Integrated Omics Approaches To Infectious Diseases

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Integrated Omics Approaches to Infectious Diseases

Author : Saif Hameed
Publisher :
ISBN 13 : 9789811606922
Total Pages : 0 pages
Book Rating : 4.6/5 (69 download)

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Book Synopsis Integrated Omics Approaches to Infectious Diseases by : Saif Hameed

Download or read book Integrated Omics Approaches to Infectious Diseases written by Saif Hameed and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology.

Integrated Omics Approaches to Infectious Diseases

Author : Saif Hameed
Publisher : Springer Nature
ISBN 13 : 9811606919
Total Pages : 538 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Integrated Omics Approaches to Infectious Diseases by : Saif Hameed

Download or read book Integrated Omics Approaches to Infectious Diseases written by Saif Hameed and published by Springer Nature. This book was released on 2021-07-18 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology.

Evolution of Translational Omics

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309224187
Total Pages : 354 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Evolution of Translational Omics by : Institute of Medicine

Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Computational Epigenetics and Diseases

Author :
Publisher : Academic Press
ISBN 13 : 0128145145
Total Pages : 452 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Computational Epigenetics and Diseases by :

Download or read book Computational Epigenetics and Diseases written by and published by Academic Press. This book was released on 2019-02-06 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, in the context of human diseases. This book discusses bioinformatics methods for epigenetic analysis specifically applied to human conditions such as aging, atherosclerosis, diabetes mellitus, schizophrenia, bipolar disorder, Alzheimer disease, Parkinson disease, liver and autoimmune disorders, and reproductive and respiratory diseases. Additionally, different organ cancers, such as breast, lung, and colon, are discussed. This book is a valuable source for graduate students and researchers in genetics and bioinformatics, and several biomedical field members interested in applying computational epigenetics in their research. - Provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases - Summarizes the major computational tools, databases, and strategies for computational epigenetics analysis, such as DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA - Covers the major milestones and future directions of computational epigenetics in various kinds of human diseases such as aging, atherosclerosis, diabetes, heart disease, neurological disorders, cancers, blood disorders, liver diseases, reproductive diseases, respiratory diseases, autoimmune diseases, human imprinting disorders, and infectious diseases

Omics Approaches in Veterinary Parasitology

Author : Muhammad Sohail Sajid
Publisher : CRC Press
ISBN 13 : 104015509X
Total Pages : 206 pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis Omics Approaches in Veterinary Parasitology by : Muhammad Sohail Sajid

Download or read book Omics Approaches in Veterinary Parasitology written by Muhammad Sohail Sajid and published by CRC Press. This book was released on 2024-11-28 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omics Approaches in Veterinary Parasitology: Diagnosis, Biomarkers, and Drug Development explores applications of omics approaches for diagnosis, biomarker discovery, and drug development against parasites of veterinary importance. It presents the fundamental principles of parasite biology and their complex physiological processes. The chapters review key aspects such as parasite life cycles, host-parasite interactions, and the molecular mechanisms that underlie parasitic diseases. The subsequent chapters delve into the principles and applications of genomics, transcriptomics, proteomics, and metabolomics in understanding parasites at a molecular level. The use of next-generation sequencing, PCR-based assays, and metagenomics in identifying and characterizing parasites for accurate and efficient diagnosis are also covered in detail. Toward the end, the book focuses on target identification, drug repurposing, and the optimization of drug efficacy while minimizing drug resistance using omics data. The book is useful for researchers, students, and professionals in the field of veterinary parasitology.

Multi-Omics Approaches to Study Signaling Pathways

Author : Jyoti Sharma
Publisher : Frontiers Media SA
ISBN 13 : 2889661253
Total Pages : 154 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Multi-Omics Approaches to Study Signaling Pathways by : Jyoti Sharma

Download or read book Multi-Omics Approaches to Study Signaling Pathways written by Jyoti Sharma and published by Frontiers Media SA. This book was released on 2020-11-18 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Molecular Epidemiology

Author : Paul A. Schulte
Publisher : Academic Press
ISBN 13 : 0323138578
Total Pages : 609 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Molecular Epidemiology by : Paul A. Schulte

Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Omics for Personalized Medicine

Author : Debmalya Barh
Publisher : Springer Science & Business Media
ISBN 13 : 8132211847
Total Pages : 825 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Omics for Personalized Medicine by : Debmalya Barh

Download or read book Omics for Personalized Medicine written by Debmalya Barh and published by Springer Science & Business Media. This book was released on 2013-10-14 with total page 825 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Omics for Personalized Medicine” will give to its prospective readers the insight of both the current developments and the future potential of personalized medicine. The book brings into light how the pharmacogenomics and omics technologies are bringing a revolution in transforming the medicine and the health care sector for the better. Students of biomedical research and medicine along with medical professionals will benefit tremendously from the book by gaining from the diverse fields of knowledge of new age personalized medicine presented in the highly detailed chapters of the book. The book chapters are divided into two sections for convenient reading with the first section covering the general aspects of pharmaocogenomic technology that includes latest research and development in omics technologies. The first section also highlights the role of omics in modern clinical trials and even discusses the ethical consideration in pharmocogenomics. The second section is focusing on the development of personalized medicine in several areas of human health. The topics covered range from metabolic and neurological disorders to non-communicable as well as infectious diseases, and even explores the role of pharmacogenomics in cell therapy and transplantation technology. Thirty-four chapters of the book cover several aspects of pharmacogenomics and personalized medicine and have taken into consideration the varied interest of the readers from different fields of biomedical research and medicine. Advent of pharmacogenomics is the future of modern medicine, which has resulted from culmination of decades of research and now is showing the way forward. The book is an honest endeavour of researchers from all over the world to disseminate the latest knowledge and knowhow in personalized medicine to the community health researchers in particular and the educated public in general.

Computational Systems Biology

Author : Andres Kriete
Publisher : Academic Press
ISBN 13 : 0124059384
Total Pages : 549 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Computational Systems Biology by : Andres Kriete

Download or read book Computational Systems Biology written by Andres Kriete and published by Academic Press. This book was released on 2013-11-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. - Logical information flow aids understanding of basic building blocks of life through disease phenotypes - Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns - Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation - Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.

Calcific Aortic Valve Disease

Author : Elena Aikawa
Publisher : BoD – Books on Demand
ISBN 13 : 9535111507
Total Pages : 544 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Calcific Aortic Valve Disease by : Elena Aikawa

Download or read book Calcific Aortic Valve Disease written by Elena Aikawa and published by BoD – Books on Demand. This book was released on 2013-06-12 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

Biological Insights of Multi-Omics Technologies in Human Diseases

Author : Aarif Ali
Publisher : Elsevier
ISBN 13 : 0443239703
Total Pages : 420 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Biological Insights of Multi-Omics Technologies in Human Diseases by : Aarif Ali

Download or read book Biological Insights of Multi-Omics Technologies in Human Diseases written by Aarif Ali and published by Elsevier. This book was released on 2024-05-23 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Biological Insights of Multi-Omics Technologies in Human Diseases ́ provides detailed information about the basics of multi-omic technologies including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharmaceutical, socio-ethical, and economic perspectives. The chapters are designed in a well-defined chronology such that readers will intuitively understand the central idea. This book is an ideal resource for health professionals, scientists and researchers, nutritionists, health practitioners, students, and all those who wish to broaden their knowledge in the allied field. • Explains the in-depth role of multi-omics on drug discovery/metabolism, diseases, and highlights progress in both the research and clinical areas of computation, as well as relevant implementation experience and challenges. • Describes the practice of multi-omic technologies in the treatment of several diseases.• Includes practical application and machine learning approaches of multi-omics.

Omics Technologies for Clinical Diagnosis and Gene Therapy: Medical Applications in Human Genetics

Author : Syeda Marriam Bakhtiar
Publisher : Bentham Science Publishers
ISBN 13 : 9815079522
Total Pages : 334 pages
Book Rating : 4.8/5 (15 download)

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Book Synopsis Omics Technologies for Clinical Diagnosis and Gene Therapy: Medical Applications in Human Genetics by : Syeda Marriam Bakhtiar

Download or read book Omics Technologies for Clinical Diagnosis and Gene Therapy: Medical Applications in Human Genetics written by Syeda Marriam Bakhtiar and published by Bentham Science Publishers. This book was released on 2022-10-03 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic disorders have been the focus of scientists for a long time. The emergence of next-generation sequencing techniques has ushered a new era in genetics and several developments have occurred in human genetics. The scientific perspective has also been widened with omics technologies that allow researchers to analyze genetic sequences and their expression products. An integrated approach is being used not only for diagnosis but also for disease management and therapeutic purposes. This book highlights emerging areas of omics technology and its application in the diagnosis and management of human genetic disorders. The book covers three areas of research and implementation: 1) Diagnosis (covering conventional strategies to next-generation platforms). This section focuses on the role of in silico analysis, databases and multi-omics of single-cell which will help in designing better management strategies. 2) Disease Management and therapeutic interventions. This section starts with genetic counselling and progresses to more specific techniques such as pharmacogenomics and personalized medicine, gene editing techniques and their applications in gene therapies and regenerative medicine. 3) Case studies. This section discusses the applications and success of all the above-mentioned strategies on selected human disorders. This book serves as a handy reference for students and academics studying advanced omics techniques in biochemistry and molecular genetics as part of courses in life sciences, pharmacology and medicine.

Pulmonomics: Omics Approaches for Understanding Pulmonary Diseases

Author : Sudipto Saha
Publisher : Springer Nature
ISBN 13 : 9819935059
Total Pages : 411 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Pulmonomics: Omics Approaches for Understanding Pulmonary Diseases by : Sudipto Saha

Download or read book Pulmonomics: Omics Approaches for Understanding Pulmonary Diseases written by Sudipto Saha and published by Springer Nature. This book was released on 2023-12-03 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews various omics approaches like genomics, proteomics, transcriptomics, and metabolomics for understanding pulmonary disease at molecular and systems levels. The initial chapters present the pathogenesis of major pulmonary diseases, namely, obstructive diseases, restrictive diseases, vascular diseases, infectious diseases, and neoplastic carcinoma. The book chapters provide current information about the role of the microbiome and applications of medical imaging, bioinformatics tools, and databases for diagnosis and designing treatment strategies against complex lung diseases. Further, the book discusses omics technologies to identify biomarkers for the early diagnosis and prognosis of pulmonary diseases. Finally, the book elucidates the multi-omics approaches and data integration using mathematical modeling for insights into the disease etiology towards improving the prognostics and predictive accuracy of disease phenotypes.

Genetics and Evolution of Infectious Diseases

Author : Michel Tibayrenc
Publisher : Elsevier
ISBN 13 : 0443288194
Total Pages : 1002 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Genetics and Evolution of Infectious Diseases by : Michel Tibayrenc

Download or read book Genetics and Evolution of Infectious Diseases written by Michel Tibayrenc and published by Elsevier. This book was released on 2024-07-19 with total page 1002 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. - Takes an integrated approach to infectious diseases - Provides the latest developments in the field of infectious diseases - Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases - Includes updated and revised contributions from leading authorities, along with six new chapters

Global Catastrophic Biological Risks

Author : Thomas V. Inglesby
Publisher : Springer
ISBN 13 : 9783030363109
Total Pages : 128 pages
Book Rating : 4.3/5 (631 download)

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Book Synopsis Global Catastrophic Biological Risks by : Thomas V. Inglesby

Download or read book Global Catastrophic Biological Risks written by Thomas V. Inglesby and published by Springer. This book was released on 2019-12-12 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on Global Catastrophic Biological Risks (GCBRs), a special class of infectious disease outbreaks or pandemics in which the combined capacity of the world’s private and government resources becomes severely strained. These events, of which the 1918 influenza pandemic is emblematic, cause severe disruptions in the normal functioning of the world, exact heavy tolls in terms of morbidity and mortality, and lead to major economic losses. GCBRs can be caused by any type of microorganism, and myriad contextual factors can influence their impact. Additionally, there are cascading questions that arise in connection with GCBR prediction, preparation, and response. This book gathers contributions from thought leaders who discuss the multi-faceted approaches needed in order to address this problem. From understanding the special characteristics of various microbes to financing challenges, the volume provides an essential primer on a neglected but highly relevant topic. Physicians, scientists, policymakers, public health practitioners and anyone with an interest in the field of pandemics, emerging infectious disease, biosecurity, and global health security will find it a valuable and insightful resource.

Omics Technologies and Bio-engineering

Author : Debmalya Barh
Publisher : Academic Press
ISBN 13 : 0128047496
Total Pages : 645 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Omics Technologies and Bio-engineering by : Debmalya Barh

Download or read book Omics Technologies and Bio-engineering written by Debmalya Barh and published by Academic Press. This book was released on 2017-12-01 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care. - Covers various aspects of biotechnology and bio-engineering using omics technologies - Focuses on the latest developments in the field, including biofuel technologies - Provides key insights into omics approaches in personalized and precision medicine - Provides a complete picture on how one can utilize omics data in molecular biology, biotechnology and human health care

The Microbiota in Gastrointestinal Pathophysiology

Author : Martin H. Floch
Publisher : Academic Press
ISBN 13 : 0128040629
Total Pages : 444 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Microbiota in Gastrointestinal Pathophysiology by : Martin H. Floch

Download or read book The Microbiota in Gastrointestinal Pathophysiology written by Martin H. Floch and published by Academic Press. This book was released on 2016-11-16 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research. - Explains how to modify the gut microbiota and how the current strategies used to do this produce their effects - Explores the gut microbiota as a therapeutic target - Provides the synthesis of existing data from both mainstream and non-mainstream sources through experienced researchers in the field - Serves as a 'one-stop' shop for a topic that's currently spread across a number of various journals