of interferons as therapeutic substances. Many also feel these polypeptides will prove invaluable probes in unraveling certain fundamental biochemical processes which control the life cycle and developmental pattern of many human cells. In contrast, only a year or two ago, this optimism had given way to an attitude almost of disenchantment as public and scientific expectations were raised steeply, then rapidly waned, as it turns out, prematurely. Both the mUltiple actions of interferons (a virtual cascade of biochemical reactions may be induced, as documented herein) and the high visibility of interferon research provided by the millions of dollars invested both by national health agencies and by multinational pharmaceutical companies, contributed to an upsweep in public attention to drug development probably unprecedented in this century. Virtually every oncologist, it would seem, was plagued by requests for the experimental agent, although they already had therapies of more proven value. As recently as 1980, even though interferon had achieved success against certain cancers and certain viral diseases, the variability in clinical results was seemingly ever present and little evidence emerged to suggest interferons could cure advanced diseases. Why then the resurgence of an optimistic mood? There are almost always many elements which contribute to happiness, and this is certainly true of the broad frontier of interferon and its place in biochemical research and treatment.
Author : Robert Friedman
Publisher : Elsevier
ISBN 13 : 0323160859
Total Pages : 164 pages
Book Rating : 4.3/5 (231 download)
Download or read book Interferons A Primer written by Robert Friedman and published by Elsevier. This book was released on 2012-12-02 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interferons: A Primer covers general information on interferon, including analysis, purification, production, properties, mechanism of action, and clinical uses. Organized into 10 chapters, the book starts with a short history of interferon’s discovery by Isaacs and Lindenmann, followed by topics on assays for interferon, such as factors affecting interferon assays and rapid biological assay. Chapters 3 to 6 discuss the purification, properties, production, antiviral action, and other functions of interferon. Chapters 7 and 8 examine the recovery from viral infection and clinical uses of interferon, with emphasis on treatment of human cancer. The concluding chapters focus on the application of interferon studies on two revolutionizing fields of biology, namely, the cloning of animal genes in microorganisms and the production of monoclonal antibodies. This book is intended for students, scientists, physicians, or educated laypersons who wish to know something about interferons, but do not plan carrying out research in this area.
Author : Carlo Aul
Publisher : Springer Science & Business Media
ISBN 13 : 3642604110
Total Pages : 302 pages
Book Rating : 4.6/5 (426 download)
Download or read book Interferons written by Carlo Aul and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interferons were among the first cytokines to be studied clinically in recombinant form in the 1980s, beginning a new era of pharmacotherapy in internal medicine. Interferons were soon employed in the treatment of tumors and it was shown that those hematopoietic neoplasias which had been difficult to treat with chemotherapy responded well to interferon treatment. In the present volume, renowned international authors update the importance of interferons in various fields of internal medicine, dermatology, and urology. The book also contains a general introduction into the classification, structure, and mode of action of interferons. Further chapters discuss the range of side effects of these substances and point out possible focuses of further clinical interferon research.
Author : David Arthur John Tyrrell
Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.:/5 (44 download)
Download or read book Interferon and Its Clinical Potential written by David Arthur John Tyrrell and published by . This book was released on 1976 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Norman B. Finter
Publisher :
ISBN 13 :
Total Pages : 626 pages
Book Rating : 4.F/5 ( download)
Download or read book Interferons and Interferon Inducers written by Norman B. Finter and published by . This book was released on 1973 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Karol Sikora
Publisher : Springer
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.:/5 (45 download)
Download or read book Interferon and Cancer written by Karol Sikora and published by Springer. This book was released on 1983-06 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interferon was first discovered in 1957. Over the last five years it has become almost a household word. Many believe it to be a drug with already proven efficacy against cancer and viral infection. The media has distorted any cool scientific view of the data available. We have learned much about the complexity of the interferon system. We know some of the switches involved in interferon gene expression and its secretion by virally and immune stimulated cells. We also know that it binds to a cell surface receptor, mediating its complex effects on target cells by a series of second messengers. The advent of the new techniques of modern molecular biology, such as monoclonal antibodies and gene cloning, has had tremendous impact on the rate of acquisition of knowledge. Such techniques have provided us with almost unlimited quantities of highly purified interferon for clinical trial in patients with a spectrum of infectious and malignant diseases. The information we have gathered raises many more questions. Why should there be several families of interferon genes? What is their true physiolo gical role? How are they interrelated functionally? Interferon is clearly a cellular hormone providing a means of communication between cells. ~fhether it has clinical value in the management of patients with diseased cells remains to be seen. This book sum marises our current knowledge of interferons as possible an- cancer agents. It is clear interferon is no penicillin for cancer.
Author : William E. Stewart
Publisher :
ISBN 13 :
Total Pages : 236 pages
Book Rating : 4.:/5 (44 download)
Download or read book Interferons and Their Actions written by William E. Stewart and published by . This book was released on 1977 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kathryn C. Zoon
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.:/5 (44 download)
Download or read book Interferon--research, Clinical Application, and Regulatory Consideration written by Kathryn C. Zoon and published by Elsevier Publishing Company. This book was released on 1984 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : John Wiley & Sons
ISBN 13 : 111817979X
Total Pages : 744 pages
Book Rating : 4.1/5 (181 download)
Download or read book Biotechnology and Biopharmaceuticals written by and published by John Wiley & Sons. This book was released on 2013-12-16 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs, Second Edition addresses the pivotal issues relating to translational science, including preclinical and clinical drug development, regulatory science, pharmaco-economics and cost-effectiveness considerations. The new edition also provides an update on new proteins and genetic medicines, the translational and integrated sciences that continue to fuel the innovations in medicine, as well as the new areas of therapeutic development including cancer vaccines, stem cell therapeutics, and cell-based therapies.
Author : Samuel Baron
Publisher :
ISBN 13 :
Total Pages : 644 pages
Book Rating : 4.3/5 (91 download)
Download or read book Interferon written by Samuel Baron and published by . This book was released on 1992 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Joe H. Thomas
Publisher : Nova Science Publishers
ISBN 13 : 9781620812983
Total Pages : 0 pages
Book Rating : 4.8/5 (129 download)
Download or read book Interferons written by Joe H. Thomas and published by Nova Science Publishers. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interferons are cytokines that are very important in regulating both innate and adaptive immune response. Of the two different types of interferons, Type I interferons are potent mediators of the innate immune response against viruses and cancer. Type II interferons, mainly IFN-y enhances T cell polarisation in the lymph nodes that result in their expansion. This book discusses the characterisation, mechanisms of action and clinical applications of interferons. Topics include interferon-gamma, oligodendrocyte injury and inflammatory demyelination; the role of IFN-y in oesophageal squamous cell carcinoma; interferons in multiple sclerosis; the effect of interferons on NK cell activity in HIV infection and tumour cell development; and understanding the mechanisms of interaction between serine proteases, serine protease receptors and interferons.
